601 results on '"Shears, Stephen B."'
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2. Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
3. Drosophila cytokine GBP2 exerts immune responses and regulates GBP1 expression through GPCR receptor Mthl10
4. IP8: A quantitatively minor inositol pyrophosphate signaling molecule that punches above its weight
5. X-ray crystallographic analyses of 14 IPMK inhibitor complexes
6. PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.
7. A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
8. Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line
9. InsP₇ is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
10. Control of XPR1-dependent cellular phosphate efflux by InsP₈ is an exemplar for functionally-exclusive inositol pyrophosphate signaling
11. A two-way switch for inositol pyrophosphate signaling: Evolutionary history and biological significance of a unique, bifunctional kinase/phosphatase
12. Fluorination Influences the Bioisostery of Myo‐Inositol Pyrophosphate Analogs
13. Signals | The Inositol Pyrophosphate Signaling Family
14. PPIP5K
15. ITPK1 (Inositol Tetrakisphosphate 1-Kinase)
16. Use of Protein Kinase–Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors
17. Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling
18. Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress
19. KO of 5-InsP₇ kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype
20. A Short Historical Perspective of Methods in Inositol Phosphate Research
21. Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
22. The significance of the 1-kinase/1-phosphatase activities of the PPIP5K family
23. Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP7
24. Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues
25. A genome-wide dsRNA library screen for Drosophila genes that regulate the GBP/phospholipase C signaling axis that links inflammation to aging
26. Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues
27. Defining Signal Transduction by Inositol Phosphates
28. Structural and catalytic analyses of the InsP 6 kinase activities of higher plant ITPKs
29. Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery
30. A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut
31. Inositol Pyrophosphates
32. Is Intervention in Inositol Phosphate Signaling a Useful Therapeutic Option for Cystic Fibrosis?
33. Development of Novel IP6K Inhibitors for the Treatment of Obesity and Obesity-Induced Metabolic Dysfunctions
34. PPIP5K
35. ITPK1 (Inositol Tetrakisphosphate 1-Kinase)
36. Dephosphorylation of 2,3-Bisphosphoglycerate by MIPP Expands the Regulatory Capacity of the Rapoport-Luebering Glycolytic Shunt
37. Inositol Pentakis- and Hexakisphosphate Metabolism Adds Versatility to the Actions of Inositol Polyphosphates Novel Effects on Ion Channels and Protein Traffic
38. Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7† †Electronic supplementary information (ESI) available: Data deposition: atomic coordinates and structure factors have been deposited in the Protein Data Bank (PDB ID code 6N5C). See DOI: 10.1039/c9md00163h
39. The Effects of Mastoparan on the Carrot Cell Plasma Membrane Polyphosphoinositide Phospholipase C
40. Changes in Phosphatidylinositol Metabolism in Response to Hyperosmotic Stress in Daucus carota L. Cells Grown in Suspension Culture
41. Structural and catalytic analyses of the InsP6 kinase activities of higher plant ITPKs.
42. The Nucleolus Exhibits an Osmotically Regulated Gatekeeping Activity That Controls the Spatial Dynamics and Functions of Nucleolin
43. New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1
44. Metabolism and Functions of Inositol Pyrophosphates: Insights Gained from the Application of Synthetic Analogues
45. Analysis of Inositol Phosphate Metabolism by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry (CE-ESI-MS)
46. Inap
47. Interferon-Inducible RNA-Dependent Protein Kinase
48. Integrin α1 (ITGA1)
49. Interferon-Inducible eIF2α Kinase
50. Icmt (Isoprenylcysteine Carboxyl Methyltransferase)
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