128 results on '"Maglietta, Giuseppe"'
Search Results
2. The role of blood cholesterol quality in patients with advanced cancer receiving immune checkpoint inhibitors
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Perrone, Fabiana, Favari, Elda, Maglietta, Giuseppe, Verzè, Michela, Pluchino, Monica, Minari, Roberta, Sabato, Roberto, Mazzaschi, Giulia, Ronca, Annalisa, Rossi, Alessandra, Cortellini, Alessio, Pecci, Federica, Cantini, Luca, Bersanelli, Melissa, Quaini, Federico, Tiseo, Marcello, and Buti, Sebastiano
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- 2023
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3. Real-world outcomes of Italian patients with advanced non-squamous lung cancer treated with first-line pembrolizumab plus platinum-pemetrexed
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Leonetti, Alessandro, Perrone, Fabiana, Puntoni, Matteo, Maglietta, Giuseppe, Bordi, Paola, Bria, Emilio, Vita, Emanuele, Gelsomino, Francesco, De Giglio, Andrea, Gelibter, Alain, Siringo, Marco, Mazzoni, Francesca, Caliman, Enrico, Genova, Carlo, Bertolini, Federica, Guaitoli, Giorgia, Passiglia, Francesco, Delcuratolo, Marco Donatello, Montrone, Michele, Cerea, Giulio, Pasello, Giulia, Roca, Elisa, Belluomini, Lorenzo, Cecere, Fabiana Letizia, Guida, Annalisa, Manzo, Anna, Adamo, Vincenzo, Rastelli, Francesca, Bulotta, Alessandra, Citarella, Fabrizio, Toschi, Luca, Zoratto, Federica, Cortinovis, Diego Luigi, Berardi, Rossana, Follador, Alessandro, Carta, Annamaria, Camerini, Andrea, Salerno, Flavio, Silva, Rosa Rita, Baldini, Editta, Cortellini, Alessio, Brighenti, Matteo, Santoni, Matteo, Malorgio, Francesco, Caminiti, Caterina, and Tiseo, Marcello
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- 2024
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4. Pattern of recurrence in endometrial cancer. The murderer always returns to the scene of the crime
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Capozzi, Vito Andrea, Monfardini, Luciano, Maglietta, Giuseppe, Barresi, Giuseppe, De Finis, Alessandra, Rosati, Andrea, Vargiu, Virginia, Cosentino, Francesco, Sozzi, Giulio, Chiantera, Vito, Bogani, Giorgio, Carnelli, Marco, Scambia, Giovanni, Fanfani, Francesco, Ghi, Tullio, and Berretta, Roberto
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- 2024
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5. Hysteroscopic endometrial tumor localization and sentinel lymph node mapping. An upgrade of the hysteroscopic role in endometrial cancer patients
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Capozzi, Vito Andrea, Armano, Giulia, Maglietta, Giuseppe, Rosati, Andrea, Vargiu, Virginia, Scarpelli, Elisa, Sozzi, Giulio, Chiantera, Vito, Cosentino, Francesco, Gioè, Alessandro, Catena, Ursula, Scambia, Giovanni, Fanfani, Francesco, Di Spiezio Sardo, Attilio, Ghi, Tullio, and Berretta, Roberto
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- 2023
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6. Levothyroxine-induced serum free thyroxine response following radioactive iodine administration in patients thyroidectomized for differentiated thyroid cancer: A randomized controlled trial
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Marina, Michela, Maglietta, Giuseppe, De Filpo, Giuseppina, Aloe, Rosalia, Gnocchi, Cecilia, Iezzi, Elisa, Caminiti, Caterina, and Ceresini, Graziano
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- 2022
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7. Long-term outcomes of early-onset myocardial infarction with non-obstructive coronary artery disease (MINOCA)
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Magnani, Giulia, Bricoli, Serena, Ardissino, Maddalena, Maglietta, Giuseppe, Nelson, Adam, Malagoli Tagliazucchi, Guidantonio, Disisto, Caterina, Celli, Patrizia, Ferrario, Maurizio, Canosi, Umberto, Cernetti, Carlo, Negri, Francesco, Merlini, Piera Angelica, Tubaro, Marco, Berzuini, Carlo, Manzalini, Chiara, Ignone, Gianfranco, Campana, Carlo, Moschini, Luigi, Ponte, Elisabetta, Pozzi, Roberto, Fetiveau, Raffaela, Buratti, Silvia, Paraboschi, Elvezia, Asselta, Rosanna, Botti, Andrea, Tuttolomondo, Domenico, Barocelli, Federico, Biagi, Andrea, Bonura, Rosario, Moccetti, Tiziano, Crocamo, Antonio, Benatti, Giorgio, Paoli, Giorgia, Solinas, Emilia, Notarangelo, Maria Francesca, Moscarella, Elisabetta, Calabrò, Paolo, Duga, Stefano, Niccoli, Giampaolo, and Ardissino, Diego
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- 2022
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8. Intersecting Blood Cytokines With Cholesterol Parameters to Profile Patients With Advanced Solid Tumors Receiving Immune Checkpoint Inhibitors.
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Mazzaschi, Giulia, Perrone, Fabiana, Maglietta, Giuseppe, Favari, Elda, Verzè, Michela, Pluchino, Monica, Minari, Roberta, Pecci, Federica, Gnetti, Letizia, Campanini, Nicoletta, Silini, Enrico Maria, De Filippo, Massimo, Maffezzoli, Michele, Giudice, Giulia Claire, Testi, Irene, Tiseo, Marcello, Quaini, Federico, and Buti, Sebastiano
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- 2024
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9. Sudden cardiac death after early-onset myocardial infarction: a multicentre longitudinal cohort study with a 20-year follow-up
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Bricoli, Serena, Magnani, Giulia, Ardissino, Maddalena, Maglietta, Giuseppe, Celli, Patrizia, Ferrario, Maurizio, Canosi, Umberto, Cernetti, Carlo, Negri, Francesco, Merlini, Piera Angelica, Tubaro, Marco, Berzuini, Carlo, Manzalini, Chiara, Moschini, Luigi, Ponte, Elisabetta, Pozzi, Roberto, Buratti, Silvia, Botti, Andrea, Barocelli, Federico, Biagi, Andrea, Bonura, Rosario, Bearzot, Luca, Moccetti, Tiziano, Crocamo, Antonio, Notarangelo, Maria Francesca, Moscarella, Elisabetta, Calabrò, Paolo, Niccoli, Giampaolo, and Ardissino, Diego
- Abstract
Graphical AbstractSudden cardiac death after early-onset myocardial infarction. MI, myocardial infarction; SCD, sudden cardiac death.
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- 2024
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10. Real-world outcomes of Italian patients with advanced non-squamous lung cancer treated with first-line pembrolizumab plus platinum-pemetrexed
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Leonetti, A, Perrone, F, Puntoni, M, Maglietta, G, Bordi, P, Bria, E, Vita, E, Gelsomino, F, De Giglio, A, Gelibter, A, Siringo, M, Mazzoni, F, Caliman, E, Genova, C, Bertolini, F, Guaitoli, G, Passiglia, F, Delcuratolo, M, Montrone, M, Cerea, G, Pasello, G, Roca, E, Belluomini, L, Cecere, F, Guida, A, Manzo, A, Adamo, V, Rastelli, F, Bulotta, A, Citarella, F, Toschi, L, Zoratto, F, Cortinovis, D, Berardi, R, Follador, A, Carta, A, Camerini, A, Salerno, F, Silva, R, Baldini, E, Cortellini, A, Brighenti, M, Santoni, M, Malorgio, F, Caminiti, C, Tiseo, M, Leonetti, Alessandro, Perrone, Fabiana, Puntoni, Matteo, Maglietta, Giuseppe, Bordi, Paola, Bria, Emilio, Vita, Emanuele, Gelsomino, Francesco, De Giglio, Andrea, Gelibter, Alain, Siringo, Marco, Mazzoni, Francesca, Caliman, Enrico, Genova, Carlo, Bertolini, Federica, Guaitoli, Giorgia, Passiglia, Francesco, Delcuratolo, Marco Donatello, Montrone, Michele, Cerea, Giulio, Pasello, Giulia, Roca, Elisa, Belluomini, Lorenzo, Cecere, Fabiana Letizia, Guida, Annalisa, Manzo, Anna, Adamo, Vincenzo, Rastelli, Francesca, Bulotta, Alessandra, Citarella, Fabrizio, Toschi, Luca, Zoratto, Federica, Cortinovis, Diego Luigi, Berardi, Rossana, Follador, Alessandro, Carta, Annamaria, Camerini, Andrea, Salerno, Flavio, Silva, Rosa Rita, Baldini, Editta, Cortellini, Alessio, Brighenti, Matteo, Santoni, Matteo, Malorgio, Francesco, Caminiti, Caterina, Tiseo, Marcello, Leonetti, A, Perrone, F, Puntoni, M, Maglietta, G, Bordi, P, Bria, E, Vita, E, Gelsomino, F, De Giglio, A, Gelibter, A, Siringo, M, Mazzoni, F, Caliman, E, Genova, C, Bertolini, F, Guaitoli, G, Passiglia, F, Delcuratolo, M, Montrone, M, Cerea, G, Pasello, G, Roca, E, Belluomini, L, Cecere, F, Guida, A, Manzo, A, Adamo, V, Rastelli, F, Bulotta, A, Citarella, F, Toschi, L, Zoratto, F, Cortinovis, D, Berardi, R, Follador, A, Carta, A, Camerini, A, Salerno, F, Silva, R, Baldini, E, Cortellini, A, Brighenti, M, Santoni, M, Malorgio, F, Caminiti, C, Tiseo, M, Leonetti, Alessandro, Perrone, Fabiana, Puntoni, Matteo, Maglietta, Giuseppe, Bordi, Paola, Bria, Emilio, Vita, Emanuele, Gelsomino, Francesco, De Giglio, Andrea, Gelibter, Alain, Siringo, Marco, Mazzoni, Francesca, Caliman, Enrico, Genova, Carlo, Bertolini, Federica, Guaitoli, Giorgia, Passiglia, Francesco, Delcuratolo, Marco Donatello, Montrone, Michele, Cerea, Giulio, Pasello, Giulia, Roca, Elisa, Belluomini, Lorenzo, Cecere, Fabiana Letizia, Guida, Annalisa, Manzo, Anna, Adamo, Vincenzo, Rastelli, Francesca, Bulotta, Alessandra, Citarella, Fabrizio, Toschi, Luca, Zoratto, Federica, Cortinovis, Diego Luigi, Berardi, Rossana, Follador, Alessandro, Carta, Annamaria, Camerini, Andrea, Salerno, Flavio, Silva, Rosa Rita, Baldini, Editta, Cortellini, Alessio, Brighenti, Matteo, Santoni, Matteo, Malorgio, Francesco, Caminiti, Caterina, and Tiseo, Marcello
- Abstract
Purpose: The aim of this multi-center, retrospective/prospective cohort observational study was to evaluate outcomes in routine clinical practice of first-line chemo-immunotherapy with cis/carboplatin, pemetrexed and pembrolizumab in patients with advanced non-squamous non-small cell lung cancer (NSCLC) in 33 Italian centers. Methods: The outcome measure was to evaluate overall survival (OS) in a real-world patient population. Secondary endpoints were: progression-free survival (PFS), objective response rate (ORR), duration of response (DoR) and incidence of treatment-related adverse events (AEs). Results: 1068 patients were enrolled at the time of data cut-off (January 31st, 2023), and 812 (76.0%) belonged to the retrospective cohort. Median age was 66 years (27−85), ECOG PS was ≥ 2 in 91 (8.6%) patients; 254 (23.8%) patients had brain metastases at baseline; 38 (3.6%) patients had tumor with PD-L1 expression ≥ 50%. After a median follow-up of 17.0 months (95% CI, 16.1–17.9), median OS was 16.1 months (95% CI, 14.4–18.8) and PFS was 9.9 months (95% CI, 8.8–11.2). Median DoR (n = 493) was 14.7 months (95% CI, 13.6–17.1). ORR was 43.4% (95% CI, 40.4–46.4). Any-grade AEs occurred in 636 (59.6%) patients and grade ≥ 3 in 253 (23.7%) patients. Most common grade ≥ 3 AEs were neutropenia (6.3%) and anemia (6.3%). Conclusions: First-line chemo-immunotherapy was effective and tolerable in this large, real-world Italian study of patients with advanced non-squamous NSCLC. Our results were in line with the KEYNOTE-189 registration study, also considering the low number of PD-L1 ≥ 50% patients included in our study.
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- 2024
11. Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric emergency department use: a quasi-experimental study interrupted time-series analysis in North Italian hospitals, 2017 to 2022.
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Puntoni, Matteo, Maglietta, Giuseppe, Caminiti, Caterina, Miniaci, Angela, Lanari, Marcello, Caramelli, Fabio, Marchetti, Federico, De Fanti, Alessandro, Iughetti, Lorenzo, Biasucci, Giacomo, Suppiej, Agnese, Miceli, Andrea, Ghizzi, Chiara, Vergine, Gianluca, Aricò, Melodie, Stella, Marcello, and Esposito, Susanna
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- 2024
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12. Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study interrupted time-series analysis.
