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1. Clinical Meaningfulness in Alzheimer’s Disease Clinical Trials. A Report from the EU-US CTAD Task Force

3. Acceptable performance of blood biomarker tests of amyloid pathology — recommendations from the Global CEO Initiative on Alzheimer’s Disease

7. Neuropsychiatric Symptoms in AD: Clinical Trials Targeting Mild Behavioral Impairment: A Report from the International CTAD Task Force

9. Features and perceptions of a critical care outreach physician role

13. Can We Use Blood Biomarkers as Entry Criteria and for Monitoring Drug Treatment Effects in Clinical Trials? A Report from the EU/US CTAD Task Force

15. Low tidal volume ventilation for patients undergoing laparoscopic surgery: a secondary analysis of a randomised clinical trial

30. Potential role for extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) during in-hospital cardiac arrest in Australia: A nested cohort study

34. Contributors

38. Listen to me, I really am sick! Patient and family narratives of clinical deterioration before and during rapid response system intervention.

39. Frequency and potential causes of non‐beneficial Code Blue activations at a metropolitan teaching hospital.

40. Acknowledgement and use of advance care directives and goals of care by emergency department staff: a mixed method post intervention study.

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