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6. Opioid use disorder research and the Council for the Advancement of Nursing Science priority areas

Author

Eckardt, Patricia, Bailey, Donald, DeVon, Holli A, Dougherty, Cynthia, Ginex, Pamela, Krause-Parello, Cheryl A, Pickler, Rita H, Richmond, Therese S, Rivera, Eleanor, Roye, Carol F, and Redeker, Nancy

Subjects
Health Services and Systems, Health Sciences, Health and social care services research, 8.1 Organisation and delivery of services, Generic health relevance, Good Health and Well Being, Health Priorities, Humans, Nursing Research, Opioid-Related Disorders, Organizational Objectives, Societies, Nursing, United States, Precision health, Big data and Data analytics, Determinants of health, Global health, Opioid use disorder research, Nursing
Abstract

BackgroundChronic diseases, such as opioid use disorder (OUD) require a multifaceted scientific approach to address their evolving complexity. The Council for the Advancement of Nursing Science's (Council) four nursing science priority areas (precision health; global health, determinants of health, and big data/data analytics) were established to provide a framework to address current complex health problems.PurposeTo examine OUD research through the nursing science priority areas and evaluate the appropriateness of the priority areas as a framework for research on complex health conditions.MethodOUD was used as an exemplar to explore the relevance of the nursing science priorities for future research.FindingsResearch in the four priority areas is advancing knowledge in OUD identification, prevention, and treatment. Intersection of OUD research population focus and methodological approach was identified among the priority areas.DiscussionThe Council priorities provide a relevant framework for nurse scientists to address complex health problems like OUD.

Published
2020

10. Gut Microbiota and Symptom Expression and Severity in Neonatal Abstinence Syndrome.

Author

Sealschott, Stephanie, Pickler, Rita, Fortney, Christine, Bailey, Michael, and Loman, Brett

Subjects
*CROSS-sectional method, *REPEATED measures design, *NEONATAL abstinence syndrome, *RESEARCH funding, *T-test (Statistics), *GUT microbiome, *SCIENTIFIC observation, *STATISTICAL sampling, *SEVERITY of illness index, *DESCRIPTIVE statistics, *LONGITUDINAL method, *RESEARCH methodology, *DATA analysis software, *CONFIDENCE intervals, *SYMPTOMS
Abstract

Problem: Neonatal abstinence syndrome (NAS) affecting neonates with fetal exposure to opioids, is defined by expression and severity of symptoms. The pathophysiology behind symptoms variability is lacking. The study aims were to examine (a) differences in gut microbiota of neonates with and without NAS, (b) the relationships between gut microbiota and symptom expression and NAS severity, and (c) the changes in the neonate gut microbiota diversity during the course of NAS treatment. Methods: A cross-sectional observational design was used to examine differences in microbiota and a longitudinal, repeated measures approach was used to determine relationships between gut microbiota and NAS symptoms. Symptom data were collected using the Finnegan Neonatal Abstinence Scoring Tool and the Neonatal Pain Agitation and Sedation Scale. Stool samples were collected for microbiome analyses with 16S rRNA microbiome sequencing. Results: Differences in alpha and beta diversity between neonates with and without NAS were seen. Relative abundance results revealed 18 taxa were different in neonates with NAS compared to neonates without NAS. No differences were found in alpha or beta diversity in neonates with NAS between enrollment and hospital discharge. There was increased abundance of Escherichia-Shigella and Bacteriodes genera related to higher symptom scores. Discussion: Differences in alpha and beta diversity between neonates with and without NAS may be due to differences in birth mode and type of feeding. The findings of specific increased bacteria related to increased symptoms in the neonates with NAS may also be influenced by birth mode and type of feeding. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Using the life course health development model to address pediatric mental health disparities

Author

Smith, Laureen H., primary, Nist, Marliese D., additional, Fortney, Christine A., additional, Warren, Barbara, additional, Harrison, Tondi, additional, Gillespie, Shannon, additional, Herbell, Kayla, additional, Militello, Lisa, additional, Anderson, Cindy M., additional, Tucker, Sharon, additional, Ford, Jodi, additional, Chang, Mei‐Wei, additional, Sayre, Christine, additional, and Pickler, Rita, additional

Published
2024
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15. Families as Partners in Hospital Error and Adverse Event Surveillance