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Maglietta, Giuseppe, Puntoni, Matteo, Caminiti, Caterina, Pession, Andrea, Lanari, Marcello, Caramelli, Fabio, Marchetti, Federico, De Fanti, Alessandro, Iughetti, Lorenzo, Biasucci, Giacomo, Suppiej, Agnese, Miceli, Andrea, Ghizzi, Chiara, Vergine, Gianluca, Aricò, Melodie, Stella, Marcello, and Esposito, Susanna
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- 2024
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13. Role of innate and adaptive immunity in the efficacy of anti-HER2 monoclonal antibodies for HER2-positive breast cancer
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Musolino, Antonino, Boggiani, Daniela, Pellegrino, Benedetta, Zanoni, Daniele, Sikokis, Angelica, Missale, Gabriele, Silini, Enrico Maria, Maglietta, Giuseppe, Frassoldati, Antonio, and Michiara, Maria
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- 2020
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14. Procalcitonin for the diagnosis of postoperative bacterial infection after adult cardiac surgery: a systematic review and meta-analysis
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Nicolotti, Davide, primary, Grossi, Silvia, additional, Palermo, Valeria, additional, Pontone, Federico, additional, Maglietta, Giuseppe, additional, Diodati, Francesca, additional, Puntoni, Matteo, additional, Rossi, Sandra, additional, and Caminiti, Caterina, additional
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- 2024
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15. Response to the Letter re: Real-world outcomes of Italian patients with advanced non-squamous lung cancer treated with first-line pembrolizumab plus platinum-pemetrexed
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Leonetti, Alessandro, Perrone, Fabiana, Puntoni, Matteo, Maglietta, Giuseppe, Caminiti, Caterina, and Tiseo, Marcello
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- 2024
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16. Randomized, open-label, phase II, biomarker study of immune-mediated mechanism of action of neoadjuvant subcutaneous trastuzumab in patients with locally advanced, inflammatory, or early HER2-positive breast cancer—Immun-HER trial (GOIRC-01-2016)
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Pellegrino, Benedetta, primary, Tommasi, Chiara, additional, Serra, Olga, additional, Gori, Stefania, additional, Cretella, Elisabetta, additional, Ambroggi, Massimo, additional, Frassoldati, Antonio, additional, Bisagni, Giancarlo, additional, Casarini, Chiara, additional, Bria, Emilio, additional, Carbognin, Luisa, additional, Fiorio, Elena, additional, Mura, Antonella, additional, Zamagni, Claudio, additional, Gianni, Lorenzo, additional, Zambelli, Alberto, additional, Montemurro, Filippo, additional, Tognetto, Michele, additional, Todeschini, Renata, additional, Missale, Gabriele, additional, Campanini, Nicoletta, additional, Silini, Enrico Maria, additional, Maglietta, Giuseppe, additional, and Musolino, Antonino, additional
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- 2023
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17. Pharmacogenomic Approach to Selecting Antiplatelet Therapy in Patients With Acute Coronary Syndromes: The PHARMCLO Trial
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Notarangelo, Francesca Maria, Maglietta, Giuseppe, Bevilacqua, Paola, Cereda, Marco, Merlini, Piera Angelica, Villani, Giovanni Quinto, Moruzzi, Paolo, Patrizi, Giampiero, Malagoli Tagliazucchi, Guidantonio, Crocamo, Antonio, Guidorossi, Angela, Pigazzani, Filippo, Nicosia, Elisa, Paoli, Giorgia, Bianchessi, Marco, Comelli, Mario Angelo, Caminiti, Caterina, and Ardissino, Diego
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- 2018
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18. Sighting acute myocardial infarction through platelet gene expression
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Gobbi, Giuliana, Carubbi, Cecilia, Tagliazucchi, Guidantonio Malagoli, Masselli, Elena, Mirandola, Prisco, Pigazzani, Filippo, Crocamo, Antonio, Notarangelo, Maria Francesca, Suma, Sergio, Paraboschi, Elvezia, Maglietta, Giuseppe, Nagalla, Srikanth, Pozzi, Giulia, Galli, Daniela, Vaccarezza, Mauro, Fortina, Paolo, Addya, Sankar, Ertel, Adam, Bray, Paul, Duga, Stefano, Berzuini, Carlo, Vitale, Marco, and Ardissino, Diego
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- 2019
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19. Long-term survival outcomes in high-risk endometrial cancer patients undergoing sentinel lymph node biopsy alone versus lymphadenectomy
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Capozzi, Vito Andrea, primary, Rosati, Andrea, additional, Maglietta, Giuseppe, additional, Vargiu, Virginia, additional, Scarpelli, Elisa, additional, Cosentino, Francesco, additional, Sozzi, Giulio, additional, Chiantera, Vito, additional, Ghi, Tullio, additional, Scambia, Giovanni, additional, Berretta, Roberto, additional, and Fanfani, Francesco, additional
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- 2023
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20. Psychosocial Impact of Virtual Cancer Care through Technology: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
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Caminiti, Caterina, primary, Annunziata, Maria Antonietta, additional, Di Giulio, Paola, additional, Isa, Luciano, additional, Mosconi, Paola, additional, Nanni, Maria Giulia, additional, Piredda, Michela, additional, Verusio, Claudio, additional, Diodati, Francesca, additional, Maglietta, Giuseppe, additional, and Passalacqua, Rodolfo, additional
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- 2023
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21. Urologic Complication after Laparoscopic Hysterectomy in Gynecology Oncology: A Single-Center Analysis and Narrative Review of the Literature
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Capozzi, Vito Andrea, primary, Monfardini, Luciano, additional, Scarpelli, Elisa, additional, Barresi, Giuseppe, additional, Rotondella, Isabella, additional, De Finis, Alessandra, additional, Scebba, Davide, additional, Maglietta, Giuseppe, additional, Cianci, Stefano, additional, Ghi, Tullio, additional, and Berretta, Roberto, additional
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- 2022
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22. The Effects of Patient-Reported Outcome Screening on the Survival of People with Cancer: A Systematic Review and Meta-Analysis
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Caminiti, Caterina, primary, Maglietta, Giuseppe, additional, Diodati, Francesca, additional, Puntoni, Matteo, additional, Marcomini, Barbara, additional, Lazzarelli, Silvia, additional, Pinto, Carmine, additional, and Perrone, Francesco, additional
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- 2022
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23. 2022-RA-859-ESGO Long-term survival outcomes in high-risk endometrial cancer patients undergoing sentinel lymph node biopsy vs. lymphadenectomy
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Capozzi, Vito Andrea, primary, Scarpelli, Elisa, additional, Rosati, Andrea, additional, Vargiu, Virginia, additional, Sozzi, Giulio, additional, Maglietta, Giuseppe, additional, Armano, Giulia, additional, Butera, Diana, additional, Monfardini, Luciano, additional, Gaiano, Michela, additional, Celora, Gabriella, additional, Barresi, Giuseppe, additional, de Finis, Alessandra, additional, Rotondella, Isabella, additional, Chiantera, Vito, additional, Cosentino, Francesco, additional, Fanfani, Francesco, additional, Scambia, Giovanni, additional, Ghi, Tullio, additional, and Berretta, Roberto, additional
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- 2022
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24. Surgical Antimicrobial Prophylaxis in Abdominal Surgery for Neonates and Paediatrics: A RAND/UCLA Appropriateness Method Consensus Study
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Bianchini, Sonia, Rigotti, Erika, Monaco, Sara, Nicoletti, Laura, Auriti, Cinzia, Castagnola, Elio, Conti, Giorgio, Galli, Luisa, Giuffrè, Mario, La Grutta, Stefania, Lancella, Laura, Lo Vecchio, Andrea, Maglietta, Giuseppe, Petrosillo, Nicola, Pietrasanta, Carlo, Principi, Nicola, Tesoro, Simonetta, Venturini, Elisabetta, Piacentini, Giorgio, Lima, Mario, Staiano, Annamaria, Esposito, Susanna, The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, null, Bianchini S., Rigotti E., Monaco S., Nicoletti L., Auriti C., Castagnola E., Conti G., Galli L., Giuffre M., La Grutta S., Lancella L., Lo Vecchio A., Maglietta G., Petrosillo N., Pietrasanta C., Principi N., Tesoro S., Venturini E., Piacentini G., Lima M., Staiano A., Esposito S., Bianchini, Sonia, Rigotti, Erika, Monaco, Sara, Nicoletti, Laura, Auriti, Cinzia, Castagnola, Elio, Conti, Giorgio, Galli, Luisa, Giuffrè, Mario, La Grutta, Stefania, Lancella, Laura, Lo Vecchio, Andrea, Maglietta, Giuseppe, Petrosillo, Nicola, Pietrasanta, Carlo, Principi, Nicola, Tesoro, Simonetta, Venturini, Elisabetta, Piacentini, Giorgio, Lima, Mario, Staiano, Annamaria, Esposito, Susanna, and The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Null
- Subjects
Microbiology (medical) ,Infectious Diseases ,pancreas surgery ,Settore MED/41 - ANESTESIOLOGIA ,Pharmacology (medical) ,General Pharmacology, Toxicology and Pharmaceutics ,abdominal surgery ,gastrointestinal endoscopy ,Biochemistry ,Microbiology ,appendectomy ,liver surgery - Abstract
Surgical site infections (SSIs), i.e., surgery-related infections that occur within 30 days after surgery without an implant and within one year if an implant is placed, complicate surgical procedures in up to 10% of cases, but an underestimation of the data is possible since about 50% of SSIs occur after the hospital discharge. Gastrointestinal surgical procedures are among the surgical procedures with the highest risk of SSIs, especially when colon surgery is considered. Data that were collected from children seem to indicate that the risk of SSIs can be higher than in adults. This consensus document describes the use of preoperative antibiotic prophylaxis in neonates and children that are undergoing abdominal surgery and has the purpose of providing guidance to healthcare professionals who take care of children to avoid unnecessary and dangerous use of antibiotics in these patients. The following surgical procedures were analyzed: (1) gastrointestinal endoscopy; (2) abdominal surgery with a laparoscopic or laparotomy approach; (3) small bowel surgery; (4) appendectomy; (5) abdominal wall defect correction interventions; (6) ileo-colic perforation; (7) colorectal procedures; (8) biliary tract procedures; and (9) surgery on the liver or pancreas. Thanks to the multidisciplinary contribution of experts belonging to the most important Italian scientific societies that take care of neonates and children, this document presents an invaluable reference tool for perioperative antibiotic prophylaxis in the paediatric and neonatal populations.
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- 2022
25. Sex-Related Differences in Long-Term Outcomes After Early-Onset Myocardial Infarction
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Ardissino, Maddalena, primary, Nelson, Adam J., additional, Maglietta, Giuseppe, additional, Malagoli Tagliazucchi, Guidantonio, additional, Disisto, Caterina, additional, Celli, Patrizia, additional, Ferrario, Maurizio, additional, Canosi, Umberto, additional, Cernetti, Carlo, additional, Negri, Francesco, additional, Merlini, Piera Angelica, additional, Tubaro, Marco, additional, Berzuini, Carlo, additional, Manzalini, Chiara, additional, Ignone, Gianfranco, additional, Campana, Carlo, additional, Moschini, Luigi, additional, Ponte, Elisabetta, additional, Pozzi, Roberto, additional, Fetiveau, Raffaela, additional, Buratti, Silvia, additional, Paraboschi, Elvezia Maria, additional, Asselta, Rosanna, additional, Botti, Andrea, additional, Tuttolomondo, Domenico, additional, Barocelli, Federico, additional, Bricoli, Serena, additional, Biagi, Andrea, additional, Bonura, Rosario, additional, Moccetti, Tiziano, additional, Crocamo, Antonio, additional, Benatti, Giorgio, additional, Paoli, Giorgia, additional, Solinas, Emilia, additional, Notarangelo, Maria Francesca, additional, Moscarella, Elisabetta, additional, Calabrò, Paolo, additional, Duga, Stefano, additional, Magnani, Giulia, additional, and Ardissino, Diego, additional
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- 2022
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26. Phase II study of nivolumab in combination with FOLFOXIRI/bevacizumab as first-line treatment in patients with advanced colorectal cancer RAS/BRAF mutated (mut): NIVACOR trial (GOIRC-03-2018).
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Damato, Angela, primary, Bergamo, Francesca, additional, Antonuzzo, Lorenzo, additional, Nasti, Guglielmo, additional, Pietrantonio, Filippo, additional, Tonini, Giuseppe, additional, Maiello, Evaristo, additional, Bordonaro, Roberto, additional, Rosati, Gerardo, additional, Romagnani, Alessandra, additional, Iachetta, Francesco, additional, Larocca, Mario, additional, Maglietta, Giuseppe, additional, Normanno, Nicola, additional, and Pinto, Carmine, additional
- Published
- 2022
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27. Surgical Antimicrobial Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Eye Surgery: A RAND/UCLA Appropriateness Method Consensus Study
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Bianchini, Sonia, Morini, Chiara, Nicoletti, Laura, Monaco, Sara, Rigotti, Erika, Caminiti, Caterina, Conti, Giorgio, De Luca, Maia, Donà, Daniele, Maglietta, Giuseppe, Lancella, Laura, Lo Vecchio, Andrea, Marchini, Giorgio, Pietrasanta, Carlo, Principi, Nicola, Simonini, Alessandro, Venturini, Elisabetta, Longo, Anita Rosa, Gusson, Elena, Boccuzzi, Domenico, Vigo, Luca, Mosca, Fabio, Staiano, Annamaria, Esposito, Susanna, Giorgio Conti (ORCID:0000-0002-8566-9365), Rosa Longo, Bianchini, Sonia, Morini, Chiara, Nicoletti, Laura, Monaco, Sara, Rigotti, Erika, Caminiti, Caterina, Conti, Giorgio, De Luca, Maia, Donà, Daniele, Maglietta, Giuseppe, Lancella, Laura, Lo Vecchio, Andrea, Marchini, Giorgio, Pietrasanta, Carlo, Principi, Nicola, Simonini, Alessandro, Venturini, Elisabetta, Longo, Anita Rosa, Gusson, Elena, Boccuzzi, Domenico, Vigo, Luca, Mosca, Fabio, Staiano, Annamaria, Esposito, Susanna, Giorgio Conti (ORCID:0000-0002-8566-9365), and Rosa Longo
- Abstract
Ocular surgery encompasses a wide range of procedures, including surgery of the tear ducts, eyelid, cornea and conjunctiva, lens, ocular muscle, and vitreoretinal and iris surgery. Operations are also performed for the removal of tumors, repairs of ocular trauma and, finally, corneal transplantation. Antibiotic prophylaxis for the prevention of surgical site infections (SSIs) in ocular surgery is a complex field in which shared lines of action are absent. In light of the scarcity of shared evidence in the use of ocular antimicrobial prophylaxis for the pediatric population, this consensus document aims to provide clinicians with a series of recommendations on antimicrobial prophylaxis for patients of neonatal and pediatric age undergoing eye surgery. The following scenarios are considered: (1) intraocular surgery; (2) extraocular surgery; (3) ocular trauma; (4) ocular neoplasm; (5) ocular surface transplantations; (6) corneal grafts. This work has been made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies and represents, in our opinion, the most complete and up-to-date collection of recommendations regarding clinical actions in the peri-operative environment in eye surgery. The application of uniform and shared protocols aims to improve surgical practice, through the standardization of procedures, with a consequent reduction of SSIs, also limiting the phenomenon of antimicrobial resistance.
