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465 results on '"Engelmann, K."'

1. To Peel or Not to Peel: Pars Plana Vitrectomy with Macular Membrane Peel in Eyes with Abnormalities of Vitreomacular Interface and Coexisting Dry Age-Related Macular Degeneration

Author

Furashova O and Engelmann K

Subjects
macular membrane peel, choroidal neovascularization, pars plana vitrectomy, age-related macular degeneration, ilm- and epiretinal membrane peeling, Ophthalmology, RE1-994
Abstract

Olga Furashova, Katrin Engelmann Department of Ophthalmology, Klinikum Chemnitz gGmbH, Chemnitz, GermanyCorrespondence: Olga FurashovaDepartment of Ophthalmology, Klinikum Chemnitz gGmbH, Flemmingstrasse 2, Chemnitz 09116, GermanyTel +49 371 333 33230Fax +49 371 333 33223Email fur.olga@gmail.comPurpose: To evaluate the outcome of macular surgery with ILM- and epiretinal membrane peel associated with significant dry age-related macular degeneration (AMD) as defined by the Age-Related Eye Disease Study (AREDS).Patients and Methods: Institutional. Retrospective case-control study. A total of 42 pseudophacic eyes of 39 patients (7 with full thickness macular hole and 35 with epiretinal membrane) with coexisting dry AMD underwent pars plana vitrectomy (PPV) with internal limiting membrane (ILM) and epiretinal membrane peel. Preoperative and postoperative data including best corrected visual acuity (BCVA), AMD grade according to AREDS, central retinal thickness (CRT), development of choroidal neovascularization (CNV), and central retinal atrophy have been evaluated. Twenty-eight fellow eyes with dry AMD of the included 39 patients served as a control group.Results: A significant improvement in the visual acuity could be observed after surgery (initial BCVA 0.47± 0.31 logarithm of the minimal angle of resolution (logMAR) vs 0.33± 0.29logMAR 9 months postoperatively; p=0.006). CRT decreased significantly after surgery (p< 0.001). In the surgery group, there were 4 eyes (9.5%) with CNV and 1 eye (2.5%) with new central retinal atrophy development after surgery. All these eyes had preoperative AREDS 3 (4 eyes) or AREDS 4 (1 eye) AMD category. In the control group, there was 1 eye (4%) with CNV and 4 eyes (14%) with new central retinal atrophy development during the follow-up of 9 months. These eyes had initially AREDS 2 (1 eye), AREDS 3 (3 eyes) or AREDS 4 (1 eye) AMD category.Conclusion: Eyes with dry AMD of AREDS 3 and AREDS 4 with coexisting VMI abnormalities improve significantly after PPV with membrane peel. While there is a higher risk of CNV development after surgery (9.5%) in these eyes, the vitrectomy does not seem to accelerate central retinal atrophy progression compared to the fellow eyes course.Keywords: macular membrane peel, choroidal neovascularization, pars plana vitrectomy, age-related macular degeneration, ILM, epiretinal membrane peeling

Published
2020

5. Systemische und ophthalmologische Komplikationen innerhalb der ersten 7 Tage nach Behandlung einer Frühgeborenenretinopathie – erste Daten aus dem neu etablierten EU-ROP Register

Author

Pfeil, JM, Engmann, HD, Meyer, J, Breuss, H, Hufendiek, K, Uzun, A, Grundel, M, Glitz, B, Barth, T, Kakkassery, V, Suesskind, D, Khattab, M, Skevas, C, Lagrèze, WA, Engelmann, K, Walter, P, Krohne, TU, Mihailovic, N, Stahl, A, and EU-ROP Register Studiengruppe

Subjects
ddc: 610, Medicine and health
Abstract

Hintergrund: In den letzten Jahren wurden mehrere interventionelle Studien zur Frühgeborenenretinopathie (ROP) durchgeführt. International vergleichbare real-life Daten sind allerdings weiterhin kaum verfügbar. Deshalb wurde 2021 das Retina.net ROP Register für die Teilnahme aus [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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8. Lasers in General Surgery

