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219 results on '"Gandon Y"'

2. Suspicious liver nodule in chronic liver disease: Usefulness of a second biopsy

Author

Anty, R., Archambeaud, I., Baudin, G., Brun, V., Chevallier, P., Cuilleron, M., Dumortie, J., Duvoux, C., Estivalet, L., Frampas, E., Gandon, Y., Guillygomarc’h, A., Guiu, B., Lebigot, J., Le Pennec, V., Luciani, A., Minello, A., Ollivier-Hourmand, I., Pilleul, F., Patouillard, B., Sylvain, C., Tasu, J.P., Cartier, V., Crouan, A., Esvan, M., Oberti, F., Michalak, S., Gallix, B., Seror, O., Paisant, A., Vilgrain, V., and Aubé, C.

Published
2018
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7. P1566: PROTON PUMP INHIBITION FOR SECONDARY HEMOCHROMATOSIS IN HEREDITARY ANEMIA, A PHASE III PLACEBO-CONTROLLED RANDOMIZED CROSS-OVER CLINICAL TRIAL

Author

Van Vuren, A., primary, Kerkhoffs, J., additional, Schols, S., additional, Rijneveld, A., additional, Nur, E., additional, Peereboom, D., additional, Gandon, Y., additional, Welsing, P., additional, van Wijk, R., additional, Schutgens, R., additional, van Solinge, W., additional, Marx, J., additional, Leiner, T., additional, Biemond, B., additional, and van Beers, E., additional

Published
2022
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8. Proton pump inhibition for secondary hemochromatosis in hereditary anemia: a phase III placebo-controlled randomized cross-over clinical trial

Author

Vuren, A. van, Kerkhoffs, J.L.H., Schols, S.E.M., Rijneveld, A., Nur, E., Peereboom, D., Gandon, Y., Welsing, P., Wijk, R. Gerth van, Schutgens, R., Solinge, W. van, Marx, J., Leiner, T., Biemond, B., Beers, E., Vuren, A. van, Kerkhoffs, J.L.H., Schols, S.E.M., Rijneveld, A., Nur, E., Peereboom, D., Gandon, Y., Welsing, P., Wijk, R. Gerth van, Schutgens, R., Solinge, W. van, Marx, J., Leiner, T., Biemond, B., and Beers, E.

Abstract

Contains fulltext : 251634.pdf (Publisher’s version ) (Open Access), Iron overload is a severe general complication of hereditary anemias. Treatment with iron chelators is hampered by important side-effects, high costs, and the lack of availability in many countries with a high prevalence of hereditary anemias. In this phase III randomized placebo-controlled trial, we assigned adults with non-transfusion-dependent hereditary anemias with mild-to-moderate iron overload to receive esomeprazole (at a dose of 40 mg twice daily) or placebo for 12 months in a cross-over design. The primary end point was change of liver iron content measured by MRI. A total of 30 participants were enrolled in the trial. Treatment with esomeprazole resulted in a statistically significant reduction in liver iron content that was 0.55 mg Fe/g dw larger than after treatment with placebo (95%CI [0.05 to 1.06]; p = 0.03). Median baseline liver iron content at the start of esomeprazole was 4.99 versus 4.49 mg Fe/g dw at start of placebo. Mean delta liver iron content after esomeprazole treatment was -0.57 (SD 1.20) versus -0.11 mg Fe/g dw (SD 0.75) after placebo treatment. Esomeprazole was well tolerated, reported adverse events were mild and none of the patients withdrew from the study due to side effects. In summary, esomeprazole resulted in a significant reduction in liver iron content when compared to placebo in a heterogeneous group of patients with non-transfusion-dependent hereditary anemias. From an international perspective this result can have major implications given the fact that proton pump inhibitors may frequently be the only realistic therapy for many patients without access to or not tolerating iron chelators.

Published
2022

12. Non-invasive assessment of hepatic iron stores by MRI

Author

Gandon, Y., Olivie, D., Guyader, D., Aube, C., Oberti, F., Sebille, V., and Deugnier, Y.

Subjects
Iron in the body -- Measurement, Liver -- Medical examination, Magnetic resonance imaging -- Usage
Published
2004

14. Accuracy of computed tomographic colonography in a nationwide multicentre trial, and its relation to radiologist expertise

Author

Heresbach, D, Djabbari, M, Riou, F, Marcus, C, Le Sidaner, A, Pierredon-Foulogne, M A, Ponchon, T, Boudiaf, M, Seyrig, J A, Laumonier, H, Luet, D, Giraud-Cohen, M, Pelletier, A L, Charachon, A, Ramaholimihaso, F, Bouillet, P, Veyrac, M, Ficarelli, S, Vahedi, K, Keruhel, J, Lamouliatte, H, Ridereau-Zins, C, Bouhnik, Y, Tissier, M, Diris, B, Zagdanski, A M, Josselin, J M, Hamonic, S, and Gandon, Y

Published
2011
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20. Suspicious liver nodule in chronic liver disease: Usefulness of a second biopsy

