1,148 results on '"Wei, Ting-Chen"'
Search Results
2. Effect of measurement procedure errors on assessing lung fluid via remote dielectric sensing system
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Wei-Ting Chen, Yi-Ju Tsai, Hsiao-Chen Chou, Yi-Chih Pu, Jung-Yien Chien, and Chun-Ta Huang
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Heart failure ,Intra-rater reliability ,Lung fluid content ,Remote dielectric sensing system ,Standardized operating procedure ,Medicine ,Science - Abstract
Abstract The study assessed the impact of procedural errors on the remote dielectric sensing system (ReDS), a non-invasive lung fluid assessment technology, in an Asian cohort. Healthy volunteers underwent ReDS measurements following manufacturer’s instructions, with two consecutive measurements one minute apart. A subset of 20 participants had modified procedure settings. Reliability was measured using intraclass correlation coefficient (ICC). The study included 86 healthy volunteers, and all ReDS measurements fell within the recommended normal range. The intra-rater reliability of ReDS measurements was excellent, with an ICC of 0.968. Among the subset of 20 subjects, deviations in height and weight did not significantly affect ReDS values. However, deviations in chest size by ± 3 cm had a noticeable impact on ReDS measures, and incorrect station selection led to fluctuations in ReDS readings. In conclusion, the ReDS system demonstrated excellent intra-rater reliability and applicability in an Asian cohort. Procedural errors, such as chest size measurement and station selection, significantly influenced ReDS measurements. Adherence to standardized operating procedures is crucial to ensure accurate and consistent results. These findings highlight the importance of adherence to manufacturer instructions when utilizing ReDS for lung fluid assessment, thereby enhancing its reliability and clinical applicability.
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- 2024
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3. Ribotypes and antimicrobial susceptibility profiles of clinical Clostridioides difficile isolates: A multicenter, laboratory-based surveillance in Taiwan, 2019–2021
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Chin-Shiang Tsai, Po-Liang Lu, Min-Chi Lu, Tai-Chin Hsieh, Wei-Ting Chen, Jann-Tay Wang, and Wen-Chien Ko
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Clostridioides (Clostridium) difficile ,Ribotype ,Antimicrobial susceptibility ,Fidaxomicin ,Microbiology ,QR1-502 - Abstract
Background: The clinical burden of Clostridioides difficile infections (CDIs) remains substantial globally. This study aimed to investigate the ribotypes (RTs) and antimicrobial susceptibility of C. difficile isolates collected in Taiwan. Methods: C. difficile isolates were prospectively collected from four medical centers in Taiwan from 2019 to 2021. In a reference laboratory, in vitro susceptibility to clindamycin, moxifloxacin, metronidazole, vancomycin, fidaxomicin, and rifaximin were tested, and ribotyping was conducted to determine their genetic diversity. Results: A total of 568 C. difficile isolates were included. Metronidazole resistance was not observed, and the susceptibility rate of vancomycin was 99.5 %. Clindamycin showed poor activity against these isolates, with a resistance rate of 74.8 %. Fidaxomicin exhibited potent activity and 97.4 % of isolates were inhibited at 0.25 μg/mL. Rifaximin MIC90 increased from 0.015 μg/mL in 2019 to 0.03 μg/mL in 2020 and 2021. Of 40 RTs identified, two predominant RTs were RT 078/126 (78, 14 %) and 014/020 (76, 13 %). RT 017, traditional harboring truncated tcdA, accounted for 3 % (20 isolates) and there was no isolate belonging to RT 027. The proportions of RT 078 increased from 11.2 % in 2019 to 17.1 % in 2021, and the predominance of RT 078/126 was more evident in central Taiwan. Conclusions: Vancomycin, fidaxomicin, and metronidazole remain in vitro effective against clinical C. difficile isolates in Taiwan. The reservoirs and genetic relatedness of two major RTs with zoonotic potentials, RT 078/126 and 014/020, warrant further investigations.
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- 2024
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4. ATFS: A deep learning framework for angle transformation and face swapping of face de-identification.
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Chwei-Shyong Tsai, Hsien-Chu Wu, Wei-Ting Chen, and Josh Jia-Ching Ying
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- 2024
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5. A Low-Cost Pipelined Architecture Based on a Hybrid Sorting Algorithm.
