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263 results on '"Noguchi, Kazuma"'

4. Incidence of antiresorptive agent-related osteonecrosis of the jaw: A multicenter retrospective epidemiological study in Hyogo Prefecture, Japan

Author

Nashi, Masanori, Kishimoto, Hiromitsu, Kobayashi, Masaki, Tachibana, Akira, Suematsu, Motoo, Fujiwara, Shigeyoshi, Ota, Yoshiyuki, Hashitani, Susumu, Shibatsuji, Takeshi, Nishida, Tetsuya, Fujimura, Kazuma, Furudoi, Shungo, Ishida, Yoshiki, Ishii, Shoichiro, Fujita, Tsuyoshi, Iwai, Soichi, Shigeta, Takashi, Harada, Takeshi, Miyai, Daisuke, Takeda, Daisuke, Akashi, Masaya, Noguchi, Kazuma, and Takenobu, Toshihiko

Published
2023
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7. Shotgun metagenomic analysis of saliva microbiome suggests Mogibacterium as a factor associated with chronic bacterial osteomyelitis.

Author

Yahara, Hiroko, Yanamoto, Souichi, Takahashi, Miho, Hamada, Yuji, Asaka, Takuya, Kitagawa, Yoshimasa, Moridera, Kuniyasu, Noguchi, Kazuma, Maruoka, Yutaka, and Yahara, Koji

Subjects
SALIVA analysis, OSTEOMYELITIS, SALIVA, METAGENOMICS, GUT microbiome, SHOTGUN sequencing, SHOTGUNS
Abstract

Osteomyelitis of the jaw is a severe inflammatory disorder that affects bones, and it is categorized into two main types: chronic bacterial and nonbacterial osteomyelitis. Although previous studies have investigated the association between these diseases and the oral microbiome, the specific taxa associated with each disease remain unknown. In this study, we conducted shotgun metagenome sequencing (≥10 Gb from ≥66,395,670 reads per sample) of bulk DNA extracted from saliva obtained from patients with chronic bacterial osteomyelitis (N = 5) and chronic nonbacterial osteomyelitis (N = 10). We then compared the taxonomic composition of the metagenome in terms of both taxonomic and sequence abundances with that of healthy controls (N = 5). Taxonomic profiling revealed a statistically significant increase in both the taxonomic and sequence abundance of Mogibacterium in cases of chronic bacterial osteomyelitis; however, such enrichment was not observed in chronic nonbacterial osteomyelitis. We also compared a previously reported core saliva microbiome (59 genera) with our data and found that out of the 74 genera detected in this study, 47 (including Mogibacterium) were not included in the previous meta-analysis. Additionally, we analyzed a core-genome tree of Mogibacterium from chronic bacterial osteomyelitis and healthy control samples along with a reference complete genome and found that Mogibacterium from both groups was indistinguishable at the core-genome and pan-genome levels. Although limited by the small sample size, our study provides novel evidence of a significant increase in Mogibacterium abundance in the chronic bacterial osteomyelitis group. Moreover, our study presents a comparative analysis of the taxonomic and sequence abundances of all genera detected using deep salivary shotgun metagenome data. The distinct enrichment of Mogibacterium suggests its potential as a marker to distinguish between patients with chronic nonbacterial osteomyelitis and chronic bacterial osteomyelitis, particularly at the early stages when differences are unclear. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Management of odontogenic foci of infection (dental caries, periodontal disease and odontogenic infections) in the oral functional management of patients receiving cancer treatments: Guidelines based on a systematic review: A secondary publication...

Author

Kurita, Hiroshi, Umeda, Masahiro, Ueno, Takaaki, Uzawa, Narikazu, Shibuya, Yasuyuki, Nakamura, Norifumi, Nagatsuka, Hitoshi, Hayashi, Takafumi, Mizoguch, Itaru, Tomihara, Kei, Ikegami, Yumiko, Noguchi, Kazuma, Takiguchi, Yuichi, Yamamoto, Nobuyuki, and Sakai, Hironori

Abstract

In cancer treatment, perioperative oral functional management is used as a part of supportive care. Its main objectives are as follows: (1) preventing and reducing adverse events, (2) maintaining or improving nutritional status, (3) improving cancer treatment outcomes, (4) maintaining or improving quality of life, (5) providing high quality medical care through comprehensive oral care, (6) controlling odontogenic foci of infection, and (7) maintaining or improving oral function. A literature search was conducted using the electronic databases of Medical Journal and PubMed. Electronic database searches were performed using various combinations of the following key words: cancer, surgery, treatment, chemotherapy, radiotherapy and dental disease, oral care, oral management, dental intervention, oral health, dental care, and dental management. The selection of literature for inclusion in the review was restricted to dental management of patients receiving cancer treatment. In the course of the literature review, hand searches were also added as needed. The guideline was developed by summarizing the results of the review. Based on a review of the literature on the management of dental foci of infection in the oral functional management of patients undergoing cancer treatment, a guideline was developed by summarizing the results of the review. This report is a secondary publication of our previous review report "J. Stomatol. Soc. 70(4): 279–289. Dec 2021." [ABSTRACT FROM AUTHOR]

Published
2024
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10. Huge glandular odontogenic cyst: Report of a case and use of CRTC1/3-MAML2 fusion gene analysis for diagnosis.

