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5. Surgery for benign insulinoma: An international review

Author

Rothmund, Matthias, Angelini, Lucio, Brunt, L. Michael, Farndon, John R., Geelhoed, Glenn, Grama, Dimitrie, Herfarth, Christian, Kaplan, Edwin L., Largiader, Felix, Morino, Francesco, Peiper, Hans-Jürgen, Proye, Charles, Röher, Hans-Dietrich, Rückert, Klaus, Kümmerle, Fritz, Thompson, Norman W., and van Heerden, Jon A.

Published
1990
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6. Insulinomi

Author

Morino, Francesco and Toppino, Mauro

Published
2003

7. Surgery for benign insulinoma: An international review

Author

Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Surgery, Philipps-University, Baidingerstra??e, 3550, Marburg/Lahn, Federal Republic of Germany; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Ann Arbor, Herfarth, Christian, K??mmerle, Fritz, R??her, Hans-Dietrich, Geelhoed, Glenn W., Rothmund, Matthias, Heerden, Jon A., Angelini, Lucio, Thompson, Norman W., Morino, Francesco, R??ckert, Klaus, Largiader, Felix, Grama, Dimitrie, Proye, Charles, Peiper, Hans-J??rgen, Kaplan, Edwin L., Brunt, L. Michael, Farndon, John R., Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Surgery, Philipps-University, Baidingerstra??e, 3550, Marburg/Lahn, Federal Republic of Germany; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Ann Arbor, Herfarth, Christian, K??mmerle, Fritz, R??her, Hans-Dietrich, Geelhoed, Glenn W., Rothmund, Matthias, Heerden, Jon A., Angelini, Lucio, Thompson, Norman W., Morino, Francesco, R??ckert, Klaus, Largiader, Felix, Grama, Dimitrie, Proye, Charles, Peiper, Hans-J??rgen, Kaplan, Edwin L., Brunt, L. Michael, and Farndon, John R.

Abstract

In a multiinstitutional review, data on 396 patients with benign solitary or multiple insulinomas operated on in 15 centers were collected. In these 396 patients, 419 laparotomies (375 primary procedures and 44 reoperations) were performed. The rate of unnecessary laparotomies was 1.7%. Complications occurred after 132 operations (31.5%), requiring 27 reinterventions (6.4%). Ten (2%) patients died within 30 days of surgery. The success rate of first procedures in the centers was 94.9%. After reoperation, all but 2 (99.5%) of these patients were cured. The overall cure rate including those patients who had their primary operations elsewhere was 97.5% . Compilant les dossiers de 15??tablissements internationaux, nous avons collig?? les donn??es concernant 396 patients pr??sentant un insulinome b??nin unique ou multiple, op??r??s. Chez ces 396 patients, 419 laparotomies (375 interventions de premi??re intention et 44 reprises) ont??t?? effectu??es. Le taux de laparotomie inutile??tait de 1.7%. Des complications sont intervenues?? la suite de 132 op??rations (31.5%), n??cessitant 27 r??interventions (6.4%). Dix (2%) patients sont morts dans les trente jours apr??s l'acte chirurgical. Le taux de succ??s des interventions de premi??re intention dans les centres de l'??tude??tait de 94.9%. Apr??s r??interventions, tous les patients sauf 2 (99.5%) ont??t?? gu??ris. Le taux global de gu??rison, y compris les patients ayant??t?? op??r??s une premi??re fois ailleurs,??tait de 97.5%. En una revisi??n multiinstitucional se recolectaron los datos sobre 396 pacientes con insulinomas benignos solitarios o m??ltiples operados en 15 centros. En estos 396 pacientes se efectuaron 419 laparotom??as (375 procedimientos primarios y 44 reoperaciones). Se registr?? una tasa de laparotom??as innecesarias de 1.7%; se presentaron complicaciones despu??s de 132 operaciones (31.5%), las cuales requirieron 27 reintervenciones (6.4%). Diez (2%) pacientes murieron dentro de los primeras 30

Published
2006

8. Abdominal aortic aneurysm and concomitant malignancy: what treatment?

Author

Suffat LP, Guffanti P, Rebecchi F, Suffat PP, and Morino F

Subjects
Aged, Female, Humans, Male, Middle Aged, Risk Factors, Aortic Aneurysm, Abdominal complications, Aortic Aneurysm, Abdominal therapy, Neoplasms complications
Abstract

Unlabelled: The association of neoplasm and abdominal aortic aneurysm (AAA), although rare, may represents a therapeutic dilemma., Materials and Methods: Between January 1990 and December 2004 in our departement 127 patients were submitted because of an AAA, in 8 cases there was an association with a neoplasm, in the greater part being a colon cancer. In 3 cases we performed a one stage surgery, in 1 case the chose was for a two stage surgery, for 3 patients we opted for an endovascular treatment by an endograft, in 1 case a pancreatic cancer was diagnosed 3 months after the prosthetic replacement of an AAA and there were no surgical indications because of the patient was in an advanced neoplastic stage., Results: There weren't any prosthetic infection or more serious complications. The endovascular treatments were performed successfully without complications after few days being followed by cancer's resection., Discussion: In case of this association the prognosis is related to neoplasm's stage. Timing depednds on the pathology that has the higher risk of short-term complication. Since Nineties author's reports in Literature about one stage surgery are more frequent, while now endovascular methods open new chances., Conclusions: One stage surgery is a safe option in case of association between AAA and cancer. We think that a good porpouse is the use of a vascular endograft in aneurysmal treatment followed, after few days, by cancer's resection.

Published
2006

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