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You-Rong Chen, Chien-Chia Ho, Wei-Ting Chen, and Pei-Yin Chen
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- 2024
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6. Prognostic value of arterial carbon dioxide tension during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients receiving extracorporeal resuscitation
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Pei-I Su, Min-Shan Tsai, Wei-Ting Chen, Chih-Hung Wang, Wei-Tien Chang, Matthew Huei-Ming Ma, Wen-Jone Chen, Chien-Hua Huang, and Yih-Sharng Chen
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Extracorporeal cardiopulmonary resuscitation (ECPR) ,Out-of-hospital cardiac arrest (OHCA) ,Carbon dioxide tension (PaCO2) ,Neurological outcome ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background Current guidelines on extracorporeal cardiopulmonary resuscitation (ECPR) recommend careful patient selection, but precise criteria are lacking. Arterial carbon dioxide tension (PaCO2) has prognostic value in out-of-hospital cardiac arrest (OHCA) patients but has been less studied in patients receiving ECPR. We studied the relationship between PaCO2 during cardiopulmonary resuscitation (CPR) and neurological outcomes of OHCA patients receiving ECPR and tested whether PaCO2 could help ECPR selection. Methods This single-centre retrospective study enrolled 152 OHCA patients who received ECPR between January 2012 and December 2020. Favorable neurological outcome (FO) at discharge was the primary outcome. We used multivariable logistic regression to determine the independent variables for FO and generalised additive model (GAM) to determine the relationship between PaCO2 and FO. Subgroup analyses were performed to test discriminative ability of PaCO2 in subgroups of OHCA patients. Results Multivariable logistic regression showed that PaCO2 was independently associated with FO after adjusting for other favorable resuscitation characteristics (Odds ratio [OR] 0.23, 95% Confidence Interval [CI] 0.08–0.66, p-value = 0.006). GAM showed a near-linear reverse relationship between PaCO2 and FO. PaCO2 60 min (OR, 4.66). Conclusion PaCO2 before ECMO implementation had prognostic value for neurological outcomes in OHCA patients. Patients with PaCO2
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- 2024
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7. Long-term renal function alterations in hepatitis C patients with SVRs: Impacts of therapies and mixed cryoglobulinemia
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Ming-Ling Chang, Jur-Shan Cheng, Wei-Ting Chen, Chao-Wei Hsu, Kuan-Hsing Chen, Yung-Chang Chen, and Rong-Nan Chien
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HCV ,EGFR ,Mixed cryoglobulinemia ,Interferon ,DAA ,CRP ,Infectious and parasitic diseases ,RC109-216 ,Public aspects of medicine ,RA1-1270 - Abstract
Background / Aims: Effects of anti-hepatitis C virus (HCV) therapeutic regimens and mixed cryoglobulinemia on long-term renal function of HCV-infected patients with viral clearance have not been determined. Methods/Materials: A prospective 10-year cohort study of 1212 HCV-infected patients (interferon-based therapy, n = 615; direct-acting antiviral (DAA) therapy, n = 434) was conducted. Results: At baseline, age, body mass index (BMI), hemoglobin (Hb) and uric acid (UA) levels, and fibrosis-4 score were associated with estimated glomerular filtration rates (eGFRs) in HCV-infected patients. At 24 weeks posttherapy, age, BMI, and Hb and UA levels were associated with eGFRs in patients with a sustained virological response (SVR) (n = 930). Compared with those at baseline, the eGFRs were lower in SVR patients at 24 weeks posttherapy, regardless of the therapeutic regimen. The eGFRs reverted to baseline levels in interferon-treated SVR patients up to 10 years posttherapy but remained decreased in DAA-treated SVR patients up to 4 years posttherapy. Longitudinally, repeated measures analyses with generalized estimating equations showed that the interactions between DAA-based therapy and mixed cryoglobulinemia (OR: 3.291) and Hb levels (1.778) were positively, while DAA-based therapy (0.442), age (0.956), UA levels (0.698), homeostasis model assessment-insulin resistance index (0.961) and complement 4 levels (0.9395) were negatively associated with the eGFR. Among DAA-treated SVR patients, the baseline eGFR (OR: 1.014; 95%CI OR: 1.004–1.023) and high-sensitivity C-reactive protein (HR: 1.082; 95%CI HR: 1.018–1.15) were associated with eGFR reduction at 24 weeks and 4 years posttherapy, respectively. Conclusions: Hepatic fibrosis was an HCV-related factor for renal function. Longitudinally, DAA therapy was negatively, while the interaction between DAA therapy and mixed cryoglobulinemia was positively associated with renal function in SVR patients; deteriorated renal function was recovered in interferon-treated SVR patients. Particularly in DAA-treated SVR patients, baseline renal function and systemic inflammation were associated with short- and long-term reductions in renal function, respectively.