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- 2022
28. Prognostic Factors for Post-COVID-19 Syndrome: A Systematic Review and Meta-Analysis
- Author
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Maglietta, Giuseppe, primary, Diodati, Francesca, additional, Puntoni, Matteo, additional, Lazzarelli, Silvia, additional, Marcomini, Barbara, additional, Patrizi, Laura, additional, and Caminiti, Caterina, additional
- Published
- 2022
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29. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
- Author
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Abbas, Ali, Abdukahil, Sheryl Ann, Abdulkadir, Nurul Najmee, Abe, Ryuzo, Abel, Laurent, Absil, Lara, Jabal, Kamal Abu, Zayyad, Hiba Abu, Acharya, Subhash, Acker, Andrew, Adachi, Shingo, Adam, Elisabeth, Adriano, Enrico, Adrião, Diana, Ageel, Saleh Al, Ahmed, Shakeel, Aiello, Marina, Ainscough, Kate, Airlangga, Eka, Aisa, Tharwat, Hssain, Ali Ait, Tamlihat, Younes Ait, Akimoto, Takako, Akmal, Ernita, Qasim, Eman Al, Al-dabbous, Tala, Al-Fares, Abdulrahman, Alalqam, Razi, Alberti, Angela, Alegesan, Senthilkumar, Alegre, Cynthia, Alessi, Marta, Alex, Beatrice, Alexandre, Kévin, Alfoudri, Huda, Ali, Adam, Ali, Imran, Shah, Naseem Ali, Sheikh, Naseem Ali, Alidjnou, Kazali Enagnon, Aliudin, Jeffrey, Alkhafajee, Qabas, Allavena, Clotilde, Allou, Nathalie, Altaf, Aneela, Alves, João, Alves, João Melo, Alves, Rita, Amaral, Maria, Amira, Nur, Ammerlaan, Heidi, Ampaw, Phoebe, Andini, Roberto, Andrejak, Claire, Angheben, Andrea, Angoulvant, François, Ansart, Séverine, Anthonidass, Sivanesen, Antonelli, Massimo, de Brito, Carlos Alexandre Antunes, Anwar, Kazi Rubayet, Apriyana, Ardiyan, Arabi, Yaseen, Aragao, Irene, Arancibia, Francisco, Araujo, Carolline, Arcadipane, Antonio, Archambault, Patrick, Arenz, Lukas, Arlet, Jean-Benoît, Arnold-Day, Christel, Aroca, Ana, Arora, Lovkesh, Arora, Rakesh, Artaud-Macari, Elise, Aryal, Diptesh, Asaki, Motohiro, Asensio, Angel, Ashley, Elizabeth, Ashraf, Muhammad, Asif, Namra, Asim, Mohammad, Assie, Jean Baptiste, Asyraf, Amirul, Atique, Anika, Attanyake, A. M. Udara Lakshan, Auchabie, Johann, Aumaitre, Hugues, Auvet, Adrien, Axelsen, Eyvind W., Azemar, Laurène, Azoulay, Cecile, Bach, Benjamin, Bachelet, Delphine, Badr, Claudine, Bævre-Jensen, Roar, Baig, Nadia, Baillie, J. Kenneth, Baird, J Kevin, Bak, Erica, Bakakos, Agamemnon, Bakar, Nazreen Abu, Bal, Andriy, Balakrishnan, Mohanaprasanth, Balan, Valeria, Bani-Sadr, Firouzé, Barbalho, Renata, Barbosa, Nicholas Yuri, Barclay, Wendy S., Barnett, Saef Umar, Barnikel, Michaela, Barrasa, Helena, Barrelet, Audrey, Barrigoto, Cleide, Bartoli, Marie, Bartone, Cheryl, Baruch, Joaquín, Bashir, Mustehan, Basmaci, Romain, Basri, Muhammad Fadhli Hassin, Battaglini, Denise, Bauer, Jules, Rincon, Diego Fernando Bautista, Dow, Denisse Bazan, Beane, Abigail, Bedossa, Alexandra, Bee, Ker Hong, Begum, Husna, Behilill, Sylvie, Beiruti, Karine, Beishuizen, Albertus, Beljantsev, Aleksandr, Bellemare, David, Beltrame, Anna, Beltrão, Beatriz Amorim, Beluze, Marine, Benech, Nicolas, Benjiman, Lionel Eric, Benkerrou, Dehbia, Bennett, Suzanne, Bento, Luís, Berdal, Jan-Erik, Bergeaud, Delphine, Bergin, Hazel, Sobrino, José Luis Bernal, Bertoli, Giulia, Bertolino, Lorenzo, Bessis, Simon, Betz, Adam, Bevilcaqua, Sybille, Bezulier, Karine, Bhatt, Amar, Bhavsar, Krishna, Bianchi, Isabella, Bianco, Claudia, Bidin, Farah Nadiah, Singh, Moirangthem Bikram, Bin Humaid, Felwa, Bin Kamarudin, Mohd Nazlin, Bissuel, François, Biston, Patrick, Bitker, Laurent, Bitton, Jonathan, Blanco-Schweizer, Pablo, Blier, Catherine, Bloos, Frank, Blot, Mathieu, Blumberg, Lucille, Boccia, Filomena, Bodenes, Laetitia, Bogaarts, Alice, Bogaert, Debby, Boivin, Anne-Hélène, Bolze, Pierre-Adrien, Bompart, François, Bonelli, Patrizia, Bonfasius, Aurelius, Borges, Diogo, Borie, Raphaël, Bosse, Hans Martin, Botelho-Nevers, Elisabeth, Bouadma, Lila, Bouchaud, Olivier, Bouchez, Sabelline, Bouhmani, Dounia, Bouhour, Damien, Bouiller, Kévin, Bouillet, Laurence, Bouisse, Camile, Bounphiengsy, Thipsavanh, Bountthasavong, Latsaniphone, Boureau, Anne-Sophie, Bourke, John, Bouscambert, Maude, Bousquet, Aurore, Bouziotis, Jason, Boxma, Bianca, Boyer-Besseyre, Marielle, Boylan, Maria, Bozza, Fernando Augusto, Braconnier, Axelle, Braga, Cynthia, Brandenburger, Timo, Monteiro, Filipa Brás, Brazzi, Luca, Breen, Dorothy, Breen, Patrick, Brickell, Kathy, Browne, Alex, Browne, Shaunagh, Brozzi, Nicolas, Brunvoll, Sonja Hjellegjerde, Brusse-Keizer, Marjolein, Buchtele, Nina, Buesaquillo, Christian, Bugaeva, Polina, Buisson, Marielle, Buonsenso, Danilo, Burhan, Erlina, Burrell, Aidan, Bustos, Ingrid G., Butnaru, Denis, Cabie, André, Cabral, Susana, Caceres, Eder, Cadoz, Cyril, Callahan, Mia, Calligy, Kate, Calvache, Jose Andres, Caminiti, Caterina, Camões, João, Campana, Valentine, Campbell, Paul, Campisi, Josie, Canepa, Cecilia, Cantero, Mireia, Caraux-Paz, Pauline, Cárcel, Sheila, Cardellino, Chiara Simona, Cardoso, Filipa, Cardoso, Filipe, Cardoso, Nelson, Cardoso, Sofia, Carelli, Simone, Carlacci, Francesca, Carlier, Nicolas, Carmoi, Thierry, Carney, Gayle, Carqueja, Inês, Carret, Marie-Christine, Carrier, François Martin, Carroll, Ida, Carson, Gail, Carvalho, Leonor, Casanova, Maire-Laure, Cascão, Mariana, Casey, Siobhan, Casimiro, José, Cassandra, Bailey, Castañeda, Silvia, Castanheira, Nidyanara, Castor-Alexandre, Guylaine, Castrillón, Henry, Castro, Ivo, Catarino, Ana, Catherine, François-Xavier, Cattaneo, Paolo, Cavalin, Roberta, Cavalli, Giulio Giovanni, Cavayas, Alexandros, Ceccato, Adrian, Cervantes-Gonzalez, Minerva, Chair, Anissa, Chakveatze, Catherine, Chan, Adrienne, Chand, Meera, Auger, Christelle Chantalat, Chapplain, Jean-Marc, Chas, Julie, Chatterjee, Allegra, Chaudry, Mobin, Iñiguez, Jonathan Samuel Chávez, Chen, Anjellica, Chen, Yih-Sharng, Cheng, Matthew Pellan, Cheret, Antoine, Chetta, Alfredo Antonio, Chiarabini, Thibault, Chica, Julian, Chidambaram, Suresh Kumar, Tho, Leong Chin, Chirouze, Catherine, Chiumello, Davide, Cho, Hwa Jin, Cho, Sung-Min, Cholley, Bernard, Chommanam, Danoy, Chopin, Marie-Charlotte, Chow, Ting Soo, Chow, Yock Ping, Christy, Nathaniel, Chua, Hiu Jian, Chua, Jonathan, Cidade, Jose Pedro, Herreros, José Miguel Cisneros, Citarella, Barbara Wanjiru, Ciullo, Anna, Clarke, Emma, Clarke, Jennifer, Granado, Rolando Claure-Del, Clohisey, Sara, Cobb, Perren J., Codan, Cassidy, Cody, Caitriona, Coelho, Alexandra, Coles, Megan, Colin, Gwenhaël, Collins, Michael, Colombo, Sebastiano Maria, Combs, Pamela, Connor, Marie, Conrad, Anne, Contreras, Sofía, Conway, Elaine, Cooke, Graham S., Copland, Mary, Cordel, Hugues, Corley, Amanda, Cornelis, Sabine, Cornet, Alexander Daniel, Corpuz, Arianne Joy, Cortegiani, Andrea, Corvaisier, Grégory, Costigan, Emma, Couffignal, Camille, Couffin-Cadiergues, Sandrine, Courtois, Roxane, Cousse, Stéphanie, Cregan, Rachel, D’Orleans, Charles Crepy, Croonen, Sabine, Crowl, Gloria, Crump, Jonathan, Cruz, Claudina, Berm, Juan Luis Cruz, Rojo, Jaime Cruz, Csete, Marc, Cucino, Alberto, Cullen, Ailbhe, Cummings, Matthew, Curley, Ger, Curley, Gerard, Curlier, Elodie, Curran, Colleen, Custodio, Paula, D’Amico, Federico, D’Aragon, Frédérick, D’Ortenzio, Eric, da Silva Filipe, Ana, Da Silveira, Charlene, Dabaliz, Al-Awwab, Dagens, Andrew, Dahl, John Arne, Dahly, Darren, Dalton, Heidi, Dalton, Jo, Daly, Seamus, Daneman, Nick, Daniel, Corinne, Dankwa, Emmanuelle A, Dantas, Jorge, de Boer, Mark, de Loughry, Gillian, de Mendoza, Diego, De Montmollin, Etienne, de Oliveira França, Rafael Freitas, Oliveira, Ana Isabel de Pinho, De Rosa, Rosanna, De Rose, Cristina, de Silva, Thushan, de Vries, Peter, Deacon, Jillian, Dean, David, Debard, Alexa, DeBenedictis, Bianca, Debray, Marie-Pierre, DeCastro, Nathalie, Dechert, William, Deconninck, Lauren, Decours, Romain, Defous, Eve, Delacroix, Isabelle, Delaveuve, Eric, Delavigne, Karen, Delfos, Nathalie M., Deligiannis, Ionna, Dell’Amore, Andrea, Delmas, Christelle, Delobel, Pierre, Delsing, Corine, Demonchy, Elisa, Denis, Emmanuelle, Deplanque, Dominique, Depuydt, Pieter, Desai, Mehul, Descamps, Diane, Desvallées, Mathilde, Dewayanti, Santi, Dhanger, Pathik, Diallo, Alpha, Diamantis, Sylvain, Dias, André, Dias, Andrea, Diaz, Juan Jose, Diaz, Priscila, Diaz, Rodrigo, Didier, Kévin, Diehl, Jean-Luc, Dieperink, Wim, Dimet, Jérôme, Dinot, Vincent, Diop, Fara, Diouf, Alphonsine, Dishon, Yael, Djossou, Félix, Docherty, Annemarie B., Doherty, Helen, Dondorp, Arjen M, Dong, Andy, Donnelly, Christl A., Donnelly, Maria, Donohue, Chloe, Donohue, Sean, Donohue, Yoann, Doran, Peter, Dorival, Céline, Douangdala, Phouvieng, Douglas, James Joshua, Douma, Renee, Dournon, Nathalie, Downer, Triona, Downey, Joanne, Downing, Mark, Drake, Tom, Driscoll, Aoife, Dror, Amiel A., Dryden, Murray, Fonseca, Claudio Duarte, Dubee, Vincent, Dubos, François, Dubot-Pérès, Audrey, Ducancelle, Alexandre, Duculan, Toni, Dudman, Susanne, Duggal, Abhijit, Dunand, Paul, Dunning, Jake, Duplaix, Mathilde, Durante-Mangoni, Emanuele, Durham III, Lucian, Dussol, Bertrand, Duthoit, Juliette, Duval, Xavier, Dyrhol-Riise, Anne Margarita, Ean, Sim Choon, Echeverria-Villalobos, Marco, Economopoulos, Giorgio, Edelstein, Michael, Egan, Siobhan, Eggesbø, Linn Margrete, Eira, Carla, El Sanharawi, Mohammed, Elapavaluru, Subbarao, Elharrar, Brigitte, Ellerbroek, Jacobien, Ellingjord-Dale, Merete, Eloy, Philippine, Elshazly, Tarek, Elyazar, Iqbal, Enderle, Isabelle, Endo, Tomoyuki, Eng, Chan Chee, Engelmann, Ilka, Enouf, Vincent, Epaulard, Olivier, Escher, Martina, Esperatti, Mariano, Esperou, Hélène, Esposito-Farese, Marina, Estevão, João, Etienne, Manuel, Ettalhaoui, Nadia, Everding, Anna Greti, Evers, Mirjam, Fabre, Isabelle, Fabre, Marc, Faheem, Amna, Fahy, Arabella, Fairfield, Cameron J., Fakar, Zul, Fareed, Komal, Faria, Pedro, Farooq, Ahmed, Fateena, Hanan, Fatoni, Arie Zainul, Faure, Karine, Favory, Raphaël, Fayed, Mohamed, Feely, Niamh, Feeney, Laura, Fernandes, Jorge, Fernandes, Marília Andreia, Fernandes, Susana, Ferrand, François-Xavier, Devouge, Eglantine Ferrand, Ferrão, Joana, Ferrari, Carlo, Ferraz, Mário, Ferreira, Benigno, Ferreira, Isabel, Ferreira, Sílvia, Ferrer-Roca, Ricard, Ferriere, Nicolas, Ficko, Céline, Figueiredo-Mello, Claudia, Finlayson, William, Fiorda, Juan, Flament, Thomas, Flateau, Clara, Fletcher, Tom, Florio, Letizia Lucia, Flynn, Brigid, Flynn, Deirdre, Fogliazza, Federica, Foley, Claire, Foley, Jean, Fomin, Victor, Fonseca, Tatiana, Fontela, Patricia, Forsyth, Simon, Foster, Denise, Foti, Giuseppe, Fourn, Erwan, Fowler, Robert A., Fraher, Marianne, Franch-Llasat, Diego, Fraser, Christophe, Fraser, John F, Freire, Marcela Vieira, Ribeiro, Ana Freitas, French, Craig, Friedrich, Caren, Fritz, Ricardo, Fry, Stéphanie, Fuentes, Nora, Fukuda, Masahiro, Argin, G, Gaborieau, Valérie, Gaci, Rostane, Gagliardi, Massimo, Gagnard, Jean-Charles, Gagné, Nathalie, Gagneux-Brunon, Amandine, Gaião, Sérgio, Skeie, Linda Gail, Gallagher, Phil, Curto, Elena Gallego, Gamble, Carrol, Gani, Yasmin, Garan, Arthur, Garcia, Rebekha, Barrio, Noelia García, Garcia-Diaz, Julia, Garcia-Gallo, Esteban, Garimella, Navya, Garofalo, Federica, Garot, Denis, Garrait, Valérie, Gauli, Basanta, Gault, Nathalie, Gavin, Aisling, Gavrylov, Anatoliy, Gaymard, Alexandre, Gebauer, Johannes, Geraud, Eva, Morlaes, Louis