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1. Reducing the Gap in Neurosurgical Education in LMICs: A Report of a Non-Profit Educational Program

Author

Menna, Grazia, Kolias, Angelos, Esene, Ignatius N., Barthélemy, Ernest J., Hoz, Samer, Laeke, Tsegazeab, Veiga Silva, Ana Cristina, Longo-Calderón, Gabriel Mauricio, Baticulon, Ronnie E., Zabala, Joaquín Pérez, Hassani, Fahd Derkaoui, El Abbadi, Naija, Khan, Muhammad Mukhtar, Robertson, Faith C., Thango, Nqobile, Cheresem, Beverly, Ogando-Rivas, Elizabeth, Roumy, Louis-Georges, Karekezi, Claire, Alamri, Alexander, Spena, Giannantonio, Cenzato, Marco, Servadei, Franco, Giussani, Carlo Giorgio, and Nicolosi, Federico

Published
2024
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2. Casemix, management, and mortality of patients receiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort study

Author

Abbas, Ghayur, Abdallah, Omar Ibrahim, Abdel-Lateef, Ahmed, Abdifatah, Khalif, Abdullateef, Awfa, Abeygunaratne, Ruvini, Aboellil, Mostafa, Adam, Abass, Adams, Robert, Adeleye, Amos, Adeolu, Augustine, Adji, Novan Krisno, Afianti, Nur, Agarwal, Sudarsan, Aghadi, Ifeanyi Kene, Aguilar, Paúl Martín Méndez, Ahmad, Syeda Rida, Ahmed, Daniyal, Ahmed, Nafees, Aizaz, Haider, Aji, Yunus Kuntawi, Alamri, Alex, Alberto, Augusto Jacinto Mussindo, Alcocer, Luis Alcocer, Alfaro, Lesly Gonzales, Al-Habib, Amro, Alhourani, Ahmad, Ali, Syed Muhammad Rafay, Alkherayf, Fahad, AlMenabbawy, Ahmed, Alshareef, Aliyah, Aminullah, Muhammad Adil s/o, Amjad, Madeha, Amorim, Robson Luis Oliveira de, Anbazhagan, Sathiaprabhu, Andrade, Almir, Antar, Waleed, Anyomih, Theophilus T.K., Aoun, Salah, Apriawan, Tedy, Armocida, Daniele, Arnold, Paul, Arraez, Miguel, Assefa, Temesgen, Asser, Andres, Athiththan, S.P., Attanayake, Deepal, Aung, Maung Maung, Avi, Allan, Ayala, Victor Enrique Antolinez, Azab, Mohammed, Azam, Gaousul, Azharuddin, Mohd, Badejo, Olukemi, Badran, Mohamed, Baig, Azam Ali, Baig, Rehman Ali, Bajaj, Ankur, Baker, Paul, Bala, Renu, Balasa, Artur, Balchin, Ross, Balogun, James, Ban, Vin Shen, Bandi, Bharath Kumar Reddy, Bandyopadhyay, Soham, Bank, Matthew, Barthelemy, Ernest, Bashir, Mohammed Talha, Basso, Luciano Silveira, Basu, Surajit, Batista, Auricelio, Bauer, Marlies, Bavishi, Devi, Beane, Abi, Bejell, Shmuel, Belachew, Anteneh, Belli, Antonio, Belouaer, Amani, Bendahane, Najia El Abbadi, Benjamin, Okanga, Benslimane, Youssef, Benyaiche, Chaymae, Bernucci, Claudio, Berra, Luigi Valentino, Bhebe, Arnold, Bimpis, Alexios, Blanaru, Diana, Bonfim, Jean Claude, Borba, Luis A B, Borcek, Alp Ozgun, Borotto, Erika, Bouhuwaish, Ahmad Elmabri Mohammad, Bourilhon, Facundo, Brachini, Gioia, Breedon, Joshua, Broger, Maximilian, Brunetto, Giacoma Maria Floriana, Bruzzaniti, Placido, Budohoska, Natalia, Burhan, Hira, Calatroni, Maximiliano Luis, Camargo, Catherine, Cappai, Pier Francesco, Cardali, Salvatore Massimiliano, Castaño-Leon, Ana M, Cederberg, David, Celaya, Mikel, Cenzato, Marco, Challa, Lakshmi Madhavi, Charest, Dhanny, Chaurasia, Bipin, Chenna, Rabah, Cherian, Iype, Ching'o, Juliana Henry, Chotai, Tejas, Choudhary, Ajay, Choudhary, Nabeel, Choumin, Florence, Cigic, Tomislav, Ciro, Juan, Conti, Carlo, Corrêa, Antônio Carlos de Souza, Cossu, Giulia, Couto, Maíra Piani, Cruz, Aurora, D'Silva, Divya, D'Aliberti, Giuseppe Antonio, Dampha, Lamin, Daniel, Roy Thomas, Dapaah, Andrew, Darbar, Aneela, Dascalu, Gabriel, Dauda, Happy Amos, Davies, Owain, Delgado-Babiano, Andrea, Dengl, Markus, Despotovic, Marko, Devi, Indira, Dias, Celeste, Dirar, Mohamed, Dissanayake, Melina, Djimbaye, Hananiah, Dockrell, Simon, Dolachee, Ali, Dolgopolova, Julija, Dolgun, Muge, Dow, Abdalrouf, Drusiani, Davide, Dugan, Artjom, Duong, Dinh Tuan, Duong, Trung Kien, Dziedzic, Tomasz, Ebrahim, Ali, El Fatemi, Nizar, El Helou, Antonios El, El Maaqili, Rachid El, El Mostarchid, Brahim El, El Ouahabi, Abdessamad El, Elbaroody, Mohammad, El-Fiki, Ahmed, El-Garci, Ahmed, El-Ghandour, Nasser M.F., Elhadi, Muhammed, Elleder, Vanessa, Elrais, Safa, El-shazly, Mohamed, Elshenawy, Mohamed, Elshitany, Hesham, El-Sobky, Omar, Emhamed, Marwa, Enicker, Basil, Erdogan, Onur, Ertl, Sebastian, Esene, Ignatius, Espinosa, Omar Ocampo, Fadalla, Tarig, Fadelalla, Mohammed, Faleiro, Rodrigo Moreira, Fatima, Nida, Fawaz, Charbel, Fentaw, Assefa, Fernandez, Carla Eiriz, Ferreira, Ana, Ferri, Francesco, Figaji, Tony, Filho, Emerson L B, Fin, Loic, Fisher, Benjamin, Fitra, Fitra, Flores, Alexis Palpan, Florian, Ioan Stefan, Fontana, Vincenzo, Ford, Lauren, Fountain, Daniel, Frade, Jose Maria Roda, Fratto, Antonio, Freyschlag, Christian, Gabin, Aranzazu Sánchez, Gallagher, Clare, Ganau, Mario, Gandia-Gonzalez, Maria Luisa, Garcia, Andoni, Garcia, Borja Hernandez, Garusinghe, Sanjeewa, Gebreegziabher, Biniam, Gelb, Adrian, George, Jerome St, Germanò, Antonino Francesco, Ghetti, Ilaria, Ghimire, Prajwal, Giammarusti, Alessandro, Gil, Jose Luis, Gkolia, Panagiota, Godebo, Yoseph, Gollapudi, Prakash Rao, Golubovic, Jagos, Gomes, Jeremias Fernando, Gonzales, Javier, Gormley, William, Gots, Alexander, Gribaudi, Giulia Letizia, Griswold, Dylan, Gritti, Paolo, Grobler, Ruan, Gunawan, Rudy, Hailemichael, Birhanu, Hakkou, Elmehdi, Haley, Mark, Hamdan, Alhafidz, Hammed, Ali, Hamouda, Waeel, Hamzah, Nurul Ashikin, Han, Nyein Latt, Hanalioglu, Sahin, Haniffa, Rashan, Hanko, Martin, Hanrahan, John, Hardcastle, Timothy, Hassani, Fahd Derkaoui, Heidecke, Volkmar, Helseth, Eirik, Hernández-Hernández, Miguel Ángel, Hickman, Zachary, Hoang, Le Minh Chau, Hollinger, Alexa, Horakova, Lenka, Hossain-Ibrahim, Kismet, Hou, Boru, Hoz, Samer, Hsu, Janine, Hunn, Martin, Hussain, Madiha, Iacopino, Giorgia, Ideta, Mylena Miki Lopes, Iglesias, Irene, Ilunga, Ali, Imtiaz, Nafiz, Islam, Rafiza, Ivashchenko, Serge, Izirouel, Karim, Jabal, Mohamed Sobhi, Jabal, Soubhi, Jabang, John Nute, Jamjoom, Aimun, Jan, Irfan, Jarju, Landing BM, Javed, Saad, Jelaca, Bojan, Jhawar, Sukhdeep Singh, Jiang, Ting Ting, Jimenez, Fernando, Jiris, Jorge, Jithoo, Ron, Johnson, Walt, Joseph, Mathew, Joshi, Rameshman, Junttila, Eija, Jusabani, Mubashir, Kache, Stephen Akau, Kadali, Satyavara Prasad, Kalkmann, Gabriela F, Kamboh, Usman, Kandel, Hitham, Karakus, Ahmet Kamil, Kassa, Mengistu, Katila, Ari, Kato, Yoko, Keba, Martin, Kehoe, Kristy, Kertmen, Huseyin Hayri, Khafaji, Soha, Khajanchi, Monty, Khan, Mohammed, Khan, Muhammad Mukhtar, Khan, Sohail Daud, Khizar, Ahtesham, Khriesh, Amir, Kierońska, Sara, Kisanga, Paul, Kivevele, Boniface, Koczyk, Kacper, Koerling, Anna-Lucia, Koffenberger, Danielle, Kõiv, Kennet, Kõiv, Leho, Kolarovszki, Branislav, König, Marton, Könü-Leblebicioglu, Dilek, Koppala, Santhoshi Devi, Korhonen, Tommi, Kostkiewicz, Boguslaw, Kostyra, Kacper, Kotakadira, Srinivas, Kotha, Arjun Reddy, Kottakki, Madhu Narayana Rao, Krajcinovic, Nenad, Krakowiak, Michal, Kramer, Andreas, Krishnamoorthy, Selvamuthukumaran, Kumar, Ashok, Kumar, Pankaj, Kumar, Pradhumna, Kumarasinghe, Nilaksha, Kuncha, Gowtham, Kutty, Raja