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Your search keyword '"La, Nghi"' showing total 12 results
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12 results on '"La, Nghi"'

1. Battery metal recycling by flash Joule heating

Author

Chen, Weiyin, primary, Chen, Jinhang, additional, Bets, Ksenia V., additional, Salvatierra, Rodrigo V., additional, Wyss, Kevin M., additional, Gao, Guanhui, additional, Choi, Chi Hun, additional, Deng, Bing, additional, Wang, Xin, additional, Li, John Tianci, additional, Kittrell, Carter, additional, La, Nghi, additional, Eddy, Lucas, additional, Scotland, Phelecia, additional, Cheng, Yi, additional, Xu, Shichen, additional, Li, Bowen, additional, Tomson, Mason B., additional, Han, Yimo, additional, Yakobson, Boris I., additional, and Tour, James M., additional

Published
2023
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2. Flash Recycling of Graphite Anodes

Author

Chen, Weiyin, primary, Salvatierra, Rodrigo V., additional, Li, John Tianci, additional, Kittrell, Carter, additional, Beckham, Jacob L., additional, Wyss, Kevin M., additional, La, Nghi, additional, Savas, Paul E., additional, Ge, Chang, additional, Advincula, Paul A., additional, Scotland, Phelecia, additional, Eddy, Lucas, additional, Deng, Bing, additional, Yuan, Zhe, additional, and Tour, James M., additional

Published
2022
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3. Brushed Metals for Rechargeable Metal Batteries

Author

Chen, Weiyin, primary, Salvatierra, Rodrigo V., additional, Li, John T., additional, Luong, Duy X., additional, Beckham, Jacob L., additional, Li, Victor D., additional, La, Nghi, additional, Xu, Jianan, additional, and Tour, James M., additional

Published
2022
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5. Flash Recycling of Graphite Anodes.

Author

Chen, Weiyin, Salvatierra, Rodrigo V., Li, John Tianci, Kittrell, Carter, Beckham, Jacob L., Wyss, Kevin M., La, Nghi, Savas, Paul E., Ge, Chang, Advincula, Paul A., Scotland, Phelecia, Eddy, Lucas, Deng, Bing, Yuan, Zhe, and Tour, James M.

Published
2023
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8. Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid

Author

Tarrant, Jacqueline M., primary, Dhawan, Preeti, additional, Singh, Jatinder, additional, Zabka, Tanja S., additional, Clarke, Emer, additional, DosSantos, Garry, additional, Dragovich, Peter S., additional, Sampath, Deepak, additional, Lin, Tori, additional, McCray, Bobbi, additional, La, Nghi, additional, Nguyen, Trung, additional, Kauss, Ariel, additional, Dambach, Donna, additional, Misner, Dinah L., additional, Diaz, Dolores, additional, and Uppal, Hirdesh, additional

Published
2015
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9. Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy

Author

Leverson, Joel D., primary, Phillips, Darren C., additional, Mitten, Michael J., additional, Boghaert, Erwin R., additional, Diaz, Dolores, additional, Tahir, Stephen K., additional, Belmont, Lisa D., additional, Nimmer, Paul, additional, Xiao, Yu, additional, Ma, Xiaoju Max, additional, Lowes, Kym N., additional, Kovar, Peter, additional, Chen, Jun, additional, Jin, Sha, additional, Smith, Morey, additional, Xue, John, additional, Zhang, Haichao, additional, Oleksijew, Anatol, additional, Magoc, Terrance J., additional, Vaidya, Kedar S., additional, Albert, Daniel H., additional, Tarrant, Jacqueline M., additional, La, Nghi, additional, Wang, Le, additional, Tao, Zhi-Fu, additional, Wendt, Michael D., additional, Sampath, Deepak, additional, Rosenberg, Saul H., additional, Tse, Chris, additional, S. Huang, David C., additional, Fairbrother, Wayne J., additional, Elmore, Steven W., additional, and Souers, Andrew J., additional

Published
2015
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10. Retinal Toxicity, in vivo and in vitro, Associated with Inhibition of Nicotinamide Phosphoribosyltransferase

Author

Zabka, Tanja S., primary, Singh, Jatinder, additional, Dhawan, Preeti, additional, Liederer, Bianca M., additional, Oeh, Jason, additional, Kauss, Mara A., additional, Xiao, Yang, additional, Zak, Mark, additional, Lin, Tori, additional, McCray, Bobbi, additional, La, Nghi, additional, Nguyen, Trung, additional, Beyer, Joseph, additional, Farman, Cynthia, additional, Uppal, Hirdesh, additional, Dragovich, Peter S., additional, O’Brien, Thomas, additional, Sampath, Deepak, additional, and Misner, Dinah L., additional

Published
2014
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11. MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats.

Author

Diaz, Dolores, Cain, Gary, La, Nghi, Dambach, Donna, Schwartz, Jacob, Pai, Rama, and Tarrant, Jacqueline M.

Subjects
MITOGEN-activated protein kinases, EXTRACELLULAR signal-regulated kinases, CERULOPLASMIN
Abstract

Inhibition of the mitogen-activated protein kinase/extracellular signal-regulated (MAPK/ERK) pathway is an attractive therapeutic approach for human cancer therapy. In the course of evaluating structurally distinct small molecule inhibitors that target mitogen-activated protein kinase kinase (MEK) and ERK kinases in this pathway, we observed an unusual, dose-related increase in the incidence of green serum in preclinical safety studies in rats. Having ruled out changes in bilirubin metabolism, we demonstrated a 2- to 3-fold increase in serum ceruloplasmin levels, likely accounting for the observed green color. This was not associated with an increase in α-2-macroglobulin, the major acute phase protein in rats, indicating that ceruloplasmin levels increased independently of an inflammatory response. Elevated serum ceruloplasmin was also not correlated with changes in total hepatic copper, adverse clinical signs, or pathology findings indicative of copper toxicity, therefore discounting copper overload as the etiology. Both ERK and MEK inhibitors led to increased ceruloplasmin secretion in rat primary hepatocyte cultures in vitro, and this increase was associated with activation of the Forkhead box, class O1 (FOXO1) transcription factor. In conclusion, increased serum ceruloplasmin induced by MEK and ERK inhibition is due to increased synthesis by hepatocytes from FOXO1 activation and results in the nonadverse development of green serum in rats. [ABSTRACT FROM AUTHOR]

Published
2017
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12. Phosphorous Dysregulation Induced by MEK Small Molecule Inhibitors in the Rat Involves Blockade of FGF-23 Signaling in the Kidney

Author

Diaz, Dolores, primary, Allamneni, Krishna, additional, Tarrant, Jacqueline M., additional, Lewin-Koh, Sock-Cheng, additional, Pai, Rama, additional, Dhawan, Preeti, additional, Cain, Gary R., additional, Kozlowski, Cleopatra, additional, Hiraragi, Hajime, additional, La, Nghi, additional, Hartley, Dylan P., additional, Ding, Xiao, additional, Dean, Brian J., additional, Bheddah, Sheila, additional, and Dambach, Donna M., additional

Published
2011
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