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145 results on '"Kwon, Hyung-Joon"'

1. Logical Pseudocode: Connecting Algorithms with Proofs

Author

Kwon, Keehang and Kwon, Hyung Joon

Subjects
Computer Science - Logic in Computer Science
Abstract

Proofs (sequent calculus, natural deduction) and imperative algorithms (pseudocodes) are two well-known coexisting concepts. Then what is their relationship? Our answer is that \[ imperative\ algorithms\ =\ proofs\ with\ cuts \] This observation leads to a generalization to pseudocodes which we call {\it logical pseudocodes}. It is similar to natural deduction proof of computability logic\cite{Jap03,Jap08}. Each statement in it corresponds to a proof step in natural deduction. Therefore, the merit over pseudocode is that each statement is guaranteed to be correct and safe with respect to the initial specifications. It can also be seen as an extension to computability logic web (\colw) with forward reasoning capability., Comment: 4 pages. Induction is missing in version 1 but added in version 2. arXiv admin note: text overlap with arXiv:2108.10728

Published
2022

5. Integrated proteogenomic characterization of glioblastoma evolution

Author

Kim, Kyung-Hee, Migliozzi, Simona, Koo, Harim, Hong, Jun-Hee, Park, Seung Min, Kim, Sooheon, Kwon, Hyung Joon, Ha, Seokjun, Garofano, Luciano, Oh, Young Taek, D'Angelo, Fulvio, Kim, Chan Il, Kim, Seongsoo, Lee, Ji Yoon, Kim, Jiwon, Hong, Jisoo, Jang, Eun-Hae, Mathon, Bertrand, Di Stefano, Anna-Luisa, Bielle, Franck, Laurenge, Alice, Nesvizhskii, Alexey I., Hur, Eun-Mi, Yin, Jinlong, Shi, Bingyang, Kim, Youngwook, Moon, Kyung-Sub, Kwon, Jeong Taik, Lee, Shin Heon, Lee, Seung Hoon, Gwak, Ho Shin, Lasorella, Anna, Yoo, Heon, Sanson, Marc, Sa, Jason K., Park, Chul-Kee, Nam, Do-Hyun, Iavarone, Antonio, and Park, Jong Bae

Published
2024
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6. Enhanced virulence and waning vaccine-elicited antibodies account for breakthrough infections caused by SARS-CoV-2 delta and beyond

Author

Kwon, Hyung-Joon, Kosikova, Martina, Tang, Weichun, Ortega-Rodriguez, Uriel, Radvak, Peter, Xiang, Ruoxuan, Mercer, Kelly E., Muskhelishvili, Levan, Davis, Kelly, Ward, Jerrold M., Kosik, Ivan, Holly, Jaroslav, Kang, Insung, Yewdell, Jonathan W., Plant, Ewan P., Chen, Wilbur H., Shriver, Mallory C., Barnes, Robin S., Pasetti, Marcela F., Zhou, Bin, Wentworth, David E., and Xie, Hang

Published
2022
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7. HPK1 Dysregulation‐Associated NK Cell Dysfunction and Defective Expansion Promotes Metastatic Melanoma Progression.

Author

Choi, Woo Seon, Kwon, Hyung‐Joon, Yi, Eunbi, Lee, Haeun, Kim, Jung Min, Park, Hyo Jin, Choi, Eun Ji, Choi, Myoung Eun, Sung, Young Hoon, Won, Chong Hyun, Sung, Chang Ohk, and Kim, Hun Sik

Subjects
*KILLER cells, *IMMUNE checkpoint proteins, *CYTOTOXINS, *TUMOR growth, *IMMUNE response
Abstract

Distant metastasis, the leading cause of cancer death, is efficiently kept in check by immune surveillance. Studies have uncovered peripheral natural killer (NK) cells as key antimetastatic effectors and their dysregulation during metastasis. However, the molecular mechanism governing NK cell dysfunction links to metastasis remains elusive. Herein, MAP4K1 encoding HPK1 is aberrantly overexpressed in dysfunctional NK cells in the periphery and the metastatic site. Conditional HPK1 overexpression in NK cells suffices to exacerbate melanoma lung metastasis but not primary tumor growth. Conversely, MAP4K1‐deficient mice are resistant to metastasis and further protected by combined immune‐checkpoint inhibitors. Mechanistically, HPK1 restrains NK cell cytotoxicity and expansion via activating receptors. Likewise, HPK1 limits human NK cell activation and associates with melanoma NK cell dysfunction couples to TGF‐β1 and patient response to immune checkpoint therapy. Thus, HPK1 is an intracellular checkpoint controlling NK‐target cell responses, which is dysregulated and hijacked by tumors during metastatic progression. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Fam20C Kinase as A Key Regulator of Bevacizumab Resistance in Mesenchymal Glioblastoma