K., Laeke, Tsegazeab, Lafta, Ghazwan, Lammy, Simon, Lapolla, Pierfrancesco, Lardani, Jacopo, Lasica, Nebojsa, Lastrucci, Giancarlo, Launey, Yoann, Lavalle, Laura, Lawrence, Tim, Lazaro, Albert, Lebed, Vitalii, Leinonen, Ville, Lemeri, Lawrence, Levi, Leon, Lim, Jia Yi, Lim, Xiao Yi, Linares-Torres, Jorge, Lippa, Laura, Lisboa, Lurdes, Liu, Jinfang, Liu, Ziyuan, Lo, William B, Lodin, Jan, Loi, Federico, Londono, Daniella, Lopez, Pedro Antonio Gomez, López, Cristina Barceló, Lotbiniere-Bassett, Madeleine De, Lulens, Rihards, Luna, Facundo Hector, Luoto, Teemu, M.V., Vijaya Sekhar, Mabovula, Ndyebo, MacAllister, Matthew, Macie, Alcina Americo, Maduri, Rodolfo, Mahfoud, Moufid, Mahmood, Ashraf, Mahmoud, Fathia, Mahoney, Dominic, Makhlouf, Wissam, Malcolm, George, Malomo, Adefolarin, Malomo, Toluyemi, Mani, Manoranjitha Kumari, Marçal, Tomás Gazzinelli, Marchello, Jacopo, Marchesini, Nicolò, Marhold, Franz, Marklund, Niklas, Martín-Láez, Rubén, Mathaneswaran, Vickneswaran, Mato-Mañas, David José, Maye, Helen, McLean, Aaron Lawson, McMahon, Catherine, Mediratta, Saniya, Mehboob, Mehreen, Meneses, Alisson, Mentri, Nesrine, Mersha, Hagos, Mesa, Ana Milena, Meyer, Cristy, Millward, Christopher, Mimbir, Salomao Amone, Mingoli, Andrea, Mishra, Parashruram, Mishra, Tejesh, Misra, Basant, Mittal, Siddharth, Mohammed, Imran, Moldovan, Ioana, Molefe, Masechaba, Moles, Alexis, Moodley, Preston, Morales, Mario Augusto Narváez, Morgan, Lucy, Morillo, German Del Castillo, Moustafa, Wahab, Moustakis, Nikolaos, Mrichi, Salma, Munjal, Satya Shiva, Muntaka, Abdul-Jalilu Mohammed, Naicker, Denver, Nakashima, Paulo E H, Nandigama, Pratap Kumar, Nash, Samantha, Negoi, Ionut, Negoita, Valetina, Neupane, Samundra, Nguyen, Manh Hung, Niantiarno, Fajar Herbowo, Noble, Abbi, Nor, Mohd Arman Muhamad, Nowak, Blazej, Oancea, Andrei, O'Brien, Frazer, Okere, Oghenekevwe, Olaya, Sandra, Oliveira, Leandro, Oliveira, Louise Makarem, Omar, Fatma, Ononeme, Okezi, Opšenák, René, Orlandini, Simone, Osama, Alrobah, Osei-Poku, Dorcas, Osman, Haytham, Otero, Alvaro, Ottenhausen, Malte, Otzri, Shuli, Outani, Oumaima, Owusu, Emmanuel Abem, Owusu-Agyemang, Kevin, Ozair, Ahmad, Ozoner, Baris, Paal, Elli, Paiva, Mauro Sérgio, Paiva, Wellingson, Pandey, Sharad, Pansini, Gastone, Pansini, Luigi, Pantel, Tobias, Pantelas, Nikolaos, Papadopoulos, Konstantinos, Papic, Vladimir, Park, Kee, Park, Nick, Paschoal, Eric Homero Albuquerque, Paschoalino, Mylla Christie de Oliveira, Pathi, Rajesh, Peethambaran, Anilkumar, Pereira, Thiago Andrade, Perez, Irene Panero, Pérez, Claudio José Piqueras, Periyasamy, Tamilanandh, Peron, Stefano, Phillips, Michael, Picazo, Sofía Sotos, Pinar, Ertugrul, Pinggera, Daniel, Piper, Rory, Pirakash, Pathmanesan, Popadic, Branko, Posti, Jussi P., Prabhakar, Rajmohan Bhanu, Pradeepan, Sivanesalingam, Prasad, Manjunath, Prieto, Paola Calvachi, Prince, Ron, Prontera, Andrea, Provaznikova, Eva, Quadros, Danilo, Quintero, Nezly Jadid Romero, Qureshi, Mahmood, Rabiel, Happiness, Rada, Gabriel, Ragavan, Sivagnanam, Rahman, Jueria, Ramadhan, Omar, Ramaswamy, Padma, Rashid, Sakina, Rathugamage, Jagath, Rätsep, Tõnu, Rauhala, Minna, Raza, Asif, Reddycherla, Naga Raju, Reen, Linus, Refaat, Mohamed, Regli, Luca, Ren, Haijun, Ria, Antonio, Ribeiro, Thales Francisco, Ricci, Alessandro, Richterová, Romana, Ringel, Florian, Robertson, Faith, Rocha, Catarina Mayrink Siqueira Cabral, Rogério, Juvenal de Souza, Romano, Adan Anibal, Rothemeyer, Sally, Rousseau, Gail Rousseau Gail, Roza, Ranette, Rueda, Kevin David Farelo, Ruiz, Raiza, Rundgren, Malin, Rzeplinski, Radoslaw, S.Chandran, Raj, Sadayandi, Ramesh Andi, Sage, William, Sagerer, André Norbert Josef, Sakar, Mustafa, Salami, Mohcine, Sale, Danjuma, Saleh, Youssuf, Sánchez-Viguera, Cristina, Sandila, Saning'o, Sanli, Ahmet Metin, Santi, Laura, Santoro, Antonio, Santos, Aieska Kellen Dantas Dos, Santos, Samir Cezimbra dos, Sanz, Borja, Sapkota, Shabal, Sasidharan, Gopalakrishnan, Sasillo, Ibrahim, Satoskar, Rajeev, Sayar, Ali Caner, Sayee, Vignesh, Scheichel, Florian, Schiavo, Felipe Lourenzon, Schupper, Alexander, Schwarz, Andreas, Scott, Teresa, Seeberger, Esther, Segundo, Claudionor Nogueira Costa, Seidu, Anwar Sadat, Selfa, Antonio, Selmi, Nazan Has, Selvarajah, Claudiya, Şengel, Necmiye, Seule, Martin, Severo, Luiz, Shah, Purva, Shahzad, Muhammad, Shangase, Thobekile, Sharma, Mayur, Shiban, Ehab, Shimber, Emnet, Shokunbi, Temitayo, Siddiqui, Kaynat, Sieg, Emily, Siegemund, Martin, Sikder, Shahidur Rahman, Silva, Ana Cristina Veiga, Silva, Ana, Silva, Pedro Alberto, Singh, Deepinder, Skadden, Carly, Skola, Josef, Skouteli, Eirini, Słoniewski, Pawel, Smith, Brandon, Solanki, Guirish, Solla, Davi Fontoura, Solla, Davi, Sonmez, Ozcan, Sönmez, Müge, Soon, Wai Cheong, Stefini, Roberto, Stienen, Martin Nikolaus, Stoica, Bogdan, Stovell, Matthew, Suarez, Maria Natalia, Sulaiman, Alaa, Suliman, Mazin, Sulistyanto, Adi, Sulubulut, Şeniz, Sungailaite, Sandra, Surbeck, Madlen, Szmuda, Tomasz, Taddei, Graziano, Tadele, Abraham, Taher, Ahmed Saleh Ahmed, Takala, Riikka, Talari, Krishna Murthy, Tan, Bih Huei, Tariciotti, Leonardo, Tarmohamed, Murad, Taroua, Oumayma, Tatti, Emiliano, Tenovuo, Olli, Tetri, Sami, Thakkar, Poojan, Thango, Nqobile, Thatikonda, Satish Kumar, Thesleff, Tuomo, Thomé, Claudius, Thornton, Owen, Timmons, Shelly, Timoteo, Eva Ercilio, Tingate, Campbell, Tliba, Souhil, Tolias, Christos, Toman, Emma, Torres, Ivan, Torres, Luis, Touissi, Youness, Touray, Musa, Tropeano, Maria Pia, Tsermoulas, Georgios, Tsitsipanis, Christos, Turkoglu, Mehmet Erhan, Uçkun, Özhan Merzuk, Ullman, Jamie, Ungureanu, Gheorghe, Urasa, Sarah, Ur-Rehman, Obaid, Uysal, Muhammed, Vakis, Antonios, Valeinis, Egils, Valluru, Vaishali, Vannoy, Debby, Vargas, Pablo, Varotsis, Phillipos, Varshney, Rahul, Vats, Atul, Veljanoski, Damjan, Venturini, Sara, Verma, Abhijit, Villa, Clara, Villa, Genaro, Villar, Sofia, Villard, Erin, Viruez, Antonio, Voglis, Stefanos, Vulekovic, Petar, Wadanamby, Saman, Wagner, Katherine, Walshe, Rebecca, Walter, Jan, Waseem, Marriam, Whitworth, Tony, Wijeyekoon, Ruwani, Williams, Adam, Wilson, Mark, Win, Sein, Winarso, Achmad Wahib Wahju, Ximenes, Abraão Wagner Pessoa, Yadav, Anurag, Yadav, Dipak, Yakoub, Kamal Makram, Yalcinkaya, Ali, Yan, Guizhong, Yaqoob, Eesha, Yepes, Carlos, Yılmaz, Ayfer Nazmiye, Yishak, Betelehem, Yousuf, Farhat Basheer, Zahari, Muhammad Zamzuri, Zakaria, Hussein, Zambonin, Diego, Zavatto, Luca, Zebian, Bassel, Zeitlberger, Anna Maria, Zhang, Furong, Zheng, Fengwei, Ziga, Michal, Clark, David, Joannides, Alexis, Adeleye, Amos Olufemi, Bajamal, Abdul Hafid, Bashford, Tom, Biluts, Hagos, Budohoski, Karol, Ercole, Ari, Fernández-Méndez, Rocío, Figaji, Anthony, Gupta, Deepak Kumar, Härtl, Roger, Iaccarino, Corrado, Khan, Tariq, Rubiano, Andrés, Shabani, Hamisi K, Sichizya, Kachinga, Tewari, Manoj, Tirsit, Abenezer, Thu, Myat, Tripathi, Manjul, Trivedi, Rikin, Devi, Bhagavatula Indira, Servadei, Franco, Menon, David, Kolias, Angelos, and Hutchinson, Peter