Gerbaud, Germano, Nuno, Ghisulal, Praveen Kumar, Ghosn, Jade, Giani, Marco, Giaquinto, Carlo, Gibson, Jess, Gigante, Tristan, Gilg, Morgane, Gilroy, Elaine, Giordano, Guillermo, Girvan, Michelle, Gissot, Valérie, Gitaka, Jesse, Giwangkancana, Gezy, Glikman, Daniel, Glybochko, Petr, Gnall, Eric, Goco, Geraldine, Goehringer, François, Goepel, Siri, Goffard, Jean-Christophe, Goh, Jin Yi, Golob, Jonathan, Gomes, Rui, Gomez, Kyle, Gómez-Junyent, Joan, Gominet, Marie, Gonçalves, Bronner P., Gonzalez, Alicia, Gordon, Patricia, Gorelik, Yanay, Gorenne, Isabelle, Goubert, Laure, Goujard, Cécile, Goulenok, Tiphaine, Grable, Margarite, Graf, Jeronimo, Grandin, Edward Wilson, Granier, Pascal, Grasselli, Giacomo, Grazioli, Lorenzo, Green, Christopher A., Greene, Courtney, Greenhalf, William, Greffe, Segolène, Grieco, Domenico Luca, Griffee, Matthew, Griffiths, Fiona, Grigoras, Ioana, Groenendijk, Albert, Lordemann, Anja Grosse, Gruner, Heidi, Gu, Yusing, Guarracino, Fabio, Guedj, Jérémie, Guego, Martin, Guellec, Dewi, Guerguerian, Anne-Marie, Guerreiro, Daniela, Guery, Romain, Guillaumot, Anne, Guilleminault, Laurent, de Castro, Maisa Guimarães, Guimard, Thomas, Haalboom, Marieke, Haber, Daniel, Habraken, Hannah, Hachemi, Ali, Hackmann, Amy, Hadri, Nadir, Haidri, Fakhir, Hakak, Sheeba, Hall, Adam, Hall, Matthew, Halpin, Sophie, Hameed, Jawad, Hamer, Ansley, Hamers, Raph L., Hamidfar, Rebecca, Hammarström, Bato, Hammond, Terese, Han, Lim Yuen, Haniffa, Rashan, Hao, Kok Wei, Hardwick, Hayley, Harrison, Ewen M., Harrison, Janet, Harrison, Samuel Bernard Ekow, Hartman, Alan, Hasan, Mohd Shahnaz, Hashmi, Junaid, Hashmi, Madiha, Hayes, Ailbhe, Hays, Leanne, Heerman, Jan, Heggelund, Lars, Hendry, Ross, Hennessy, Martina, Henriquez-Trujillo, Aquiles, Hentzien, Maxime, Hernandez-Montfort, Jaime, Herr, Daniel, Hershey, Andrew, Hesstvedt, Liv, Hidayah, Astarini, Higgins, Dawn, Higgins, Eibhilin, Hinchion, Rita, Hinton, Samuel, Hiraiwa, Hiroaki, Hirkani, Haider, Hitoto, Hikombo, Ho, Antonia, Ho, Yi Bin, Hoctin, Alexandre, Hoffmann, Isabelle, Hoh, Wei Han, Hoiting, Oscar, Holt, Rebecca, Holter, Jan Cato, Horby, Peter, Horcajada, Juan Pablo, Hoshino, Koji, Hoshino, Kota, Houas, Ikram, Hough, Catherine L., Houltham, Stuart, Hsu, Jimmy Ming-Yang, Hulot, Jean-Sébastien, Huo, Stella, Hussain, Iqbal, Ijaz, Samreen, Illes, Hajnal-Gabriela, Imbert, Patrick, Imran, Mohammad, Sikander, Rana Imran, Imtiaz, Aftab, Inácio, Hugo, Dominguez, Carmen Infante, Ing, Yun Sii, Iosifidis, Elias, Ippolito, Mariachiara, Isgett, Sarah, Isidoro, Tiago, Ismail, Nadiah, Isnard, Margaux, Istre, Mette Stausland, Itai, Junji, Ito, Asami, Ivulich, Daniel, Jaafar, Danielle, Jaafoura, Salma, Jabot, Julien, Jackson, Clare, Jamieson, Nina, Jaquet, Pierre, Jassat, Waasila, Jaud-Fischer, Coline, Jaureguiberry, Stéphane, Javidfar, Jeffrey, Jaworsky, Denise, Jego, Florence, Jelani, Anilawati Mat, Jenum, Synne, Jimbo-Sotomayor, Ruth, Joe, Ong Yiaw, García, Ruth N. Jorge, Jørgensen, Silje Bakken, Joseph, Cédric, Joseph, Mark, Joshi, Swosti, Jourdain, Mercé, Jouvet, Philippe, June, Jennifer, Jung, Anna, Jung, Hanna, Juzar, Dafsah, Kafif, Ouifiya, Kaguelidou, Florentia, Kaisbain, Neerusha, Kaleesvran, Thavamany, Kali, Sabina, Kalicinska, Alina, Kalleberg, Karl Trygve, Kalomoiri, Smaragdi, Kamaluddin, Muhammad Aisar Ayadi, Kamaruddin, Zul Amali Che, Kamarudin, Nadiah, Kamineni, Kavita, Kandamby, Darshana Hewa, Kandel, Chris, Kang, Kong Yeow, Kanwal, Darakhshan, Kanyawati, Dyah, Karpayah, Pratap, Karsies, Todd, Kartsonaki, Christiana, Kasugai, Daisuke, Kataria, Anant, Katz, Kevin, Kaur, Aasmine, Kawasaki, Tatsuya, Kay, Christy, Keane, Hannah, Keating, Seán, Kedia, Pulak, Kelly, Andrea, Kelly, Aoife, Kelly, Claire, Kelly, Niamh, Kelly, Sadie, Kelly, Yvelynne, Kelsey, Maeve, Kennedy, Ryan, Kennon, Kalynn, Keomany, Sommay, Kernan, Maeve, Kerroumi, Younes, Keshav, Sharma, Kestelyn, Evelyne, Khalid, Imrana, Khalid, Osama, Khalil, Antoine, Khan, Coralie, Khan, Irfan, Khan, Quratul Ain, Khanal, Sushil, Khatak, Abid, Khawaja, Amin, Kherajani, Krish, Kho, Michelle E., Khoo, Denisa, Khoo, Ryan, Khoo, Saye, Khoso, Nasir, Kiat, Khor How, Kida, Yuri, Kihuga, Harrison, Kiiza, Peter, Granerud, Beathe Kiland, Kildal, Anders Benjamin, Kim, Jae Burm, Kimmoun, Antoine, Kindgen-Milles, Detlef, King, Alexander, Kitamura, Nobuya, Kjetland, Eyrun Floerecke Kjetland, Klenerman, Paul, Klont, Rob, Bekken, Gry Kloumann, Knight, Stephen R, Kobbe, Robin, Kodippily, Chamira, Vasconcelos, Malte Kohns, Koirala, Sabin, Komatsu, Mamoru, Korten, Volkan, Kosgei, Caroline, Kpangon, Arsène, Krawczyk, Karolina, Krishnan, Sudhir, Krishnan, Vinothini, Kruglova, Oksana, Kumar, Deepali, Kumar, Ganesh, Kumar, Mukesh, Vecham, Pavan Kumar, Kuriakose, Dinesh, Kurtzman, Ethan, Kusumastuti, Neurinda Permata, Kutsogiannis, Demetrios, Kutsyna, Galyna, Kyriakoulis, Konstantinos, L’Her, Erwan, Lachatre, Marie, Lacoste, Marie, Laffey, John G., Lagrange, Marie, Laine, Fabrice, Lairez, Olivier, Lakhey, Sanjay, Lalueza, Antonio, Lambert, Marc, Lamontagne, François, Langelot-Richard, Marie, Langlois, Vincent, Lantang, Eka Yudha, Lanza, Marina, Laouénan, Cédric, Laribi, Samira, Lariviere, Delphine, Lasry, Stéphane, Lath, Sakshi, Latif, Naveed, Launay, Odile, Laureillard, Didier, Lavie-Badie, Yoan, Law, Andrew, Law, Andy, Lawrence, Cassie, Lawrence, Teresa, Le, Minh, Le Bihan, Clément, Le Bris, Cyril, Le Falher, Georges, Le Fevre, Lucie, Le Hingrat, Quentin, Le Maréchal, Marion, Le Mestre, Soizic, Le Moal, Gwenaël, Le Moing, Vincent, Le Nagard, Hervé, Le Turnier, Paul, Leal, Ema, Santos, Marta Leal, Lee, Biing Horng, Lee, Heng Gee, Lee, James, Lee, Su Hwan, Lee, Todd C., Lee, Yi Lin, Leeming, Gary, Lefebvre, Bénédicte, Lefebvre, Laurent, Lefevre, Benjamin, LeGac, Sylvie, Lelievre, Jean-Daniel, Lellouche, François, Lemaignen, Adrien, Lemee, Véronique, Lemeur, Anthony, Lemmink, Gretchen, Lene, Ha Sha, Lennon, Jenny, León, Rafael, Leone, Marc, Leone, Michela, Lepiller, Quentin, Lescure, François-Xavier, Lesens, Olivier, Lesouhaitier, Mathieu, Lester-Grant, Amy, Letizia, Andrew, Levy, Bruno, Levy, Yves, Levy-Marchal, Claire, Lewandowska, Katarzyna, Bassi, Gianluigi Li, Liang, Janet, Liaquat, Ali, Liegeon, Geoffrey, Lim, Kah Chuan, Lim, Wei Shen, Lima, Chantre, Lina, Bruno, Lina, Lim, Lind, Andreas, Lingad, Maja Katherine, Lingas, Guillaume, Lion-Daolio, Sylvie, Lissauer, Samantha, Liu, Keibun, Livrozet, Marine, Lizotte, Patricia, Loforte, Antonio, Lolong, Navy, Loon, Leong Chee, Lopes, Diogo, Lopez-Colon, Dalia, Loschner, Anthony L., Loubet, Paul, Loufti, Bouchra, Louis, Guillame, Lourenco, Silvia, Lovelace-Macon, Lara, Low, Lee Lee, Lowik, Marije, Loy, Jia Shyi, Lucet, Jean Christophe, Bermejo, Carlos Lumbreras, Luna, Carlos M., Lungu, Olguta, Luong, Liem, Luque, Nestor, Luton, Dominique, Lwin, Nilar, Lyons, Ruth, Maasikas, Olavi, Mabiala, Oryane, MacDonald, Sarah, Machado, Moïse, Macheda, Gabriel, Sanchez, Juan Macias, Madhok, Jai, Madiha, Hashmi, de la Calle, Guillermo Maestro, Magara, Jacob, Maglietta, Giuseppe, Mahieu, Rafael, Mahy, Sophie, Maia, Ana Raquel, Maier, Lars S., Maillet, Mylène, Maitre, Thomas, Majori, Maria, Malfertheiner, Maximilian, Malik, Nadia, Mallon, Paddy, Maltez, Fernando, Malvy, Denis, Mammi, Patrizia, Manda, Victoria, Mandei, Jose M., Mandelbrot, Laurent, Manetta, Frank, Mankikian, Julie, Manning, Edmund, Manuel, Aldric, Malaque, Ceila Maria Sant’Ana, Marino, Daniel, Marino, Flávio, Markowicz, Samuel, Eid, Charbel Maroun, Marques, Ana, Marquis, Catherine, Marsh, Brian, Marsh, Laura, Marshal, Megan, Marshall, John, Martelli, Celina Turchi, Martin, Dori-Ann, Martin, Emily, Martin-Blondel, Guillaume, Martin-Loeches, Ignacio, Martin-Quiros, Alejandro, Martinelli, Alessandra, Martinot, Martin, Martins, Ana, Martins, João, Martins, Nuno, Rego, Caroline Martins, Martucci, Gennaro, Martynenko, Olga, Marwali, Eva Miranda, Marzukie, Marsilla, Jimenez, Juan Fernado Masa, Maslove, David, Mason, Phillip, Mason, Sabina, Masood, Sobia, Nor, Basri Mat, Matan, Moshe, Fernandes, Henrique Mateus, Mathew, Meghena, Mathieu, Daniel, Mattei, Mathieu, Matulevics, Romans, Maulin, Laurence, Maxwell, Michael, Maynar, Javier, Mayxay, Mayfong, Mazzoni, Thierry, Mc Evoy, Natalie, Mc Sweeney, Lisa, McArthur, Colin, McCarthy, Aine, McCarthy, Anne, McCloskey, Colin, McConnochie, Rachael, McDermott, Sherry, McDonald, Sarah E., McElroy, Aine, McElwee, Samuel, McEneany, Victoria, McGeer, Allison, McKay, Chris, McKeown, Johnny, McLean, Kenneth A., McNally, Paul, McNicholas, Bairbre, McPartlan, Elaine, Meaney, Edel, Mear-Passard, Cécile, Mechlin, Maggie, Meher, Maqsood, Mehkri, Omar, Mele, Ferruccio, Melo, Luis, Memon, Kashif, Mendes, Joao, Menkiti, Ogechukwu, Menon, Kusum, Mentré, France, Mentzer, Alexander J., Mercier, Emmanuelle, Mercier, Noémie, Merckx, Antoine, Mergeay-Fabre, Mayka, Mergler, Blake, Merson, Laura, Meschi, Tiziana, Mesquita, António, Meta, Roberta, Metwally, Osama, Meybeck, Agnès, Meyer, Dan, Meynert, Alison M., Meysonnier, Vanina, Meziane, Amina, Mezidi, Mehdi, Michelagnoli, Giuliano, Michelanglei, Céline, Michelet, Isabelle, Mihelis, Efstathia, Mihnovit, Vladislav, Miranda-Maldonado, Hugo, Misnan, Nor Arisah, Mohamed, Nik Nur Eliza, Mohamed, Tahira Jamal, Moin, Asma, Molina, David, Molinos, Elena, Molloy, Brenda, Mone, Mary, Monteiro, Agostinho, Montes, Claudia, Montrucchio, Giorgia, Moore, Sarah, Moore, Shona C., Cely, Lina Morales, Moro, Lucia, Tutillo, Diego Rolando Morocho, Morton, Ben, Motherway, Catherine, Motos, Ana, Mouquet, Hugo, Perrot, Clara Mouton, Moyet, Julien, Mudara, Caroline, Mufti, Aisha Kalsoom, Muh, Ng Yong, Muhamad, Dzawani, Mullaert, Jimmy, Müller, Fredrik, Müller, Karl Erik, Munblit, Daniel, Muneeb, Syed, Munir, Nadeem, Munshi, Laveena, Murphy, Aisling, Murphy, Lorna, Murris, Marlène, Murthy, Srinivas, Musaab, Himed, Mutti, Carlotta, Muvindi, Himasha, Muyandy, Gugapriyaa, Myrodia, Dimitra Melia, Mohd-Hanafiah, Farah Nadia, Nagpal, Dave, 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Eoin, Wham, Murray, Whelan, Bryan, White, Nicole, Wicky, Paul Henri, Wiedemann, Aurélie, Wijaya, Surya Otto, Wille, Keith, Willems, Suzette, Williams, Virginie, Wils, Evert-Jan, Wong, Calvin, Wong, Teck Fung, Wong, Xin Ci, Wong, Yew Sing, Wright, Natalie, Xian, Gan Ee, Xian, Lim Saio, Xuan, Kuan Pei, Xynogalas, Ioannis, Yacoub, Sophie, Yakop, Siti Rohani Binti Mohd, Yamazaki, Masaki, Yazdanpanah, Yazdan, Hing, Nicholas Yee Liang, Yelnik, Cécile, Yeoh, Chian Hui, Yerkovich, Stephanie, Yiaye, Touxiong, Yokoyama, Toshiki, Yonis, Hodane, Yousif, Obada, Yuliarto, Saptadi, Zaaqoq, Akram, Zabbe, Marion, Zacharowski, Kai, Zahid, Masliza, Zahran, Maram, Zaidan, Nor Zaila Binti, Zambon, Maria, Zambrano, Miguel, Zanella, Alberto, Zawadka, Konrad, Zaynah, Nurul, Zayyad, Hiba, Zoufaly, Alexander, Zucman, David, Fryer, Daniel Vidali, Duque, Sara, Fuentes, Yuli V., Baruch, Joaquin, Beane, Abi, Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pontchaillou [Rennes], ARN régulateurs bactériens et médecine (BRM), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre National de Référence des virus des infections respiratoires (dont la grippe) - National Reference Center Virus Influenzae [Paris] (CNR - laboratoire coordonnateur), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), University of La Sabana = Universitad de la