Author

Khan, Alisa, Coffey, Maitreya, Litterer, Katherine P, Baird, Jennifer D, Furtak, Stephannie L, Garcia, Briana M, Ashland, Michele A, Calaman, Sharon, Kuzma, Nicholas C, O’Toole, Jennifer K, Patel, Aarti, Rosenbluth, Glenn, Destino, Lauren A, Everhart, Jennifer L, Good, Brian P, Hepps, Jennifer H, Dalal, Anuj K, Lipsitz, Stuart R, Yoon, Catherine S, Zigmont, Katherine R, Srivastava, Rajendu, Starmer, Amy J, Sectish, Theodore C, Spector, Nancy D, West, Daniel C, Landrigan, Christopher P, Allair, Brenda K, Alminde, Claire, Alvarado-Little, Wilma, Atsatt, Marisa, Aylor, Megan E, Bale, James F, Balmer, Dorene, Barton, Kevin T, Beck, Carolyn, Bismilla, Zia, Blankenberg, Rebecca L, Chandler, Debra, Choudhary, Amanda, Christensen, Eileen, Coghlan-McDonald, Sally, Cole, F Sessions, Corless, Elizabeth, Cray, Sharon, Da Silva, Roxi, Dahale, Devesh, Dreyer, Benard, Growdon, Amanda S, Gubler, LeAnn, Guiot, Amy, Harris, Roben, Haskell, Helen, Kocolas, Irene, Kruvand, Elizabeth, Lane, Michele Marie, Langrish, Kathleen, Ledford, Christy JW, Lewis, Kheyandra, Lopreiato, Joseph O, Maloney, Christopher G, Mangan, Amanda, Markle, Peggy, Mendoza, Fernando, Micalizzi, Dale Ann, Mittal, Vineeta, Obermeyer, Maria, O’Donnell, Katherine A, Ottolini, Mary, Patel, Shilpa J, Pickler, Rita, Rogers, Jayne Elizabeth, Sanders, Lee M, Sauder, Kimberly, Shah, Samir S, Sharma, Meesha, Simpkin, Arabella, Subramony, Anupama, Thompson, E Douglas, Trueman, Laura, Trujillo, Tanner, Turmelle, Michael P, Warnick, Cindy, Welch, Chelsea, White, Andrew J, Wien, Matthew F, Winn, Ariel S, Wintch, Stephanie, Wolf, Michael, Yin, H Shonna, and Yu, Clifton E

Subjects
Clinical Trials and Supportive Activities, Clinical Research, Pediatric, Patient Safety, Good Health and Well Being, Adult, Child, Child, Hospitalized, Cohort Studies, Family, Female, Hospitals, Pediatric, Humans, Male, Medical Errors, Prospective Studies, United States, the Patient and Family Centered I-PASS Study Group, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ImportanceMedical errors and adverse events (AEs) are common among hospitalized children. While clinician reports are the foundation of operational hospital safety surveillance and a key component of multifaceted research surveillance, patient and family reports are not routinely gathered. We hypothesized that a novel family-reporting mechanism would improve incident detection.ObjectiveTo compare error and AE rates (1) gathered systematically with vs without family reporting, (2) reported by families vs clinicians, and (3) reported by families vs hospital incident reports.Design, setting, and participantsWe conducted a prospective cohort study including the parents/caregivers of 989 hospitalized patients 17 years and younger (total 3902 patient-days) and their clinicians from December 2014 to July 2015 in 4 US pediatric centers. Clinician abstractors identified potential errors and AEs by reviewing medical records, hospital incident reports, and clinician reports as well as weekly and discharge Family Safety Interviews (FSIs). Two physicians reviewed and independently categorized all incidents, rating severity and preventability (agreement, 68%-90%; κ, 0.50-0.68). Discordant categorizations were reconciled. Rates were generated using Poisson regression estimated via generalized estimating equations to account for repeated measures on the same patient.Main outcomes and measuresError and AE rates.ResultsOverall, 746 parents/caregivers consented for the study. Of these, 717 completed FSIs. Their median (interquartile range) age was 32.5 (26-40) years; 380 (53.0%) were nonwhite, 566 (78.9%) were female, 603 (84.1%) were English speaking, and 380 (53.0%) had attended college. Of 717 parents/caregivers completing FSIs, 185 (25.8%) reported a total of 255 incidents, which were classified as 132 safety concerns (51.8%), 102 nonsafety-related quality concerns (40.0%), and 21 other concerns (8.2%). These included 22 preventable AEs (8.6%), 17 nonharmful medical errors (6.7%), and 11 nonpreventable AEs (4.3%) on the study unit. In total, 179 errors and 113 AEs were identified from all sources. Family reports included 8 otherwise unidentified AEs, including 7 preventable AEs. Error rates with family reporting (45.9 per 1000 patient-days) were 1.2-fold (95% CI, 1.1-1.2) higher than rates without family reporting (39.7 per 1000 patient-days). Adverse event rates with family reporting (28.7 per 1000 patient-days) were 1.1-fold (95% CI, 1.0-1.2; P = .006) higher than rates without (26.1 per 1000 patient-days). Families and clinicians reported similar rates of errors (10.0 vs 12.8 per 1000 patient-days; relative rate, 0.8; 95% CI, .5-1.2) and AEs (8.5 vs 6.2 per 1000 patient-days; relative rate, 1.4; 95% CI, 0.8-2.2). Family-reported error rates were 5.0-fold (95% CI, 1.9-13.0) higher and AE rates 2.9-fold (95% CI, 1.2-6.7) higher than hospital incident report rates.Conclusions and relevanceFamilies provide unique information about hospital safety and should be included in hospital safety surveillance in order to facilitate better design and assessment of interventions to improve safety.

