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Consequently, recreational ACD from epoxy resins has been reported 3 times since 2020.[[3]] Although epoxy resin-containing occupational products are well-known allergenic products, there are no regulations regarding their sale to, or use by, the general public, including minors. DISCUSSION Occupational ACD from epoxy resins is well-known.[2] However, the use of epoxy resins in recreational activities is increasing, especially with the emergence of social networks promoting such activities. Keywords: allergic contact dermatitis; case report; children; children's game; epoxy resin; non-occupational; recreational; TikTok EN allergic contact dermatitis case report children children's game epoxy resin non-occupational recreational TikTok 232 234 3 02/08/23 20230301 NES 230301 With the emergence of social networking children are engaging in new activities that expose them to contact allergens unusual for their age. [Extracted from the article]

The international Chi-PsoCov registry showed that biologics did not increase the risk of severe forms of COVID-19 in children with psoriasis. It was shown that COVID-19 may induce de novo psoriasis or flares of known psoriasis. We focused on children who developed a flare of psoriasis after infection, phenotypic aspects of the flares, and searched for associated factors. We included 149 children from February 2021 to May 2022 in 14 countries. The 11 who developed de novo psoriasis were excluded. We excluded 160 children (M / F = 1; mean age 12.4 years; plaque psoriasis 64.7%). Psoriasis worsened within 1 month of onset of COVID-19 in 26 cases (17.4%). For other children, psoriasis improved (n = 1; 0.6%) or remained same (n = 122; 81.9%). In 24 patients whose condition worsened, the phenotype was unchanged, and in 2, there were phenotype changes: plaque psoriasis to guttate or inverse psoriasis. Demographic characteristics, phenotype/severity of psoriasis or COVID-19 severity were not associated with flares. Only the use of systemic treatments at the time of infection protected against the occurrence of flares (50.0% vs. 27.3%, P = 0.049). In this study SARS-CoV-2 infection was associated with psoriasis flares in 17% of cases. In the majority of cases that worsened, the phenotype preceding the infection was preserved. These flares are not associated with the severity of psoriasis, severity of COVID-19 or other clinical parameters. Only systemic treatments seem to reduce this risk, probably by 'controlling' the flare. It is possible that a genetic susceptibility, not explored here, also explains this susceptibility to infection. [ABSTRACT FROM AUTHOR]

The article presents two case studies of focal dermal hypoplasia (FDH) mosaic or Goltz syndrome in female patients. The first patient is a 21-year-old woman with skin lesions since birth while the second patient is a 16-year-old female with healthy, non-consanguineous parents with skin lesions in a limited distribution since birth. Both patients showed a very mild phenotype and limited skin lesions suggestive the link of FDH mosaic with milder phenotype.

The article describes two cases of the rare disorder epidermolytic ichthyosis (EI) with an extensive distribution. Topics discussed include characteristics of EI, two types of segmental mosaicism of autosomal dominant skin disorders, and the importance of recognition of a mosaic form of EI for genetic counselling. The importance of being aware of KRT1 or KR10 mosaicism in an extensive distribution is also emphasized.