Sabana, University of Queensland [Brisbane], University of British Columbia (UBC), University of Oxford, The investigators acknowledge: This work is part of the Grand Challenges ICODA pilot initiative, delivered by Health Data Research UK and funded by the Bill & Melinda Gates Foundation and the Minderoo Foundation. The philanthropic support of the donors to the University of Oxford’s COVID-19 Research Response Fund, UK Foreign, Commonwealth and Development Office and Wellcome [215091/Z/18/Z and 220757/Z/20/Z], the Bill & Melinda Gates Foundation [OPP1209135], the National Institute for Health Research (NIHR, award CO-CIN-01), the Medical Research Council (MRC, grant MC_PC_19059), the NIHR Health Protection Research Unit (HPRU) in Emerging and Zoonotic Infections at University of Liverpool in partnership with Public Health England (PHE)(award 200907), NIHR HPRU in Respiratory Infections at Imperial College London with PHE (award 200927), Liverpool Experimental Cancer Medicine Centre (grant C18616/A25153), NIHR Biomedical Research Centre at Imperial College London (award IS-BRC-1215-20013), NIHR Clinical Research Network (infrastructure support), CIHR Coronavirus Rapid Research Funding Opportunity OV2170359 and was coordinated out of Sunnybrook Research Institute, the endorsement of the Irish Critical Care- Clinical Trials Group, co-ordinated in Ireland by the Irish Critical Care- Clinical Trials Network at University College Dublin and funded by the Health Research Board of Ireland [CTN-2014-12], Rapid European COVID-19 Emergency Response research (RECOVER) [H2020 project 101003589], European Clinical Research Alliance on Infectious Diseases (ECRAID) [965313], COVID clinical management team, AIIMS, Rishikesh, India, Cambridge NIHR Biomedical Research Centre, the dedication and hard work of the Groote Schuur Hospital Covid ICU Team, the Groote Schuur nursing and University of Cape Town registrar bodies coordinated by the Division of Critical Care at the University of Cape Town, Wellcome Trust fellowship [205228/Z/16/Z], the Liverpool School of Tropical Medicine, the University of Oxford, the dedication and hard work of the Norwegian SARS-CoV-2 study team, the Research Council of Norway grant no 312780, a philanthropic donation from Vivaldi Invest A/S owned by Jon Stephenson von Tetzchner, Innovative Medicines Initiative Joint Undertaking under Grant Agreement No. 115523 COMBACTE, resources of which are composed of financial contribution from the European Union’s Seventh Framework Programme (FP7/2007–2013) and EFPIA companies, in-kind contribution, preparedness work conducted by the Short Period Incidence Study of Severe Acute Respiratory Infection, Stiftungsfonds zur Förderung der Bekämpfung der Tuberkulose und anderer Lungenkrankheiten of the City of Vienna, Project Number: APCOV22BGM, Italian Ministry of Health 'Fondi Ricerca corrente–L1P6' to IRCCS Ospedale Sacro Cuore–Don Calabria, Australian Department of Health grant (3273191), Gender Equity Strategic Fund at University of Queensland, Artificial Intelligence for Pandemics (A14PAN) at University of Queensland, the Australian Research Council Centre of Excellence for Engineered Quantum Systems (EQUS, CE170100009), the Prince Charles Hospital Foundation, Australia, UK Medical Research Council Clinical Research Training Fellowship MR/V001671/1, Instituto de Salud Carlos III, Ministerio de Ciencia, Spain, Brazil, National Council for Scientific and Technological Development Scholarship number 303953/2018-7, Firland Foundation, Shoreline, Washington, USA, the French COVID cohort (NCT04262921) is sponsored by INSERM and is funding by the REACTing (REsearch & ACtion emergING infectious diseases) consortium and by a grant of the French Ministry of Health (PHRC n°20-0424). This work uses Data/Material provided by patients and collected by the NHS as part of their care and support #DataSavesLives. The Data/materials used for this research were obtained from ISARIC4C. ISARIC4C Investigators collated the COVID-19 Clinical Information Network (CO-CIN) data., European Project: 101003589, H2020-SC1-PHE-CORONAVIRUS-2020,RECOVER(2020), Bill & Melinda Gates Foundation, Minderoo Foundation, Commonwealth Foundation, Wellcome Trust, National Institute for Health Research (UK), Medical Research Council (UK), University of Liverpool, Imperial College London, Canadian Institutes of Health Research, Sunnybrook Research Institute, Health Research Board (Ireland), European Commission, All India Institute of Medical Science, University of Cape Town, Research Council of Norway, Innovative Medicines Initiative, Governo Italiano, University of Queensland, Australian Research Council, Prince Charles Hospital Foundation, Instituto de Salud Carlos III, Institut National de la Santé et de la Recherche Médicale (France), Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil), Garcia-Gallo, Esteban, Merson, Laura, Kennon, Kalynn, Kelly, Sadie, Citarella, Barbara Wanjiru, Fryer, Daniel Vidali, Shrapnel, Sally, Lee, Jame, Duque, Sara, Fuentes, Yuli V, Balan, Valeria, Smith, Sue, Wei, Jia, Gonçalves, Bronner P, Russell, Clark D, Sigfrid, Louise, Dagens, Andrew, Olliaro, Piero L, Baruch, Joaquin, Kartsonaki, Christiana, Dunning, Jake, Rojek, Amanda, Rashan, Aasiyah, Beane, Abi, Murthy, Sriniva, Reyes, Luis Felipe, ISARIC Clinical Characterization Group: Ali Abbas, Sheryl Ann Abdukahil, Nurul Najmee Abdulkadir, Ryuzo Abe, Laurent Abel, Lara Absil, Kamal Abu Jabal, Hiba Abu Zayyad, Subhash Acharya, Andrew Acker, Shingo Adachi, Elisabeth Adam, Enrico Adriano, Diana Adrião, Saleh Al Ageel, Shakeel Ahmed, Marina Aiello, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Eman Al Qasim, Tala Al-Dabbous, Abdulrahman Al-Fares, Razi Alalqam, Angela Alberti, Senthilkumar Alegesan, Cynthia Alegre, Marta Alessi, Beatrice Alex, Kévin Alexandre, Huda Alfoudri, Adam Ali, Imran Ali, Naseem Ali Shah, Naseem Ali Sheikh, Kazali Enagnon Alidjnou, Jeffrey Aliudin, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Aneela Altaf, João Alves, João Melo Alves, Rita Alves, Maria Amaral, Nur Amira, Heidi Ammerlaan, Phoebe Ampaw, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Kazi Rubayet Anwar, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Ana Aroca, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Motohiro Asaki, Angel Asensio, Elizabeth Ashley, Muhammad Ashraf, Namra Asif, Mohammad Asim, Jean Baptiste Assie, Amirul Asyraf, Anika Atique, A M Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Eyvind W Axelsen, Laurène Azemar, Cecile Azoulay, Benjamin Bach, Delphine Bachelet, Claudine Badr, Roar Bævre-Jensen, Nadia Baig, J Kenneth Baillie, J Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Andriy Bal, Mohanaprasanth Balakrishnan, Valeria Balan, Firouzé Bani-Sadr, Renata Barbalho, Nicholas Yuri Barbosa, Wendy S Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Audrey Barrelet, Cleide Barrigoto, Marie Bartoli, Cheryl Bartone, Joaquín Baruch, Mustehan Bashir, Romain Basmaci, Muhammad Fadhli Hassin Basri, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Abigail Beane, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Sylvie Behilill, Karine Beiruti, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Dehbia Benkerrou, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Delphine Bergeaud, Hazel Bergin, José Luis Bernal Sobrino, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Adam Betz, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, 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Luis Periel, Thomas Perpoint, Antonio Pesenti, Vincent Pestre, Lenka Petrou, Ventzislava Petrov-Sanchez, Michele Petrovic, Frank Olav Pettersen, Gilles Peytavin, Scott Pharand, Ooyanong Phonemixay, Michael Piagnerelli, Walter Picard, Olivier Picone, Maria de Piero, Carola Pierobon, Djura Piersma, Carlos Pimentel, Raquel Pinto, Catarina Pires, Isabelle Pironneau, Lionel Piroth, Roberta Pisi, Ayodhia Pitaloka, Riinu Pius, Simone Piva, Laurent Plantier, Hon Shen Png, Julien Poissy, Ryadh Pokeerbux, Maria Pokorska-Spiewak, Sergio Poli, Georgios Pollakis, Diane Ponscarme, Jolanta Popielska, Diego Bastos Porto, Andra-Maris Post, Douwe F Postma, Pedro Povoa, Diana Póvoas, Jeff Powis, Sofia Prapa, Viladeth Praphasiri, Sébastien Preau, Christian Prebensen, Jean-Charles Preiser, Anton Prinssen, Mark G Pritchard, Gamage Dona Dilanthi Priyadarshani, Lucia Proença, Sravya Pudota, Oriane Puéchal, Bambang Pujo Semedi, Mathew Pulicken, Matteo Puntoni, Gregory Purcell, Luisa Quesada, Vilmaris Quinones-Cardona, Víctor Quirós González, Else Quist-Paulsen, Mohammed Quraishi, Maia Rabaa, Christian Rabaud, Ebenezer Rabindrarajan, Aldo Rafael, Marie Rafiq, Gabrielle Ragazzo, Mutia Rahardjani, Ahmad Kashfi Haji Ab Rahman, Rozanah Abd Rahman, Arsalan Rahutullah, Fernando Rainieri, Giri Shan Rajahram, Pratheema Ramachandran, Nagarajan Ramakrishnan, Kollengode Ramanathan, Ahmad Afiq Ramli, Blandine Rammaert, Grazielle Viana Ramos, Anais Rampello, Asim Rana, Rajavardhan Rangappa, Ritika Ranjan, Elena Ranza, Christophe Rapp, Aasiyah Rashan, Thalha Rashan, Ghulam Rasheed, Menaldi Rasmin, Indrek Rätsep, Cornelius Rau, Francesco Rausa, Tharmini Ravi, Ali Raza, Andre Real, Stanislas Rebaudet, Sarah Redl, Brenda Reeve, Attaur Rehman, Liadain Reid, Dag Henrik Reikvam, Renato Reis, Jordi Rello, Jonathan Remppis, Martine Remy, Hongru Ren, Hanna Renk, Anne-Sophie Resseguier, Matthieu Revest, Oleksa Rewa, Luis Felipe Reyes, Tiago Reyes, Maria Ines Ribeiro, Antonia Ricchiuto, David Richardson, Denise Richardson, Laurent Richier, Siti Nurul Atikah Ahmad Ridzuan, Jordi Riera, Ana L Rios, Asgar Rishu, Patrick Rispal, Karine Risso, Maria Angelica Rivera Nuñez, Nicholas Rizer, Chiara Robba, André Roberto, Stephanie Roberts, David L Robertson, Olivier Robineau, Ferran Roche-Campo, Paola Rodari, Simão Rodeia, Julia Rodriguez Abreu, Bernhard Roessler, Claire Roger, Pierre-Marie Roger, Emmanuel Roilides, Amanda Rojek, Juliette Romaru, Roberto Roncon-Albuquerque Jr, Mélanie Roriz, Manuel Rosa-Calatrava, Michael Rose, Dorothea Rosenberger, Nurul Hidayah Mohammad Roslan, Andrea Rossanese, Matteo Rossetti, Sandra Rossi, Bénédicte Rossignol, Patrick Rossignol, Stella Rousset, Carine Roy, Benoît Roze, Desy Rusmawatiningtyas, Clark D Russell, Maeve Ryan, Maria Ryan, Mazankowski Heart Institute Ryckaert, Steffi Ryckaert, Aleksander Rygh Holten, Isabela Saba, Luca Sacchelli, Sairah Sadaf, Musharaf Sadat, Valla Sahraei, Nadia Saidani, Maximilien Saint-Gilles, Pranya Sakiyalak, Nawal Salahuddin, Leonardo Salazar, Jodat Saleem, Nazal Saleh, Gabriele Sales, Stéphane Sallaberry, Charlotte Salmon Gandonniere, Hélène Salvator, Olivier Sanchez, Xavier Sánchez Choez, Kizy Sanchez de Oliveira, Angel Sanchez-Miralles, Vanessa Sancho-Shimizu, Gyan Sandhu, Zulfiqar Sandhu, Pierre-François Sandrine, Oana Sandulescu, Marlene Santos, Shirley Sarfo-Mensah, Bruno Sarmento Banheiro, Iam Claire E Sarmiento, Benjamine Sarton, Ankana Satya, Sree Satyapriya, Rumaisah Satyawati, Egle Saviciute, Parthena Savvidou, Yen Tsen Saw, Justin Schaffer, Tjard Schermer, Arnaud Scherpereel, Marion Schneider, Stephan Schroll, Michael Schwameis, Gary Schwartz, Janet T Scott, James Scott-Brown, Nicholas Sedillot, Tamara Seitz, Jaganathan Selvanayagam, Mageswari Selvarajoo, Caroline Semaille, Malcolm G Semple, Rasidah Bt