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1. Persistent Secondary Hyperparathyroidism and Vertebral Fractures in Kidney Transplantation: Role of Calcium-Sensing Receptor Polymorphisms and Vitamin D Deficiency.

Author

Giannini, Sandro, Sella, Stefania, Netto, Fatima Silva, Cattelan, Catia, Carbonare, Luca Dalle, Lazzarin, Roberta, Marchini, Francesco, Rigotti, Paolo, Marcocci, Claudio, Cetani, Filomena, Pardi, Elena, D'Angelo, Angela, Realdi, Giuseppe, and Bonfante, Luciana

Abstract

The article discusses the result of a study which investigated the role of vitamin D deficiency and calcium-sensing receptor polymorphisms in persistent vertebral fractures and secondary hyperparathyroidism (SHPT) in kidney transplantation. It was found that low 25-vitamin D is involved in the pathogenesis of SHPT and it is a common feature after kidney transplantation. The study also suggests that high parathyroid hormone level is associated with an increased risk for vertebral fractures.

Published
2010
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