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Abstract Background This paper compares the most common digital signal processing methods of exon prediction in eukaryotes, and also proposes a technique for noise suppression in exon prediction. The specimen used here which has relevance in medical research, has been taken from the public genomic database - GenBank. Methods Here exon prediction has been done using the digital signal processing methods viz. binary method, EIIP (electron-ion interaction psuedopotential) method and filter methods. Under filter method two filter designs, and two approaches using these two designs have been tried. The discrete wavelet transform has been used for de-noising of the exon plots. Results Results of exon prediction based on the methods mentioned above, which give values closest to the ones found in the NCBI database are given here. The exon plot de-noised using discrete wavelet transform is also given. Conclusion Alterations to the proven methods as done by the authors, improves performance of exon prediction algorithms. Also it has been proven that the discrete wavelet transform is an effective tool for de-noising which can be used with exon prediction algorithms.

Document forgeries that involve modification of the materials used, such as ink and paper, provide evidence of any malpractices being performed. Forensic specialists use different techniques to identify and classify these samples; however, the most preferred method is to use nondestructive techniques to avoid any potential damage to the original specimen under investigation. Hyperspectral imaging has already been explored in several application domains and used as a powerful method in forensic investigations to extract information about the materials under examination. To precisely classify the material information and utilize the hyperspectral imaging technique's potential, we probed the potential of some hybrid spectral similarity measures to classify different commonly used paper samples. A comparison of these methods is quantitatively presented in this article. Hybrid spectral similarity algorithms are tested on forensic analysis of paper data. We compared the classification capabilities of various hybrid spectral similarity algorithms on hyperspectral data of 40 different paper samples. The overall accuracy (OA), kappa K̂, Z‐score of kappa (ZK̂), and the 95% confidence interval of kappa (CI(K̂)) are used for comparison. The SID‐SAM and SID‐SCA produced an overall accuracy of 88% and 87%, respectively, which is highest among the hybrid spectral similarity measures tested. [ABSTRACT FROM AUTHOR]