Senian, Eric Senneville, Claudia Sepulveda, Filipa Sequeira, Tânia Sequeira, Ary Serpa Neto, Pablo Serrano Balazote, Ellen Shadowitz, Syamin Asyraf Shahidan, Mohammad Shamsah, Anuraj Shankar, Shaikh Sharjeel, Pratima Sharma, Catherine A Shaw, Victoria Shaw, Ashraf Sheharyar, Dr Rajesh Mohan Shetty, Rohan Shetty, Haixia Shi, Nisreen Shiban, Mohiuddin Shiekh, Takuya Shiga, Nobuaki Shime, Hiroaki Shimizu, Keiki Shimizu, Naoki Shimizu, Sally Shrapnel, Pramesh Sundar Shrestha, Shubha Kalyan Shrestha, Hoi Ping Shum, Nassima Si Mohammed, Ng Yong Siang, Jeanne Sibiude, Bountoy Sibounheuang, Atif Siddiqui, Louise Sigfrid, Piret Sillaots, Catarina Silva, Maria Joao Silva, Rogério Silva, Benedict Sim Lim Heng, Wai Ching Sin, Dario Sinatti, Budha Charan Singh, Punam Singh, Pompini Agustina Sitompul, Karisha Sivam, Vegard Skogen, Sue Smith, Benjamin Smood, Coilin Smyth, Michelle Smyth, Morgane Snacken, Dominic So, Tze Vee Soh, Lene Bergendal Solberg, Joshua Solomon, Tom Solomon, Emily Somers, Agnès Sommet, Myung Jin Song, Rima Song, Tae Song, Jack Song Chia, Michael Sonntagbauer, Azlan Mat Soom, Arne Søraas, Camilla Lund Søraas, Alberto Sotto, Edouard Soum, Ana Chora Sousa, Marta Sousa, Maria Sousa Uva, Vicente Souza-Dantas, Alexandra Sperry, Elisabetta Spinuzza, B P Sanka Ruwan Sri Darshana, Shiranee Sriskandan, Sarah Stabler, Thomas Staudinger, Stephanie-Susanne Stecher, Trude Steinsvik, Ymkje Stienstra, Birgitte Stiksrud, Eva Stolz, Amy Stone, Adrian Streinu-Cercel, Anca Streinu-Cercel, Samantha Strudwick, Ami Stuart, David Stuart, Decy Subekti, Gabriel Suen, Jacky Y Suen, Asfia Sultana, Charlotte Summers, Dubravka Supic, Deepashankari Suppiah, Magdalena Surovcová, Suwarti Suwarti, Andrey A Svistunov, Sarah Syahrin, Konstantinos Syrigos, Jaques Sztajnbok, Konstanty Szuldrzynski, Shirin Tabrizi, Fabio S Taccone, Lysa Tagherset, Shahdattul Mawarni Taib, Ewa Talarek, Sara Taleb, Jelmer Talsma, Renaud Tamisier, Maria Lawrensia Tampubolon, Kim Keat Tan, Le Van Tan, Yan Chyi Tan, Clarice Tanaka, Hiroyuki Tanaka, Taku Tanaka, Hayato Taniguchi, Huda Taqdees, Arshad Taqi, Coralie Tardivon, Pierre Tattevin, M Azhari Taufik, Hassan Tawfik, Richard S Tedder, Tze Yuan Tee, João Teixeira, Sofia Tejada, Marie-Capucine Tellier, Sze Kye Teoh, Vanessa Teotonio, François Téoulé, Pleun Terpstra, Olivier Terrier, Nicolas Terzi, Hubert Tessier-Grenier, Adrian Tey, Alif Adlan Mohd Thabit, Anand Thakur, Zhang Duan Tham, Suvintheran Thangavelu, Vincent Thibault, Simon-Djamel Thiberville, Benoît Thill, Jananee Thirumanickam, Shaun Thompson, David Thomson, Emma C Thomson, Surain Raaj Thanga Thurai, Duong Bich Thuy, Ryan S Thwaites, Andrea Ticinesi, Paul Tierney, Vadim Tieroshyn, Peter S Timashev, Jean-François Timsit, Bharath Kumar Tirupakuzhi Vijayaraghavan, Noémie Tissot, Jordan Zhien Yang Toh, Maria Toki, Kristian Tonby, Sia Loong Tonnii, Antoni Torres, Margarida Torres, Rosario Maria Torres Santos-Olmo, Hernando Torres-Zevallos, Michael Towers, Tony Trapani, Théo Treoux, Huynh Trung Trieu, Cécile Tromeur, Ioannis Trontzas, Tiffany Trouillon, Jeanne Truong, Christelle Tual, Sarah Tubiana, Helen Tuite, Jean-Marie Turmel, Lance C W Turtle, Anders Tveita, Pawel Twardowski, Makoto Uchiyama, P G Ishara Udayanga, Andrew Udy, Roman Ullrich, Alberto Uribe, Asad Usman, Timothy M Uyeki, Cristinava Vajdovics, Luís Val-Flores, Piero Valentini, Ana Luiza Valle, Amélie Valran, Ilaria Valzano, Stijn Van de Velde, Marcel van den Berge, Machteld Van der Feltz, Job van der Palen, Paul van der Valk, Nicky Van Der Vekens, Peter Van der Voort, Sylvie Van Der Werf, Marlice van Dyk, Laura van Gulik, Jarne Van Hattem, Carolien van Netten, Gitte Van Twillert, Ilonka van Veen, Noémie Vanel, Henk Vanoverschelde, Pooja Varghese, Michael Varrone, Shoban Raj Vasudayan, Charline Vauchy, Shaminee Veeran, Aurélie Veislinger, Sebastian Vencken, Sara Ventura, Annelies Verbon, James Vickers, José Ernesto Vidal, César Vieira, Deepak Vijayan, Joy Ann Villanueva, Judit Villar, Pierre-Marc Villeneuve, Andrea Villoldo, Nguyen Van Vinh Chau, Gayatri Vishwanathan, Benoit Visseaux, Hannah Visser, Chiara Vitiello, Manivanh Vongsouvath, Harald Vonkeman, Fanny Vuotto, Noor Hidayu Wahab, Suhaila Abdul Wahab, Nadirah Abdul Wahid, Marina Wainstein, Wan Fadzlina Wan Muhd Shukeri, Chih-Hsien Wang, Steve Webb, Jia Wei, Katharina Weil, Tan Pei Wen, Sanne Wesselius, T Eoin West, Murray Wham, Bryan Whelan, Nicole White, Paul Henri Wicky, Aurélie Wiedemann, Surya Otto Wijaya, Keith Wille, Suzette Willems, Virginie Williams, Evert-Jan Wils, Calvin Wong, Teck Fung Wong, Xin Ci Wong, Yew Sing Wong, Natalie Wright, Gan Ee Xian, Lim Saio Xian, Kuan Pei Xuan, Ioannis Xynogalas, Sophie Yacoub, Siti Rohani Binti Mohd Yakop, Masaki Yamazaki, Yazdan Yazdanpanah, Nicholas Yee Liang Hing, Cécile Yelnik, Chian Hui Yeoh, Stephanie Yerkovich, Touxiong Yiaye, Toshiki Yokoyama, Hodane Yonis, Obada Yousif, Saptadi Yuliarto, Akram Zaaqoq, Marion Zabbe, Kai Zacharowski, Masliza Zahid, Maram Zahran, Nor Zaila Binti Zaidan, Maria Zambon, Miguel Zambrano, Alberto Zanella, Konrad Zawadka, Nurul Zaynah, Hiba Zayyad, Alexander Zoufaly, David Zucman, Durante-Mangoni, Emanuele, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Microbes in Health and Disease (MHD), Garcia-Gallo E., Merson L., Kennon K., Kelly S., Citarella B. W. , Fryer D. V. , Shrapnel S., Lee J., Duque S., Fuentes Y. V. , et al., and Medical Microbiology & Infectious Diseases
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Eğitim ,Social Sciences and Humanities ,Information Security and Reliability ,Social Sciences (SOC) ,Sosyal Bilimler ve Beşeri Bilimler ,Epidemiology ,EDUCATION & EDUCATIONAL RESEARCH ,Temel Bilimler (SCI) ,BİLGİSAYAR BİLİMİ, BİLGİ SİSTEMLERİ ,MATHEMATICS ,Sociology ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Prospective Studies ,COMPUTER SCIENCE, INFORMATION SYSTEMS ,STATISTICS & PROBABILITY ,Matematik ,Bilgisayar Bilimi Uygulamaları ,Computer Sciences ,Bilgi Güvenliği ve Güvenilirliği ,EĞİTİM VE EĞİTİM ARAŞTIRMASI ,BİLGİ BİLİMİ VE KÜTÜPHANE BİLİMİ ,Bilgi sistemi ,Computer Science Applications ,Kütüphane ve Bilgi Bilimleri ,Hospitalization ,Natural Sciences (SCI) ,Physical Sciences ,Engineering and Technology ,Sosyal Bilimler (SOC) ,Bilgisayar Bilimi ,Statistics, Probability and Uncertainty ,Information Systems ,Human ,Statistics and Probability ,Humans ,Pandemics ,SARS-CoV-2 ,COVID-19 ,SOCIAL SCIENCES, GENERAL ,Library and Information Sciences ,Education ,SDG 3 - Good Health and Well-being ,Library Sciences ,INFORMATION SCIENCE & LIBRARY SCIENCE ,İstatistik ve Olasılık ,Sosyal ve Beşeri Bilimler ,Bilgisayar Bilimleri ,Social Sciences & Humanities ,Engineering, Computing & Technology (ENG) ,Sosyoloji ,Pandemic ,İSTATİSTİK & OLASILIK ,Mühendislik, Bilişim ve Teknoloji (ENG) ,İstatistik, Olasılık ve Belirsizlik ,Sosyal Bilimler Genel ,COMPUTER SCIENCE ,Prospective Studie ,Fizik Bilimleri ,Viral infection ,Mühendislik ve Teknoloji ,Kütüphanecilik - Abstract
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World Health Organization Clinical Characterization Protocol and data tools. The database includes data from more than 705,000 patients, collected in more than 60 countries and 1,500 centres worldwide. Patient data are available from acute hospital admissions with COVID-19 and outpatient follow-ups. The data include signs and symptoms, pre-existing comorbidities, vital signs, chronic and acute treatments, complications, dates of hospitalization and discharge, mortality, viral strains, vaccination status, and other data. Here, we present the dataset characteristics, explain its architecture and how to gain access, and provide tools to facilitate its use., This work is part of the Grand Challenges ICODA pilot initiative, delivered by Health Data Research UK and funded by the Bill & Melinda Gates Foundation and the Minderoo Foundation. The philanthropic support of the donors to the University of Oxford’s COVID-19 Research Response Fund; UK Foreign, Commonwealth and Development Office and Wellcome [215091/Z/18/Z and 220757/Z/20/Z]; the Bill & Melinda Gates Foundation [OPP1209135]; the National Institute for Health Research (NIHR; award CO-CIN-01); the Medical Research Council (MRC; grant MC_PC_19059); the NIHR Health Protection Research Unit (HPRU) in Emerging and Zoonotic Infections at University of Liverpool in partnership with Public Health England (PHE)(award 200907); NIHR HPRU in Respiratory Infections at Imperial College London with PHE (award 200927); Liverpool Experimental Cancer Medicine Centre (grant C18616/A25153); NIHR Biomedical Research Centre at Imperial College London (award IS-BRC-1215-20013); NIHR Clinical Research Network (infrastructure support); CIHR Coronavirus Rapid Research Funding Opportunity OV2170359 and was coordinated out of Sunnybrook Research Institute; the endorsement of the Irish Critical Care- Clinical Trials Group, co-ordinated in Ireland by the Irish Critical Care- Clinical Trials Network at University College Dublin and funded by the Health Research Board of Ireland [CTN-2014-12]; Rapid European COVID-19 Emergency Response research (RECOVER) [H2020 project 101003589]; European Clinical Research Alliance on Infectious Diseases (ECRAID) [965313]; COVID clinical management team, AIIMS, Rishikesh, India; Cambridge NIHR Biomedical Research Centre; the dedication and hard work of the Groote Schuur Hospital Covid ICU Team; the Groote Schuur nursing and University of Cape Town registrar bodies coordinated by the Division of Critical Care at the University of Cape Town; Wellcome Trust fellowship [205228/Z/16/Z]; the Liverpool School of Tropical Medicine; the University of Oxford; the dedication and hard work of the Norwegian SARS-CoV-2 study team; the Research Council of Norway grant no 312780; a philanthropic donation from Vivaldi Invest A/S owned by Jon Stephenson von Tetzchner; Innovative Medicines Initiative Joint Undertaking under Grant Agreement No. 115523 COMBACTE, resources of which are composed of financial contribution from the European Union’s Seventh Framework Programme (FP7/2007–2013) and EFPIA companies, in-kind contribution; preparedness work conducted by the Short Period Incidence Study of Severe Acute Respiratory Infection; Stiftungsfonds zur Förderung der Bekämpfung der Tuberkulose und anderer Lungenkrankheiten of the City of Vienna, Project Number: APCOV22BGM; Italian Ministry of Health “Fondi Ricerca corrente–L1P6” to IRCCS Ospedale Sacro Cuore–Don Calabria; Australian Department of Health grant (3273191); Gender Equity Strategic Fund at University of Queensland; Artificial Intelligence for Pandemics (A14PAN) at University of Queensland; the Australian Research Council Centre of Excellence for Engineered Quantum Systems (EQUS, CE170100009); the Prince Charles Hospital Foundation, Australia; UK Medical Research Council Clinical Research Training Fellowship MR/V001671/1; Instituto de Salud Carlos III, Ministerio de Ciencia, Spain; Brazil, National Council for Scientific and Technological Development Scholarship number 303953/2018-7; Firland Foundation, Shoreline, Washington, USA; the French COVID cohort (NCT04262921) is sponsored by INSERM and is funding by the REACTing (REsearch & ACtion emergING infectious diseases) consortium and by a grant of the French Ministry of Health (PHRC n°20-0424).
