1. Enoxacin in the therapy of anal and pharyngeal gonococcal infections
- Author
-
Jean Draker, Jean S. Hardy, Mary S. Rafter, and Barbara Romanowski
- Subjects
Microbiology (medical) ,Adult ,Enoxacin ,Male ,medicine.medical_specialty ,Adolescent ,medicine.drug_class ,Microgram ,Antibiotics ,Gonorrhea ,Administration, Oral ,Dermatology ,medicine.disease_cause ,Gastroenterology ,Double-Blind Method ,Internal medicine ,medicine ,Humans ,Proctitis ,Randomized Controlled Trials as Topic ,Dose-Response Relationship, Drug ,business.industry ,Pharynx ,Public Health, Environmental and Occupational Health ,Pharyngitis ,Anal Infection ,Anus ,medicine.disease ,Infectious Diseases ,medicine.anatomical_structure ,Immunology ,Neisseria gonorrhoeae ,Female ,business ,medicine.drug - Abstract
In this randomized double-blind study, 51 patients with uncomplicated anal or pharyngeal Neisseria gonorrhoeae infection were evaluated to determine the efficacy and safety of 200- or 400-mg of enoxacin twice a day for two days. Enoxacin cured all anal infections and 12 out of 13 pharyngeal infections. All 82 isolates of N. gonorrhoeae tested were inhibited by 1 microgram of enoxacin/ml.
- Published
- 1989