Author

Ohmae, Takayuki, Noguchi, Kazuma, Yamanegi, Koji, Omori, Yuji, Makihara, Yuna, Yoshikawa, Kyohei, Takaoka, Kazuki, Nakano, Yoshiro, and Kishimoto, Hiromitsu

Abstract

Glandular odontogenic cyst (GOC) is a rare odontogenic cyst with aggressive behavior. A 50-year-old Japanese man presented with pain and swelling of the mental region of the mandible. Panoramic radiography showed a clearly bordered radiolucent lesion extending from the alveolar to cortical bone of the mandible. The clinical diagnosis was an odontogenic tumor (e.g., ameloblastoma), and an incisional biopsy was performed. The histopathological diagnosis was GOC, and extirpation and tooth extraction were performed under general anesthesia. Because bone destruction is evident in patients with a huge GOC, it is important to differentiate these cysts from intraosseous mucoepidermoid carcinoma. Therefore, we analyzed the GOC for the presence of the CRTC1/3-MAML2 fusion gene and found it to be negative. The patient had developed no recurrence of the GOC at the time of following. [ABSTRACT FROM AUTHOR]

Published
2024
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11. A Multicenter Retrospective Study of Elective Neck Dissection for T1-2N0M0 Tongue Squamous Cell Carcinoma: Analysis Using Propensity Score-Matching

Author

Otsuru, Mitsunobu, Ota, Yoshihide, Yanamoto, Souichi, Okura, Masaya, Umeda, Masahiro, Kirita, Tadaaki, Kurita, Hiroshi, Ueda, Michihiro, Komori, Takahide, Yamakawa, Nobuhiro, Kamata, Takahiro, Hasegawa, Takumi, Shibahara, Takahiko, Ohiro, Youichi, Yamashita, Yoshihiro, Noguchi, Kazuma, Noguchi, Tadahide, Karakida, Kazunari, Naito, Hiroyuki, Aikawa, Tomonao, Yamashita, Tetsuro, Kabata, Daijiro, and Shintani, Ayumi

Published
2019
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12. Management of odontogenic foci of infection (dental caries, periodontal disease and odontogenic infections) in the oral functional management of patients receiving cancer treatments: Guidelines based on a systematic review

Author

Kurita, Hiroshi, primary, Umeda, Masahiro, additional, Ueno, Takaaki, additional, Uzawa, Narikazu, additional, Shibuya, Yasuyuki, additional, Nakamura, Norifumi, additional, Nagatsuka, Hitoshi, additional, Hayashi, Takafumi, additional, Mizoguch, Itaru, additional, Tomihara, Kei, additional, Ikegami, Yumiko, additional, Noguchi, Kazuma, additional, Takiguchi, Yuichi, additional, Yamamoto, Nobuyuki, additional, and Sakai, Hironori, additional

Published
2023
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14. Huge glandular odontogenic cyst: Report of a case and use of CRTC1/3-MAML2fusion gene analysis for diagnosis

Author

Ohmae, Takayuki, Noguchi, Kazuma, Yamanegi, Koji, Omori, Yuji, Makihara, Yuna, Yoshikawa, Kyohei, Takaoka, Kazuki, Nakano, Yoshiro, and Kishimoto, Hiromitsu

Abstract

Glandular odontogenic cyst (GOC) is a rare odontogenic cyst with aggressive behavior. A 50-year-old Japanese man presented with pain and swelling of the mental region of the mandible. Panoramic radiography showed a clearly bordered radiolucent lesion extending from the alveolar to cortical bone of the mandible. The clinical diagnosis was an odontogenic tumor (e.g., ameloblastoma), and an incisional biopsy was performed. The histopathological diagnosis was GOC, and extirpation and tooth extraction were performed under general anesthesia. Because bone destruction is evident in patients with a huge GOC, it is important to differentiate these cysts from intraosseous mucoepidermoid carcinoma. Therefore, we analyzed the GOC for the presence of the CRTC1/3-MAML2fusion gene and found it to be negative. The patient had developed no recurrence of the GOC at the time of following.

