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Your search keyword '"Ishihara, Takuma"' showing total 523 results
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523 results on '"Ishihara, Takuma"'

9. Nomogram Predicting Locally Advanced Prostate Cancer in Patients with Clinically Organ-Confined Disease Who Underwent Robot-Assisted Radical Prostatectomy: A Retrospective Multicenter Cohort Study in Japan (The MSUG94 Group)

Author

Kawase, Makoto, Goto, Takayuki, Ebara, Shin, Tatenuma, Tomoyuki, Sasaki, Takeshi, Ishihara, Takuma, Ikehata, Yoshinori, Nakayama, Akinori, Toide, Masahiro, Yoneda, Tatsuaki, Sakaguchi, Kazushige, Teishima, Jun, Kobayashi, Takashi, Makiyama, Kazuhide, Inoue, Takahiro, Kitamura, Hiroshi, Saito, Kazutaka, Koga, Fumitaka, Urakami, Shinji, and Koie, Takuya

Published
2023
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10. Mirtazapine plus granisetron and dexamethasone for carboplatin-induced nausea and vomiting in patients with thoracic cancers: A prospective multicenter phase II trial

Author

Iihara, Hirotoshi, Iwai, Masamichi, Morita, Ryo, Fujita, Yukiyoshi, Ohgino, Keiko, Ishihara, Takuma, Hirose, Chiemi, Suzuki, Yasuyuki, Masubuchi, Ken, Kawazoe, Hitoshi, Kawae, Daisuke, Aihara, Kanako, Endo, Satoshi, Fukunaga, Koichi, Yamazaki, Mizuki, Tamura, Takuya, Kitamura, Yu, Fukui, Shin, Endo, Junki, and Suzuki, Akio

Published
2024
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11. Correction: Short-term outcomes associated with the use of a new powered circular stapler for rectal reconstructions: a retrospective study comparing it to manual circular staplers using inverse probability of treatment weight analysis

Author

Matsuhashi, Nobuhisa, Tajima, Jesse Yu, Yokoi, Ryoma, Kiyama, Shigeru, Endo, Masahide, Sato, Yuta, Kuno, Masashi, Hayashi, Hirokatsu, Asai, Ryuichi, Fukada, Masahiro, Yasufuku, Itaru, Tanaka, Yoshihiro, Okumura, Naoki, Murase, Katsutoshi, Ishihara, Takuma, and Takahashi, Takao

Published
2023
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13. Short-term outcomes associated with the use of a new powered circular stapler for rectal reconstructions: a retrospective study comparing it to manual circular staplers using inverse probability of treatment weight analysis

Author

Matsuhashi, Nobuhisa, Tajima, Jesse Yu, Yokoi, Ryoma, Kiyama, Shigeru, Endo, Masahide, Sato, Yuta, Kuno, Masashi, Hayashi, Hirokatsu, Asai, Ryuichi, Fukada, Masahiro, Yasufuku, Itaru, Tanaka, Yoshihiro, Okumura, Naoki, Murase, Katsutoshi, Ishihara, Takuma, and Takahashi, Takao

Published
2023
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14. Investigation of the relationship between intradialytic hypotension during hemodialysis and serum syndecan-1 concentration

Author

Oiwa, Hideaki, Okada, Hideshi, Suzuki, Keiko, Sumi, Kazuyuki, Yoshida, Shozo, Suzuki, Kodai, Ishihara, Takuma, Kitagaki, Hiroki, Kimura, Kaori, Naito, Yoshihito, Chiba, Naokazu, Kuroda, Ayumi, Uchida, Akihiro, Fukuda, Hirotsugu, Kawasaki, Yuki, Minamiyama, Toru, Nishio, Ayane, Shimada, Takuto, Kamidani, Ryo, Miura, Tomotaka, Tochibora, Ryota, Yamamoto, Saori, Kinomura, Yujiro, Kitagawa, Yuichiro, Fukuta, Tetsuya, Miyake, Takahito, Yoshida, Takahiro, Suzuki, Akio, Tetsuka, Nobuyuki, Tomita, Hiroyuki, Nawa, Takahide, and Ogura, Shinji

Published
2023
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16. Impact of augmented renal clearance on anticoagulant therapy in critically ill patients with coronavirus disease 2019: A retrospective cohort study

Author

Kamidani, Ryo, Okada, Hideshi, Kawasaki, Yuki, Shimada, Takuto, Tamaoki, Yuto, Nakashima, Yusuke, Nishio, Ayane, Fukuda, Hirotsugu, Minamiyama, Toru, Yoshida, Tomoki, Yoshimura, Genki, Miura, Tomotaka, Ishihara, Takuma, Fukuta, Tetsuya, Kitagawa, Yuichiro, Suzuki, Kodai, Miyake, Takahito, Doi, Tomoaki, Yoshida, Takahiro, Tetsuka, Nobuyuki, Yoshida, Shozo, and Ogura, Shinji

