1. An Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder
- Author
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Rahaman, Md. Ashiquir, Lopa, Maksuda, Uddin, K. M. Furkan, Baqui, Md. Abdul, Keya, Selina Parvin, Faruk, Md. Omar, Sarker, Shaoli, Basiruzzaman, Mohamm, Islam, Mazharul, AlBanna, Ammar, Jahan, Nargis, Chowdhury, M. A. K. Azad, Saha, Narayan, Hussain, Manzoor, Colombi, Costanza, O'Rielly, Darren, Woodbury-Smith, Marc, Ghaziuddin, Mohammad, Rahman, Mohammad Mizanur, and Uddin, Mohamm
- Abstract
This study explored the physical and clinical phenotype of Bangladeshi children with autism spectrum disorder (ASD). A totally of 283 children who were referred for screening and administered Module 1 of the Autism Diagnostic Observation Schedule (ADOS) were included. Overall, 209 met the ADOS algorithmic cutoff for ASD. A trend for greater weight and head circumference was observed in children with ASD versus non-ASD. Head circumference was significantly (p < 0.03) larger in ASD males compared with non-ASD males. A trend was also observed for symptom severity, higher in females than males (p = 0.068), with further analyses demonstrating that social reciprocity (p < 0.014) and functional play (p < 0.03) were significantly more impaired in ASD females than males. The findings help understand sex differences in ASD.
- Published
- 2021
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