Author

Schmitz, Sabine D., Algermissen, B., Vogl, T.J., Mack, M.G., Straub, R., Eichler, K., Engelmann, K., Zangos, S., Heß, S., Roggan, A., Berlien, H.-Peter, editor, and Müller, Gerhard J., editor

Published
2003
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10. Das Deutsche Akanthamöbenkeratitis-Register: Erste Ergebnisse einer multizentrischen Erhebung

Author

Daas, L., Szentmáry, N., Eppig, T., Langenbucher, A., Hasenfus, A., Roth, M., Saeger, M., Nölle, B., Lippmann, B., Böhringer, D., Reinhard, T., Kelbsch, C., Messmer, E., Pleyer, U., Roters, S., Zhivov, A., Engelmann, K., Schrecker, J., Zumhagen, L., Thieme, H., Darawsha, R., Meyer-ter-Vehn, T., Dick, B., Görsch, I., Hermel, M., Kohlhaas, M., and Seitz, B.

Published
2015
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13. AmnioClip-plus ermöglicht Amnionmembranbehandlung ohne Trauma

Author

Hofmann, Nicola, Möhle, N., Wittmershaus, I., Hofmann, K., Diedenhofen, N., Engelmann, K., and Börgel, M.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Um Oberflächenstörungen des Auges alternativ zur pharmakologischen Therapie zu behandeln, ist die Amnionmembrantransplantation (AMT) seit langem etabliert. De Röth beschrieb die Anwendung erstmals 1940. Seitdem hat sich die AMT durch die wertvollen antientzündlichen [zum vollständigen Text gelangen Sie über die oben angegebene URL], Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft

Published
2020

14. From Cord to Eye: Wharton Jelly-Derived Stem Cells Differentiate Into Corneal Endothelial-Like Cells

Author

Feiertag, E., Maassen, J., Mueller, A., Harnisch, E., Skazik-Voogt, C., Engelmann, K., Schrage, N., Gutermuth, A., and Publica

Abstract

PURPOSE: A malfunction of the corneal endothelium leading to corneal opacity is one of the main causes of impaired vision. Currently, keratoplasty is the one and only donor cornea-dependent treatment, and this calls for alternatives because of the worldwide lack of donor corneas. Recently, the topography of Descemet membrane (DM) has been discovered as a feasible stem cell differentiation tool. With this study, we further confirm this mechanotransductive system by using preinduced Wharton jelly-derived mesenchymal stem cells (WJ-EPCs). METHODS: To measure the mechanotransductive potential of Descemet-like topography (DLT), WJ-EPCs were cultivated on collagen imprints with DLT. Changes in the gene and protein expressions of corneal endothelial cells (CECs), typical markers such as zonula occludens (ZO-1), sodium/potassium (Na/K)-ATPase, paired-like homeodomain 2 (PITX2), and collagen 8 (COL-8) were measured. In addition, CEC functionality has been evaluated by measuring the relative potential differences in a 2-compartment system and by measuring corneal transparency in an ex vivo rabbit cornea model. To confirm the activity of WJ-EPCs, rabbit CECs were restless deleted by collagen digestion of a thin layer of rabbit Descemet membrane. RESULTS: The proper CEC-typical hexagonal morphology of WJ-EPCs in combination with a significant expression of ZO-1, Na/K-ATPase, PITX2, and COL-8 could be demonstrated. In addition, the WJ-EPCs were able to build up a relative potential difference of 40 mV and to keep corneas clear and transparent. CONCLUSIONS: These data indicate that a well-characterized, functional CEC monolayer was developed by using a DLT-mediated mechanotransductive differentiation of WJ-EPCs.

Published
2020

15. Facilitating self-regulated learning with personalized scaffolds on student's own regulation activities

Author

Graaf, J. van der, Molenaar, I., Lim, L., Fan, Y., Engelmann, K., Gasevic, D., Bannert, M., Giannakos, M., Spikol, D., Di Mitri, D., Sharma, K., Ochoa, X., Hammad, R., Giannakos, M., Spikol, D., Molenaar, I., Di Mitri, D., Sharma, K., Ochoa, X., and Hammad, R.