Published
2017

16. Randomized Clinical Trial of a Self-care and Communication Intervention for Parents of Adolescent/Young Adults Undergoing High-Risk Cancer Treatment: A Report From the Children’s Oncology Group

Author

Haase, Joan E., Stegenga, Kristin, Robb, Sheri L., Hooke, Mary C., Burns, Debra S., Monahan, Patrick O., Stump, Timothy E., Henley, Amanda K., Haut, Paul R., Cherven, Brooke, Roll, Lona, Langevin, Anne-Marie, Pickler, Rita H., Albritton, Karen, Hawkins, DeAnna, Osterkamp, Erin, Mitby, Pauline, Smith, Jackie, Diaz, Virginia R., Garcia-Frausto, Erica, and Moore, Margo

Published
2022
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21. The EMeRGE theory of emerging adult‐aged women's sexual and reproductive health self‐management: A grounded theory study.

Author

Schlegel, Emma C., Pickler, Rita H., Tate, Judith A., Williams, Karen Patricia, and Smith, Laureen H.

Subjects
*HEALTH services accessibility, *SELF-management (Psychology), *GROUNDED theory, *CONVERSATION, *MATHEMATICAL models, *RESEARCH methodology, *COMMUNITY colleges, *INTERVIEWING, *QUALITATIVE research, *HEALTH literacy, *HEALTH attitudes, *HEALTH behavior, *NURSING research, *RESEARCH funding, *THEORY, *DESCRIPTIVE statistics, *EMPIRICAL research, *STATISTICAL sampling, *DATA analysis software, *SEXUAL health, *WOMEN'S health, *REPRODUCTIVE health, *HEALTH promotion, *MEDICAL coding
Abstract

Aims: To explore how emerging adult‐aged women self‐manage their sexual and reproductive health and to generate a grounded theory of these self‐management processes. Design: Grounded theory methods using a constructivist approach. Methods: Between September 2019 and September 2020, 18‑ to 25‐years‐old women (n = 13) were recruited from a 4‐year university, a 2‐year community college, and neighbourhoods surrounding the institutions of higher education. Individual interviews were transcribed verbatim and qualitatively analysed using a constant comparative method and inductive coding. Results: The theory purports that core processes of sexual and reproductive health self‐management used by the women in this study included both passive and (re)active processes. These processes expanded upon and/or maintained the women's accessible sexual and reproductive health knowledge, behaviour and beliefs, defined as the sexual and reproductive health repertoire. The processes appeared to be cyclical and were often initiated by a catalysing event or catalyst and resulted in conversations with confidantes, or trusted individuals. A catalyst was either resolved or normalized by expanding or maintaining the sexual and reproductive health repertoire. Conclusion: The resulting theory, EMeRGE Theory, offers insight into the complex and cyclical processes emerging adult‐aged women use to simultaneously develop and adapt their foundational sexual and reproductive health knowledge, behaviours and beliefs. Implications for the Profession and/or Patient Care: This explication of emerging adult‐aged women's sexual and reproductive health self‐management processes can be used by nurses and nurse researchers to better address this population's unique health needs. Impact: The EMeRGE Theory provides valuable guidance for future exploratory and intervention research aimed at improving the health and well‐being of emerging adult‐aged women. Reporting Method: The authors adhered to the Consolidated Criteria for Reporting Qualitative studies (COREQ) in preparation of this publication. Patient or Public Contribution: No patient or public contribution. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Prevalence of ICU Delirium in Postoperative Pediatric Cardiac Surgery Patients