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- 2024
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8. Diversity and distribution of small-sized planktonic ciliate communities in the East China Sea
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Wei-Ting Chen, Yun-Chi Lin, Sheng-Fang Tsai, and Kuo-Ping Chiang
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planktonic ciliate ,metabarcoding analysis ,SSU rDNA ,spatial distribution ,East China Sea (ECS) ,Science ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Ciliates are an important ecological component in the microbial food web, but few studies have been conducted on the spatial distribution of small-sized planktonic ciliate communities in the East China Sea (ECS). Investigating ciliate communities using conventional morphological approaches is particularly difficult for the small, fragile, and naked species. Therefore, we applied DNA metabarcoding analysis to explore the spatial pattern of small-sized planktonic ciliate community structure within the surface, deep chlorophyll maximum (DCM), and bottom layers. Results showed the cosmopolitan species, Leegaardiella sp., was dominant and widespread in the ECS. The relative abundance of the mixotrophic family Tontonnidae decreased in the deeper layer. We characterized water masses of the ECS using environmental variables. In nano-sized ciliate communities, non-metric multidimensional scaling (NMDS) plots revealed a correlation with temperature, salinity, density, and depth. The circulation patterns were similar to cluster analysis results, suggesting that hydrographic conditions shaped small-sized ciliate community composition.
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- 2024
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9. A 0.45‐V low‐power low‐noise amplifier using a wideband image‐rejection technology
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Jian‐Yu Hsieh and Wei‐Ting Chen
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CMOS integrated circuits ,low noise amplifiers ,low‐power electronics ,microwave detectors ,Telecommunication ,TK5101-6720 ,Electricity and magnetism ,QC501-766 - Abstract
Abstract A 0.45‐V low‐power wideband image‐rejection low‐noise amplifier (LNA) using Taiwan Semiconductor Manufacturing Company (TSMC) 0.18‐μm CMOS process has been proposed. The supply voltage, power consumption and chip area of the proposed LNA can be reduced using forward body biasing, folded cascode topology and a feedback capacitor. Moreover, a wideband gain‐enhancement‐and‐image‐rejection (WGEIR) circuit including a variable resonant LC tank and a common‐gate amplifier has been developed. The inductance of the variable resonant LC tank can enlarge the gain of the proposed LNA. The capacitance of the variable resonant LC tank can achieve the image rejection. Using the WGEIR circuit, gain enhancement and wideband image rejection can be achieved simultaneously. The variable inductors and capacitors are developed for suppressing wideband image signals and good image rejection ratio (IRR). The combination of the variable inductors and capacitors can achieve eight image‐reject frequencies under three control voltages. The proposed LNA shows the measured results including a 10‐dB power gain, a 3‐dB noise figure (NF) and a −11‐dBm input third‐order intercept point (IIP3) at 2.4 GHz, respectively. The measured IRR ranges from 18 to 23 dBc around 3.6–4.5 GHz, which is 900‐MHz image‐reject bandwidth. The measured proposed LNA using the mentioned techniques consumes 0.8‐mW power.
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- 2023
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10. DSL-FIQA: Assessing Facial Image Quality via Dual-Set Degradation Learning and Landmark-Guided Transformer.
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Wei-Ting Chen, Gurunandan Krishnan, Qiang Gao, Sy-Yen Kuo, Sizhuo Ma, and Jian Wang 0111
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- 2024
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11. RobustSAM: Segment Anything Robustly on Degraded Images.
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Wei-Ting Chen, Yu-Jiet Vong, Sy-Yen Kuo, Sizhuo Ma, and Jian Wang 0111
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- 2024
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12. Improving Point-based Crowd Counting and Localization Based on Auxiliary Point Guidance.