Published
2022
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4. Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU study

Author

Robba, Chiara, Graziano, Francesca, Guglielmi, Angelo, Rebora, Paola, Galimberti, Stefania, Taccone, Fabio S, Citerio, Giuseppe, Walter Videtta, Gustavo Domeniconi, María Estrella Giménez, Mariela Fumale, Edgar Daniel Amundarain, Matias Casanova, Michael Reade, Elizabeth Hallt, David Pearson, Ian Seppelt, Raimund Helbok, Valery Davidovich, Geert Meyfroidt, Ilaria Alice Crippa, Liese Mebis, Patrick Biston, Stijn Van De Velde, Glorieux Denis, Pedro Kurtz, Samia Yasin Wayhs, Mypinder Sekhon, Donald Griesdale, Andrea Rigamonti, José Miguel Montes, Rodrigo Pérez-Araos, Jorge H Mejia-Mantilla, Andrés Gempeler, Ray Mendoza, Natasa Kovac, Hedgar Berty Gutiérrez, Vera Spatenkova, Marek Fencl, Roman Gal, Ondrej Hrdy, Kamil Vrbica, Josef Skola, Eva Provaznikova, Jakub Kletecka, Pavel Lavicka, Piergiorgio Bresil, Marianne Levin, Josefine Thomsen, Thomas Egmose Larsen, Henrik Westy Hoffmeyer, Morten Olskjaer Holm, Jesper Borg Andersen, Birgitte Majholm, Margit Smitt, Heidi Shil Eddelien, Manuel Jibaja, Freddy Maldonado, María Fernanda García, Karim Asehnoune, Bertrand Pons, Gérard Audibert, Manon Lucca, Guillaume Besch, Pierluigi Banco, Raphael Cinotti, Hervé Q Uintard, Benjamin Soyer, Anais Caillard, Clement Gakuba, Romain Sonneville, Stefan Wolf, Kristina Fuest, Lea Albrecht, Sarah Grotheer, Sandro M Krieg, Stefan J Schaller, Charikleia Vrettou, Eftychia Kontoudaki, Anna Efthymiou, Elena Palli, Demosthenes Makris, Chrysi Diakaki, Christina Iasonidou, Aikaterini Dimoula, Georgios Koukoulitsios, George Kyriazopoulos, Nikolas Pantelas, Syragoula Tsikriki, Electra Eleni Stamou, Achileas Giannopoulos, Eleni Mouloudi, Ping Shum Hoi, Yan Chan Cheuk, Hewa Kandamby Darshana, Krisztián Tánczos, Gabor Nardai, Zoltan Szentkereszty, Harsh Sapra, Deepak Gupta, Kaveri Sharma, Saurabh Anand, Ankur Luthra, Summit Bloria, Rajeev Chauhan, Nidhi Panda, Ahmad Ozair, Bram Kilapong, Anass Alsudani, Giuseppe Citerio, Alessandra Soragni, Alessandro Motta, Andrea Marudi, Elisabetta Bertellini, Anselmo Caricato, Camilla Gelormini, Eleonora Ioannoni, Eleonora Stival, Serena Silva, Federico Pozzi, Iole Brunetti, Andrea Cortegiani, Edoardo Picetti, Federico Villa, Italo Calamai, Maria Chiara Casadio, Maria Concetta Quartarone, Marzia Grandis, Federico Magni, Silvia Del Bianco, Claudia Bonetti, Virginia Buldini, Aimone Giugni, Simone Maria Zerbi, Marco Carbonara, Antonella Cotoia, Antonio Izzi, Olegs Sabelnikovs, Muhammed Elhadi, Hazem Ahmed, Silvio A Ñamendys Silva, Gilberto Adrian Gasca López, Gentle S Shrestha, Shirish Maskey, Tamanna Bajracharya, Khadka Nilam, Prakash Kafle, Laleet Rajbanshi, Yam Bahadur Roka, Olufemi Idowu, Khan Muhammad Mukhtar, Juan Luis Pinedo Portilla, Klaudyna Kojder, Irene Aragao, Ricardo Freitas, Marco Simoes, Dario Batista, Cecília Pacheco, Fátima Assunção, Luís Lencastre, Pedro Cavaleiro, Mohamed Abdelaty, Alex Gritsan, Sergey Khomiakov Sergey, Dovbysh Nikolay, Yaseen Arabi, Primoz Gradisek, Petra Forjan, Mara Škoti, Suada Filekovic Ribaric, Nataša Milivojevic, Sergeja Kozar, Rafael Badenes, Aaron Blandino Ortiz, Mikel Celaya Lopez, Laura Galarza, Luisa Corral, Africa Lores, Ricard Soley, Laura Pariente, Pablo López Ojeda, Maria Dolores Arias Verdu, Luis Javier Yuste Dominguez, Maria Isabel Gonzalez Perez, Mireia Anglada, Patricia Duque, Ainhoa Serrano, Berta Monleon, Vanessa Blazquez, Mauro Oddo, Samia Abed Maillard, Paola Morelli, John-Paul Miroz, Eva Favre, Walid Sellami, Massimo Lamperti, Jamil Dibu, Richard Sivities, Angelos Kolias, Chris Thompson, Christopher Hawthorne, Justin Roberts, Lara Prisco, Roger Lightfoot, Josè I Suarez, Luci Rivera-Lara, Susanne Muehlschlegel, Juan Padilla, Sanjeev Sivakumar, Daiwai Olson, Robba, C, Graziano, F, Guglielmi, A, Rebora, P, Galimberti, S, Taccone, F, Citerio, G, Robba, Chiara, Graziano, Francesca, Guglielmi, Angelo, Rebora, Paola, Galimberti, Stefania, Taccone, Fabio S, Citerio, Giuseppe, and Walter Videtta, Gustavo Domeniconi, María Estrella Giménez, Mariela Fumale, Edgar Daniel Amundarain, Matias Casanova, Michael Reade, Elizabeth Hallt, David Pearson, Ian Seppelt, Raimund Helbok, Valery Davidovich, Geert Meyfroidt, Ilaria Alice Crippa, Liese Mebis, Patrick Biston, Stijn Van De Velde, Glorieux Denis, Pedro Kurtz, Samia Yasin Wayhs, Mypinder Sekhon, Donald Griesdale, Andrea Rigamonti, José Miguel Montes, Rodrigo Pérez-Araos, Jorge H Mejia-Mantilla, Andrés Gempeler, Ray Mendoza, Natasa Kovac, Hedgar Berty Gutiérrez, Vera Spatenkova, Marek Fencl, Roman Gal, Ondrej Hrdy, Kamil Vrbica, Josef Skola, Eva Provaznikova, Jakub Kletecka, Pavel Lavicka, Vera Spatenkova, Piergiorgio Bresil, Marianne Levin, Piergiorgio Bresil, Josefine Thomsen, Thomas Egmose Larsen, Henrik Westy Hoffmeyer, Morten Olskjaer Holm, Jesper Borg Andersen, Birgitte Majholm, Margit Smitt, Heidi Shil Eddelien, Manuel Jibaja, Freddy Maldonado, María Fernanda García, Karim Asehnoune, Bertrand Pons, Gérard Audibert, Manon Lucca, Guillaume Besch, Pierluigi Banco, Karim Asehnoune, Raphael Cinotti, Hervé Q Uintard, Benjamin Soyer, Anais Caillard, Clement Gakuba, Romain Sonneville, Stefan Wolf, Kristina Fuest, Lea Albrecht, Sarah Grotheer, Sandro M Krieg, Stefan J Schaller, Charikleia Vrettou, Eftychia Kontoudaki, Anna Efthymiou, Elena Palli, Demosthenes Makris, Chrysi Diakaki, Christina Iasonidou, Aikaterini Dimoula, Georgios Koukoulitsios, George Kyriazopoulos, Nikolas Pantelas, Syragoula Tsikriki, Electra Eleni Stamou, Charikleia Vrettou, Achileas Giannopoulos, Eleni Mouloudi, Ping Shum Hoi, Yan Chan Cheuk, Hewa Kandamby Darshana, Krisztián Tánczos, Gabor Nardai, Zoltan Szentkereszty, Harsh Sapra, Deepak Gupta, Kaveri Sharma, Saurabh Anand, Ankur Luthra, Summit Bloria, Rajeev Chauhan, Nidhi Panda, Ahmad Ozair, Bram Kilapong, Anass Alsudani, Giuseppe Citerio, Alessandra Soragni, Alessandro Motta, Andrea Marudi, Elisabetta Bertellini, Anselmo Caricato, Camilla Gelormini, Eleonora Ioannoni, Eleonora Stival, Serena Silva, Federico Pozzi, Iole Brunetti, Andrea Cortegiani, Edoardo Picetti, Federico Villa, Italo Calamai, Maria Chiara Casadio, Maria Concetta Quartarone, Marzia Grandis, Federico Magni, Silvia Del Bianco, Claudia Bonetti, Virginia Buldini, Aimone Giugni, Simone Maria Zerbi, Marco Carbonara, Antonella Cotoia, Antonio Izzi, Olegs Sabelnikovs, Muhammed Elhadi, Hazem Ahmed, Silvio A Ñamendys Silva, Gilberto Adrian Gasca López, Gentle S Shrestha, Shirish Maskey, Tamanna Bajracharya, Khadka Nilam, Prakash Kafle, Laleet Rajbanshi, Yam Bahadur Roka, Olufemi Idowu, Khan Muhammad Mukhtar, Juan Luis Pinedo Portilla, Klaudyna Kojder, Irene Aragao, Ricardo Freitas, Marco Simoes, Dario Batista, Cecília Pacheco, Fátima Assunção, Luís Lencastre, Pedro Cavaleiro, Mohamed Abdelaty, Alex Gritsan, Sergey Khomiakov Sergey, Dovbysh Nikolay, Yaseen Arabi, Primoz Gradisek, Petra Forjan, Mara Škoti, Suada Filekovic Ribaric, Primoz Gradisek, Nataša Milivojevic, Sergeja Kozar, Rafael Badenes, Aaron Blandino Ortiz, Mikel Celaya Lopez, Laura Galarza, Luisa Corral, Africa Lores, Ricard Soley, Laura Pariente, Pablo López Ojeda, Maria Dolores Arias Verdu, Luis Javier Yuste Dominguez, Maria Isabel Gonzalez Perez, Mireia Anglada, Patricia Duque, Ainhoa Serrano, Berta Monleon, Vanessa Blazquez, Mauro Oddo, Samia Abed Maillard, Paola Morelli, John-Paul Miroz, Eva Favre, Walid Sellami, Massimo Lamperti, Jamil Dibu, Richard Sivities, Angelos Kolias, Chris Thompson, Christopher Hawthorne, Justin Roberts, Lara Prisco, Roger Lightfoot, Josè I Suarez, Luci Rivera-Lara, Susanne Muehlschlegel, Juan Padilla, Sanjeev Sivakumar, Daiwai Olson