Published
2024
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17. Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy

Author

Taniguchi-Ikeda, Mariko, Koyanagi-Aoi, Michiyo, Maruyama, Tatsuo, Takaori, Toru, Hosoya, Akiko, Tezuka, Hiroyuki, Nagase, Shotaro, Ishihara, Takuma, Kadoshima, Taisuke, Muguruma, Keiko, Ishigaki, Keiko, Sakurai, Hidetoshi, Mizoguchi, Akira, Novitch, Bennett G, Toda, Tatsushi, Watanabe, Momoko, and Aoi, Takashi

Subjects
Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Muscular Dystrophy, Neurosciences, Stem Cell Research - Nonembryonic - Non-Human, Rare Diseases, Pediatric, Stem Cell Research - Induced Pluripotent Stem Cell, Intellectual and Developmental Disabilities (IDD), Stem Cell Research, Brain Disorders, Neurological, Neuroscience, Pathophysiology, Tissue Engineering
Abstract

Fukuyama congenital muscular dystrophy (FCMD) is a severe, intractable genetic disease that affects the skeletal muscle, eyes, and brain and is attributed to a defect in alpha dystroglycan (αDG) O-mannosyl glycosylation. We previously established disease models of FCMD; however, they did not fully recapitulate the phenotypes observed in human patients. In this study, we generated induced pluripotent stem cells (iPSCs) from a human FCMD patient and differentiated these cells into three-dimensional brain organoids and skeletal muscle. The brain organoids successfully mimicked patient phenotypes not reliably reproduced by existing models, including decreased αDG glycosylation and abnormal radial glial (RG) fiber migration. The basic polycyclic compound Mannan-007 (Mn007) restored αDG glycosylation in the brain and muscle models tested and partially rescued the abnormal RG fiber migration observed in cortical organoids. Therefore, our study underscores the importance of αDG O-mannosyl glycans for normal RG fiber architecture and proper neuronal migration in corticogenesis.

Published
2021

22. ASO Visual Abstract: Nomogram Predicting Locally Advanced Prostate Cancer in Patients with Clinically Organ-Confined Disease Who Underwent Robot-Assisted Radical Prostatectomy—A Retrospective Multicenter Cohort Study in Japan (the MSUG94 Group)

Author

Kawase, Makoto, Goto, Takayuki, Ebara, Shin, Tatenuma, Tomoyuki, Sasaki, Takeshi, Ishihara, Takuma, Ikehata, Yoshinori, Nakayama, Akinori, Toide, Masahiro, Yoneda, Tatsuaki, Sakaguchi, Kazushige, Teishima, Jun, Kobayashi, Takashi, Makiyama, Kazuhide, Inoue, Takahiro, Kitamura, Hiroshi, Saito, Kazutaka, Koga, Fumitaka, Urakami, Shinji, and Koie, Takuya

Published
2023
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25. Clinical characteristics and genome epidemiology of Stenotrophomonas maltophilia in Japan

Author

Hase, Ryota, primary, Sakurai, Aki, additional, Suzuki, Masahiro, additional, Itoh, Naoya, additional, Hayakawa, Kayoko, additional, Uemura, Kohei, additional, Matsumura, Yasufumi, additional, Kato, Hideaki, additional, Ishihara, Takuma, additional, van Duin, David, additional, Ohmagari, Norio, additional, Doi, Yohei, additional, and Saito, Sho, additional

Published
2024
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27. MP52-04 NOMOGRAM PREDICTING LOCALLY ADVANCED PROSTATE CANCER IN PATIENTS WITH CLINICALLY ORGAN-CONFINED DISEASE WHO UNDERWENT ROBOT-ASSISTED RADICAL PROSTATECTOMY: A RETROSPECTIVE MULTICENTER COHORT STUDY IN JAPAN (THE MSUG94 GROUP)

Author

Kawase, Makoto, primary, Goto, Takayuki, additional, Ebara, Shin, additional, Tatenuma, Tomoyuki, additional, Sasaki, Takeshi, additional, Ishihara, Takuma, additional, Ikehata, Yoshinori, additional, Nakayama, Akinori, additional, Toide, Masahiro, additional, Yoneda, Tatsuaki, additional, Sakaguchi, Kazushige, additional, Teishima, Jun, additional, Kobayashi, Takashi, additional, Makiyama, Kazuhide, additional, Inoue, Takahiro, additional, Kitamura, Hiroshi, additional, Saito, Kazutaka, additional, Koga, Fumitaka, additional, Urakami, Shinji, additional, and Koie, Takuya, additional

Published
2024
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35. Impact of Autophagy on Prognosis of Patients With Dilated Cardiomyopathy

Author

Kanamori, Hiromitsu, Yoshida, Akihiro, Naruse, Genki, Endo, Susumu, Minatoguchi, Shingo, Watanabe, Takatomo, Kawaguchi, Tomonori, Tanaka, Toshiki, Yamada, Yoshihisa, Takasugi, Nobuhiro, Ishihara, Takuma, Mikami, Atsushi, Miyazaki, Nagisa, Nishigaki, Kazuhiko, Minatoguchi, Shinya, Miyazaki, Tatsuhiko, and Okura, Hiroyuki

Published
2022
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37. Sarcopenia as a predictor of mortality in kidney transplant recipients: A 5‐year prospective cohort study with propensity score matching.

