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Background: Schwannomas are usually benign tumors that arise from the schwann cells in the neural sheaths of peripheral nerves. Most schwannomas occur in the head, neck, or limbs and rarely in the retroperitoneal space. In the retroperitoneal space, schwannomas are most commonly located near the adrenal gland. We report a successfully resected retroperitoneal benign schwannoma near the inferior vena cava (IVC) using laparoscopic surgery., Methods/results: A 33-year-old woman presented with dull abdominal pain for several months. Magnetic resonance imaging confirmed the existence of a round, sharply demarcated retroperitoneal solid tumor, 42 x 52 mm in size, located between the anterior of the right kidney and the IVC, which was compressed but still patent. The lesion was laparoscopically resected, and pathologic examination revealed a degenerative schwannoma., Conclusion: Laparoscopic surgery is very useful and feasible in the diagnosis and treatment of retroperitoneal schwannoma, with minimal invasiveness and early postoperative recovery., (Copyright 2010 Annals of Vascular Surgery Inc. Published by Elsevier Inc. All rights reserved.)

Background/purpose: Portal vein embolization is used in the treatment of hepatocellular cancer, with the purpose of enhancing resectability. However, regeneration is restricted due to hepatocellular injury following chemotherapeutics (e.g. doxorubicin). The aim of this study was to investigate whether hyperbaric oxygenation (HBO) can alleviate the hepatotoxicity of chemotherapy and improve regeneration in the injured liver., Methods: Rats were allocated to four experimental groups. Group I rats were subjected to right portal vein ligation (RPVL); rats in groups II and III were administered doxorubicin prior to RPVL, with group III rats being additionally exposed to HBO sessions postoperatively; group IV rats was sham-operated. All rats were sacrificed on postoperative day 7, and liver injury was assessed by measuring alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Protein synthetic ability was determined based albumin levels and liver regeneration by the mitotic index (MI)., Results: The AST and ALT values of group II rats were significantly higher than those of group I, but not those of group III. Rats treated with doxorubicin and HBO (groups II and III) showed slightly but not significant differences in albumin levels than those subjected to only RPVL or sham-operated. The MI was significantly increased in groups I, II, and III, with the MI of group III rats significantly higher than those of group I rats., Conclusions: Based on our results, we conclude that HBO treatment has the potential to diminish doxorubicin-related hepatotoxicity and improve regeneration in the injured liver.