Subjects
Subarachnoid haemorrhage, Traumatic brain injury, Intracranial pressure, Therapy intensity level, Critical Care and Intensive Care Medicine, Intracranial haemorrhage
Abstract

Purpose: Uncertainties remain about the safety and efficacy of therapies for managing intracranial hypertension in acute brain injured (ABI) patients. This study aims to describe the therapeutical approaches used in ABI, with/without intracranial pressure (ICP) monitoring, among different pathologies and across different countries, and their association with sixmonths mortality and neurological outcome. Methods: A preplanned subanalysis of the SYNAPSE-ICU study, a multicentre, prospective, international, observational cohort study, describing the ICP treatment, graded according to Therapy Intensity Level (TIL) scale, in patients with ABI during the first week of intensive care unit (ICU) admission. Results: 2320 patients were included in the analysis. The median age was 55 (I-III quartiles = 39-69) years, and 800 (34.5%) were female. During the first week from ICU admission, no-basic TIL was used in 382 (16.5%) patients, mild-moderate in 1643 (70.8%), and extreme in 295 cases (eTIL, 12.7%). Patients who received eTIL were younger (median age 49 (I-III quartiles = 35-62) vs 56 (40-69) years, p

Published
2023

6. Casemix, management, and mortality of patients receiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort study

Author

Clark, David, primary, Joannides, Alexis, additional, Adeleye, Amos Olufemi, additional, Bajamal, Abdul Hafid, additional, Bashford, Tom, additional, Biluts, Hagos, additional, Budohoski, Karol, additional, Ercole, Ari, additional, Fernández-Méndez, Rocío, additional, Figaji, Anthony, additional, Gupta, Deepak Kumar, additional, Härtl, Roger, additional, Iaccarino, Corrado, additional, Khan, Tariq, additional, Laeke, Tsegazeab, additional, Rubiano, Andrés, additional, Shabani, Hamisi K, additional, Sichizya, Kachinga, additional, Tewari, Manoj, additional, Tirsit, Abenezer, additional, Thu, Myat, additional, Tripathi, Manjul, additional, Trivedi, Rikin, additional, Devi, Bhagavatula Indira, additional, Servadei, Franco, additional, Menon, David, additional, Kolias, Angelos, additional, Hutchinson, Peter, additional, Abbas, Ghayur, additional, Abdallah, Omar Ibrahim, additional, Abdel-Lateef, Ahmed, additional, Abdifatah, Khalif, additional, Abdullateef, Awfa, additional, Abeygunaratne, Ruvini, additional, Aboellil, Mostafa, additional, Adam, Abass, additional, Adams, Robert, additional, Adeleye, Amos, additional, Adeolu, Augustine, additional, Adji, Novan Krisno, additional, Afianti, Nur, additional, Agarwal, Sudarsan, additional, Aghadi, Ifeanyi Kene, additional, Aguilar, Paúl Martín Méndez, additional, Ahmad, Syeda Rida, additional, Ahmed, Daniyal, additional, Ahmed, Nafees, additional, Aizaz, Haider, additional, Aji, Yunus Kuntawi, additional, Alamri, Alex, additional, Alberto, Augusto Jacinto Mussindo, additional, Alcocer, Luis Alcocer, additional, Alfaro, Lesly Gonzales, additional, Al-Habib, Amro, additional, Alhourani, Ahmad, additional, Ali, Syed Muhammad Rafay, additional, Alkherayf, Fahad, additional, AlMenabbawy, Ahmed, additional, Alshareef, Aliyah, additional, Aminullah, Muhammad Adil s/o, additional, Amjad, Madeha, additional, Amorim, Robson Luis Oliveira de, additional, Anbazhagan, Sathiaprabhu, additional, Andrade, Almir, additional, Antar, Waleed, additional, Anyomih, Theophilus T.K., additional, Aoun, Salah, additional, Apriawan, Tedy, additional, Armocida, Daniele, additional, Arnold, Paul, additional, Arraez, Miguel, additional, Assefa, Temesgen, additional, Asser, Andres, additional, Athiththan, S.P., additional, Attanayake, Deepal, additional, Aung, Maung Maung, additional, Avi, Allan, additional, Ayala, Victor Enrique Antolinez, additional, Azab, Mohammed, additional, Azam, Gaousul, additional, Azharuddin, Mohd, additional, Badejo, Olukemi, additional, Badran, Mohamed, additional, Baig, Azam Ali, additional, Baig, Rehman Ali, additional, Bajaj, Ankur, additional, Baker, Paul, additional, Bala, Renu, additional, Balasa, Artur, additional, Balchin, Ross, additional, Balogun, James, additional, Ban, Vin Shen, additional, Bandi, Bharath Kumar Reddy, additional, Bandyopadhyay, Soham, additional, Bank, Matthew, additional, Barthelemy, Ernest, additional, Bashir, Mohammed Talha, additional, Basso, Luciano Silveira, additional, Basu, Surajit, additional, Batista, Auricelio, additional, Bauer, Marlies, additional, Bavishi, Devi, additional, Beane, Abi, additional, Bejell, Shmuel, additional, Belachew, Anteneh, additional, Belli, Antonio, additional, Belouaer, Amani, additional, Bendahane, Najia El Abbadi, additional, Benjamin, Okanga, additional, Benslimane, Youssef, additional, Benyaiche, Chaymae, additional, Bernucci, Claudio, additional, Berra, Luigi Valentino, additional, Bhebe, Arnold, additional, Bimpis, Alexios, additional, Blanaru, Diana, additional, Bonfim, Jean Claude, additional, Borba, Luis A B, additional, Borcek, Alp Ozgun, additional, Borotto, Erika, additional, Bouhuwaish, Ahmad Elmabri Mohammad, additional, Bourilhon, Facundo, additional, Brachini, Gioia, additional, Breedon, Joshua, additional, Broger, Maximilian, additional, Brunetto, Giacoma Maria Floriana, additional, Bruzzaniti, Placido, additional, Budohoska, Natalia, additional, Burhan, Hira, additional, Calatroni, Maximiliano Luis, additional, Camargo, Catherine, additional, Cappai, Pier Francesco, additional, Cardali, Salvatore Massimiliano, additional, Castaño-Leon, Ana M, additional, Cederberg, David, additional, Celaya, Mikel, additional, Cenzato, Marco, additional, Challa, Lakshmi Madhavi, additional, Charest, Dhanny, additional, Chaurasia, Bipin, additional, Chenna, Rabah, additional, Cherian, Iype, additional, Ching'o, Juliana Henry, additional, Chotai, Tejas, additional, Choudhary, Ajay, additional, Choudhary, Nabeel, additional, Choumin, Florence, additional, Cigic, Tomislav, additional, Ciro, Juan, additional, Conti, Carlo, additional, Corrêa, Antônio Carlos de Souza, additional, Cossu, Giulia, additional, Couto, Maíra Piani, additional, Cruz, Aurora, additional, D'Silva, Divya, additional, D'Aliberti, Giuseppe Antonio, additional, Dampha, Lamin, additional, Daniel, Roy Thomas, additional, Dapaah, Andrew, additional, Darbar, Aneela, additional, Dascalu, Gabriel, additional, Dauda, Happy Amos, additional, Davies, Owain, additional, Delgado-Babiano, Andrea, additional, Dengl, Markus, additional, Despotovic, Marko, additional, Devi, Indira, additional, Dias, Celeste, additional, Dirar, Mohamed, additional, Dissanayake, Melina, additional, Djimbaye, Hananiah, additional, Dockrell, Simon, additional, Dolachee, Ali, additional, Dolgopolova, Julija, additional, Dolgun, Muge, additional, Dow, Abdalrouf, additional, Drusiani, Davide, additional, Dugan, Artjom, additional, Duong, Dinh Tuan, additional, Duong, Trung Kien, additional, Dziedzic, Tomasz, additional, Ebrahim, Ali, additional, El Fatemi, Nizar, additional, El Helou, Antonios El, additional, El Maaqili, Rachid El, additional, El Mostarchid, Brahim El, additional, El Ouahabi, Abdessamad El, additional, Elbaroody, Mohammad, additional, El-Fiki, Ahmed, additional, El-Garci, Ahmed, additional, El-Ghandour, Nasser M.F., additional, Elhadi, Muhammed, additional, Elleder, Vanessa, additional, Elrais, Safa, additional, El-shazly, Mohamed, additional, Elshenawy, Mohamed, additional, Elshitany, Hesham, additional, El-Sobky, Omar, additional, Emhamed, Marwa, additional, Enicker, Basil, additional, Erdogan, Onur, additional, Ertl, Sebastian, additional, Esene, Ignatius, additional, Espinosa, Omar Ocampo, additional, Fadalla, Tarig, additional, Fadelalla, Mohammed, additional, Faleiro, Rodrigo Moreira, additional, Fatima, Nida, additional, Fawaz, Charbel, additional, Fentaw, Assefa, additional, Fernandez, Carla Eiriz, additional, Ferreira, Ana, additional, Ferri, Francesco, additional, Figaji, Tony, additional, Filho, Emerson L B, additional, Fin, Loic, additional, Fisher, Benjamin, additional, Fitra, Fitra, additional, Flores, Alexis Palpan, additional, Florian, Ioan Stefan, additional, Fontana, Vincenzo, additional, Ford, Lauren, additional, Fountain, Daniel, additional, Frade, Jose Maria Roda, additional, Fratto, Antonio, additional, Freyschlag, Christian, additional, Gabin, Aranzazu Sánchez, additional, Gallagher, Clare, additional, Ganau, Mario, additional, Gandia-Gonzalez, Maria Luisa, additional, Garcia, Andoni, additional, Garcia, Borja Hernandez, additional, Garusinghe, Sanjeewa, additional, Gebreegziabher, Biniam, additional, Gelb, Adrian, additional, George, Jerome St, additional, Germanò, Antonino Francesco, additional, Ghetti, Ilaria, additional, Ghimire, Prajwal, additional, Giammarusti, Alessandro, additional, Gil, Jose Luis, additional, Gkolia, Panagiota, additional, Godebo, Yoseph, additional, Gollapudi, Prakash Rao, additional, Golubovic, Jagos, additional, Gomes, Jeremias Fernando, additional, Gonzales, Javier, additional, Gormley, William, additional, Gots, Alexander, additional, Gribaudi, Giulia Letizia, additional, Griswold, Dylan, additional, Gritti, Paolo, additional, Grobler, Ruan, additional, Gunawan, Rudy, additional, Hailemichael, Birhanu, additional, Hakkou, Elmehdi, additional, Haley, Mark, additional, Hamdan, Alhafidz, additional, Hammed, Ali, additional, Hamouda, Waeel, additional, Hamzah, Nurul Ashikin, additional, Han, Nyein Latt, additional, Hanalioglu, Sahin, additional, Haniffa, Rashan, additional, Hanko, Martin, additional, Hanrahan, John, additional, Hardcastle, Timothy, additional, Hassani, Fahd Derkaoui, additional, Heidecke, Volkmar, additional, Helseth, Eirik, additional, Hernández-Hernández, Miguel Ángel, additional, Hickman, Zachary, additional, Hoang, Le Minh Chau, additional, Hollinger, Alexa, additional, Horakova, Lenka, additional, Hossain-Ibrahim, Kismet, additional, Hou, Boru, additional, Hoz, Samer, additional, Hsu, Janine, additional, Hunn, Martin, additional, Hussain, Madiha, additional, Iacopino, Giorgia, additional, Ideta, Mylena Miki Lopes, additional, Iglesias, Irene, additional, Ilunga, Ali, additional, Imtiaz, Nafiz, additional, Islam, Rafiza, additional, Ivashchenko, Serge, additional, Izirouel, Karim, additional, Jabal, Mohamed Sobhi, additional, Jabal, Soubhi, additional, Jabang, John Nute, additional, Jamjoom, Aimun, additional, Jan, Irfan, additional, Jarju, Landing BM, additional, Javed, Saad, additional, Jelaca, Bojan, additional, Jhawar, Sukhdeep Singh, additional, Jiang, Ting Ting, additional, Jimenez, Fernando, additional, Jiris, Jorge, additional, Jithoo, Ron, additional, Johnson, Walt, additional, Joseph, Mathew, additional, Joshi, Rameshman, additional, Junttila, Eija, additional, Jusabani, Mubashir, additional, Kache, Stephen Akau, additional, Kadali, Satyavara Prasad, additional, Kalkmann, Gabriela F, additional, Kamboh, Usman, additional, Kandel, Hitham, additional, Karakus, Ahmet Kamil, additional, Kassa, Mengistu, additional, Katila, Ari, additional, Kato, Yoko, additional, Keba, Martin, additional, Kehoe, Kristy, additional, Kertmen, Huseyin Hayri, additional, Khafaji, Soha, additional, Khajanchi, Monty, additional, Khan, Mohammed, additional, Khan, Muhammad Mukhtar, additional, Khan, Sohail