Author

Kosoku, Akihiro, Iwai, Tomoaki, Kabei, Kazuya, Nishide, Shunji, Machida, Yuichi, Ishihara, Takuma, and Uchida, Junji

Subjects
PROPORTIONAL hazards models, PROPENSITY score matching, SARCOPENIA, OVERALL survival, KIDNEY transplantation
Abstract

Background: Sarcopenia is known to bring about adverse outcomes in elderly populations and dialysis patients. However, whether it is a risk factor in kidney transplant recipients (KTRs) has not yet been established. In the present study, the association of sarcopenia with mortality was investigated in KTRs. Methods: We conducted a single‐center prospective cohort study and recruited KTRs who were more than 1‐year posttransplant from August 2017 to January 2018. The participants were followed for 5 years, and the Kaplan–Meier method and Cox proportional hazards model were used to assess patient survival. Results: A total of 212 KTRs with a median age of 54 years and median transplant vintage of 79 months were enrolled in this study. Among them, 33 (16%) had sarcopenia according to the Asia Working Group for Sarcopenia 2019 at baseline. During the 5‐year follow‐up period, 20 (9.4%) died, 5 returned to dialysis after graft loss, and 4 were lost to follow‐up. The 5‐year overall survival rate was 90%. After 1:1 propensity score matching, a matched cohort with 60 KTRs was generated. The overall survival rate was significantly lower in the sarcopenia group compared to the non‐sarcopenia group (p = 0.025, log‐rank test). Furthermore, mortality risk was significantly higher in the sarcopenia group compared to the non‐sarcopenia group (hazard ratio = 7.57, 95% confidence interval = 0.94–62). Conclusion: Sarcopenia was a predictor of mortality in KTRs. KTRs with suboptimal muscle status who were at risk for poor survival could have a clinical benefit by interventions for sarcopenia. [ABSTRACT FROM AUTHOR]

Published
2024
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38. FDG uptake in the cervical muscles after neck dissection: imaging features and postoperative natural course on 18F‑FDG‑PET/CT.

Author

Iritani, Yukako, Kato, Hiroki, Kaneko, Yo, Ishihara, Takuma, Ando, Tomohiro, Kawaguchi, Masaya, Shibata, Hirofumi, Ogawa, Takenori, Noda, Yoshifumi, Hyodo, Fuminori, and Matsuo, Masayuki

Abstract

Purpose: This study aimed to assess the imaging features and postoperative natural course of 18F-fluorodeoxyglucose (FDG) uptake in the cervical muscles after neck dissection. Materials and methods: This study included 83 patients who underwent preoperative and postoperative 18F-FDG-PET/CT and were diagnosed with head and neck malignancy after neck dissection. Postoperative 18F-FDG-PET/CT was performed within 5 years after neck dissection. Preoperative and postoperative FDG uptake of the trapezius, sternocleidomastoid, scalene, pectoralis major, and deltoid muscles was visually assessed. Increased postoperative uptake was visually defined as higher postoperative FDG uptake than the preoperative one in the corresponding muscle. The maximum standardized uptake value (SUVmax) was measured in cases with increased postoperative uptakes. Results: Increased postoperative uptakes were observed in 43 patients (52%). The trapezius (31/83, 37%), sternocleidomastoid (19/83, 23%), and scalene (12/83, 14%) muscles were involved, as opposed to the pectoralis major and deltoid muscles were not. Increased postoperative uptakes were observed on the dissected side in all 43 patients. Significant differences between SUVmax estimated from the mixed-effects model and postoperative months were observed in the trapezius muscle (Coefficient (β) = −0.038; 95% confidence interval (CI): [−0.047, −0.028]; p < 0.001) and sternocleidomastoid muscle (β = −0.015; 95% CI: [−0.029, −0.001]; p = 0.046). Conclusions: Increased postoperative uptakes in the cervical muscles were observed on the dissected side in approximately half of the patients after neck dissection. The SUVmax in the trapezius and sternocleidomastoid muscles decreased after surgery over time. [ABSTRACT FROM AUTHOR]

Published
2024
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45. Assessment of Arterial Involvement in Pancreatic Cancer: Utility of Reconstructed CT Images Perpendicular to Artery.