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I-Hsiang Chen, Wei-Ting Chen, Yu-Wei Liu, Ming-Hsuan Yang 0001, and Sy-Yen Kuo
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- 2024
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13. Evolutionary relationship between antimitochondrial antibody positivity and primary biliary cholangitis in Taiwan: a 16-year hospital cohort study
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Ming-Ling Chang, Jur-Shan Cheng, Puo-Hsien Le, Wei-Ting Chen, Hsin-Ping Ku, and Rong-Nan Chien
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Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Background: How antimitochondrial antibody (AMA)-positive patients evolve to have primary biliary cholangitis (PBC) in viral hepatitis–endemic areas is unknown. Objectives: We aimed to investigate this evolution in Taiwan. Design/methods: A 16-year medical center-based cohort study of 2,095,628 subjects was conducted in Taiwan, an Asian country endemic to viral hepatitis. AMA-positive subjects were those with positive AMA with alkaline phosphatase (ALP) ⩽1.5 times the upper limit of normal (ULN), and PBC was defined as positive AMA with ALP >1.5 × ULN. Results: AMA-positive subjects had a lower average age- and sex-adjusted prevalence than PBC patients (4.68/10 5 versus 11.61/10 5 , p = 0.0002), but their incidence was comparable (0.99/10 5 versus 1.12/10 5 , p = 0.36). The former group had a borderline significantly lower mean age (56.59 years versus 58.10 years, p = 0.06) and a lower female-to-male ratio (2.85:1 versus 5.44:1, p
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- 2024
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14. Work Status, Functional Recovery, and Quality of Life of Cardiac Arrest Survivors After Hospital Discharge
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Yi‐Wen Wu, Tai‐Yuan Chen, Chien‐Hua Huang, Yu‐Jen Chu, Wei‐Ting Chen, Kuan‐Ting Lu, Wei‐Tien Chang, Hooi‐Nee Ong, Wen‐Jone Chen, and Min‐Shan Tsai
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cardiac arrest ,functional recovery ,medical service ,quality of life ,work status ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2024
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15. Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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Wen-Cheng Chou, Wei-Ting Chen, Chun-Tse Kuo, Yao-Ming Chang, Yen-Shen Lu, Chia-Wei Li, Mien-Chie Hung, and Chen-Yang Shen
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CP: Cancer ,CP: Immunology ,Biology (General) ,QH301-705.5 - Abstract
Summary: Immune checkpoint blockade (ICB) is a promising therapy for solid tumors, but its effectiveness depends on biomarkers that are not precise. Here, we utilized genome-wide association study to investigate the association between genetic variants and tumor mutation burden to interpret ICB response. We identified 16 variants (p
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- 2024
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16. Counting Crowds in Bad Weather.
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Zhi-Kai Huang, Wei-Ting Chen, Yuan-Chun Chiang, Sy-Yen Kuo, and Ming-Hsuan Yang 0001
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- 2023
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17. NTIRE 2023 Image Shadow Removal Challenge Report.
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Florin-Alexandru Vasluianu, Tim Seizinger, Radu Timofte, Shuhao Cui, Junshi Huang, Shuman Tian, Mingyuan Fan 0002, Jiaqi Zhang, Li Zhu, Xiaoming Wei, Xiaolin Wei, Ziwei Luo, Fredrik K. Gustafsson, Zheng Zhao 0004, Jens Sjölund, Thomas B. Schön, Xiaoyi Dong, Xi Sheryl Zhang, Chenghua Li, Cong Leng, Woon-Ha Yeo, Wang-Taek Oh, Yeoreum Lee, Han-Cheol Ryu, Jinting Luo, Chengzhi Jiang, Mingyan Han, Qi Wu 0017, Wenjie Lin, Lei Yu, Xinpeng Li, Ting Jiang, Haoqiang Fan, Shuaicheng Liu, Shuning Xu, Binbin Song, Xiangyu Chen 0006, Shile Zhang, Jiantao Zhou 0001, Zhao Zhang 0001, Suiyi Zhao, Huan Zheng, Yangcheng Gao, Yanyan Wei, Bo Wang 0011, Jiahuan Ren, Yan Luo, Yuki Kondo, Riku Miyata, Fuma Yasue, Taito Naruki, Norimichi Ukita, Hua-En Chang, Hao-Hsiang Yang, Yi-Chung Chen, Yuan-Chun Chiang, Zhi-Kai Huang, Wei-Ting Chen, I-Hsiang Chen, Chia-Hsuan Hsieh, Sy-Yen Kuo, Li Xianwei, Huiyuan Fu, Chunlin Liu, Huadong Ma, Binglan Fu, Huiming He, Mengjia Wang, Wenxuan She, Yu Liu, Sabari Nathan, Priya Kansal, Zhongjian Zhang, Huabin Yang, Yan Wang, Yanru Zhang, Shruti S. Phutke, Ashutosh Kulkarni, Md Raqib Khan, Subrahmanyam Murala, Santosh Kumar Vipparthi, Heng Ye, Zixi Liu, Xingyi Yang, Songhua Liu, Yinwei Wu, Yongcheng Jing, Qianhao Yu, Naishan Zheng, Jie Huang 0017, Yuhang Long, Mingde Yao, Feng Zhao 0004, Bowen Zhao, Nan Ye, Ning Shen, Yanpeng Cao, Tong Xiong, Weiran Xia, Dingwen Li, and Shuchen Xia
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- 2023
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18. Efficient Deep Models for Real-Time 4K Image Super-Resolution. NTIRE 2023 Benchmark and Report.