Daud, additional, Khizar, Ahtesham, additional, Khriesh, Amir, additional, Kierońska, Sara, additional, Kisanga, Paul, additional, Kivevele, Boniface, additional, Koczyk, Kacper, additional, Koerling, Anna-Lucia, additional, Koffenberger, Danielle, additional, Kõiv, Kennet, additional, Kõiv, Leho, additional, Kolarovszki, Branislav, additional, König, Marton, additional, Könü-Leblebicioglu, Dilek, additional, Koppala, Santhoshi Devi, additional, Korhonen, Tommi, additional, Kostkiewicz, Boguslaw, additional, Kostyra, Kacper, additional, Kotakadira, Srinivas, additional, Kotha, Arjun Reddy, additional, Kottakki, Madhu Narayana Rao, additional, Krajcinovic, Nenad, additional, Krakowiak, Michal, additional, Kramer, Andreas, additional, Krishnamoorthy, Selvamuthukumaran, additional, Kumar, Ashok, additional, Kumar, Pankaj, additional, Kumar, Pradhumna, additional, Kumarasinghe, Nilaksha, additional, Kuncha, Gowtham, additional, Kutty, Raja K., additional, Lafta, Ghazwan, additional, Lammy, Simon, additional, Lapolla, Pierfrancesco, additional, Lardani, Jacopo, additional, Lasica, Nebojsa, additional, Lastrucci, Giancarlo, additional, Launey, Yoann, additional, Lavalle, Laura, additional, Lawrence, Tim, additional, Lazaro, Albert, additional, Lebed, Vitalii, additional, Leinonen, Ville, additional, Lemeri, Lawrence, additional, Levi, Leon, additional, Lim, Jia Yi, additional, Lim, Xiao Yi, additional, Linares-Torres, Jorge, additional, Lippa, Laura, additional, Lisboa, Lurdes, additional, Liu, Jinfang, additional, Liu, Ziyuan, additional, Lo, William B, additional, Lodin, Jan, additional, Loi, Federico, additional, Londono, Daniella, additional, Lopez, Pedro Antonio Gomez, additional, López, Cristina Barceló, additional, Lotbiniere-Bassett, Madeleine De, additional, Lulens, Rihards, additional, Luna, Facundo Hector, additional, Luoto, Teemu, additional, M.V., Vijaya Sekhar, additional, Mabovula, Ndyebo, additional, MacAllister, Matthew, additional, Macie, Alcina Americo, additional, Maduri, Rodolfo, additional, Mahfoud, Moufid, additional, Mahmood, Ashraf, additional, Mahmoud, Fathia, additional, Mahoney, Dominic, additional, Makhlouf, Wissam, additional, Malcolm, George, additional, Malomo, Adefolarin, additional, Malomo, Toluyemi, additional, Mani, Manoranjitha Kumari, additional, Marçal, Tomás Gazzinelli, additional, Marchello, Jacopo, additional, Marchesini, Nicolò, additional, Marhold, Franz, additional, Marklund, Niklas, additional, Martín-Láez, Rubén, additional, Mathaneswaran, Vickneswaran, additional, Mato-Mañas, David José, additional, Maye, Helen, additional, McLean, Aaron Lawson, additional, McMahon, Catherine, additional, Mediratta, Saniya, additional, Mehboob, Mehreen, additional, Meneses, Alisson, additional, Mentri, Nesrine, additional, Mersha, Hagos, additional, Mesa, Ana Milena, additional, Meyer, Cristy, additional, Millward, Christopher, additional, Mimbir, Salomao Amone, additional, Mingoli, Andrea, additional, Mishra, Parashruram, additional, Mishra, Tejesh, additional, Misra, Basant, additional, Mittal, Siddharth, additional, Mohammed, Imran, additional, Moldovan, Ioana, additional, Molefe, Masechaba, additional, Moles, Alexis, additional, Moodley, Preston, additional, Morales, Mario Augusto Narváez, additional, Morgan, Lucy, additional, Morillo, German Del Castillo, additional, Moustafa, Wahab, additional, Moustakis, Nikolaos, additional, Mrichi, Salma, additional, Munjal, Satya Shiva, additional, Muntaka, Abdul-Jalilu Mohammed, additional, Naicker, Denver, additional, Nakashima, Paulo E H, additional, Nandigama, Pratap Kumar, additional, Nash, Samantha, additional, Negoi, Ionut, additional, Negoita, Valetina, additional, Neupane, Samundra, additional, Nguyen, Manh Hung, additional, Niantiarno, Fajar Herbowo, additional, Noble, Abbi, additional, Nor, Mohd Arman Muhamad, additional, Nowak, Blazej, additional, Oancea, Andrei, additional, O'Brien, Frazer, additional, Okere, Oghenekevwe, additional, Olaya, Sandra, additional, Oliveira, Leandro, additional, Oliveira, Louise Makarem, additional, Omar, Fatma, additional, Ononeme, Okezi, additional, Opšenák, René, additional, Orlandini, Simone, additional, Osama, Alrobah, additional, Osei-Poku, Dorcas, additional, Osman, Haytham, additional, Otero, Alvaro, additional, Ottenhausen, Malte, additional, Otzri, Shuli, additional, Outani, Oumaima, additional, Owusu, Emmanuel Abem, additional, Owusu-Agyemang, Kevin, additional, Ozair, Ahmad, additional, Ozoner, Baris, additional, Paal, Elli, additional, Paiva, Mauro Sérgio, additional, Paiva, Wellingson, additional, Pandey, Sharad, additional, Pansini, Gastone, additional, Pansini, Luigi, additional, Pantel, Tobias, additional, Pantelas, Nikolaos, additional, Papadopoulos, Konstantinos, additional, Papic, Vladimir, additional, Park, Kee, additional, Park, Nick, additional, Paschoal, Eric Homero Albuquerque, additional, Paschoalino, Mylla Christie de Oliveira, additional, Pathi, Rajesh, additional, Peethambaran, Anilkumar, additional, Pereira, Thiago Andrade, additional, Perez, Irene Panero, additional, Pérez, Claudio José Piqueras, additional, Periyasamy, Tamilanandh, additional, Peron, Stefano, additional, Phillips, Michael, additional, Picazo, Sofía Sotos, additional, Pinar, Ertugrul, additional, Pinggera, Daniel, additional, Piper, Rory, additional, Pirakash, Pathmanesan, additional, Popadic, Branko, additional, Posti, Jussi P., additional, Prabhakar, Rajmohan Bhanu, additional, Pradeepan, Sivanesalingam, additional, Prasad, Manjunath, additional, Prieto, Paola Calvachi, additional, Prince, Ron, additional, Prontera, Andrea, additional, Provaznikova, Eva, additional, Quadros, Danilo, additional, Quintero, Nezly Jadid Romero, additional, Qureshi, Mahmood, additional, Rabiel, Happiness, additional, Rada, Gabriel, additional, Ragavan, Sivagnanam, additional, Rahman, Jueria, additional, Ramadhan, Omar, additional, Ramaswamy, Padma, additional, Rashid, Sakina, additional, Rathugamage, Jagath, additional, Rätsep, Tõnu, additional, Rauhala, Minna, additional, Raza, Asif, additional, Reddycherla, Naga Raju, additional, Reen, Linus, additional, Refaat, Mohamed, additional, Regli, Luca, additional, Ren, Haijun, additional, Ria, Antonio, additional, Ribeiro, Thales Francisco, additional, Ricci, Alessandro, additional, Richterová, Romana, additional, Ringel, Florian, additional, Robertson, Faith, additional, Rocha, Catarina Mayrink Siqueira Cabral, additional, Rogério, Juvenal de Souza, additional, Romano, Adan Anibal, additional, Rothemeyer, Sally, additional, Rousseau, Gail Rousseau Gail, additional, Roza, Ranette, additional, Rueda, Kevin David Farelo, additional, Ruiz, Raiza, additional, Rundgren, Malin, additional, Rzeplinski, Radoslaw, additional, S.Chandran, Raj, additional, Sadayandi, Ramesh Andi, additional, Sage, William, additional, Sagerer, André Norbert Josef, additional, Sakar, Mustafa, additional, Salami, Mohcine, additional, Sale, Danjuma, additional, Saleh, Youssuf, additional, Sánchez-Viguera, Cristina, additional, Sandila, Saning'o, additional, Sanli, Ahmet Metin, additional, Santi, Laura, additional, Santoro, Antonio, additional, Santos, Aieska Kellen Dantas Dos, additional, Santos, Samir Cezimbra dos, additional, Sanz, Borja, additional, Sapkota, Shabal, additional, Sasidharan, Gopalakrishnan, additional, Sasillo, Ibrahim, additional, Satoskar, Rajeev, additional, Sayar, Ali Caner, additional, Sayee, Vignesh, additional, Scheichel, Florian, additional, Schiavo, Felipe Lourenzon, additional, Schupper, Alexander, additional, Schwarz, Andreas, additional, Scott, Teresa, additional, Seeberger, Esther, additional, Segundo, Claudionor Nogueira Costa, additional, Seidu, Anwar Sadat, additional, Selfa, Antonio, additional, Selmi, Nazan Has, additional, Selvarajah, Claudiya, additional, Şengel, Necmiye, additional, Seule, Martin, additional, Severo, Luiz, additional, Shah, Purva, additional, Shahzad, Muhammad, additional, Shangase, Thobekile, additional, Sharma, Mayur, additional, Shiban, Ehab, additional, Shimber, Emnet, additional, Shokunbi, Temitayo, additional, Siddiqui, Kaynat, additional, Sieg, Emily, additional, Siegemund, Martin, additional, Sikder, Shahidur Rahman, additional, Silva, Ana Cristina Veiga, additional, Silva, Ana, additional, Silva, Pedro Alberto, additional, Singh, Deepinder, additional, Skadden, Carly, additional, Skola, Josef, additional, Skouteli, Eirini, additional, Słoniewski, Pawel, additional, Smith, Brandon, additional, Solanki, Guirish, additional, Solla, Davi Fontoura, additional, Solla, Davi, additional, Sonmez, Ozcan, additional, Sönmez, Müge, additional, Soon, Wai Cheong, additional, Stefini, Roberto, additional, Stienen, Martin Nikolaus, additional, Stoica, Bogdan, additional, Stovell, Matthew, additional, Suarez, Maria Natalia, additional, Sulaiman, Alaa, additional, Suliman, Mazin, additional, Sulistyanto, Adi, additional, Sulubulut, Şeniz, additional, Sungailaite, Sandra, additional, Surbeck, Madlen, additional, Szmuda, Tomasz, additional, Taddei, Graziano, additional, Tadele, Abraham, additional, Taher, Ahmed Saleh Ahmed, additional, Takala, Riikka, additional, Talari, Krishna Murthy, additional, Tan, Bih Huei, additional, Tariciotti, Leonardo, additional, Tarmohamed, Murad, additional, Taroua, Oumayma, additional, Tatti, Emiliano, additional, Tenovuo, Olli, additional, Tetri, Sami, additional, Thakkar, Poojan, additional, Thango, Nqobile, additional, Thatikonda, Satish Kumar, additional, Thesleff, Tuomo, additional, Thomé, Claudius, additional, Thornton, Owen, additional, Timmons, Shelly, additional, Timoteo, Eva Ercilio, additional, Tingate, Campbell, additional, Tliba, Souhil, additional, Tolias, Christos, additional, Toman, Emma, additional, Torres, Ivan, additional, Torres, Luis, additional, Touissi, Youness, additional, Touray, Musa, additional, Tropeano, Maria Pia, additional, Tsermoulas, Georgios, additional, Tsitsipanis, Christos, additional, Turkoglu, Mehmet Erhan, additional, Uçkun, Özhan Merzuk, additional, Ullman, Jamie, additional, Ungureanu, Gheorghe, additional, Urasa, Sarah, additional, Ur-Rehman, Obaid, additional, Uysal, Muhammed, additional, Vakis, Antonios, additional, Valeinis, Egils, additional, Valluru, Vaishali, additional, Vannoy, Debby, additional, Vargas, Pablo, additional, Varotsis, Phillipos, additional, Varshney, Rahul, additional, Vats, Atul, additional, Veljanoski, Damjan, additional, Venturini, Sara, additional, Verma, Abhijit, additional, Villa, Clara, additional, Villa, Genaro, additional, Villar, Sofia, additional, Villard, Erin, additional, Viruez, Antonio, additional, Voglis, Stefanos, additional, Vulekovic, Petar, additional, Wadanamby, Saman, additional, Wagner, Katherine, additional, Walshe, Rebecca, additional, Walter, Jan, additional, Waseem, Marriam, additional, Whitworth, Tony, additional, Wijeyekoon, Ruwani, additional, Williams, Adam, additional, Wilson, Mark, additional, Win, Sein, additional, Winarso, Achmad Wahib Wahju, additional, Ximenes, Abraão Wagner Pessoa, additional, Yadav, Anurag, additional, Yadav, Dipak, additional, Yakoub, Kamal Makram, additional, Yalcinkaya, Ali, additional, Yan, Guizhong, additional, Yaqoob, Eesha, additional, Yepes, Carlos, additional, Yılmaz, Ayfer Nazmiye, additional, Yishak, Betelehem, additional, Yousuf, Farhat Basheer, additional, Zahari, Muhammad Zamzuri, additional, Zakaria, Hussein, additional, Zambonin, Diego, additional, Zavatto, Luca, additional, Zebian, Bassel, additional, Zeitlberger, Anna Maria, additional, Zhang, Furong, additional, Zheng, Fengwei, additional, and Ziga, Michal, additional