Author

Cartier, V., primary, Crouan, A., additional, Esvan, M., additional, Oberti, F., additional, Michalak, S., additional, Gallix, B., additional, Seror, O., additional, Paisant, A., additional, Vilgrain, V., additional, Aubé, C., additional, Anty, R., additional, Archambeaud, I., additional, Baudin, G., additional, Brun, V., additional, Chevallier, P., additional, Cuilleron, M., additional, Dumortie, J., additional, Duvoux, C., additional, Estivalet, L., additional, Frampas, E., additional, Gandon, Y., additional, Guillygomarc’h, A., additional, Guiu, B., additional, Lebigot, J., additional, Le Pennec, V., additional, Luciani, A., additional, Minello, A., additional, Ollivier-Hourmand, I., additional, Pilleul, F., additional, Patouillard, B., additional, Sylvain, C., additional, and Tasu, J.P., additional

Published
2018
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21. Métabolisme du fer et outils diagnostiques pour le clinicien [Iron metabolism and tools for the iron status assessment]

Author

Loréal, Olivier, Bardou-Jacquet, E, Jouanolle, A-M, Gandon, Y, Deugnier, Y, Brissot, P, Ropert, M, CHU Pontchaillou [Rennes], Foie, métabolismes et cancer, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Département de Radiologie [CHU de Rennes], Université de Rennes (UR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2012

22. Developmental Dysplasia of the Hip

Author

Tréguier, Catherine, Chapuis, M., Branger, B., Grellier, A., Chouklati, K., Bruneau, B., Fraisse, B., Violas, P., Pladys, Patrick, Darnault, P., Gandon, Y., Service de radiologie et imagerie médicale [Rennes] = Radiology [Rennes], CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Le Corre, Morgane

Subjects
[SDV.IB] Life Sciences [q-bio]/Bioengineering, [SDV.IB]Life Sciences [q-bio]/Bioengineering
Published
2011

24. EURORAD, the EAR database project

Author

Sigal, R, Caramella, Davide, Kurdziel, Jc, Gandon, Y, Lemort, M, Salcito, G, Frija, G, Ringertz, H, Baert, A, and Passariello, R.

Published
1999

26. [Test of a teleradiology network based on ATM (asynchronous transfer mode)]

Author

Jf, Heautot, Tréguier C, Cordonnier E, Joaquim Piqueras, Eichelberg M, Jm, Scarabin, Carsin M, and Gandon Y

Subjects
Europe, Hospitals, University, Computer Communication Networks, Multimedia, Teleradiology, Spain, Research, Humans, France, Pediatrics
Abstract

The retain project (Radiological Examination Transfer on ATM Integrated Network) consisted in teleradiology trials focused on pediatric imaging between two university hospitals. Rennes (France) and Barcelona (Spain) using an integrated broadband communication network based on ATM (asynchronous transfer mode), as part of a European research program. The network used was a full 10 Mbits/s ATM network directly connected to local PACSs (medical imaging hospital networks). One important reason to explicitly consider ATM for medical imaging is that multimedia applications on such networks allow integration of digital data and person-to-person communication. The utility of broadband communication for teleradiology has been confirmed. High quality video and sound are important for both human communication and medical video transfer. The project led to guidelines regarding technical options still open to improvement.

Published
1996

30. Luxation congénitale de hanche chez l’enfant

Author

Tréguier, C., primary, Chapuis, M., additional, Branger, B., additional, Grellier, A., additional, Chouklati, K., additional, Bruneau, B., additional, Fraisse, B., additional, Violas, P., additional, Pladys, P., additional, Darnault, P., additional, and Gandon, Y., additional

Published
2011
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32. Etude multicentrique prospective de la coloscopie virtuelle comparée à la vidéocoloscopie

Author

Heresbach, D, primary, Charachon, A, additional, Marcus, C, additional, Le Sidaner, A, additional, Pierredon-Foulogne, MA, additional, Ponchon, T, additional, Boudiaf, M, additional, Seyrig, JA, additional, Laumonier, H, additional, Burtin, P, additional, Giraud-Cohen, M, additional, Djabbari, M, additional, Ramaholimihaso, F, additional, Bouillet, P, additional, Veyrac, M, additional, Ficarelli, S, additional, Vahedi, K, additional, Keruhel, J, additional, Lamouliatte, H, additional, Ridereau-Zins, C, additional, Bouhnik, Y, additional, Vallot, T, additional, Zagdanski, AM, additional, Riou, F, additional, and Gandon, Y, additional

Published
2010
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48. Imaging Core Lab Comparison of Five Clinical Liver Iron MRI Methods and Biopsy for Hepatic Iron Concentration (HIC) in Sickle Cell Disease (SCD) Patients.

Author

Wood, J., primary, Heverhagen, J., additional, Yang, X., additional, Jia, G., additional, Koch, R.M., additional, Jacko, R., additional, Sammet, S., additional, Enriquez, C., additional, Nord, A., additional, Allegrini, P., additional, Holland, J., additional, Jensen, P.D., additional, Gandon, Y., additional, Pellas, T., additional, Knopp, M., additional, and Cole, P., additional

Published
2006
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