Published
2024
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21. Whole blood transcriptome profiling identifies gene expression subnetworks and a key gene characteristic of the rare type of osteomyelitis

Author

Yahara, Hiroko, primary, Yanamoto, Souichi, additional, Takahashi, Miho, additional, Hamada, Yuji, additional, Sakamoto, Haruo, additional, Asaka, Takuya, additional, Kitagawa, Yoshimasa, additional, Moridera, Kuniyasu, additional, Noguchi, Kazuma, additional, Sugiyama, Masaya, additional, Maruoka, Yutaka, additional, and Yahara, Koji, additional

Published
2022
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22. Incidence of antiresorptive agent-related osteonecrosis of the jaw: A multicenter retrospective epidemiological study in Hyogo Prefecture, Japan

Author

Nashi, Masanori, primary, Kishimoto, Hiromitsu, additional, Kobayashi, Masaki, additional, Tachibana, Akira, additional, Suematsu, Motoo, additional, Fujiwara, Shigeyoshi, additional, Ota, Yoshiyuki, additional, Hashitani, Susumu, additional, Shibatsuji, Takeshi, additional, Nishida, Tetsuya, additional, Fujimura, Kazuma, additional, Furudoi, Shungo, additional, Ishida, Yoshiki, additional, Ishii, Shoichiro, additional, Fujita, Tsuyoshi, additional, Iwai, Soichi, additional, Shigeta, Takashi, additional, Harada, Takeshi, additional, Miyai, Daisuke, additional, Takeda, Daisuke, additional, Akashi, Masaya, additional, Noguchi, Kazuma, additional, and Takenobu, Toshihiko, additional

Published
2022
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25. Protocol for a multicentre, prospective observational study of elective neck dissection for clinically node-negative oral tongue squamous cell carcinoma (END-TC study)

Author

Yanamoto, Souichi, primary, Michi, Yasuyuki, additional, Otsuru, Mitsunobu, additional, Inomata, Toru, additional, Nakayama, Hideki, additional, Nomura, Takeshi, additional, Hasegawa, Takumi, additional, Yamamura, Yoshiko, additional, Yamada, Shin-ichi, additional, Kusukawa, Jingo, additional, Yamakawa, Nobuhiro, additional, Hasegawa, On, additional, Ueda, Michihiro, additional, Kitagawa, Yoshimasa, additional, Hiraki, Akimitsu, additional, Hasegawa, Toshihiro, additional, Ohiro, Yoichi, additional, Kobayashi, Wataru, additional, Asoda, Seiji, additional, Kobayashi, Takanori, additional, Iino, Mitsuyoshi, additional, Fukuda, Masayuki, additional, Ishibashi-Kanno, Naomi, additional, Kawaguchi, Koji, additional, Aijima, Reona, additional, Noguchi, Kazuma, additional, Okura, Masaya, additional, Tanaka, Akira, additional, Sugiura, Tsuyoshi, additional, Shintani, Yukari, additional, Yagihara, Kazuhiro, additional, Yamashiro, Masashi, additional, Ota, Yoshihide, additional, Miyazaki, Akihiro, additional, Takeshita, Akinori, additional, Kawamata, Hitoshi, additional, Hiroshi, Iwabuchi, additional, Uchida, Kenichiro, additional, Umeda, Masahiro, additional, Kurita, Hiroshi, additional, and Kirita, Tadaaki, additional

Published
2022
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27. Protocol for a multicentre, prospective observational study of elective neck dissection for clinically node-negative oral tongue squamous cell carcinoma (END-TC study)

Author

Yanamoto, Souichi, Michi, Yasuyuki, Otsuru, Mitsunobu, Inomata, Toru, Nakayama, Hideki, Nomura, Takeshi, Hasegawa, Takumi, Yamamura, Yoshiko, Yamada, Shin-ichi, Kusukawa, Jingo, Yamakawa, Nobuhiro, Hasegawa, On, Ueda, Michihiro, Kitagawa, Yoshimasa, Hiraki, Akimitsu, Hasegawa, Toshihiro, Ohiro, Yoichi, Kobayashi, Wataru, Asoda, Seiji, Kobayashi, Takanori, Iino, Mitsuyoshi, Fukuda, Masayuki, Ishibashi-Kanno, Naomi, Kawaguchi, Koji, Aijima, Reona, Noguchi, Kazuma, Okura, Masaya, Tanaka, Akira, Sugiura, Tsuyoshi, Shintani, Yukari, Yagihara, Kazuhiro, Yamashiro, Masashi, Ota, Yoshihide, Miyazaki, Akihiro, Takeshita, Akinori, Kawamata, Hitoshi, Hiroshi, Iwabuchi, Uchida, Kenichiro, Umeda, Masahiro, Kurita, Hiroshi, Kirita, Tadaaki, Yanamoto, Souichi, Michi, Yasuyuki, Otsuru, Mitsunobu, Inomata, Toru, Nakayama, Hideki, Nomura, Takeshi, Hasegawa, Takumi, Yamamura, Yoshiko, Yamada, Shin-ichi, Kusukawa, Jingo, Yamakawa, Nobuhiro, Hasegawa, On, Ueda, Michihiro, Kitagawa, Yoshimasa, Hiraki, Akimitsu, Hasegawa, Toshihiro, Ohiro, Yoichi, Kobayashi, Wataru, Asoda, Seiji, Kobayashi, Takanori, Iino, Mitsuyoshi, Fukuda, Masayuki, Ishibashi-Kanno, Naomi, Kawaguchi, Koji, Aijima, Reona, Noguchi, Kazuma, Okura, Masaya, Tanaka, Akira, Sugiura, Tsuyoshi, Shintani, Yukari, Yagihara, Kazuhiro, Yamashiro, Masashi, Ota, Yoshihide, Miyazaki, Akihiro, Takeshita, Akinori, Kawamata, Hitoshi, Hiroshi, Iwabuchi, Uchida, Kenichiro, Umeda, Masahiro, Kurita, Hiroshi, and Kirita, Tadaaki