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- 2022
30. 189 Long-term outcomes of early-onset myocardial infarction with non-obstructive coronary artery disease
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Magnani, Giulia, primary, Bricoli, Serena, additional, Ardissino, Maddalena, additional, Maglietta, Giuseppe, additional, Nelson, Adam, additional, Tagliazzuccchi, Guidoantonio Malagoli, additional, Disisto, Caterina, additional, Celli, Patrizia, additional, Ferrario, Maurizio, additional, Canosi, Umberto, additional, Cernetti, Carlo, additional, Negri, Francesco, additional, Merlini, Piera Angelica, additional, Tubaro, Marco, additional, Berzuini, Carlo, additional, Manzalini, Chiara, additional, Ignone, Giancarlo, additional, Campana, Carlo, additional, Moschini, Luigi, additional, Ponte, Elisabetta, additional, Pozzi, Roberto, additional, Fetiveau, Raffaella, additional, Buratti, Silvia, additional, Paraboschi, Elvezia, additional, Asselta, Rosanna, additional, Botti, Andrea, additional, Tuttolomondo, Domenico, additional, Barocelli, Federico, additional, Biagi, Andrea, additional, Bonura, Rosario, additional, Moccetti, Tiziano, additional, Crocamo, Antonio, additional, Benatti, Giorgio, additional, Paoli, Giorgia, additional, Solinas, Emilia, additional, Notarangelo, Maria Francesca, additional, Moscarella, Elisabetta, additional, Calabrò, Paolo, additional, Duga, Stefano, additional, Niccoli, Giampoalo, additional, and Ardissino, Diego, additional
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- 2021
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31. Surgical Antimicrobial Prophylaxis in Neonates and Children with Special High-Risk Conditions: A RAND/UCLA Appropriateness Method Consensus Study
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Bianchini, Sonia, Rigotti, Erika, Nicoletti, Laura, Monaco, Sara, Auriti, Cinzia, Castagnola, Elio, Castelli Gattinara, Guido, De Luca, Maia, Galli, Luisa, Garazzino, Silvia, La Grutta, Stefania, Lancella, Laura, Lo Vecchio, Andrea, Maglietta, Giuseppe, Montagnani, Carlotta, Petrosillo, Nicola, Pietrasanta, Carlo, Principi, Nicola, Simonini, Alessandra, Tesoro, Simonetta, Venturini, Elisabetta, Piacentini, Giorgio, Lima, Mario, Staiano, Annamaria, Esposito, Susanna, On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Null, Bianchini, Sonia, Rigotti, Erika, Nicoletti, Laura, Monaco, Sara, Auriti, Cinzia, Castagnola, Elio, Castelli Gattinara, Guido, De Luca, Maia, Galli, Luisa, Garazzino, Silvia, La Grutta, Stefania, Lancella, Laura, Lo Vecchio, Andrea, Maglietta, Giuseppe, Montagnani, Carlotta, Petrosillo, Nicola, Pietrasanta, Carlo, Principi, Nicola, Simonini, Alessandra, Tesoro, Simonetta, Venturini, Elisabetta, Piacentini, Giorgio, Lima, Mario, Staiano, Annamaria, Esposito, Susanna, and On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Null
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Microbiology (medical) ,immunosuppression ,multidrug resistant bacteria ,antibiotic allergy ,comorbidity ,MRSA ,MSSA ,splenectomy ,surgical antibiotic prophylaxis ,Keywords: antibiotic allergy ,Biochemistry ,Microbiology ,Infectious Diseases ,Pharmacology (medical) ,General Pharmacology, Toxicology and Pharmaceutics ,surgical antibiotic prophylaxis 1. Introduction - Abstract
Surgical site infections (SSIs), which are a potential complications in surgical procedures, are associated with prolonged hospital stays and increased postoperative mortality rates, and they also have a significant economic impact on health systems. Data in literature regarding risk factors for SSIs in pediatric age are scarce, with consequent difficulties in the management of SSI prophylaxis and with antibiotic prescribing attitudes in the various surgical procedures that often tend to follow individual opinions. The lack of pediatric studies is even more evident when we consider surgeries performed in subjects with underlying conditions that may pose an increased risk of complications. In order to respond to this shortcoming, we developed a consensus document to define optimal surgical antimicrobial prophylaxis (SAP) in neonates and children with specific high-risk conditions. These included the following: (1) colonization by methicillin-resistant Staphylococcus aureus (MRSA) and by multidrug resistant (MDR) bacteria other than MRSA; (2) allergy to first-line antibiotics; (3) immunosuppression; (4) splenectomy; (5) comorbidity; (6) ongoing antibiotic therapy or prophylaxis; (7) coexisting infection at another site; (8) previous surgery in the last month; and (9) presurgery hospitalization lasting more than 2 weeks. This work, made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies, represents, in our opinion, the most up-to-date and comprehensive collection of recommendations relating to behaviors to be undertaken in a perioperative site in the presence of specific categories of patients at high-risk of complications during surgery. The application of uniform and shared protocols in these high-risk categories will improve surgical practice with a reduction in SSIs and consequent rationalization of resources and costs, as well as being able to limit the phenomenon of antimicrobial resistance.
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- 2022
32. Presence and activities of clinical research coordinators at Italian Health Care Institutions: A national cross-sectional survey
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Caminiti, Caterina, primary, Maglietta, Giuseppe, additional, Frau, Ileana, additional, Peruzzotti, Giulia, additional, Felisi, Mariagrazia, additional, and van Dijk, Antoinette, additional
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- 2021
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33. Effectiveness of a Psychosocial Care Quality Improvement Strategy to Address Quality of Life in Patients With Cancer
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Caminiti, Caterina, primary, Annunziata, Maria Antonietta, additional, Verusio, Claudio, additional, Pinto, Carmine, additional, Airoldi, Mario, additional, Aragona, Marcello, additional, Caputo, Francesca, additional, Cinieri, Saverio, additional, Giordani, Paolo, additional, Gori, Stefania, additional, Mattioli, Rodolfo, additional, Novello, Silvia, additional, Pazzola, Antonio, additional, Procopio, Giuseppe, additional, Russo, Antonio, additional, Sarobba, Giuseppina, additional, Zerilli, Filippo, additional, Diodati, Francesca, additional, Iezzi, Elisa, additional, Maglietta, Giuseppe, additional, and Passalacqua, Rodolfo, additional
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- 2021
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34. Biological Role and Clinical Implications of microRNAs in BRCA Mutation Carriers
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Tommasi, Chiara, primary, Pellegrino, Benedetta, additional, Boggiani, Daniela, additional, Sikokis, Angelica, additional, Michiara, Maria, additional, Uliana, Vera, additional, Bortesi, Beatrice, additional, Bonatti, Francesco, additional, Mozzoni, Paola, additional, Pinelli, Silvana, additional, Squadrilli, Anna, additional, Viani, Maria Vittoria, additional, Cassi, Diana, additional, Maglietta, Giuseppe, additional, Meleti, Marco, additional, and Musolino, Antonino, additional
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- 2021
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35. Surgical Antimicrobial Prophylaxis in Neonates and Children Undergoing Neurosurgery: A RAND/UCLA Appropriateness Method Consensus Study.
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Esposito, Susanna, Zucchelli, Mino, Bianchini, Sonia, Nicoletti, Laura, Monaco, Sara, Rigotti, Erika, Venditto, Laura, Auriti, Cinzia, Caminiti, Caterina, Castagnola, Elio, Conti, Giorgio, De Luca, Maia, Donà, Daniele, Galli, Luisa, Garazzino, Silvia, La Grutta, Stefania, Lancella, Laura, Lima, Mario, Maglietta, Giuseppe, and Pelizzo, Gloria
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CRANIOTOMY ,NEUROSURGERY ,SURGICAL anastomosis ,SURGICAL site infections ,SPINAL surgery ,NEWBORN infants - Abstract
Pediatric neurosurgery is a highly specialized branch of surgery in which surgical site infections (SSIs) are potentially serious complications that can also adversely affect a good surgical outcome, compromising functional recovery and, in some cases, even putting the patient's life at risk. The main aim of this consensus document is to provide clinicians with a series of recommendations on antimicrobial prophylaxis for neonates and children undergoing neurosurgery. The following scenarios were considered: (1) craniotomy or cranial/cranio-facial approach to craniosynostosis; (2) neurosurgery with a trans-nasal-trans-sphenoidal approach; (3) non-penetrating head injuries; (4) penetrating head fracture; (5) spinal surgery (extradural and intradural); (6) shunt surgery or neuroendoscopy; (7) neuroendovascular procedures. Patients undergoing neurosurgery often undergo peri-operative antibiotic prophylaxis, with different schedules, not always supported by scientific evidence. This consensus provides clear and shared indications, based on the most updated literature. This work has been made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies, and represents, in our opinion, the most complete and up-to-date collection of recommendations on the behavior to be held in the peri-operative setting in this type of intervention, in order to guide physicians in the management of the patient, standardize approaches and avoid abuse and misuse of antibiotics. [ABSTRACT FROM AUTHOR]
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36. Effects of the COVID-19 Epidemic on Hospital Admissions for Non-Communicable Diseases in a Large Italian University-Hospital: A Descriptive Case-Series Study
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Caminiti, Caterina, primary, Maglietta, Giuseppe, additional, Meschi, Tiziana, additional, Ticinesi, Andrea, additional, Silva, Mario, additional, and Sverzellati, Nicola, additional
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- 2021
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37. Abstract PS4-33: Androgen receptors are highly expressed in HER2-positive breast cancers that achieve pCR to anti-HER2 monoclonal antibodies
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Pellegrino, Benedetta, primary, Campanini, Nicoletta, additional, Boggiani, Daniela, additional, Zanoni, Daniele, additional, Sikokis, Angelica, additional, Missale, Gabriele, additional, Maglietta, Giuseppe, additional, Frassoldati, Antonio, additional, Michiara, Maria, additional, Silini, Enrico Maria, additional, and Musolino, Antonino, additional
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- 2021
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38. Long-Term Outcomes After Early-Onset Myocardial Infarction
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Maglietta, Giuseppe, Ardissino, Maddalena, Malagoli Tagliazucchi, Guidantonio, Disisto, Caterina, Merlini, Piera Angelica, Crocamo, Antonio, Notarangelo, Maria Francesca, Calabrò, Paolo, Berzuini, Carlo, and Ardissino, Diego
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- 2019
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39. SEX-BASED DIFFERENCES IN LONG-TERM OUTCOMES AFTER EARLY-ONSET MYOCARDIAL INFARCTION
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Ardissino, Maddalena, primary, Nelson, Adam J., additional, Maglietta, Giuseppe, additional, Tagliazucchi, Guidantonio Malagoli, additional, Disisto, Caterina, additional, Canosi, Umberto, additional, Cernetti, Carlo, additional, Merlini, Piera Angelica, additional, Berzuini, Carlo, additional, Ponte, Elisabetta, additional, Fetiveau, Raffaella, additional, Buratti, Silvia, additional, Paraboschi, Elvezia, additional, Duga, Stefano, additional, Tuttolomondo, Domenico, additional, Crocamo, Antonio, additional, Barocelli, Federico, additional, Bricoli, Serena, additional, Botti, Andrea, additional, Bonura, Rosario, additional, Magnani, Giulia, additional, Biagi, Andrea, additional, Paoli, Giorgia, additional, Solinas, Emilia, additional, and Ardissino, Diego, additional
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- 2020
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40. Abstract P1-18-19: Phase II, open label, randomized, biomarker study of immune-mediated mechanism of action of neoadjuvant subcutaneous trastuzumab in patients with operable, locally advanced, or inflammatory HER2-positive breast cancer. ImmunHER trial on behalf of the Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC)
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Musolino, Antonino, primary, Gori, Stefania, additional, Cretella, Elisabetta, additional, Marabese, Alessandra, additional, Cavanna, Luigi, additional, Frassoldati, Antonio, additional, Bisagni, Giancarlo, additional, Casarini, Chiara, additional, Bria, Emilio, additional, Carbognin, Luisa, additional, Fiorio, Elena, additional, Brandes, Alba A, additional, Zamagni, Claudio, additional, Gianni, Lorenzo, additional, Zambelli, Alberto, additional, Montemurro, Filippo, additional, Tognetto, Michele, additional, Todeschini, Renata, additional, Maglietta, Giuseppe, additional, Missale, Gabriele, additional, and Silini, Enrico M, additional
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- 2020
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41. Presence and activities of clinical research coordinators at Italian Health Care Institutions: A national cross-sectional survey.
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Caminiti, Caterina, Maglietta, Giuseppe, Frau, Ileana, Peruzzotti, Giulia, Felisi, Mariagrazia, and van Dijk, Antoinette
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HEALTH facilities ,CLINICAL trials ,MEDICAL research ,RESEARCH teams ,SERVER farms (Computer network management) ,MULTIVARIABLE testing - Abstract
Background: Clinical Research Coordinators (CRCs) are key members of research teams who ensure rigorous conduction of clinical studies and quality standard compliance. Yet, their roles and responsibilities are still not well defined, and formal recognition of their professional profile is lacking in Italy. This survey of Italian healthcare institutions collected data on centers' research activities number of CRCs and tasks they performed and explored factors associated with CRC employment. Methods: Cross-sectional study using a brief questionnaire. Data were analyzed by means of graphical representations, histogram, scatter, and polar plots. Multivariable linear regression was specified to test the association between the number of CRCs and a subset of factors. Results: Data collection took place from February to December 2020. 62/143 institutions (43.4%) responded. Median number of ongoing studies reported by centers was 65 (IQR 29–205); of these, median of sponsored and interventional studies was 32 and 35, respectively. Median number of CRCs employed at each center was 6 (IQR 2–9). The frequency with which activities were reported to be performed by CRCs overlapped with those of Data Managers. Linear multivariable regression analysis revealed a statistically significant association between the number of employed CRCs and the number of sponsored studies (P = 0.01), but not with the total number of studies, geographical location, or institution type. Conclusions: The association between industry funding and the number of CRCs observed in this study should be further explored to understand the direction of this relationship and to verify whether this may influence compliance with quality standards. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
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42. Early palliative care and quality of life of advanced cancer patients—a multicenter randomized clinical trial
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Franciosi, Vittorio, primary, Maglietta, Giuseppe, additional, Esposti, Claudia Degli, additional, Caruso, Giuseppe, additional, Cavanna, Luigi, additional, Bertè, Raffaella, additional, Bacchini, Gianpaolo, additional, Bocchi, Letizia, additional, Piva, Erico, additional, Monfredo, Michela, additional, Scafuri, Valentina, additional, Di Cesare, Pamela, additional, Melotti, Barbara, additional, Sequino, Manuel, additional, Rimanti, Anita, additional, Binovi, Cinzia, additional, Ghisoni, Francesco, additional, and Caminiti, Caterina, additional
- Published
- 2019
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43. Modified dose-dense taxotere cisplatin fluorouracil regimen (mTCF-dd) in a large cohort of patients (pts) with metastatic or locally advanced non-squamous gastroesophageal cancer (GEC).
- Author
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Toppo, Laura, primary, Tomasello, Gianluca, additional, Liguigli, Wanda, additional, Lazzarelli, Silvia, additional, Tanzi, Giulia, additional, Ghidini, Michele, additional, Perrucci, Bruno, additional, Brighenti, Matteo, additional, Ratti, Margherita, additional, Panni, Stefano, additional, Giganti, Maria Olga, additional, Donini, Maddalena, additional, Rovatti, Massimo, additional, Maglietta, Giuseppe, additional, Ranieri, Valerio, additional, Grassia, Roberto, additional, Iiritano, Elena, additional, Iezzi, ELISA, additional, Caminiti, Caterina, additional, and Passalacqua, Rodolfo, additional
- Published
- 2016
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44. Prognostic role of TP53 variants in the phase III study of FOLFIRI/cetuximab versus FOLFIRI/cetuximab followed by cetuximab (Cet) alone in first-line therapy of patients with RAS and BRAF wild-type (wt) metastatic colorectal cancer (mCRC) (ERMES study).
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Normanno, Nicola, Orlandi, Armando, Maiello, Evaristo, Rachiglio, Anna Maria, Maglietta, Giuseppe, Damato, Angela, Calegari, Maria Alessandra, Antonuzzo, Lorenzo, Bordonaro, Roberto, Zampino, Maria Giulia, Tamberi, Stefano, Lonardi, Sara, Tonini, Giuseppe, Rosati, Gerardo, Latiano, Tiziana Pia, Tamburini, Emiliano, Maiello, Monica Rosaria, Carotenuto, Marianeve, Barone, Carlo, and Pinto, Carmine
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- 2023
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45. Retrospective 8-Year Study on the Antibiotic Resistance of Uropathogens in Children Hospitalised for Urinary Tract Infection in the Emilia-Romagna Region, Italy.