Author

Kim, Chan Il, primary, Kim, Sooheon, additional, Park, Seong‐Min, additional, Kim, Sung Soo, additional, Kwon, Hyung Joon, additional, Lin, Weiwei, additional, Park, Saewhan, additional, Ha, Seokjun, additional, Ha, Kyung Hee, additional, Park, Sanha, additional, Park, Seung Min, additional, Kim, Tae Hoon, additional, Kim, Kyung‐Hee, additional, Kim, Yun‐Hee, additional, Kim, Jong Heon, additional, and Park, Jong Bae, additional

Published
2023
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9. Monoclonal Antibodies as SARS-CoV-2 Serology Standards: Experimental Validation and Broader Implications for Correlates of Protection

Author

Wang, Lili, primary, Patrone, Paul N., additional, Kearsley, Anthony J., additional, Izac, Jerilyn R., additional, Gaigalas, Adolfas K., additional, Prostko, John C., additional, Kwon, Hyung Joon, additional, Tang, Weichun, additional, Kosikova, Martina, additional, Xie, Hang, additional, Tian, Linhua, additional, Elsheikh, Elzafir B., additional, Kwee, Edward J., additional, Kemp, Troy, additional, Jochum, Simon, additional, Thornburg, Natalie, additional, McDonald, L. Clifford, additional, Gundlapalli, Adi V., additional, and Lin-Gibson, Sheng, additional

Published
2023
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13. CAMEL NANOBODIES NEUTRALIZE SARS-COV-2 VARIANTS

Author

Hong, Jessica, primary, Kwon, Hyung Joon, additional, Cachau, Raul, additional, Butay, Kevin John, additional, Duan, Zhijian, additional, Li, Dan, additional, Ren, Hua, additional, Hsieh, Chao-Ming, additional, Dandey, Venkata P, additional, Borgnia, Mario J, additional, Xie, Hang, additional, and Ho, Mitchell, additional

Published
2023
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15. Data from Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling

Author

Yin, Jinlong, primary, Oh, Young Taek, primary, Kim, Jeong-Yub, primary, Kim, Sung Soo, primary, Choi, Eunji, primary, Kim, Tae Hoon, primary, Hong, Jun Hee, primary, Chang, Nakho, primary, Cho, Hee Jin, primary, Sa, Jason K., primary, Kim, Jeong Cheol, primary, Kwon, Hyung Joon, primary, Park, Saewhan, primary, Lin, Weiwei, primary, Nakano, Ichiro, primary, Gwak, Ho-Shin, primary, Yoo, Heon, primary, Lee, Seung-Hoon, primary, Lee, Jeongwu, primary, Kim, Jong Heon, primary, Kim, Soo-Youl, primary, Nam, Do-Hyun, primary, Park, Myung-Jin, primary, and Park, Jong Bae, primary

Published
2023
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16. Supplementary Figure 1-3 from Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling

Author

Yin, Jinlong, primary, Oh, Young Taek, primary, Kim, Jeong-Yub, primary, Kim, Sung Soo, primary, Choi, Eunji, primary, Kim, Tae Hoon, primary, Hong, Jun Hee, primary, Chang, Nakho, primary, Cho, Hee Jin, primary, Sa, Jason K., primary, Kim, Jeong Cheol, primary, Kwon, Hyung Joon, primary, Park, Saewhan, primary, Lin, Weiwei, primary, Nakano, Ichiro, primary, Gwak, Ho-Shin, primary, Yoo, Heon, primary, Lee, Seung-Hoon, primary, Lee, Jeongwu, primary, Kim, Jong Heon, primary, Kim, Soo-Youl, primary, Nam, Do-Hyun, primary, Park, Myung-Jin, primary, and Park, Jong Bae, primary

Published
2023
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21. Structural and functional characteristics of SARS-CoV-2 Omicron subvariant BA.2 spike