Subjects
Learning and Plasticity
Abstract

Item does not contain fulltext The focus of education is increasingly set on students' ability to regulate their own learning within technology-enhanced learning environments. Scaffolds have been used to foster self-regulated learning, but scaffolds often are standardized and do not do not adapt to the individual learning process. Learning analytics and machine learning offer an approach to better understand SRL-processes during learning. Yet, current approaches lack validity or require extensive analysis after the learning process. The FLORA project aims to investigate how to advance support given to students by i) improving unobtrusive data collection and machine learning techniques to gain better measurement and understanding of SRL-processes and ii) using these new insights to facilitate student’s SRL by providing personalized scaffolds. We will reach this goal by investigating and improving trace data in exploratory studies (exploratory study 1 and study 2) and using the insight gained from these studies to develop and test personalized scaffolds based on individual learning processes in laboratory (experimental study 3 and study 4) and a subsequent field study (field study 5). At the moment study 2 is ongoing. The setup consists of a learning environment presented on a computer with a screen-based eye-tracker. Other data sources are log files and audio of students’ think aloud. The analysis will focus on detecting sequences that are indicative of micro-level self-regulated learning processes and aligning them between the different data sources. CrossMMLA 2020 (24 March 2020)

Published
2020

17. Facilitating self-regulated learning with personalized scaffolds on student's own regulation activities

Author

Giannakos, M., Spikol, D., Molenaar, I., Di Mitri, D., Sharma, K., Ochoa, X., Hammad, R., Graaf, J. van der, Lim, L., Fan, Y., Engelmann, K., Gasevic, D., Bannert, M., Giannakos, M., Spikol, D., Molenaar, I., Di Mitri, D., Sharma, K., Ochoa, X., Hammad, R., Graaf, J. van der, Lim, L., Fan, Y., Engelmann, K., Gasevic, D., and Bannert, M.

Abstract

CrossMMLA 2020 (24 March 2020), Item does not contain fulltext, The focus of education is increasingly set on students' ability to regulate their own learning within technology-enhanced learning environments. Scaffolds have been used to foster self-regulated learning, but scaffolds often are standardized and do not do not adapt to the individual learning process. Learning analytics and machine learning offer an approach to better understand SRL-processes during learning. Yet, current approaches lack validity or require extensive analysis after the learning process. The FLORA project aims to investigate how to advance support given to students by i) improving unobtrusive data collection and machine learning techniques to gain better measurement and understanding of SRL-processes and ii) using these new insights to facilitate student’s SRL by providing personalized scaffolds. We will reach this goal by investigating and improving trace data in exploratory studies (exploratory study 1 and study 2) and using the insight gained from these studies to develop and test personalized scaffolds based on individual learning processes in laboratory (experimental study 3 and study 4) and a subsequent field study (field study 5). At the moment study 2 is ongoing. The setup consists of a learning environment presented on a computer with a screen-based eye-tracker. Other data sources are log files and audio of students’ think aloud. The analysis will focus on detecting sequences that are indicative of micro-level self-regulated learning processes and aligning them between the different data sources.

Published
2020

40. Nahtlose Amnionmembrantransplantation mit AmnioClip-plus

Author

Hofmann, Nicola, Möhle, N., Wittmershaus, I., Hofmann, K., Engelmann, K., and Börgel, M.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Amnionmembrantransplantation (AMT) ist zur Behandlung von Oberflächenstörungen des Auges neben der pharmakologischen Therapie seit langem etabliert. Seit der ersten von de Röth 1940 beschriebenen Anwendung hat sich diese Therapie durch die wertvollen antientzündlichen[zum vollständigen Text gelangen Sie über die oben angegebene URL], 27. Jahrestagung der Regionalgesellschaft der Augenärzte Sachsen-Anhalts und Thüringens e. V.

