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ABSTRACT This study was conducted to investigate the effects of dietary propolis alcohol extract supplementation on growth performance, digestibility, intestinal morphometry, and physiologic parameters Nile tilápia (Oreochromis niloticus L.) juveniles. For performance experiment and intestinal morphometry, 120 fish averaging 1.41±0.3g were randomly distributed into 24 tanks (70L each) in a closed recirculation water system with constant aeration and biofilter. The animals were distributed into four treatments using a completely randomized design with six replicates per treatment. The treatments consisted of four pellet feeds with different alcohol propolis concentrations extract (AEP) (0.0, 0.5, 1.0 and 1.5gkg-1). The performance experiment period was conducted for 45 days. For the digestibility experiment, an inert marker in the feed and the adapted Guelph feces collecting system were used. The results showed no differences in the performance parameters, crude protein apparent digestibility and dry matter of the feeds, intestinal morphometry, and physiologic parameters. However, there was an increasing linear effect on the energy digestibility with increasing PAE concentrations in the fish feed. The usage of the propolis extract supplementation levels of 1% is recommended for optimum effect on villus morphometry in Nile tilapia.

Sixty dogs with idiopathic dilated cardiomyopathy were randomly treated with traditional therapy - digitalis, diuretics, angiotensin-converting inhibitors - (group A) or treated with these drugs plus carvedilol (group B). Echocardiographic variables were measured before and after 3, 13, 26, and 52 weeks of treatment or until death. Comparisons between groups and time were performed. No significant differences between groups were found in the most of the echocardiographic variables. The left ventricular end-systolic diameter indexed to body surface area (LVESDi) increased significantly in the group A dogs compared to the group B animals. The survival of groups A and B dogs were not different (P-value=0.1137). In conclusion, the stability of the LVESDi observed in the group treated with carvedilol may represent the beneficial effect over the ventricular remodeling.Sessenta cães com cardiomiopatia dilatada idiopática receberam, aleatoriamente, tratamento convencional - digitálicos, diuréticos, inibidores da enzima conversora de angiotensina - (grupo A) ou esses fármacos mais carvedilol (grupo B). As variáveis ecocardiográficas foram avaliadas antes e depois de três, 13, 26 e 52 semanas de tratamento ou até o óbito. Não foram encontradas diferenças significativas entre os grupos de animais quanto à maioria das variáveis ecocardiográficas. O diâmetro sistólico final do ventrículo esquerdo indexado à superfície corpórea (DSVEi) aumentou de forma significativa no grupo A quando comparado ao grupo B. Não se observou diferença na sobrevida dos grupos A e B (P=0,1137). Concluiu-se que a estabilização do DSVEi no grupo tratado com carvedilol pode representar o efeito benéfico deste fármaco sobre o remodelamento ventricular.

Caracterizou-se monitorização eletrocardiográfica ambulatorial por 24 horas (ou monitorização Holter) em cães com cardiomiopatia dilatada idiopática, visando principalmente à detecção de arritmias ventriculares não detectadas pela eletrocardiografia convencional (de repouso). Para tanto, avaliaram-se 40 pacientes com diagnóstico de cardiomiopatia dilatada idiopática, por meio de exame físico e mensuração indireta da pressão arterial, além de exames eletrocardiográfico, ecocardiográfico, radiográfico de tórax e da monitorização Holter. Extra-sístoles ventriculares foram detectadas, por monitorização Holter, em 97,5% dos animais e taquicardia ventricular, em 45%. Não houve correlação entre o número de extra-sístoles ventriculares e a fração de encurtamento. Considerando as manifestações clínicas, apenas houve associação entre presença de taquicardia ventricular e histórico de síncopes. Conclui-se que a incidência de arritmias ventriculares em cães com cardiomiopatia dilatada idiopática é bastante alta, sendo a taquicardia ventricular relativamente freqüente, ocorrendo mais sob a forma não sustentada.This study aimed to characterize 24-hour ambulatory electrocardiographic monitoring (Holter monitoring) in dogs with idiopathic dilated cardiomyopathy. Physical examination and indirect (Doppler) blood pressure measurement, and also electrocardiography, thoracic radiography, echocardiography, and 24-hour ambulatory electrocardiographic exams were performed in 40 dogs with idiopathic dilated cardiomyopathy. Ventricular extrasystoles were detected in 97.5% of the animals, and ventricular tachycardia in 45%. No correlation between the number of ventricular extrasystoles and the shortening fraction was observed. Concerning the clinical symptoms, there was only association between the presence of ventricular tachycardia and past report of syncope. It was concluded that the incidence of ventricular arrhythmias is high in dogs with dilated cardiomyopathy, being ventricular tachycardia, mostly non-sustained, relatively frequent.

Avaliaram-se alguns parâmetros ecocardiográficos em modos B, M e Doppler de 27 gatos-do-mato, Leopardus tigrinus, pequeno felídeo selvagem, mantidos em cativeiro e submetidos à anestesia com 1 a 2mg/kg de xilazina e 10mg/kg de quetamina. Observaram-se alterações dos parâmetros cardiovasculares quando os resultados foram comparados aos do gato doméstico (Felis catus) não anestesiado.Some echocardiographic parameters in B, M-mode and Doppler of 27 Oncillas, Leopardus tigrinus, a wild little feline, kept in captivity and submitted to anesthesia with 1 to 2mg/kg of xilazine and 10mg/kg of ketamine, had been evaluated. Changes of the cardiovascular parameters were observed when the results were compared to non anesthetized domestic cat (Felis catus).

Echocardiographic aspects of chronic mitral valvular disease were studied and compared to physical, radiographic and electrocardiographic aspects. Seventy dogs were used, and clinical examination, thoracic radiography, electrocardiogram and echocardiogram were performed. Correlations between regurgitation severity with cardiac failure functional class and murmur intensity were observed. The electrocardiogram showed a low sensibility in detecting cardiac chamber enlargement, caused by mitral regurgitation. All the dogs with severe mitral regurgitation showed cardiomegaly according to thoracic radiographies.Avaliaram-se os aspectos ecocardiográficos da doença valvar crônica, comparando-os com os aspectos clínicos, radiográficos e eletrocardiográficos em cães. Estudaram-se 70 animais, realizando-se exames físicos, radiografias torácicas, eletrocardiograma e ecocardiograma. Observaram-se correlações entre a gravidade da regurgitação, a classe funcional da insuficiência cardíaca e a intensidade de sopro. O eletrocardiograma mostrou baixa sensibilidade para detectar aumento de câmaras cardíacas causadas por regurgitação mitral. Todos os cães com regurgitação mitral grave apresentaram cardiomegalia nas radiografias torácicas.