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Objective: To determine if 2-DeNT Oral Topical Powder is an effective treatment for traumatic oral ulcers. Materials and Methods: Of the 46 patients who were randomly allocated, 20 patients from the experimental group and 17 from the placebo control group completed the study. The patients, operators, and evaluators were all blinded. Patients applied the powder twice a day and completed a diary twice a day for 10 days. The diary was used to monitor the size of the lesions and pain levels (using a 10-cm visual analog scale). Results: By day 5, the ulcers in the experimental group had reduced in size by approximately 70%; and ulcers in the control group had reduced in size by 56%. The experimental-group ulcers were significantly (P < .05) smaller than the control-group ulcers from day 5 through day 9. Ulcers in the experimental group were completely resolved by day 8, whereas control-group ulcers were still present on day 10. Patients experienced a significant amount of stimulated pain until the night of day 2 in the experimental group and until the night of day 5 in the control group, but group differences in pain were not statistically significant. Conclusions: The 2DeNT Oral Topical powder was more effective than the placebo powder at accelerating the healing of oral traumatic ulcers. [ABSTRACT FROM AUTHOR]

Hypercementosis is an abnormal thickening of the cementum. Although the etiology of this condition is uncertain, it occasionally is related to disorders of bone metabolism, including Paget disease and hyperthyroidism. The case presented here illustrates localized idiopathic deposition of excess cementum at the apex of the distal root of a mandibular first molar.

In recent years there has been an overall decrease in cancers of the oral cavity, and a concurrent increase in cancers in specific sites of the posterior oral cavity and oropharynx in the United States. There is increasing evidence that the human papillomavirus may play a role in the development of oropharyngeal squamous cell carcinoma. In this article we review the biology and risk factors associated with HPV and oropharyngeal carcinoma, and recent data suggesting that this type of cancer may be unique in its response to treatment and prognosis.