Author

Staveski, Sandra L., Pickler, Rita H., Khoury, Philip R., Ollberding, Nicholas J., Donnellan, Amy L., Mauney, Jennifer A., Lincoln, Patricia A., Baird, Jennifer D., Gilliland, Frances L., Merritt, Amber D., Presnell, Laura B., Lanese, Alexa R., Lisanti, Amy Jo, Large, Belinda J., Fineman, Lori D., Gibson, Katherine H., Mohler, Leigh A., Callow, Louise, Barnes, Sean S., Whalen, Ruby L., Grant, Mary Jo C., Sheppard, Cathy, Kline-Tilford, Andrea M., Steadman, Page W., Shafland, Heidi C., Corlett, Karen M., Kelly, Serena P., Ortman, Laura A., Peyton, Christine E., Hagstrom, Sandra K., Shields, Ashlee M., Nye, Tracy, Alvarez, T. Christine E., Justice, Lindsey B., Kidwell, Seth T., Redington, Andrew N., and Curley, Martha A. Q.

Published
2021
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31. Relationships among caregiving, stress, and self-regulation in toddlers living in poverty

Author

Bates, Randi A., Ford, Jodi L., Justice, Laura M., Pickler, Rita H., Singletary, Britt, and Dynia, Jaclyn M.

Subjects
Parents, Hydrocortisone, Child, Preschool, Humans, Infant, Mothers, Female, Poverty, Pediatrics, Article, Mother-Child Relations, United States, Self-Control
Abstract

PURPOSE: The Developmental Psychobiological Model of Experiential Canalization (DPMEC) proposes that conditions of poverty-related adversity influence child self-regulation through parental caregiving, stress hormones, and the child’s genetics. However, empirical findings investigating these relationships with prolonged stress hormones are mixed. Further, the relationships among conditions of adversity with prolonged stress hormones have seldom been investigated in toddlers living in poverty. Guided by the DPMEC, we examined the relationships among maternal caregiving, prolonged stress, and self-regulation in toddlers living in poverty in the United States, to include examining whether toddler prolonged stress mediated relations between maternal caregiving and child self-regulation. DESIGN AND METHODS: Participants were mothers and toddlers (20 to 24 months of age) living in poverty, who provided hair samples to measure four months of average cortisol concentration to estimate prolonged stress. We used observational measures to examine maternal caregiving and indirect report to measure children’s self-regulation. RESULTS: Findings did not support the role of toddler prolonged stress in mediating the relationship between maternal caregiving and toddler self-regulation. However, multiple linear regression models showed that higher levels of maternal emotionally supportive caregiving significantly predicted better toddler soothability (b = 0.90; p = .03; 95% CI [0.10, 1.69]; partial correlation = .26). CONCLUSIONS: This study adds partial support for the DPMEC to represent associations between maternal caregiving and toddler self-regulation for mothers and toddlers experiencing poverty. PRACTICE IMPLICATIONS: While these data come from an observational study, pediatric nurses may consider assessing maternal supportive caregiving upon reports of poor toddler soothability.

Published
2022

41. Integrating Research, Quality Improvement, and Medical Education for Better Handoffs and Safer Care: Disseminating, Adapting, and Implementing the I-PASS Program

