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Introduction In February 2009 an outbreak of subcutaneous abscesses due to Mycobacterium abscessus was detected in Spain which affected healthy women who had undergone mesotherapy procedures in an aesthetic clinic. Methods Epidemiological research, health inspection and microbiological studies were conducted. The patients were given antibiotic treatment (according to susceptibility testing) with clarithromycin, and in some cases, combined with amikacin. Results Seventeen out of 77 patients treated in the clinic were affected. The products used for the injections were homeopathic drugs in multi-dose vials. The environmental samples were negative. The sterile injection equipment and the clinical procedures were evaluated as correct. The storage conditions for the drugs were also correct, and all the samples tested negative for Mycobacteria. However Paenibacillus provencensis was isolated from samples of unused multi-dose vials and the withdrawal of the product from distribution was ordered. Deficiencies were detected in the sterile products process of at the homeopathic drug factory, so the production line was suspended. Conclusions The results of environmental investigation suggest the most likely cause of the outbreak could have been the contamination of the products in the factory, although there was no laboratory confirmation. The widespread use of homeopathic products in invasive procedures requires extreme control during the manufacturing, handling and packaging process. It is important to consider mesotherapy and parenteral use of homeopathic medicines as potential sources of infection and therefore the same precautions in the procedures and quality assurance of products should be applied as with any other drug or medical activity.

Fun da men tos: Para un buen de sa rro llo de los pro gra mas de va cu na ción es pri mor dial co nocer la co ber tu ra de va cu na - ción. En las Islas Ba lea res la co ber tu ra no ti fi ca da era muy in fe - rior a la del res to de Espa ña. El ob jetivo de este tra ba jo es la es - ti ma ción de la co bertura de las va cunas in clui das en el ca len da - rio re co men da do has ta los 18 me ses de edad (4 do sis de po lio oral, té tanos y dif te ria; 3 de tos fe ri na; 1 de sa ram pión, ru beo la y pa rotiditis). Mé to dos: Estu dio des crip ti vo, trans ver sal, de base po bla - cio nal. Se cal cu la ron los es ti ma do res pun tua les de dis tri bu ción de fre cuen cias y los in ter va los de con fian za al 95% (IC95%) co rres pon dien tes, so bre una mues tra de la po bla ción re si den te en Ba lea res de dos años de edad (na ci da en 1995), se lec cio na da por mues treo alea to rio por con glo me ra dos en una sola eta pa a par tir de las sec cio nes cen sa les. Se con sul tan los re gis tros de va cu nas de Sa ni dad y de los cen tros de sa lud del Insa lud, se pide te le fó ni ca men te a las fa mi lias los da tos del do cu men to de va cu na ción y a los pe dia tras pri va dos los de la his to ria clí nica. Re sul ta dos: La mues tra in cluía 606 ni ños. Pudo ob te ner se la in for ma ción com ple ta de 532. Se con si guió la in for ma ción com ple ta de 377 ca sos (62%) a par tir de los re gis tros del sec tor pú bli co. La co bertura más baja fue la de la va cu na an ti dif té ri ca, 518 ni ños com plen ta men te va cu na dos, el 96,8% (IC95% = 94,8 ? 98,1) y la más alta la de la va cu na an ti per tus sis, 537 ni - ños, el 98,9% (IC95% = 97,5 ? 99,5). Conclusiones: En las Islas Ba lea res exis te una bue na co - ber tu ra de la va cu na ción, si mi lar a lo que se vie ne es ti man do en Espa ña en su to ta li dad. Se cum ple el ob je ti vo in clui do en el Plan de Erra di ca ción de la Po lio. La in for ma ción re co gi da des - de el sec tor pú bli co es es casa.

In order for vaccination programs to be carried out properly, it is essential for the vaccination coverage to be known. On the Balearic Islands, the reported coverage was much less than for the rest of Spain. The objective of this study is that of estimating the coverage of the vaccinations included on the recommended schedule up to 18 months of age (4 doses of oral polio, tetanus and diphtheria; 3 doses of whooping cough; 1 dose of measles, rubella and mumps).A descriptive, cross-sectional study of the population base. The ideal-time frequency distribution estimators and the corresponding confidence intervals were calculated at 95% (CI95%) for a sample of the resident two-year-old (born in 1995) Balearic Island population selected by means of a single-stage conglomerate random sampling based on census sections. The National Public Health System and National Health Institute vaccination records were reviewed, the data from the vaccination document having been requested from the families and the clinical record from the private pediatricians by telephone.The sample included 606 children, it having been possible to obtain full information on 532 children. Full information was obtained on 377 cases (62%) from the public health sector records. The least degree of coverage was found for the diphtheria vaccine, 518 children having been fully vaccinated, 96.8% (CI95% = 94.8-98.1), the highest degree of coverage having been found for the whooping cough vaccine, 537 children, 98.9% (CI95% = 97.5-99.5).Good vaccination coverage was found to exist on the Balearic Islands, being similar to what has been being estimated for Spain as a whole. The objective included within the Polio Eradication Plan is accomplished, very little information being gathered from the public sector.