Author

Zhang, Jun, primary, Tang, Weichun, additional, Gao, Hailong, additional, Lavine, Christy L., additional, Shi, Wei, additional, Peng, Hanqin, additional, Zhu, Haisun, additional, Anand, Krishna, additional, Kosikova, Matina, additional, Kwon, Hyung Joon, additional, Tong, Pei, additional, Gautam, Avneesh, additional, Rits-Volloch, Sophia, additional, Wang, Shaowei, additional, Mayer, Megan L., additional, Wesemann, Duane R., additional, Seaman, Michael S., additional, Lu, Jianming, additional, Xiao, Tianshu, additional, Xie, Hang, additional, and Chen, Bing, additional

Published
2022
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22. Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants

Author

Hong, Jessica, primary, Kwon, Hyung Joon, additional, Cachau, Raul, additional, Chen, Catherine Z., additional, Butay, Kevin John, additional, Duan, Zhijian, additional, Li, Dan, additional, Ren, Hua, additional, Liang, Tianyuzhou, additional, Zhu, Jianghai, additional, Dandey, Venkata P., additional, Martin, Negin P., additional, Esposito, Dominic, additional, Ortega-Rodriguez, Uriel, additional, Xu, Miao, additional, Borgnia, Mario J., additional, Xie, Hang, additional, and Ho, Mitchell, additional

Published
2022
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25. Camel nanobodies broadly neutralize SARS-CoV-2 variants

Author

Hong, Jessica, primary, Kwon, Hyung Joon, additional, Cachau, Raul, additional, Chen, Catherine Z., additional, Butay, Kevin John, additional, Duan, Zhijian, additional, Li, Dan, additional, Ren, Hua, additional, Liang, Tianyuzhou, additional, Zhu, Jianghai, additional, Dandey, Venkata P., additional, Martin, Negin, additional, Esposito, Dominic, additional, Ortega-Rodriguez, Uriel, additional, Xu, Miao, additional, Borgnia, Mario J., additional, Xie, Hang, additional, and Ho, Mitchell, additional

Published
2021
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28. B.1.1.7 and B.1.351 variants are highly virulent in K18-ACE2 transgenic mice and show different pathogenic patterns from early SARS-CoV-2 strains

Author

Radvak, Peter, primary, Kwon, Hyung Joon, additional, Kosikova, Martina, additional, Ortega-Rodriguez, Uriel, additional, Xiang, Ruoxuan, additional, Phue, Je-Nie, additional, Shen, Rong-Fong, additional, Rozzelle, James, additional, Kapoor, Neeraj, additional, Rabara, Taylor, additional, Fairman, Jeff, additional, and Xie, Hang, additional

Published
2021
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31. SARS-CoV-2 show no infectivity at later stages in a prolonged COVID-19 patient despite positivity in RNA testing

Author

Wan, Xiu-Feng, primary, Tang, Cynthia Y., additional, Ritter, Detlef, additional, Wang, Yang, additional, Li, Tao, additional, Segovia, Karen, additional, Kosikova, Martina, additional, Johnson, Marc, additional, Kwon, Hyung Joon, additional, Xie, Hang, additional, Hammer, Richard D., additional, McElroy, Jane A., additional, Hamid, Aws, additional, Collins, Natalie D, additional, Hang, Jun, additional, and Camp, Simone, additional

Published
2021
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32. Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma

Author

Hong, Jun-Hee, primary, Kang, Sangjo, additional, Sa, Jason K, additional, Park, Gunwoo, additional, Oh, Young Taek, additional, Kim, Tae Hoon, additional, Yin, Jinlong, additional, Kim, Sung Soo, additional, D’Angelo, Fulvio, additional, Koo, Harim, additional, You, Yeonhee, additional, Park, Saewhan, additional, Kwon, Hyung Joon, additional, Kim, Chan Il, additional, Ryu, Haseo, additional, Lin, Weiwei, additional, Park, Eun Jung, additional, Kim, Youn-Jae, additional, Park, Myung-Jin, additional, Kim, Hyunggee, additional, Kim, Mi-Suk, additional, Chung, Seok, additional, Park, Chul-Kee, additional, Park, Sung-Hye, additional, Kang, Yun Hee, additional, Kim, Jong Heon, additional, Saya, Hideyuki, additional, Nakano, Ichiro, additional, Gwak, Ho-Shin, additional, Yoo, Heon, additional, Lee, Jeongwu, additional, Hur, Eun-Mi, additional, Shi, Bingyang, additional, Nam, Do-Hyun, additional, Iavarone, Antonio, additional, Lee, Seung-Hoon, additional, and Park, Jong Bae, additional

Published
2021
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33. Endogenous DEL-1 restrains melanoma lung metastasis by limiting myeloid cell–associated lung inflammation