Published
2022
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7. Decompressive craniotomy: an international survey of practice

Author

Mohan, Midhun, Layard Horsfall, Hugo, Solla, Davi Jorge Fontoura, Robertson, Faith C, Adeleye, Amos O, Teklemariam, Tsegazeab Laeke, Khan, Muhammad Mukhtar, Servadei, Franco, Khan, Tariq, Karekezi, Claire, Rubiano, Andres M, Hutchinson, Peter J, Paiva, Wellingson Silva, Kolias, Angelos G, Devi, B Indira, NIHR Global Health Research Group On Neurotrauma, Mohan, Midhun [0000-0002-1865-8623], and Apollo - University of Cambridge Repository

Subjects
Adult, Decompressive Craniectomy, Health Knowledge, Attitudes, Practice, Neurosurgery, Decompressive craniotomy, Middle Aged, Hinge craniotomy, Stroke, Traumatic brain injury, Neurosurgeons, Surveys and Questionnaires, Brain Injuries, Traumatic, Floating craniotomy, Hematoma, Subdural, Acute, Humans, Randomized Controlled Trials as Topic
Abstract

Funder: National Institute for Health Research; doi: http://dx.doi.org/10.13039/501100000272, Funder: University of Cambridge and the Royal College of Surgeons of England, BACKGROUND: Traumatic brain injury (TBI) and stroke have devastating consequences and are major global public health issues. For patients that require a cerebral decompression after suffering a TBI or stroke, a decompressive craniectomy (DC) is the most commonly performed operation. However, retrospective non-randomized studies suggest that a decompressive craniotomy (DCO; also known as hinge or floating craniotomy), where a bone flap is replaced but not rigidly fixed, has comparable outcomes to DC. The primary aim of this project was to understand the current extent of usage of DC and DCO for TBI and stroke worldwide. METHOD: A questionnaire was designed and disseminated globally via emailing lists and social media to practicing neurosurgeons between June and November 2019. RESULTS: We received 208 responses from 60 countries [40 low- and middle-income countries (LMICs)]. DC is used more frequently than DCO, however, about one-quarter of respondents are using a DCO in more than 25% of their patients. The three top indications for a DCO were an acute subdural hematoma (ASDH) and a GCS of 9-12, ASDH with contusions and a GCS of 3-8, and ASDH with contusions and a GCS of 9-12. There were 8 DCO techniques used with the majority (60/125) loosely tying sutures to the bone flap. The majority (82%) stated that they were interested in collaborating on a randomized trial of DCO vs. DC. CONCLUSION: Our results show that DCO is a procedure carried out for TBI and stroke, especially in LMICs, and most commonly for an ASDH. The majority of the respondents were interested in collaborating on a is a future randomized trial.