Abstract

Introduction In early-stage oral tongue squamous cell carcinoma (OTSCC), elective neck dissection (END) is recommended when occult lymph node metastasis is suspected; however, there is no unanimous consensus on the risks and benefits of END in such cases. The management of clinically node-negative (cN0) OTSCC remains controversial. This study, therefore, aimed to evaluate the efficacy of END and its impact on the quality of life (QoL) of patients with cN0 OTSCC. Methods and analysis This is a prospective, multicentre, nonrandomised observational study. The choice of whether to perform END at the same time as resection of the primary tumour is based on institutional policy and patient preference. The primary endpoint of this study is 3-year overall survival. The secondary endpoints are 3-year disease-specific survival, 3-year relapse-free survival and the impact on patient QoL. Propensity score-matching analysis will be performed to reduce selection bias. Ethics and dissemination This study was approved by the Clinical Research Review Board of the Nagasaki University. The protocol of this study was registered at the University Hospital Medical Information Network Clinical Trials Registry. The datasets generated during the current study will be available from the corresponding author on reasonable request. The results will be disseminated internationally, through scientific and professional conferences and in peer-reviewed medical journals., BMJ open, 12 (9), art. no. e059615; 2022

Published
2022

31. Clinical T staging is superior to fluorodeoxyglucose positron emission tomography for predicting local outcomes after intra-arterial infusion chemoradiotherapy for maxillary sinus squamous cell carcinoma

Author

Doi, Hiroshi, Fujiwara, Masayuki, Kitajima, Kazuhiro, Tanooka, Masao, Terada, Tomonori, Noguchi, Kazuma, Ishikura, Reiichi, Kamikonya, Norihiko, and Yamakado, Koichiro

Subjects
paranasal sinus, intra-arterial infusion chemotherapy, concurrency, maxillary sinus, intensity-modulated radiation therapy, radiotherapy
Abstract

Concomitant intra-arterial infusion chemoradiotherapy (IA-CRT) has been used to treat locally advanced maxillary sinus squamous cell carcinoma (MSSCC) with positive outcomes. However, an optimal predictive prognostic factor for MSSCC treated with IA-CRT remains elusive. The aim of the present study was to assess the feasibility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), including volumetric parameters, to predict the prognosis of MSSCC treated with IA-CRT. Twenty-four patients with newly diagnosed MSSCC receiving FDG-PET imaging before IA-CRT treatment were analyzed in this retrospective study. All patients underwent radiotherapy with a total tumor dose of 60–66 Gy in a conventional fractionation schedule, using three-dimensional conformal radiation therapy or intensitymodulated radiation therapy. Radiotherapy was performed concurrently with concurrent intra-arterial infusion chemotherapy (cisplatin). The IA-CRT response rate was 83.33%. The 1- and 3-year survival rates were 81.30% and 64.34%, respectively. The 1- and 3-year local failure-free rates were 57.21% and 40.96%, respectively. Local failure was significantly associated with poor survival (P = 0.0152). Further, clinical T staging clearly stratified local control outcomes among patients with clinical T3 or less, T4a, and T4b (P = 0.0312). Moreover, patients with stage T4b showed a significantly poorer local control compared with T3 or less (P = 0.0103). However, FDG-PET parameters provided no significant predictive information regarding treatment outcome. To conclude, pretreatment T stage predicts local control by IA-CRT, which is associated with survival., This work was supported by a Grant-in-Aid for Young Scientists (B) Grant Number 17K16493.

Published
2018

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