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Esposito, Susanna, Maglietta, Giuseppe, Di Costanzo, Margherita, Ceccoli, Martina, Vergine, Gianluca, La Scola, Claudio, Malaventura, Cristina, Falcioni, Alice, Iacono, Alessandra, Crisafi, Antonella, Iughetti, Lorenzo, Conte, Maria Luisa, Pierantoni, Luca, Gatti, Claudia, Caminiti, Caterina, and Biasucci, Giacomo
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URINARY tract infections ,DRUG resistance in bacteria ,TREATMENT failure ,CHILD patients ,ANTIBIOTICS - Abstract
The development and spread of antibiotic resistance is an increasingly important global public health problem, even in paediatric urinary tract infection (UTI). In light of the variability in the data, it is necessary to conduct surveillance studies to determine the prevalence of antibiotic resistance in specific geographical areas to optimize therapeutic management. In this observational, retrospective, multicentre study, the medical records of 1801 paediatric patients who were hospitalised for UTI between 1 January 2012, and 30 June 2020, in Emilia-Romagna, Italy, were analysed. Escherichia coli was the most frequently detected pathogen (75.6%), followed by Klebsiella pneumoniae (6.9%) and Pseudomonas aeruginosa (2.5%). Overall, 840 cases (46.7%) were due to antimicrobial-resistant uropathogens: 83 (4.7%) extended spectrum beta-lactamase (ESBL)-producing, 119 (6.7%) multidrug resistant (MDR) and 4 (0.2%) extensively drug resistant (XDR) bacteria. Empirical antibiotic therapy failed in 172 cases (9.6%). Having ESBL or MDR/XDR uropathogens, a history of recurrent UTI, antibiotic therapy in the preceding 30 days, and empirical treatment with amoxicillin or amoxicillin/clavulanate were significantly associated with treatment failure, whereas first-line therapy with third-generation cephalosporins was associated with protection against negative outcomes. In conclusion, the increase in the resistance of uropathogens to commonly used antibiotics requires continuous monitoring, and recommendations for antibiotic choice need updating. In our epidemiological context, amoxicillin/clavulanate no longer seems to be the appropriate first-line therapy for children hospitalised for UTI, whereas third-generation cephalosporins continue to be useful. To further limit the emergence of resistance, every effort to reduce and rationalise antibiotic consumption must be implemented. [ABSTRACT FROM AUTHOR]
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- 2021
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46. Surgical Antimicrobial Prophylaxis in Neonates and Children Undergoing Neurosurgery: A RAND/UCLA Appropriateness Method Consensus Study
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Susanna, Esposito, Mino, Zucchelli, Sonia, Bianchini, Laura, Nicoletti, Sara, Monaco, Erika, Rigotti, Laura, Venditto, Cinzia, Auriti, Caterina, Caminiti, Elio, Castagnola, Giorgio, Conti, Maia, De Luca, Daniele, Donà, Luisa, Galli, Silvia, Garazzino, Stefania, La Grutta, Laura, Lancella, Mario, Lima, Giuseppe, Maglietta, Gloria, Pelizzo, Nicola, Petrosillo, Giorgio, Piacentini, Simone, Pizzi, Alessandro, Simonini, Simonetta, Tesoro, Elisabetta, Venturini, Fabio, Mosca, Annamaria, Staiano, Nicola, Principi, On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Esposito, Susanna, Zucchelli, Mino, Bianchini, Sonia, Nicoletti, Laura, Monaco, Sara, Rigotti, Erika, Venditto, Laura, Auriti, Cinzia, Caminiti, Caterina, Castagnola, Elio, Conti, Giorgio, De Luca, Maia, Donà, Daniele, Galli, Luisa, Garazzino, Silvia, La Grutta, Stefania, Lancella, Laura, Lima, Mario, Maglietta, Giuseppe, Pelizzo, Gloria, Petrosillo, Nicola, Piacentini, Giorgio, Pizzi, Simone, Simonini, Alessandro, Tesoro, Simonetta, Venturini, Elisabetta, Mosca, Fabio, Staiano, Annamaria, Principi, Nicola, and On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Null
- Subjects
Microbiology (medical) ,craniotomy ,Biochemistry ,Microbiology ,pediatric infectious disease ,Infectious Diseases ,surgical antibiotic prophylaxis ,antibiotics ,head fracture ,pediatric infectious diseases ,neurosurgery ,antibiotic ,Pharmacology (medical) ,General Pharmacology, Toxicology and Pharmaceutics ,Keywords: antibiotic - Abstract
Pediatric neurosurgery is a highly specialized branch of surgery in which surgical site infections (SSIs) are potentially serious complications that can also adversely affect a good surgical outcome, compromising functional recovery and, in some cases, even putting the patient’s life at risk. The main aim of this consensus document is to provide clinicians with a series of recommendations on antimicrobial prophylaxis for neonates and children undergoing neurosurgery. The following scenarios were considered: (1) craniotomy or cranial/cranio-facial approach to craniosynostosis; (2) neurosurgery with a trans-nasal-trans-sphenoidal approach; (3) non-penetrating head injuries; (4) penetrating head fracture; (5) spinal surgery (extradural and intradural); (6) shunt surgery or neuroendoscopy; (7) neuroendovascular procedures. Patients undergoing neurosurgery often undergo peri-operative antibiotic prophylaxis, with different schedules, not always supported by scientific evidence. This consensus provides clear and shared indications, based on the most updated literature. This work has been made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies, and represents, in our opinion, the most complete and up-to-date collection of recommendations on the behavior to be held in the peri-operative setting in this type of intervention, in order to guide physicians in the management of the patient, standardize approaches and avoid abuse and misuse of antibiotics.
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- 2022
47. Sex-Related Differences in Long-Term Outcomes After Early-Onset Myocardial Infarction
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Maddalena Ardissino, Adam J. Nelson, Giuseppe Maglietta, Guidantonio Malagoli Tagliazucchi, Caterina Disisto, Patrizia Celli, Maurizio Ferrario, Umberto Canosi, Carlo Cernetti, Francesco Negri, Piera Angelica Merlini, Marco Tubaro, Carlo Berzuini, Chiara Manzalini, Gianfranco Ignone, Carlo Campana, Luigi Moschini, Elisabetta Ponte, Roberto Pozzi, Raffaela Fetiveau, Silvia Buratti, Elvezia Maria Paraboschi, Rosanna Asselta, Andrea Botti, Domenico Tuttolomondo, Federico Barocelli, Serena Bricoli, Andrea Biagi, Rosario Bonura, Tiziano Moccetti, Antonio Crocamo, Giorgio Benatti, Giorgia Paoli, Emilia Solinas, Maria Francesca Notarangelo, Elisabetta Moscarella, Paolo Calabrò, Stefano Duga, Giulia Magnani, Diego Ardissino, Ardissino, Maddalena, Nelson, Adam J, Maglietta, Giuseppe, Malagoli Tagliazucchi, Guidantonio, Disisto, Caterina, Celli, Patrizia, Ferrario, Maurizio, Canosi, Umberto, Cernetti, Carlo, Negri, Francesco, Merlini, Piera Angelica, Tubaro, Marco, Berzuini, Carlo, Manzalini, Chiara, Ignone, Gianfranco, Campana, Carlo, Moschini, Luigi, Ponte, Elisabetta, Pozzi, Roberto, Fetiveau, Raffaela, Buratti, Silvia, Paraboschi, Elvezia Maria, Asselta, Rosanna, Botti, Andrea, Tuttolomondo, Domenico, Barocelli, Federico, Bricoli, Serena, Biagi, Andrea, Bonura, Rosario, Moccetti, Tiziano, Crocamo, Antonio, Benatti, Giorgio, Paoli, Giorgia, Solinas, Emilia, Notarangelo, Maria Francesca, Moscarella, Elisabetta, Calabrò, Paolo, Duga, Stefano, Magnani, Giulia, and Ardissino, Diego
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myocardial infarction ,baseline risk difference ,young ,long term outcome ,gender ,Cardiology and Cardiovascular Medicine - Abstract
ImportanceThere is growing awareness of sex-related differences in cardiovascular risk profiles, but less is known about whether these extend to pre-menopausal females experiencing an early-onset myocardial infarction (MI), who may benefit from the protective effects of estrogen exposure.MethodsA nationwide study involving 125 Italian Coronary Care Units recruited 2,000 patients between 1998 and 2002 hospitalized for a type I myocardial infarction before the age of 45 years (male, n = 1,778 (88.9%). Patients were followed up for a median of 19.9 years (IQR 18.1–22.6). The primary composite endpoint was the occurrence of cardiovascular death, non-fatal myocardial re-infarction or non-fatal stroke, and the secondary endpoint of hospitalization for revascularisation by means of a percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG).ResultsST-elevation MI was the most frequent presentation among both men and women (85.1 vs. 87.4%, p = ns), but the men had a greater baseline coronary atherosclerotic burden (median Duke Coronary Artery Disease Index: 48 vs. 23; median Syntax score 9 vs. 7; both p < 0.001). The primary composite endpoint occurred less frequently among women (25.7% vs. 37.0%; adjusted hazard ratio: 0.69, 95% CI 0.52–0.91; p = 0.01) despite being less likely to receive treatment with most secondary prevention medications during follow up.ConclusionsThere are significant sex-related differences in baseline risk factors and outcomes among patients with early-onset MI: women present with a lower atherosclerotic disease burden and, although they are less frequently prescribed secondary prevention measures, experience better long-term outcomes.Trial Registration4272/98 Ospedale Niguarda, Ca' Granda 03/09/1998.
- Published
- 2022
48. Surgical Antimicrobial Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Eye Surgery: A RAND/UCLA Appropriateness Method Consensus Study
- Author
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Sonia, Bianchini, Chiara, Morini, Laura, Nicoletti, Sara, Monaco, Erika, Rigotti, Caterina, Caminiti, Giorgio, Conti, Maia, De Luca, Daniele, Donà, Giuseppe, Maglietta, Laura, Lancella, Andrea, Lo Vecchio, Giorgio, Marchini, Carlo, Pietrasanta, Nicola, Principi, Alessandro, Simonini, Elisabetta, Venturini, Rosa, Longo, Elena, Gusson, Domenico, Boccuzzi, Luca, Vigo, Fabio, Mosca, Annamaria, Staiano, Susanna, Esposito, On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Bianchini, Sonia, Morini, Chiara, Nicoletti, Laura, Monaco, Sara, Rigotti, Erika, Caminiti, Caterina, Conti, Giorgio, De Luca, Maia, Donà, Daniele, Maglietta, Giuseppe, Lancella, Laura, Lo Vecchio, Andrea, Marchini, Giorgio, Pietrasanta, Carlo, Principi, Nicola, Simonini, Alessandro, Venturini, Elisabetta, Longo, Rosa, Gusson, Elena, Boccuzzi, Domenico, Vigo, Luca, Mosca, Fabio, Staiano, Annamaria, Esposito, Susanna, and On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group, Null
- Subjects
Microbiology (medical) ,Settore MED/38 - Pediatria Generale e Specialistica ,genetic structures ,antibiotics ,eye ,pediatric infectious diseases ,pediatric ophthalmology ,ocular surgery ,surgical antimicrobial prophylaxis ,Biochemistry ,Microbiology ,eye diseases ,pediatric infectious disease ,Infectious Diseases ,Antibiotics ,antibiotic ,Settore MED/41 - ANESTESIOLOGIA ,Pharmacology (medical) ,sense organs ,General Pharmacology, Toxicology and Pharmaceutics - Abstract
Ocular surgery encompasses a wide range of procedures, including surgery of the tear ducts, eyelid, cornea and conjunctiva, lens, ocular muscle, and vitreoretinal and iris surgery. Operations are also performed for the removal of tumors, repairs of ocular trauma and, finally, corneal transplantation. Antibiotic prophylaxis for the prevention of surgical site infections (SSIs) in ocular surgery is a complex field in which shared lines of action are absent. In light of the scarcity of shared evidence in the use of ocular antimicrobial prophylaxis for the pediatric population, this consensus document aims to provide clinicians with a series of recommendations on antimicrobial prophylaxis for patients of neonatal and pediatric age undergoing eye surgery. The following scenarios are considered: (1) intraocular surgery; (2) extraocular surgery; (3) ocular trauma; (4) ocular neoplasm; (5) ocular surface transplantations; (6) corneal grafts. This work has been made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies and represents, in our opinion, the most complete and up-to-date collection of recommendations regarding clinical actions in the peri-operative environment in eye surgery. The application of uniform and shared protocols aims to improve surgical practice, through the standardization of procedures, with a consequent reduction of SSIs, also limiting the phenomenon of antimicrobial resistance.
- Published
- 2022
49. Il servizio sanitario ha bisogno di personale competente in ricerca?
- Author
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Caminiti C, Maglietta G, Puntoni M, Diodati F, Marcomini B, Lazzarelli S, and Rossolini V
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- Humans, Health Services
- Published
- 2023
- Full Text
- View/download PDF
50. Surgical Antimicrobial Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Eye Surgery: A RAND/UCLA Appropriateness Method Consensus Study.
- Author
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Bianchini S, Morini C, Nicoletti L, Monaco S, Rigotti E, Caminiti C, Conti G, De Luca M, Donà D, Maglietta G, Lancella L, Lo Vecchio A, Marchini G, Pietrasanta C, Principi N, Simonini A, Venturini E, Longo R, Gusson E, Boccuzzi D, Vigo L, Mosca F, Staiano A, Esposito S, and On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group
- Abstract
Ocular surgery encompasses a wide range of procedures, including surgery of the tear ducts, eyelid, cornea and conjunctiva, lens, ocular muscle, and vitreoretinal and iris surgery. Operations are also performed for the removal of tumors, repairs of ocular trauma and, finally, corneal transplantation. Antibiotic prophylaxis for the prevention of surgical site infections (SSIs) in ocular surgery is a complex field in which shared lines of action are absent. In light of the scarcity of shared evidence in the use of ocular antimicrobial prophylaxis for the pediatric population, this consensus document aims to provide clinicians with a series of recommendations on antimicrobial prophylaxis for patients of neonatal and pediatric age undergoing eye surgery. The following scenarios are considered: (1) intraocular surgery; (2) extraocular surgery; (3) ocular trauma; (4) ocular neoplasm; (5) ocular surface transplantations; (6) corneal grafts. This work has been made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies and represents, in our opinion, the most complete and up-to-date collection of recommendations regarding clinical actions in the peri-operative environment in eye surgery. The application of uniform and shared protocols aims to improve surgical practice, through the standardization of procedures, with a consequent reduction of SSIs, also limiting the phenomenon of antimicrobial resistance.
- Published
- 2022
- Full Text
- View/download PDF
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