Published
2021
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8. P2.004 A scoping review on strategies and interventions in global neurotrauma prevention

Author

Selveindran, Santhani M, primary, Hutchinson, Peter, additional, Tango, Tamara, additional, Khan, Muhammad Mukhtar, additional, Simadibrata, Daniel, additional, Brayne, Carol, additional, Hill, Christine, additional, Kolias, Angelos, additional, Servadei, Franco, additional, Joannides, Alexis, additional, Rubiano, Andres, additional, and Shabani, Hamisi, additional

Published
2021
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9. Additional file 5 of Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review

Author

Santhani M Selveindran, Tango, Tamara, Khan, Muhammad Mukhtar, Simadibrata, Daniel Martin, Hutchinson, Peter J. A., Brayne, Carol, Hill, Christine, Servadei, Franco, Kolias, Angelos G., Rubiano, Andres M., Joannides, Alexis J., and Hamisi K. Shabani

Abstract

Additional file 5. Characteristics of included reviews after full-text screening

Published
2020
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10. Additional file 3 of Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review

Author

Santhani M Selveindran, Tango, Tamara, Khan, Muhammad Mukhtar, Simadibrata, Daniel Martin, Hutchinson, Peter J. A., Brayne, Carol, Hill, Christine, Servadei, Franco, Kolias, Angelos G., Rubiano, Andres M., Joannides, Alexis J., and Hamisi K. Shabani

Subjects
MathematicsofComputing_GENERAL, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Abstract

Additional file 3. List of databases and websites searched for grey literature.

Published
2020
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11. Additional file 1 of Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review

Author

Santhani M Selveindran, Tango, Tamara, Khan, Muhammad Mukhtar, Simadibrata, Daniel Martin, Hutchinson, Peter J. A., Brayne, Carol, Hill, Christine, Servadei, Franco, Kolias, Angelos G., Rubiano, Andres M., Joannides, Alexis J., and Hamisi K. Shabani

Abstract

Additional file 1. Preferred reporting items for systematic reviews and meta-analyses extension for scoping reviews (PRISMA-ScR) checklist.

Published
2020
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12. Additional file 4 of Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review

Author

Santhani M Selveindran, Tango, Tamara, Khan, Muhammad Mukhtar, Simadibrata, Daniel Martin, Hutchinson, Peter J. A., Brayne, Carol, Hill, Christine, Servadei, Franco, Kolias, Angelos G., Rubiano, Andres M., Joannides, Alexis J., and Hamisi K. Shabani

Abstract

Additional file 4. Characteristics of included primary studies after full-text screening (primary and secondary prevention).

Published
2020
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13. Additional file 2 of Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review

Author

Santhani M Selveindran, Tango, Tamara, Khan, Muhammad Mukhtar, Simadibrata, Daniel Martin, Hutchinson, Peter J. A., Brayne, Carol, Hill, Christine, Servadei, Franco, Kolias, Angelos G., Rubiano, Andres M., Joannides, Alexis J., and Hamisi K. Shabani

Abstract

Additional file 2. Search strategy for Medline 1946 to date: returned 18,013 records.

Published
2020
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15. Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: A scoping review

Author

Selveindran, Santhani M, primary, Tango, Tamara, additional, Khan, Muhammad Mukhtar, additional, Simadibrata, Daniel Martin, additional, Hutchinson, Peter JA, additional, Brayne, Carol, additional, Hill, Christine, additional, Servadei, Franco, additional, Kolias, Angelos G, additional, Rubiano, Andres M, additional, Joannides, Alexis J, additional, and Shabani, Hamisi K, additional

Published
2020
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16. Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review protocol

Author

M Selveindran, Santhani, primary, Khan, Muhammad Mukhtar, additional, Simadibrata, Daniel Martin, additional, Hutchinson, Peter J A, additional, Brayne, Carol, additional, Hill, Christine, additional, Kolias, Angelos, additional, Joannides, Alexis J, additional, Servadei, Franco, additional, Rubiano, Andres M, additional, and Shabani, Hamisi K, additional

Published
2019
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17. Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review protocol.

Author

Selveindran, Santhani M., Khan, Muhammad Mukhtar, Simadibrata, Daniel Martin, Hutchinson, Peter J. A., Brayne, Carol, Hill, Christine, Kolias, Angelos, Joannides, Alexis J., Servadei, Franco, Rubiano, Andres M., and Shabani, Hamisi K.

Abstract

Introduction Neurotrauma is an important global health problem. This ‘silent epidemic’ is a major cause of death and disability in adolescents and young adults, with significant societal and economic impacts. Globally, the largest cause of neurotrauma is road traffic collisions (RTCs). Neurotrauma and RTCs are largely preventable, and many preventative strategies and interventions have been established and implemented over the last decades, particularly in high-income countries. However, these approaches may not be applicable globally, due to variations in environment, resources, population, culture and infrastructure. This paper outlines the protocol for a scoping review, which seeks to map the evidence on strategies and interventions in neurotrauma and RTCs prevention globally, and to ascertain contextual factors that influence their implementation. Methods and analysis This scoping review will use the established methodology by Arksey and O’Malley. Eligible studies will be identified from five electronic databases (MEDLINE, EMBASE, CINAHL, Global Health/EBSCO and Cochrane Database of Systematic Reviews) and grey literature sources. We will also carry out bibliographical and citation searching of included studies. A two-stage selection process, which involves screening of titles and abstracts, followed by full-text screening, will be used to determine eligible studies which will undergo data abstraction using a customised, piloted data extraction sheet. The extracted data will be presented using evidence mapping and a narrative summary. Ethics and dissemination Ethical approval is not required for this scoping review, which is the first step in a multiphase public health research project on the global prevention of neurotrauma. The final review will be submitted for publication to a scientific journal, and results will be presented at appropriate conferences, workshops and meetings. Protocol registered on 5 April 2019 with Open Science Framework [ABSTRACT FROM AUTHOR]

Published
2019
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18. EFFECTIVENESS OF TRANSCRANIAL DURAL REPAIR FOR EARLY POST-TRAUMATIC CEREBROSPINAL FLUID LEAKS.

Author

Rahman, Zia Ur and Khan, Muhammad Mukhtar

Subjects
*HEAD injuries, *CEREBROSPINAL fluid, *CEREBRAL revascularization, *NEUROSURGERY, *INTRACRANIAL pressure, *CEREBROSPINAL fluid leak
Abstract

Objective: To determine the effectiveness of transcranial dural repair in the management of early traumatic cerebrospinal fluid (CSF) rhinorrhea. Methodology: This study was conducted at Department of Neurosurgery, Hayatabad Medical Complex, Peshawar, from March 2015 to February 2017. Cases of traumatic CSF rhinorrhea of less than 7 days' duration, from both genders without age discrimination were included. Patients with chronic, spontaneous and iatrogenic CSF leaks were excluded. CSF rhinorrhea was diagnosed on clinical as well as radiological studies. Results: Total 60 patients were studied. Age range was 7 to 57 years with mean age of 29 ±1.2 years. There were 46 (76.6%) males and 14 (23.3%) were females. The causes of head trauma were road traffic accident in 36 (60%), fall from height in 14 (23.3%) and miscellaneous were noted in 10 (16.67%). Overall, postoperative complications were observed in a total of 13 (21.7%) patients. The success rate as denoted by closure of the CSF leak was 90%. Complications of surgery included recurrent CSF leak in 6 (10%) patients, 4 (6.67%) patients had meningitis, 10 (16.67%) patients developed pneumocephalus while 06 (10%) patients were complaining of loss of smell after surgery. Conclusion: Transcranial dural repair is the safe and effective way to treat post-traumatic CSF rhinorrhea and prevent its complications. [ABSTRACT FROM AUTHOR]

Published
2018

19. Surgical Management of Soft Tissue Sarcoma.

Author

Khan, Muhammad Mukhtar, Waqar, S. H., Mahmood, Raja Amjad, and Zahid, M. A.

