215 results on '"Sandow, Jarrod J."'
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2. SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
3. Mapping the IMiD‐dependent cereblon interactome using BioID‐proximity labelling.
4. Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling
5. The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy
6. Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics
7. Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
8. The regulation of necroptosis by post-translational modifications
9. Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models
10. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
11. Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling.
12. Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
13. Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix
14. Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
15. Identification of novel interacting partners of the NEDD4 ubiquitin ligase in mouse testis
16. Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling
17. BAK core dimers bind lipids and can be bridged by them
18. A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
19. It takes two to tango: structure of viral kinase PK-1 reveals a new mode of kinase regulation
20. A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma
21. Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
22. Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte
23. Data from CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
24. TableS1.xlsx from CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
25. Supplementary Figures from CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
26. Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
27. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
28. CD98 defines a metabolically flexible, proinflammatory subset of low‐density neutrophils in systemic lupus erythematosus
29. Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain
30. VDAC2 enables BAX to mediate apoptosis and limit tumor development
31. Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death
32. Signalling by the βc family of cytokines
33. K‐29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis
34. Dynamic reconfiguration of pro‐apoptotic BAK on membranes
35. The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
36. Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation
37. The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
38. Proteomic analyses reveal that immune integrins are major targets for regulation by Membrane‐Associated Ring‐CH (MARCH) proteins MARCH2, 3, 4 and 9
39. CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
40. Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
41. Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death.
42. Tankyrase-mediated ADP-ribosylation is a novel regulator of TNF-induced death
43. The search for RNA-binding proteins: a technical and interdisciplinary challenge
44. How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
45. Cp1/cathepsin L is required for autolysosomal clearance in Drosophila
46. Cp1/cathepsin L is required for autolysosomal clearance in Drosophila
47. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
48. A PP2A-Integrator complex fine-tunes transcription by opposing CDK9
49. How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
50. CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
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