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Objective: Recurrent aphthous stomatitis (RAS) is a chronic inflammatory disease of oral mucosa characterized by recurrent painful ulcers. Despite it is a condition seen frequently, its etiology and pathogenesis are not known fully. Its etiology is reportedly idiopathic or multifactorial. Mean platelet volume (MPV) indicates thrombocytic activation, while neutrophil/lymphocyte rate (NLR) is an indicator of chronic inflammation, and both of them can be measured during routine whole blood analysis. The aim of this study is to investigate MPV and NLR values in patients with RAS and the controlgroup.Methods: A total of 39 patients with RAS and 34 control subjects were included in the study.Results: When the patient and the control groups were compared, MPV, ESR, CRP and vitamin B12 values were significantly higher in the patient group while NLR, WBC, hemoglobin, neutrophil and lymphocyte values were not significantly different between both groups.Conclusion: It was shown that MPV can be used as a diagnostic indicator in patients with RAS.

Septum deviasyonu kulak burun boğaz kliniklerinde en sık karşılaşılan, prevalansı erişkin toplumda yüksek olan bir nazal patolojidir. Septum deviasyonunun da etyolojisinde yer aldığı OUAS gibi komorbiditesi yüksek olan hastalıkların atriyal fibrilasyon gibi subklinik kardiyak patolojilere neden olduğu bilinmektedir. Bu çalışmada nazal septum deviasyonu olan ve başka nazal patolojisi olmayan hastalar, nazal patolojisi olmayan sağlıklı deneklerle karşılaştırıldı. Çalışmamızdaki hasta grubu ve kontrol grubu arasında visüel analog skala(VAS), rinomanometri, ekokardiyografi ve yüzeyel elektrografi uygulandı ve sonuçlar karşılaştırıldı. Hasta grubunda kontrol grubuna göre, VAS ve transnazal basınç anlamlı yüksek bulunurken transnazal akım anlamlı düşük bulundu. Hasta grubunda interatriyal ve intraatriyal iletinin uzadığını gösteren PA septum, PA triküspit, PA lateral-triküspit, PA septum-triküspit değerleri kontrol grubuna göre anlamlı yüksek bulundu. Hasta grubunda sol atriyum boyutunu gösteren, sol atriyum genişliği (LA), sol atriyum hacimlerinden LA volüm maksimum, LA volüm minimum ve LA volüm p değerleri kontrol grubuna göre anlamlı yüksek bulundu. Çalışmamızın sonucunda elde ettiğimiz mevcut veriler ile nazal septum deviasyonunun atriyal fibrilasyona yatkınlık oluşturan subklinik kardiyak patolojilere neden olabileceğini ve bu patolojilerin ekokardiyografi gibi noninvaziv yöntemlerle saptanabileceğini göstermiş olduk. Anahtar kelimeler: Nazal septum deviasyonu, atriyal fibrilasyon, ekokardiyografi, rinomanometri Nasal septum deviation is one of the most frequently encountered nasal pathology in ear nose throat clinics with a high prevelance among the adult population. Diseas with a high comorbidity such as Obstructive Sleep Apnea Syndrome(OSAS), among whose etiology septum deviation takes place, can cause subclinical patologies like atrial fibrilation.In this study, patients who have nasal septum deviation and who do not have other forms of nasal pathologies, are compared with other healthy patients who do not have any nasal pathologies.In the study, the patient and the control group are subjected to visual anologue scale (VAS), rhinomanometry, echocardiography and surface electrocardiography and the results are compared between two groups. In the patient group while the VAS and transnasal pressure were found meaningful higher, the transnasal flow was found meaningful lower than the control group. In the patient group PA septum, PA tricuspide, PA lateral-tricuspide, PA septum-tricuspide values, which domanstrate that interatrial and intraatrial conduction prolonged, were found meningful higher than the control group. In the patient group left atrium width (LA), LA volume maximum, LA volume minimum and LA volume p values, which show the size of left atrium, were found meningful high in comparison to the control group.As a result of the data obtained from this study, the dissertation domanstrates that nasal septumdeviation can cause subclinical cardiac pathologies such as atrial fibrilation and these pathologies can be detected with noninvasive methods such as echocardiography.Keywords: Nasal septum deviation, atrial fibrilation, echocardiography, rhinomanometry. 73

WOS:000348654600016 PubMed: 25667794 Background: Cervicofacial emphysema may arise due to the leakage of air from a defect in the aerodigestive tract to the fascial layers of neck and face. Rarely, it may be caused by insufflation of air through the Stensen's duct. Case Report: We present a case with diffuse facial, cervical and mediastinal emphysema due to playing a wind instrument immediately after a facial trauma. There was no mucosal defect or laceration noticed by examination which could explain the origin of the emphysema. Despite the widespread cervicofacial emphysema with mediastinal involvement, the patient significantly improved within 48 hours without any intervention. Conclusion: Even though cervicofacial emphysema ameliorates spontaneously, increased care must be taken, especially when there is pneumomediastinum and/or pneumothorax.

Amaç: Rekürren aftöz stomatit (RAS) oral mukozanın tekrarlayan,ağrılı ülserlerle karakterize, kronik inflamatuar bir hastalığıdır. Sıkgörülen bir durum olmasına karşın etyolojisi ve patogenezi tam olarak bilinmemektedir. Etyolojisinin idiyopatik veya multifaktöryel olduğu belirtilmektedir. Ortalama trombosit hacmi (MPV) trombositaktivasyonunu gösteren, nötrofil lenfosit oranı (NLR) ise kronik inflamasyon göstergesi olan ve her ikisi de rutin tam kan tetkiklerindeölçülebilen değerlerdir. Bu çalışmanın amacı RAS'lı ve kontrol grubuhastalardaki MPV ve NLR değerlerini araştırmaktır. Yöntem:Bu çalışmaya 39 RAS'ı bulunan ve 34 kontrol grubu hastadahil edildi. Bulgular:Hasta ve kontrol grubu karşılaştırıldığında MPV, ESR, CRP,vitamin B12 değerlerinin hasta grubunda kontrol grubuna göre anlamlı derecede yüksek çıktı ve NLR, WBC, hemoglobin, nötrofil, lenfositdeğerleri arasında her iki grup arasında anlamlı fark bulunmadı. Sonuç:Ortalama trombosit hacminin, RAS'lı hastalarda tanısal birgösterge olabileceği ortaya konuldu Objective:Recurrent aphthous stomatitis (RAS) is a chronic inflammatory disease of oral mucosa characterized by recurrent painfululcers. Despite it is a condition seen frequently, its etiology andpathogenesis are not known fully. Its etiology is reportedly idiopathic or multifactorial. Mean platelet volume (MPV) indicates thrombocytic activation, while neutrophil/lymphocyte rate (NLR) is an indicator of chronic inflammation, and both of them can be measuredduring routine whole blood analysis. The aim of this study is to investigate MPV and NLR values in patients with RAS and the controlgroup. Methods:A total of 39 patients with RAS and 34 control subjectswere included in the study. Results: When the patient and the control groups were compared,MPV, ESR, CRP and vitamin B12 values were significantly higher inthe patient group while NLR, WBC, hemoglobin, neutrophil and lymphocyte values were not significantly different between both groups. Conclusion:It was shown that MPV can be used as a diagnostic indicator in patients with RAS