1. Highly Sensitive Chiral Shift Reagent Bearing Two Zinc Porphyrins
- Author
-
Toshinobu Korenaga, Nozomi Ouchi, Takashi Sakai, Tokuhiro Doi, and Tadashi Ema
- Subjects
inorganic chemicals ,Circular dichroism ,Stereochemistry ,organic chemicals ,Organic Chemistry ,chemistry.chemical_element ,Zinc ,Aziridine ,Biochemistry ,Medicinal chemistry ,Highly sensitive ,chemistry.chemical_compound ,chemistry ,Reagent ,polycyclic compounds ,heterocyclic compounds ,Physical and Theoretical Chemistry ,Enantiomer ,Chiral derivatizing agent - Abstract
A new type of chiral receptor (R,R)- or (S,S)-1b with C(2) symmetry was synthesized. An induced-fit type of binding behavior of 1b for diamines was revealed by CD spectroscopy. NMR studies demonstrated that 1b can function as a highly sensitive chiral shift reagent for the determination of the enantiomeric purity of chiral diamines, aziridine, and isoxazoline at the microgram level. [structure: see text]
- Published
- 2005