Published
2019

41. To Peel or not to Peel: Ergebnisse der Makulachirurgie mit Peeling der epiretinalen Membranen in Augen mit zusätzlicher Drusenmakulopathie

Author

Furashova, Olga and Engelmann, K.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Untersuchung der chirurgischen Ergebnisse, insbesondere der Entwicklung der choroidalen Neovaskularisation (CNV) und zentralen Atrophie nach Peeling der epiretinalen Membranen in Augen mit intermediären und großen Drusen nach Age-Related Eye Disease Study (AREDS) Klassifikation.[zum vollständigen Text gelangen Sie über die oben angegebene URL], 32. Jahrestagung der Retinologischen Gesellschaft

Published
2019
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42. AmnioClip-plus ermöglicht Amnionmembrantransplantation ohne Trauma

Author

Hofmann, Nicola, Möhle, N., Polster, F., Koch, I., Hofmann, K., Engelmann, K., and Börgel, M.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Oberflächenstörungen des Auges können zu Defekten der Hornhaut führen, sind häufig schwer therapierbar und können zur Eintrübung der Hornhaut mit konsekutiver Sehminderung oder Erblindung führen. Bei Wundheilungsstörungen sind meist aufwändige[zum vollständigen Text gelangen Sie über die oben angegebene URL], 69. Tagung der Vereinigung Norddeutscher Augenärzte (VNDA)

Published
2019
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43. Vorderkammer- und Glaskörperprobenuntersuchung – eine diagnostische Herausforderung aus kleinsten Probenmengen mit Neuauflage in der Region

Author

Diedenhofen, N, Engelmann, K, Borte, S, and Günther, G

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Untersuchung von Vorderkammer- und Glaskörperflüssigkeiten stellt eine große Herausforderung in unserem Fachgebiet dar. Ursache hierfür sind kleinste Probenvolumina, als auch die nur wenig existenten diagnostischen Zentren. Insbesondere im Rahmen des primär [zum vollständigen Text gelangen Sie über die oben angegebene URL], Jahrestagung 2018 der Sächsischen Augenärztlichen Gesellschaft

Published
2018
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44. Erratum zu: Das Deutsche Akanthamöbenkeratitis-Register: Erste Ergebnisse einer multizentrischen Erhebung

Author

Daas, L., Szentmáry, N., Eppig, T., Langenbucher, A., Hasenfus, A., Roth, M., Saeger, M., Nölle, B., Lippmann, B., Böhringer, D., Reinhard, T., Kelbsch, C., Messmer, E., Pleyer, U., Roters, S., Zhivov, A., Engelmann, K., Schrecker, J., Zumhagen, L., Thieme, H., Darawsha, R., Meyer-ter-Vehn, T., Dick, B., Görsch, I., Hermel, M., Kohlhaas, M., and Seitz, B.

Published
2015
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48. 3-year results of the German nationwide survey on eye injuries caused by fireworks