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Marcos V. Conde, Eduard Zamfir, Radu Timofte, Daniel Motilla, Cen Liu, Zexin Zhang, Yunbo Peng, Yue Lin 0002, Jiaming Guo, Xueyi Zou, Yuyi Chen, Yi Liu, Jia Hao, Youliang Yan, Yuanfan Zhang, Gen Li 0008, Lei Sun 0009, Lingshun Kong, Haoran Bai, Jinshan Pan, Jiangxin Dong, Jinhui Tang 0001, Mustafa Ayazoglu, Bahri Batuhan Bilecen, Mingxi Li, Yuhang Zhang, Xianjun Fan, Yankai Sheng, Long Sun, Zibin Liu, Weiran Gou, Shaoqing Li, Ziyao Yi, Yan Xiang, Dehui Kong, Ke Xu, Ganzorig Gankhuyag, Kihwan Yoon, Jin Zhang, Gaocheng Yu, Feng Zhang, Hongbin Wang, Zhou Zhou 0015, Jiahao Chao, Hongfan Gao, Jiali Gong, Zhengfeng Yang, Zhenbing Zeng, Chengpeng Chen, Zichao Guo, Anjin Park, Yuqing Liu, Qi Jia, Hongyuan Yu, Xuanwu Yin, Dongyang Zhang, Ting Fu, Zhengxue Cheng, Shiai Zhu, Dajiang Zhou, Weichen Yu, Lin Ge, Jiahua Dong, Yajun Zou, Zhuoyuan Wu, Binnan Han, Xiaolin Zhang, Heng Zhang, Ben Shao, Shaolong Zheng, Daheng Yin, Baijun Chen, Mengyang Liu, Marian-Sergiu Nistor, Yi-Chung Chen, Zhi-Kai Huang, Yuan-Chun Chiang, Wei-Ting Chen, Hao-Hsiang Yang, Hua-En Chang, I-Hsiang Chen, Chia-Hsuan Hsieh, Sy-Yen Kuo, Tu Vo, Qingsen Yan, Yun Zhu, Jinqiu Su, Yanning Zhang, Cheng Zhang, Jiaying Luo, Youngsun Cho, Nakyung Lee, and Kunlong Zuo
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- 2023
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19. TSRFormer: Transformer Based Two-stage Refinement for Single Image Shadow Removal.
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Hua-En Chang, Chia-Hsuan Hsieh, Hao-Hsiang Yang, I-Hsiang Chen, Yi-Chung Chen, Yu-Chiang Frank Wang, Zhi-Kai Huang, Wei-Ting Chen, and Sy-Yen Kuo
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- 2023
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20. NTIRE 2023 HR NonHomogeneous Dehazing Challenge Report.
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Codruta O. Ancuti, Cosmin Ancuti, Florin-Alexandru Vasluianu, Radu Timofte, Han Zhou 0003, Wei Dong 0010, Yangyi Liu, Jun Chen 0005, Huan Liu 0014, Liangyan Li, Zijun Wu, Yubo Dong, Yuyan Li, Tian Qiu, Yu He, Yonghong Lu, Yinwei Wu, Zhenxiang Jiang, Songhua Liu, Xingyi Yang, Yongcheng Jing, Bilel Benjdira, Anas M. Ali, Anis Koubaa, Hao-Hsiang Yang, I-Hsiang Chen, Wei-Ting Chen, Zhi-Kai Huang, Yi-Chung Chen, Chia-Hsuan Hsieh, Hua-En Chang, Yuan-Chun Chiang, Sy-Yen Kuo, Yu Guo 0008, Yuan Gao 0015, Ryan Wen Liu, Yuxu Lu, Jingxiang Qu, Shengfeng He, Wenqi Ren, Trung Hoang, Haichuan Zhang, Amirsaeed Yazdani, Vishal Monga, Lehan Yang, Alex Jiahao Wu, Tiancheng Mai, Xiaofeng Cong, Xuemeng Yin, Xuefei Yin, Hazim Emad, Ahmed Abdallah, Yahya Yasser, Dalia Elshahat, Esraa Elbaz, Zhan Li 0004, Wenqing Kuang, Ziwei Luo, Fredrik K. Gustafsson, Zheng Zhao 0004, Jens Sjölund, Thomas B. Schön, Zhao Zhang 0001, Yanyan Wei, Junhu Wang, Suiyi Zhao, Huan Zheng, Jin Guo, Yangfan Sun, Tianli Liu, Dejun Hao, Kui Jiang, Anjali Sarvaiya, Kalpesh Prajapati, Ratnadeep Patra, Pragnesh Barik, Chaitanya Rathod, Kishor P. Upla, Kiran B. Raja, Raghavendra Ramachandra, and Christoph Busch 0001
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- 2023
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21. Semantic Guidance Learning for High-Resolution Non-homogeneous Dehazing.
