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Hintergrund: Epilepsie ist eine der häufigsten neurologischen Erkrankungen. Zu den wichtigsten Zielgrößen der Behandlung zählen die Anfallsfreiheit oder zumindest -reduktion sowie die gesundheitsbezogene Lebensqualität der Patient*innen. Therapieziele und -nutzen von Patient*innen [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Objective: Reoperations in patients with failed epilepsy surgery are still challenging although a reasonable good seizure outcome seems possible. Advanced imaging and intraoperative MR tomography may contribute to a better postoperative seizure outcome in this patient group. Methods: We investigated[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Objective: Epilepsy surgery for focal cortical dysplasia type II (FCD II) leads to high percentages of seizure free patients, but remains a challenge with respect to lesion detection, defining the epileptogenic zone and the optimal resection strategy. Integrating results from magnetic source imaging[for full text, please go to the a.m. URL], 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Objective: Voxel-based morphometry (VBM) is an important post-processing MRI technique to identify occult malformations in epilepsy patients. We investigated our surgical results in patients operated on for focal cortical dysplasia (FCD) who suffered from refractory epilepsy with the aid of VBM, neuronavigation[for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)

Objective: Intraoperative underestimation of resection amount in epilepsy surgery is a well-known problem, leading to an unfavourable seizure outcome. Intraoperative MR imaging combined with neuronavigation may help to avoid this pitfall and facilitate visualisation and targeting of the sometimes ill-defined[for full text, please go to the a.m. URL], 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)

Objective: Focal cortical dysplasia (FCD) is very frequently associated with epilepsy. However, seizure control after surgery still remains unsatisfactory in most of the cases. We investigated our patient cohort operated on drug-resistant epilepsy caused by FCDs with complementary use of intraoperative[for full text, please go to the a.m. URL], 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)

Objective: Frontal lobe epilepsy (FLE) still remains challenging for surgery. Long-term seizure outcome ranges between 13-47% seizure free patients. The main difficulties are localization of the epileptic zone, protection of eloquent brain areas, and definition of resection borders in MRI negative[for full text, please go to the a.m. URL], 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: Gangliogliomas (GG) are among the most common lesions causing medically refractory epilepsy. Incomplete resection or early recurrences are common in patients with eloquent located tumours resulting in persistent epilepsy. Neuronavigation combined with intraoperative high-field MR imaging [for full text, please go to the a.m. URL], 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Cerebral cavernous malformations (CCMs) are well-defined, mostly singular lesions present in 0.4-0.9% of the population. Epileptic seizures are the most frequent symptom in patients with CCMs and have a great impact on social function and quality of life. However, patients with CCM-related epilepsy (CRE) who undergo surgical resection achieve postoperative seizure freedom in only about 75% of cases. This is frequently because insufficient efforts are made to adequately define and resect the epileptogenic zone. The Surgical Task Force of the Commission on Therapeutics of the International League Against Epilepsy (ILAE) and invited experts reviewed the pertinent literature on CRE. Definitions of definitive and probable CRE are suggested, and recommendations regarding the diagnostic evaluation and etiology-specific management of patients with CRE are made. Prospective trials are needed to determine when and how surgery should be done and to define the relations of the hemosiderin rim to the epileptogenic zone.© 2013 International League Against Epilepsy.

Objective: Lesional temporal lobe epilepsy comprises a heterogeneous group of pathologies, frequently presenting with ill-defined borders or even with multiple lesions. During surgery, intraoperative functional neuronavigation and MR imaging may be of value to optimize the amount of resection and to[for full text, please go to the a.m. URL], 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: Cure from epilepsy due to a cerebral cavernoma may be surgically achieved depending on both, the complete removal of the cavernoma, as well as the hemosiderotic rim around the lesion. Intraoperative MR imaging and neuronavigation may play a crucial role to achieve both goals. Thus, we retrospectively[for full text, please go to the a.m. URL], 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)