Author

Gabel-Pfisterer, A., Boehringer, D., Agostini, H., Fuest, M., Walter, P., Botros, Y., Mueller, A., Al-Ashi, N., Lenglinger, M., Mueller, B., Schoenfeld, S., Seibel, I., Joussen, A., Breuss, H., Kuchenbecker, J., Foerster, M. H., Berthold, A., Wirbelauer, C., Hofmayer, H., Wachtlin, J., Palka, K., Niemeyer, M., Walla, T., Pham, D., Aisenbrey, S., Tatsiou, A., Walch, A., Burk, R., Schultz, T., Tsiampalis, N., Rehmann, J., Sliwowska, U., Schojai, M., Schulze, K., Kamguia, N., Wirtz, C., Dick, B., Voelker, D., Wintergerst, M., Pfau, M., Melzer, C., Hoegen, D., Bosch, F., Andresen, J. C., Krohne, T., Holz, F., Kathke, M., Sturm, A., Noske, W., Huebner, T., Brandner, S., Feldmann, M., Morsek, J., Rainer, O., Bartsch, H., Ewald, K., Chankiewitz, E., Siegmund, T., Bohlen, A., Mohr, A., Hecker, J., Strassburger, P., Furashova, O., Engelmann, K., Krieb, A., Emmerich, K., Grajewski, L., Krause, L., Jabur, A., Ruediger, K., Lehmann, F., Sachs, H., Matthee, E., Steindorf, F., Schnitzler, C., Neumann, I., Korbmacher, J., Geerling, G., Doulgkeridis, J., Erhard, J., Dahms-Dowidat, K., Kotiasvili, T., Jagow, B. V., Lieder, A., Blum, M., Westerkemper, H., Boehm, M., Bornfeld, N., Bechrakis, N., Schultheiss, M., Scheider, A., Mueller, M., Kohnen, T., Eckert, T., Eckardt, C., Wisniewska, M., Just, A., Jehle, V., Reinhard, T., Seewald, J., Mais, C., Basiakos, S., Osman, B., Xanthopoulou, E., Friedburg, B., Graef, M., Lorenz, B., Just, U., Naxer, S., Oterendorp, C., Bemme, S., Callizo, J., Feltgen, N., Hoerauf, H., Menges, A., Tost, F., Stahl, A., Huth, A., Viestenz, A., Bertram, P., Skevas, C., Kromer, R., Casagrande, M., Grohmann, C., Mehlan, J., Schindler, P., Spitzer, M., Schargus, M., Eddy, M., Schumacher, S., Keserue, M., Scheler, A., Stemplewitz, B., Schaudig, U., Abou Moulig, W., Framme, C., Rosenthal, A., Hesse, L., Kunz, L., Spira, C., Suffo, S., Seitz, B., Wietstock, G., Augsten, R., Meller, D., Mayer, M., Vanselow, K., Lieb, W., Beutner, A., Effert, R., Ehlken, C., Roider, J., Hueber, A., Cursiefen, K., Schrage, N., Kroeger, M., Viehweg, N., Meier, P., Unterlauft, J. D., Wiedemann, P., Hattenbach, L., Kakkassery, V., Ranjbar, M., Mohi, A., Grisanti, S., Bastron, I., Sarac, S., Kaskel-Paul, S., Stoffelns, B., Schuster, A., Pfeiffer, N., Schulze, S., Praskevas, A., Sekundo, W., Weigel, M., Thieme, H., Wolf, A., Vounotrypidis, E., Priglinger, S., Bechstein, L., Maier, M., Lohmann, C., Haritoglu, C., Alten, F., Eter, N., Klishko, V., Holland, U., Medra, A., Weber, A., Hoeh, H., Schmidbauer, J., RiveraGomez, C., Plantzas, K., Weiss, M., Hille, K., Hoehn, F., Schrader, M., Napholz, A., Tandogan, T., Walter, C., Zuehlsdorff-Uthke, M., Liekfeld, A., Blecha, C., Barth, T., Helbig, H., Juenemann, A., Decker, A., Kuehn, M., Ladewig, M., Lenhard, K., Lackner, B., Gekeler, F., Holzschuh, I., Boden, K. T., Szurmann, P., Faul, D., May-Endres, K., Press, U., Luttke, J., Ziemssen, F., Bartz-Schmidt, U., Cordes, J., Raber, F., Mikielewicz, M., Kammerer, J., Kupferschmid, S., Buchwald, H., Werner, J., Kampmeier, J., Bula, A., Krauss, P., Strzalkowski, P., Hillenkamp, J., Gabel-Pfisterer, A., Boehringer, D., Agostini, H., Fuest, M., Walter, P., Botros, Y., Mueller, A., Al-Ashi, N., Lenglinger, M., Mueller, B., Schoenfeld, S., Seibel, I., Joussen, A., Breuss, H., Kuchenbecker, J., Foerster, M. H., Berthold, A., Wirbelauer, C., Hofmayer, H., Wachtlin, J., Palka, K., Niemeyer, M., Walla, T., Pham, D., Aisenbrey, S., Tatsiou, A., Walch, A., Burk, R., Schultz, T., Tsiampalis, N., Rehmann, J., Sliwowska, U., Schojai, M., Schulze, K., Kamguia, N., Wirtz, C., Dick, B., Voelker, D., Wintergerst, M., Pfau, M., Melzer, C., Hoegen, D., Bosch, F., Andresen, J. C., Krohne, T., Holz, F., Kathke, M., Sturm, A., Noske