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13 results on '"Sanchis-Domenech C"'

6. Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study (vol 12, e0186196, 2017)

Author

Orozco D, Gil V, Redon, J, Martin-Moreno, J, Pallares-Carratala, V, Navarro-Perez, J, Valls-Roca, F, Sanchis-Domenech, C, Fernandez-Gimenez, A, Perez-Navarro, A, Bertomeu-Martinez, V, Bertomeu-Gonzalez, V, Cordero, A, de la Torre, M, Trillo, J, Carratala-Munuera, C, Pita-Fernandez, S, Uso, R, Durazo-Arvizu, R, Cooper, R, Sanz, G, Castellano, J, Ascaso, J, Carmena, R, Tellez-Plaza, M, and ESCARVAL Study Grp

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0186196.].

Published
2018

8. Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study

Author

Orozco-Beltran D, GIL V, Redon J, Martin-Moreno JM, Pallares-Carratala V, Navarro-Perez J, Valls-Roca F, Sanchis-Domenech C, Fernandez-Gimenez A, Perez-Navarro A, Bertomeu-Martinez V, Bertomeu-Gonzalez V, Cordero A, Pascual de la Torre M, Trillo JL, Carratala-Munuera C, Pita-Fernandez S, Uso R, Durazo-Arvizu R, Cooper R, Sanz G, Castellano JM, Ascaso JF, Carmena R, and Tellez-Plaza M

Abstract

Introduction The potential impact of targeting different components of an adverse lipid profile in populations with multiple cardiovascular risk factors is not completely clear. This study aims to assess the association between different components of the standard lipid profile with allcause mortality and hospitalization due to cardiovascular events in a high-risk population. Methods This prospective registry included high risk adults over 30 years old free of cardiovascular disease (2008-2012). Diagnosis of hypertension, dyslipidemia or diabetes mellitus was inclusion criterion. Lipid biomarkers were evaluated. Primary endpoints were all-cause mortality and hospital admission due to coronary heart disease or stroke. We estimated adjusted rate ratios (aRR), absolute risk differences and population attributable risk associated with adverse lipid profiles. Results 51,462 subjects were included with a mean age of 62.6 years (47.6% men). During an average follow-up of 3.2 years, 919 deaths, 1666 hospitalizations for coronary heart disease and 1510 hospitalizations for stroke were recorded. The parameters that showed an increased rate for total mortality, coronary heart disease and stroke hospitalization were, respectively, low HDL-Cholesterol: aRR 1.25, 1.29 and 1.23; high Total/HDL-Cholesterol: aRR 1.22, 1.38 and 1.25; and high Triglycerides/HDL-Cholesterol: aRR 1.21, 1.30, 1.09. The parameters that showed highest population attributable risk (%) were, respectively, low HDL-Cholesterol: 7.70, 11.42, 8.40; high Total/HDL-Cholesterol: 6.55, 12.47, 8.73; and high Triglycerides/HDL-Cholesterol: 8.94, 15.09, 6.92. Conclusions In a population with cardiovascular risk factors, HDL-cholesterol, Total/HDL-cholesterol and triglycerides/HDL-cholesterol ratios were associated with a higher population attributable risk for cardiovascular disease compared to other common biomarkers.

Published
2017

11. Evolución de la glucemia en pacientes hipertensos con síndrome metabólico, tratados con las combinaciones de trandolapril-verapamilo frente a losartán-hidroclorotiazida

Author

Sanchis Doménech, C., Iglesias Clemente, J.M., Bajo García, J., Dalfó i Baquéne, A., Domínguez Sardiña, M., Martín Rioboo, E., Nevado Loro, A., Egocheaga Cabello, M.I., Flores Becerra, I., Benítez Camps, M., Bonet Plá, A., Pepió Vilaubí, J.M., and Ureña Fernández, T.

Published
2007
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13. Correction: Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study.

Author

Orozco-Beltran D, Gil-Guillen VF, Redon J, Martin-Moreno JM, Pallares-Carratala V, Navarro-Perez J, Valls-Roca F, Sanchis-Domenech C, Fernandez-Gimenez A, Perez-Navarro A, Bertomeu-Martinez V, Bertomeu-Gonzalez V, Cordero A, de la Torre MP, Trillo JL, Carratala-Munuera C, Pita-Fernandez S, Uso R, Durazo-Arvizu R, Cooper R, Sanz G, Castellano JM, Ascaso JF, Carmena R, and Tellez-Plaza M

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0186196.].

Published
2018
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