Subjects
*SOFT tissue tumors, *TERTIARY care, *CANCER radiotherapy, *CANCER chemotherapy, *METASTASIS
Abstract

Background: To study the management pattern of soft tissue sarcomas in a tertiary care setting Methods: In this descriptive study patients who were operated for soft tissue masses were included. Intra-operative findings, procedure details and postoperative orders were recorded. Postoperative chemo-radiotherapy records were reviewed and recorded. Depth of the tumour was grouped as deeper or superficial than 5 cm. The follow up records were accessed from the outpatient department and any surgical complications were recorded up to three years.Staging was done using clinical and radiological criteria taking into account the histological grade,tumour size , depth, local lymph node invasion and metastasis.Surgical procedure for removal of STS are wide local excision (WLE), intralesional excision (IE) or tumor debulking, marginal excision (ME) and radical excision (RE). Results: Sixty eight patients with mean age of 43.0 ± 17.258 SD were diagnosed as cases of soft tissue sarcomas. Male to female ratio was 3.25:1.The most common histopathological variety was malignant fibrous histiocytoma (35.3%) , followed by Rhabdomyosarcoma(30%). Most common involved site was lower limbs (35.3%).Wide local excision was performed in majority (82.4%) . Most common postop complication was wound infection (10.3%) Conclusion: Clinicians must be agile about the nature of these tumours and their referral to a specialist surgeon for further management. Prompt diagnosis, accurate investigations and early intervention will benefit the patients and help us understand this disease entity. [ABSTRACT FROM AUTHOR]

Published
2018

20. POSITIVE CT BRAIN DURING EARLY POSTOPERATIVE PERIOD IN HEAD INJURY PATIENTS: IMPACT ON CLINICAL COURSE AND OUTCOME.

Author

Zia Ur Rehman, Khan, Muhammad Mukhtar, and Ayub, Shahid

Subjects
*BRAIN tomography, *HEAD injury diagnosis, *HEAD surgery, *NEUROLOGY, *COMPUTED tomography
Abstract

Objectives: To assess the impact of positive postoperative CT head during the initial 72 hours on overall clinical course and outcome. Methodology: 157 patients of head trauma who underwent cranial surgery were prospectively included. All patients underwent a repeat head CT during the initial 72 hours or as was indicated by neurological status of the patient. Data was collected about patient demographics, initial CT diagnosis, repeat CT findings, re-operation if performed, GCS at discharge, mortality and outcome in terms of GOS. Data was analysed for impact of positive finding in postoperative CT head and its impact on clinical course and outcome. Results: The overall mean age was 34.25 ±11.59 years with a mean arrival GCS of 9.2 ±2.32. The mean time to first postoperative CT was 21.45 ±9.83 hours. The postoperative CT scan was positive in 29 (18.5%) patients in which 16 (10.2%) cases required re-intervention. Overall mortality was 19 (12.1%), of which 9 (44.1%) had a positive post-operative CT scan and 4 (21.1%) of them underwent a repeat intervention. 2.3% of patients with negative CT were re-operated while 44.8% were re-operated in the positive CT (p <0.0001). Similarly, mortality was 7.8% in the negative CT group while it was 31.0% in the positive CT group (p <0.0001). Conclusions: Positive follow-up CT scan during early post-operative period can affect significantly the clinical course and neurological outcome of patients. [ABSTRACT FROM AUTHOR]

Published
2017

21. Outcome of second-degree burns in paediatric patients: Efficacy of antibiotic coating dressing.

Author

Shah, Habib Ullah, Gul, Huma, Khan, Muhammad Mukhtar, and Khan, Rashid

Subjects
TREATMENT for burns & scalds, ANTIBIOTICS, DRUG efficacy, DRUG coatings, PEDIATRICS, DEVELOPING countries
Abstract

Objective: To determine the long-term outcome of burns in paediatric age patients for antibiotic coated dressing using a special technique with emphasis on its role in developing countries. Methods: Th is is a retrospective review of prospectively collected data of paediatric age patients treated at Habib Burns Centre, Peshawar, Pakistan between January 2013 and December 2015. Data analysed included patient demographics, burn characteristics (burn type, body surface area, time to presentation and culture positivity of wound surface), treatment methods with dressing and debridement, in terms of total healing time, length of hospital stay, complications and mortality. Results: 1,112 pediatric patients (49.2% males and 50.8% females) with mean age of 10.02 years ±3.37 SD. The mean total body surface area (TBSA) was 18.16% ± 8.59 SD. Mean healing time was 14.41 days ± 5.75 SD. Mean length of stay (LOS) was 8.13 days ± 3.66 SD. Mean time to presentation was 40.13 hours ±43.06 SD. The majority of patients presented during the months of June and July. The overall mortality rate was 2.3% (26). Strong predictors of severe morbidity and mortality were concomitant inhalational injury, body surface area (<0.001). Conclusion: Coating with a mixture of antibiotic and silver ointments followed by covering the wound with antibiotic impregnated mesh dressing gives favourable results in partial thickness burn wounds and due to its cost eff ectiveness should be utilised in economically developing countries. [ABSTRACT FROM AUTHOR]

Published
2017

22. Decompressive craniotomy: an international survey of practice.

Author

Mohan M, Layard Horsfall H, Solla DJF, Robertson FC, Adeleye AO, Teklemariam TL, Khan MM, Servadei F, Khan T, Karekezi C, Rubiano AM, Hutchinson PJ, Paiva WS, Kolias AG, and Devi BI

Subjects
Adult, Brain Injuries, Traumatic surgery, Decompressive Craniectomy standards, Hematoma, Subdural, Acute surgery, Humans, Middle Aged, Neurosurgeons psychology, Randomized Controlled Trials as Topic, Stroke surgery, Surveys and Questionnaires, Decompressive Craniectomy methods, Health Knowledge, Attitudes, Practice
Abstract

Background: Traumatic brain injury (TBI) and stroke have devastating consequences and are major global public health issues. For patients that require a cerebral decompression after suffering a TBI or stroke, a decompressive craniectomy (DC) is the most commonly performed operation. However, retrospective non-randomized studies suggest that a decompressive craniotomy (DCO; also known as hinge or floating craniotomy), where a bone flap is replaced but not rigidly fixed, has comparable outcomes to DC. The primary aim of this project was to understand the current extent of usage of DC and DCO for TBI and stroke worldwide., Method: A questionnaire was designed and disseminated globally via emailing lists and social media to practicing neurosurgeons between June and November 2019., Results: We received 208 responses from 60 countries [40 low- and middle-income countries (LMICs)]. DC is used more frequently than DCO, however, about one-quarter of respondents are using a DCO in more than 25% of their patients. The three top indications for a DCO were an acute subdural hematoma (ASDH) and a GCS of 9-12, ASDH with contusions and a GCS of 3-8, and ASDH with contusions and a GCS of 9-12. There were 8 DCO techniques used with the majority (60/125) loosely tying sutures to the bone flap. The majority (82%) stated that they were interested in collaborating on a randomized trial of DCO vs. DC., Conclusion: Our results show that DCO is a procedure carried out for TBI and stroke, especially in LMICs, and most commonly for an ASDH. The majority of the respondents were interested in collaborating on a is a future randomized trial.

Published
2021
Full Text
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23. Outcome Analysis Of Two Different Injection Solutions For Epidural Injection In Radicular Lumbar Backache Syndromes.

Author

Saqib M, Bhatti SN, Khan MA, Samad K, Khan MM, Khan Afridi EM, Khan R, and Khan MI

Subjects
Drug Therapy, Combination, Female, Humans, Injections, Epidural, Male, Middle Aged, Prospective Studies, Visual Analog Scale, Anesthetics, Local therapeutic use, Bupivacaine therapeutic use, Glucocorticoids therapeutic use, Low Back Pain drug therapy, Methylprednisolone therapeutic use
Abstract

Background: Backache is a significant source of disability and suffering in our society. The treatment modalities need continued enhancement in order to achieve the desired goals of lowering morbidity and financial losses while improving the response of the patient., Methods: This prospective comparative study was conducted at the department of Orthopaedics and Spine Surgery, Khyber Teaching Hospital Peshawar from July 2013 to June 2015. Two interventional groups were designated; Group 1 was comprised of 54 patients who were injected with epidural bupivacaine plus methylprednisolone while Group 2 included 55 patients who were injected with bupivacaine only. Outcome was assessed using the visual analogue scale and Oswestry disability index (ODI)., Results: Fifty-five female and 54 male patients with mean age 49.37 years±10.46 SD, Mean symptoms duration was 15.01 months±9.32 SD. Common presenting symptoms were backache (77.1%), lower limbs pain (66.1%), dermatomal paresthesias (54.1%) and neurogenic claudication in 57.8% patients. The mean visual analogue score (VAS) after injection was 3.18±1.29 while mean ODI after injection was 23.615. There was a statistically significant reduction in VAS scores (2-sided p=0.003, OR =4.03, 95% CI: 1.535-10.60) following the injection., Conclusions: An epidural spinal injection is a viable option for achieving relief of pain & improves functioning in individuals with radicular backache. However, further research is advised in order to clarify the role of ESI for long-term relief.

Published
2016

24. CLINICAL FEATURES AND OUTCOME ANALYSIS OF INTRACRANIAL HYDATID CYSTS.

Author

Khan MM, Shah M, Khan AA, ur Rehman R, Ayub S, Ahmad A, Aman A, and Shah MA

Subjects
Adolescent, Adult, Child, Echinococcosis diagnosis, Female, Headache etiology, Humans, Male, Papilledema etiology, Prospective Studies, Seizures etiology, Vomiting etiology, Young Adult, Brain Diseases parasitology, Brain Diseases surgery, Echinococcosis surgery, Glasgow Outcome Scale
Abstract

Background: Hydatid cyst of the brain is serious zoonotic parasitic infections which have profound health consequences if left untreated. The surgical excisions of the cysts are rewarding for both the patient the neurosurgeon., Methods: The study was conducted prospectively at Department of Neurosurgery Hayatabad Medical Complex Peshawar from January 2013 to December 2014. Patients with a diagnosis of intracranial hydatid cysts were included, clinical and radiological features recorded, intervention and postoperative outcome were analysed., Results: Eleven patients with a male to female ratio of 1.7:1. Mean age was 12.4 (SD ± 6.5) years with median GCS on arrival of 10 (SD ± 2.5). Clinical features were headache (81.8%), vomiting (90.9%), seizures (36.4%), focal deficits (54.5%) and papilloedema (72.7%). The median GCS on discharge was 13 (SD ± 1.1) while GOS at 1 month follow up was 4 (SD ± 0.7). The bivariate analysis showed inverse correlation (R² = -0.68; p = 0.02) between duration of symptoms and outcome while GCS on admission was positively correlated (r(s) = 0.75; p = 0.007) with the outcome. There was no mortality., Conclusion: Despite its rarity the clinical features are non-specific while radiological features help in establishing diagnosis. Earlier diagnosis and prompt intervention is the key to favourable outcome.

Published
2016

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