Author

Noda, Yoshifumi, Kobayashi, Kazuhiro, Kawaguchi, Masaya, Ando, Tomohiro, Takai, Yukiko, Suto, Taketo, Iritani, Yukako, Ishihara, Takuma, Fukada, Masahiro, Murase, Katsutoshi, Kawai, Nobuyuki, Kaga, Tetsuro, Miyoshi, Toshiharu, Hyodo, Fuminori, Kato, Hiroki, Miyazaki, Tatsuhiko, Matsuhashi, Nobuhisa, Yoshida, Kazuhiro, and Matsuo, Masayuki

Subjects
ARTERIOGRAPHY, DIAGNOSTIC imaging, COMPUTED tomography, RETROSPECTIVE studies, DESCRIPTIVE statistics, PANCREATIC tumors, COMPUTER-aided diagnosis, MEDICAL records, ACQUISITION of data, PANCREATECTOMY, DIGITAL image processing, CONFIDENCE intervals, CONTRAST media, SPLENIC artery
Abstract

Simple Summary: The diagnostic performance and interobserver variability of the contrast-enhanced CT currently used for evaluating arterial involvement from pancreatic cancer has limitations. The purpose of this study was to investigate the utility of reconstructed CT images perpendicular to the artery for assessing arterial involvement from pancreatic cancer and to compare the interobserver variability between it and the current diagnostic imaging method. We found that reconstructed CT images perpendicular to the splenic artery were feasible and showed less interobserver variability than current diagnostic method images. The purpose of this study was to investigate the utility of reconstructed CT images perpendicular to the artery for assessing arterial involvement from pancreatic cancer and compare the interobserver variability between it and the current diagnostic imaging method. This retrospective study included patients with pancreatic cancer in the pancreatic body or tail who underwent preoperative pancreatic protocol CT and distal pancreatectomy. Five radiologists used axial and coronal CT images (current method) and perpendicular reconstructed CT images (proposed method) to determine if the degree of solid soft-tissue contact with the splenic artery was ≤180° or >180°. The generalized estimating equations were used to compare the diagnostic performance of solid soft-tissue contact >180° between the current and proposed methods. Fleiss' ĸ statistics were used to assess interobserver variability. The sensitivity and negative predictive value for diagnosing solid soft-tissue contact >180° were higher (p < 0.001 for each) and the specificity (p = 0.003) and positive predictive value (p = 0.003) were lower in the proposed method than the current method. Interobserver variability was improved in the proposed method compared with the current method (ĸ = 0.87 vs. 0.67). Reconstructed CT images perpendicular to the artery showed higher sensitivity and negative predictive value for diagnosing solid soft-tissue contact >180° than the current method and demonstrated improved interobserver variability. [ABSTRACT FROM AUTHOR]

Published
2024
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47. A short decision time for transcatheter embolization can better associate mortality in patients with pelvic fracture: a retrospective study

Author

Mizuno, Yosuke, primary, Miyake, Takahito, additional, Okada, Hideshi, additional, Ishihara, Takuma, additional, Kanda, Norihide, additional, Ichihashi, Masahiro, additional, Kamidani, Ryo, additional, Fukuta, Tetsuya, additional, Yoshida, Takahiro, additional, Nagata, Shoma, additional, Kawada, Hiroshi, additional, Matsuo, Masayuki, additional, Yoshida, Shozo, additional, and Ogura, Shinji, additional

Published
2024
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49. Proposal for Classifying the Emetogenicity of Oral Anticancer Agents with a Focus on PARP Inhibitors: A Prospective, Observational, Multicenter Study (JASCC-CINV 2002)

Author

Yamamoto, Senri, primary, Tsuchiya, Masami, additional, Iihara, Hirotoshi, additional, Hayasaki, Yoh, additional, Hori, Kyoko, additional, Kumakura, Yasuo, additional, Watanabe, Daichi, additional, Sakai, Hideki, additional, Nakagawa, Satoshi, additional, Kudoh, Akiko, additional, Oishi, Hajime, additional, Kado, Nobuhiro, additional, Go, Makiko, additional, Mashima, Kota, additional, Uchida, Takashi, additional, Yasue, Moeka, additional, Maeda, Akimitsu, additional, Nishino, Kimihiro, additional, Matsumoto, Koji, additional, Sato, Shinya, additional, Ueda, Yutaka, additional, Tomio, Kensuke, additional, Hayashi, Katsuhisa, additional, Takenaka, Motoki, additional, Mori, Masahiko, additional, Kajiyama, Hiroaki, additional, Bomoto, Yoshimasa, additional, Suzuki, Shiro, additional, Ishihara, Takuma, additional, Suzuki, Akio, additional, and Abe, Masakazu, additional

Published
2024
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