, W., Huebner, T., Brandner, S., Feldmann, M., Morsek, J., Rainer, O., Bartsch, H., Ewald, K., Chankiewitz, E., Siegmund, T., Bohlen, A., Mohr, A., Hecker, J., Strassburger, P., Furashova, O., Engelmann, K., Krieb, A., Emmerich, K., Grajewski, L., Krause, L., Jabur, A., Ruediger, K., Lehmann, F., Sachs, H., Matthee, E., Steindorf, F., Schnitzler, C., Neumann, I., Korbmacher, J., Geerling, G., Doulgkeridis, J., Erhard, J., Dahms-Dowidat, K., Kotiasvili, T., Jagow, B. V., Lieder, A., Blum, M., Westerkemper, H., Boehm, M., Bornfeld, N., Bechrakis, N., Schultheiss, M., Scheider, A., Mueller, M., Kohnen, T., Eckert, T., Eckardt, C., Wisniewska, M., Just, A., Jehle, V., Reinhard, T., Seewald, J., Mais, C., Basiakos, S., Osman, B., Xanthopoulou, E., Friedburg, B., Graef, M., Lorenz, B., Just, U., Naxer, S., Oterendorp, C., Bemme, S., Callizo, J., Feltgen, N., Hoerauf, H., Menges, A., Tost, F., Stahl, A., Huth, A., Viestenz, A., Bertram, P., Skevas, C., Kromer, R., Casagrande, M., Grohmann, C., Mehlan, J., Schindler, P., Spitzer, M., Schargus, M., Eddy, M., Schumacher, S., Keserue, M., Scheler, A., Stemplewitz, B., Schaudig, U., Abou Moulig, W., Framme, C., Rosenthal, A., Hesse, L., Kunz, L., Spira, C., Suffo, S., Seitz, B., Wietstock, G., Augsten, R., Meller, D., Mayer, M., Vanselow, K., Lieb, W., Beutner, A., Effert, R., Ehlken, C., Roider, J., Hueber, A., Cursiefen, K., Schrage, N., Kroeger, M., Viehweg, N., Meier, P., Unterlauft, J. D., Wiedemann, P., Hattenbach, L., Kakkassery, V., Ranjbar, M., Mohi, A., Grisanti, S., Bastron, I., Sarac, S., Kaskel-Paul, S., Stoffelns, B., Schuster, A., Pfeiffer, N., Schulze, S., Praskevas, A., Sekundo, W., Weigel, M., Thieme, H., Wolf, A., Vounotrypidis, E., Priglinger, S., Bechstein, L., Maier, M., Lohmann, C., Haritoglu, C., Alten, F., Eter, N., Klishko, V., Holland, U., Medra, A., Weber, A., Hoeh, H., Schmidbauer, J., RiveraGomez, C., Plantzas, K., Weiss, M., Hille, K., Hoehn, F., Schrader, M., Napholz, A., Tandogan, T., Walter, C., Zuehlsdorff-Uthke, M., Liekfeld, A., Blecha, C., Barth, T., Helbig, H., Juenemann, A., Decker, A., Kuehn, M., Ladewig, M., Lenhard, K., Lackner, B., Gekeler, F., Holzschuh, I., Boden, K. T., Szurmann, P., Faul, D., May-Endres, K., Press, U., Luttke, J., Ziemssen, F., Bartz-Schmidt, U., Cordes, J., Raber, F., Mikielewicz, M., Kammerer, J., Kupferschmid, S., Buchwald, H., Werner, J., Kampmeier, J., Bula, A., Krauss, P., Strzalkowski, P., and Hillenkamp, J.

Abstract

Background On festive days worldwide eyes are severely injured by fireworks. The data on the number and severity are to date not registered in Germany. Objective How frequent are firework-induced injuries in Germany, who are the affected, how serious are the injuries, which forms of treatment are necessary and how frequent are accompanying injuries? Method A German nationwide online-based survey was carried out in all inpatient eye departments and data over the last 3 consecutive years were descriptively analyzed. Results From New Years Eve 2016/2017, when 41 eye departments sent in data, the participation could be increased to 51 eye departments in 2018/2019. More than one third (33-39%) of all 1356 patients over 3 years were minors, 60% were younger than 25 years old and roughly 60% of patients were injured as bystanders or in an unclear situation. In total 25% of all eye injuries were considered severe and required inpatient treatment. Accompanying injuries of the other eye, the face and hands were more frequent in minors than in adults. Eyeball ruptures were reported in 10 minors and 38 adults over the 3 years. Conclusion Particularly minors and bystanders need better protection.

Published
2019

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