Author

Hyun, Young-Min, primary, Seo, Sang-Uk, additional, Choi, Woo Seon, additional, Kwon, Hyung-Joon, additional, Kim, Dong-Young, additional, Jeong, Soi, additional, Kang, Gyeong-Yi, additional, Yi, Eunbi, additional, Kim, Minjung, additional, Ryu, Hyun Jin, additional, Looney, Mark R., additional, Choi, Eun Young, additional, and Kim, Hun Sik, additional

Published
2020
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35. ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages

Author

Yin, Jinlong, primary, Kim, Sung Soo, additional, Choi, Eunji, additional, Oh, Young Taek, additional, Lin, Weiwei, additional, Kim, Tae-Hoon, additional, Sa, Jason K., additional, Hong, Jun Hee, additional, Park, Se Hwan, additional, Kwon, Hyung Joon, additional, Jin, Xiong, additional, You, Yeonhee, additional, Kim, Ji Hye, additional, Kim, Hyunggee, additional, Son, Jaekyoung, additional, Lee, Jeongwu, additional, Nam, Do-Hyun, additional, Choi, Kui Son, additional, Shi, Bingyang, additional, Gwak, Ho-Shin, additional, Yoo, Heon, additional, Iavarone, Antonio, additional, Kim, Jong Heon, additional, and Park, Jong Bae, additional

Published
2020
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36. A new division algorithm based on lookahead of partial-remainder (LAPR) for high-speed/low-power coding applications

Author

Kwon, Hyung-Joon and Lee, Kwyro

Subjects
Algorithms -- Research, Approximation theory -- Research, Coding theory -- Research, Business, Computers and office automation industries, Electronics, Electronics and electrical industries
Abstract

A new polynomial division algorithm in finite field GF([2.sup.m]) based on the lookahead of partial-remainder (LAPR) is proposed. Since our algorithm is based on partial division on group basis and lookahead technique exploiting the linearity in finite field arithmetic, it is possible to completely eliminate polynomial multiplications leading to highly increased throughput per unit time. The inherent regularity and feedforward nature of our algorithm make it possible to be fully pipelined. When pipelined, its throughput is one quotient and one remainder per clock cycle, regardless of the degree of dividend polynomial, which is orders of magnitude faster than the conventional architecture using linear feedback shift register. An area-efficient sequential architecture based on LAPR is also presented. Although the throughput rate of sequential architecture is lower than that of the pipelined one, it is still higher than that of any division architecture ever reported. Those will be shown to be efficient, regular, and easily expandable, and hence, naturally suitable for very large scale integration implementation. In systems requiring modest speed, the high-speed nature of our proposed architecture can be traded for low-power consumption by reducing clock rate. We verified the general validity of the division algorithm based on LAPR by mathematical manipulation and simulation. The superiority of our proposed architecture compared with other reported ones is demonstrated with regard to its throughput, latency delays, and power. Index Terms - Author, please supply index terms. E-mail keywords@ieee.org for info.

Published
1999

41. Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling

Author

Yin, Jinlong, primary, Oh, Young Taek, additional, Kim, Jeong-Yub, additional, Kim, Sung Soo, additional, Choi, Eunji, additional, Kim, Tae Hoon, additional, Hong, Jun Hee, additional, Chang, Nakho, additional, Cho, Hee Jin, additional, Sa, Jason K., additional, Kim, Jeong Cheol, additional, Kwon, Hyung Joon, additional, Park, Saewhan, additional, Lin, Weiwei, additional, Nakano, Ichiro, additional, Gwak, Ho-Shin, additional, Yoo, Heon, additional, Lee, Seung-Hoon, additional, Lee, Jeongwu, additional, Kim, Jong Heon, additional, Kim, Soo-Youl, additional, Nam, Do-Hyun, additional, Park, Myung-Jin, additional, and Park, Jong Bae, additional

Published
2017
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44. NK cell function triggered by multiple activating receptors is negatively regulated by glycogen synthase kinase-3β

Author

Kwon, Hyung-Joon, primary, Kwon, Soon Jae, additional, Lee, Heejae, additional, Park, Hye-Ran, additional, Choi, Go-Eun, additional, Kang, Sang-Wook, additional, Kwon, Seog Woon, additional, Kim, Nacksung, additional, Lee, Soo Young, additional, Ryu, Sangryeol, additional, Kim, Sun Chang, additional, and Kim, Hun Sik, additional

Published
2015
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