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The article discusses the importance of dispersion and scintillation in radio astronomy. It explains how dispersion can be used to understand the geography of the galaxy and signals from distant galaxies by analyzing the wavelength dependence of the dispersion measure. The article also mentions that dispersion played a role in determining that fast radio bursts originated from beyond the Milky Way. Additionally, it highlights the role of dispersion and scintillation in answering questions about dark matter and mapping out the invisible matter in the universe. The article also briefly mentions the variability in light of Mira Ceti and the temperature of sunspots. [Extracted from the article]

Landscape features, such as hedgerows, can play a role in enhancing terrestrial carbon (C) sinks, especially in North-western Europe, where they form a large part of the agricultural landscape. To date, there are few studies relating aerial imagery to ground-truthed biomass measurements and relating changes in biomass to hedgerow management. This study sought to develop relationships between measured biomass of hedgerows and digital elevation model (DEM) data from drones and aircraft. Furthermore, changes in hedgerow above-ground and below-ground biomass stocks were assessed using a systematic grid sample, DEM data and developed volume-biomass regression models. The developed inventory framework was then applied to a pilot study area of 419,701 ha in Ireland. Robust relationships were developed relating DEM data to volume and above-ground biomass. Model equations were also developed linking above-ground and below-ground biomass. However, these were less robust due to the confounding impacts of hedgerow management intensity, hedgerow type and dominant species. Above-ground biomass density was linearly correlated with hedge volume. Wider, less intensively managed, irregular hedges exhibit a higher biomass stocks per km, when compared to regular, more intensively managed hedgerows. When the models were extrapolated to the county level, hedgerow biomass C pools for Co Wexford and Waterford are suggested to be a net emission of -0.3 tC ha -1 year -1 due to hedgerow removals and management. Flailing or coppicing of hedgerows, in particular irregular profile hedgerows, had the largest impact on the biomass C balance in the pilot study area. Re-introduction of traditional management practices such as layering and increasing the allowable hedgerow width in areas qualifying for farm payments could be considered with the aim of increasing the maximum sink potential of established hedgerows., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier B.V. All rights reserved.)

Metabotropic glutamate receptor 5 (mGluR5) can modulate synaptic transmission by increasing intracellular Ca2+ and it plays a role in several forms of synaptic plasticity. We have constructed a fusion of human mGluR5 and green fluorescent protein (mGluR5-GFP). Expression of mGluR5-GFP in clonal cell lines yielded a functional fluorescent receptor with pharmacological profiles similar to wild-type mGluR5. mGluR5-GFP coimmunoprecipitated with Homer-1c, indicating that addition of GFP to the C-terminal did not prevent Homer binding. Coexpression of wild-type mGluR5 or mGluR5-GFP with Homer 1c, but not Homer-1a, resulted in reduced receptor surface localization and the formation of intracellular clusters. Neither Homer-1a nor Homer-1c had any effect on mGluR1 or mGluR1-GFP distribution. mGluR5-GFP expressed alone or in combination with Homer-1a formed dimers in HEK cells. Coexpression with Homer-1c, however, prevented mGluR5-GFP dimerization. Neither Homer altered the agonist profiles of mGluR5 or mGluR5-GFP. These data indicate that the functional expression of mGluR5 is regulated by Homer-1c and demonstrate that mGluR5-GFP provides a useful tool to study the molecular pharmacology and cell biology of mGluRs in real-time., (Copyright 2001 Academic Press.)