Author

Landrigan, Christopher P., Spector, Nancy D., Starmer, Amy J., Sectish, Theodore C., Srivastava, Rajendu, West, Daniel C., Menon, Aravind Ajakumar, Ali, Arshia, Allair, Brenda K., Allen, April D., Almaddah, Nureddin, Alminde, Claire, Alvarado-Little, Wilma, Anson, Elizabeth, Ashland, Michele, Atsatt, Marisa, Aylor, Megan, Baird, Jennifer D., Bale, James F., Jr, Balmer, Dorene, Barber, Aisha, Barton, Kevin, Bates, Kimberly, Beck, Carolyn, Berchelmann, Kathleen, Bhan, Renuka, Bismilla, Zia, Blankenburg, Rebecca L., Boa-Hocbo, Aileen, Bordin-Wosk, Talya, Brooks, Michelle, Calaman, Sharon, Campe, Julie, Campos, Maria Lucia, Chandler, Debra, Cheung, Yvonne, Choudhary, Amanda, Christensen, Eileen, Clark, Katherine, Coffey, Maitreya, Coghlan-McDonald, Sally, Cohen, Ellen, Cole, F. Sessions, Corless, Elizabeth, Cray, Sharon, Da Silva, Roxi, Dahale, Devesh, Dalal, Anuj K., Destino, Lauren A., Doroshow, Jonathan, Dreyer, Benard, duPont, Katharine, Eagle, Steven, Edgar-Zarate, Courtney, Etzenhouser, Angie, Everhart, Jennifer L., Feraco, Angela M., Ferrer, Alexandra, Galardy, Paul, Garcia, Briana M., Gaspar-Oishi, Maria, Goldstein, Jenna, Good, Brian P., Graham, Dionne A, Growdon, Amanda S., Gubler, LeAnn, Guiot, Amy, Hanlon, Charin, Hanna-Attisha, Mona, Harris, Roben, Haskell, Helen, Hecht, Melvyn, Hehn, Rebecca S, Held, Justin, Hepps, Jennifer H., Hillier, Debra, Hiraoka, Mark, Howell, Eric, Hrach, Christine, Hughes, Helen, Huskins, Charles, Kaatz, Scott, Kanala, Vishnu, Kantrowitz, Michael, Kaplan, Peter, Kashiwagi, Deanne, Kaul, Rajat, Keohane, Carol A., Kern, Jeremy, Khan, Alisa, Khan, Nazia Naz S., Kitch, Barry, Kocolas, Irene, Kothari, Lara, Kruvand, Elizabeth, Kuzma, Nicholas, Lacy, Mary, Lane, Michele, Langrish, Kate, Ledford, Christy J.W., LeRoux, Laura, Lewis, Kheyandra, Lipsitz, Stuart, Litterer, Katherine P., Lopreiato, Joseph O., Lyons, Aimee, Mack, Avram, Mallouk, Meghan, Maloney, Christopher G., Mangan, Amanda, Mann, Keith, Markle, Peggy, Marrese, Christine, Marseille, David, Maynard, Greg, Mehta, Bijal, Mendoza, Fernando, Mercer, Alexandra N., Micalizzi, Dale, Mims, Lisa, Mittal, Vineeta, Mueller, Stephanie, Ngo, Thuy L., Nolan, Ann, Nyenpan, Christopher, Obermeyer, Maria, O'Donnell, Katherine, O'Toole, Jennifer K., Ottolini, Mary, Owolabi, Mobola, Patel, Aarti, Patel, Rajesh, Patel, Shilpa J., Perron, Catherine, Pickler, Rita, Popa, Alina, Reppert, Patrick, Riss, Robert, Roesch, Justin, Rogers, Jayne E., Rosenbluth, Glenn, Rothschild, Jeffrey M., Sanders, Lee, Sauder, Kimberly, Schnipper, Jeff, Schnock, Kumiko O, Scholtz, Amy, Seltz, Barry, Serra, Theresa, Serwint, Janet, Shah, Samir, Sharma, Meesha, Sheppard, Kathleen, Simpkin, Arabella, Sloan, Karin A, Solan, Lauren G., Southgate, Michael W, Spackman, Jaime Blank, Stevens, Scott M., Stevenson, Adam, Stevenson, Windy, Subramony, Anupama, Surkis, William, Thangarasu, Sudhagar, Thompson, E. Douglas, Toole, Cheryl, Trueman, Laura, Trujillo, Tanner, Tse, Lisa, Turmelle, Michael P., Vaniawala, Vishwas, Wagner, Tamara, Warnick, Cindy, Webster, John, Webster, Mary, Weinerman, Adina, Welch, Chelsea, White, Andrew J., Wien, Matthew F., Winn, Ariel S., Wintch, Stephanie, Yin, H. Shonna, Yoon, Catherine S., Yu, Clifton E., Zampino, Dominick, and Zigmont, Katherine R.

Published
2017
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49. Nurse Support for Children and Their Parents Returning Home From the Hospital—The H2O Study

Author

Shah, Samir, primary, Auger, Katherine, additional, Tubbs-Cooley, Heather, additional, Simmons, Jeffrey, additional, Beck, Andrew, additional, Bell, Kathleen, additional, Loechtenfeldt, Allison, additional, Sauers-Ford, Hadley, additional, Sherman, Susan, additional, Solan, Lauren, additional, Bachus, Joanne, additional, Borell, Monica, additional, Chang, Lenisa, additional, Crawford, Patricia, additional, Gold, Jennifer, additional, Heilman, Judy, additional, Khoury, Jane, additional, Kuhnell, Pierce, additional, Lawley, Karen, additional, Mangeot, Colleen, additional, Moore, Margo, additional, O'Donnell, Lynne, additional, Pfefferman, Cory, additional, Pickler, Rita, additional, Sucharew, Heidi, additional, Shah, Anita, additional, Statile, Angela, additional, Sullivan, Karen, additional, Wade-Murphy, Susan, additional, and White, Christine, additional

Published
2020
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