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Your search keyword '"Susanne Surman-Lee"' showing total 29 results
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29 results on '"Susanne Surman-Lee"'

19. Showers

Author

James T. Walker, Susanne Surman-Lee, Paul J. McDermott, and Michael J. Weinbren

Published
2023
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27. Safe Water in Healthcare : A Practical and Clinical Guide

Author

James T. Walker, Susanne Surman-Lee, Paul J. McDermott, Michael Weinbren, James T. Walker, Susanne Surman-Lee, Paul J. McDermott, and Michael Weinbren

Subjects
Water--Pollution--Health aspects, Water--Microbiology
Abstract

Safe Water in Healthcare: A Practical and Clinical Guide enables users from different disciplines to understand all types of waterborne hazards that can pose a risk to those who might be exposed, the events which cause them to be present, what may precipitate an increase in their levels that may cause harm, and how they can be avoided or managed to reduce risk. The handbook highlights microorganisms that can cause infections, modes of transmission, the infections they cause, and risks. The book's authors draw from their extensive practical experience assisting with day-to-day problems that range from minor issues to outbreaks. The book includes case studies on the growth of biofilms and where they cause problems in water systems as well as providing practical answers to a majority of issues that arise in healthcare water and drainage systems. This is an accessible handbook that fills the gaps for those without technical knowledge for a complex but important area of infection control. It provides practical guidance for professionals who are required to design, manage and maintain water systems and help them manage associated infection outbreaks. - Discusses waterborne pathogens, their detection, identification and surveillance and describes the extent and range of recognized and emerging waterborne microorganisms as well as the diseases that occur and consequences to patients and staff - Covers hazards that can cause harm within water systems and associated equipment, the circumstances or factors that increase the risks, and the multiple modes of transmission of waterborne pathogens - Explains the importance of good design, including the type of design, management, hardware and software that can help manage and control the presence of waterborne pathogens. - Highlights who needs to be involved at each stage to ensure that patients are kept safe from waterborne pathogens, taking into account current legislation and best practices guidance

Published
2023

29. Cephalosporin resistance mechanisms in Escherichia coli isolated from raw chicken imported into the UK

Author

Hiran Dhanji, David M. Livermore, Neil Woodford, Susanne Surman Lee, Sema Durmus, Niamh Murphy, Michel Doumith, and Russell Hope

Subjects
DNA, Bacterial, Microbiology (medical), Meat, medicine.drug_class, Cephalosporin, Microbial Sensitivity Tests, Drug resistance, Biology, Cefpodoxime, medicine.disease_cause, Polymerase Chain Reaction, beta-Lactamases, Microbiology, Escherichia coli, medicine, Animals, Humans, Pharmacology (medical), Escherichia coli Infections, Antibacterial agent, Cephalosporin Resistance, Pharmacology, Escherichia coli Proteins, Sequence Analysis, DNA, biology.organism_classification, Enterobacteriaceae, United Kingdom, Anti-Bacterial Agents, Infectious Diseases, Chickens, Bacteria, medicine.drug
Abstract

We characterized mechanisms of resistance to oxyimino-cephalosporins in Escherichia coli isolated from raw chicken meat imported into the UK from South America, to ascertain whether this foodstuff contributes to the dissemination in the UK of extended-spectrum β-lactamase (ESBL)-producing E. coli belonging to the international uropathogenic ST131 clone.Sampling and collection of imported raw chicken meat was performed in accordance with regulatory guidelines by the London Port Health Authority at Tilbury. E. coli strains producing ESBLs were isolated based on growth within the zones of cefpodoxime (10 μg) discs. MICs were determined by agar dilution and interpreted using BSAC/EUCAST breakpoints. PCR was used to determine the phylogenetic groups of E. coli, to detect ESBL genes and to determine the incompatibility groups of plasmids encoding CTX-M enzymes. The molecular environments surrounding bla(CTX-M) were determined by DNA sequencing and PCR mapping.A total of 141 oxyimino-cephalosporin-resistant E. coli were isolated from 62 of 210 batches of imported raw chicken sampled. Thirty percent of these isolates produced group 2 CTX-M ESBLs, 27% produced group 8 CTX-M ESBLs, 42% produced CMY-type AmpC enzymes and 1% produced a group 2 CTX-M along with a CMY enzyme; none produced CTX-M-15 ESBL and none belonged to the ST131 clone. In contrast to human clinical ESBL E. coli,90% of isolates were susceptible to ciprofloxacin and 74% to all aminoglycosides.Raw chicken imported into the UK from South America commonly carries ESBL-producing E. coli, but is not a significant source for the ST131 clone or for the CTX-M-15 ESBL.

Published
2010
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