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Hao-Hsiang Yang, I-Hsiang Chen, Chia-Hsuan Hsieh, Hua-En Chang, Yuan-Chun Chiang, Yi-Chung Chen, Zhi-Kai Huang, Wei-Ting Chen, and Sy-Yen Kuo
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- 2023
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22. NTIRE 2023 Challenge on Image Super-Resolution (×4): Methods and Results.
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Yulun Zhang, Kai Zhang 0008, Zheng Chen 0014, Yawei Li, Radu Timofte, Junpei Zhang, Kexin Zhang 0003, Rui Peng, Yanbiao Ma, Licheng Jia, Huaibo Huang, Xiaoqiang Zhou, Yuang Ai, Ran He 0001, Yajun Qiu, Qiang Zhu, Pengfei Li, Qianhui Li, Shuyuan Zhu, Dafeng Zhang, Jia Li 0044, Fan Wang 0005, Chunmiao Li, TaeHyung Kim, Jungkeong Kil, Eon Kim, Yeonseung Yu, Beomyeol Lee, Subin Lee, Seokjae Lim, Somi Chae, Heungjun Choi, Zhi-Kai Huang, YiChung Chen, Yuan-Chun Chiang, Hao-Hsiang Yang, Wei-Ting Chen, Hua-En Chang, I-Hsiang Chen, Chia-Hsuan Hsieh, Sy-Yen Kuo, Ui-Jin Choi, Marcos V. Conde, Sunder Ali Khowaja, Jiseok Yoon, Ik Hyun Lee, Garas Gendy, Nabil Sabor, Jingchao Hou, Guanghui He, Zhao Zhang 0001, Baiang Li, Huan Zheng, Suiyi Zhao, Yangcheng Gao, Yanyan Wei, Jiahuan Ren, Jiayu Wei, Yanfeng Li 0001, Jia Sun, Zhanyi Cheng, Zhiyuan Li, Xu Yao, Xinyi Wang, Danxu Li, Xuan Cui, Jun Cao, Cheng Li 0009, Jianbin Zheng, Anjali Sarvaiya, Kalpesh Prajapati, Ratnadeep Patra, Pragnesh Barik, Chaitanya Rathod, Kishor P. Upla, Kiran B. Raja, Raghavendra Ramachandra, and Christoph Busch 0001
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- 2023
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23. NTIRE 2023 Challenge on 360° Omnidirectional Image and Video Super-Resolution: Datasets, Methods and Results.
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Mingdeng Cao, Chong Mou, Fanghua Yu, Xintao Wang, Yinqiang Zheng, Jian Zhang 0018, Chao Dong, Gen Li 0008, Ying Shan, Radu Timofte, Xiaopeng Sun, Weiqi Li, Zhenyu Zhang 0005, Xuhan Sheng, Bin Chen, Haoyu Ma, Ming Cheng 0002, Shijie Zhao 0001, Wanwan Cui, Tianyu Xu, Chunyang Li, Long Bao, Heng Sun, Huaibo Huang, Xiaoqiang Zhou, Yuang Ai, Ran He 0001, Renlong Wu, Yi Yang 0001, Zhilu Zhang, Shuohao Zhang, Junyi Li, Yunjin Chen, Dongwei Ren, Wangmeng Zuo, Qian Wang, Hao-Hsiang Yang, Yi-Chung Chen, Zhi-Kai Huang, Wei-Ting Chen, Yuan-Chun Chiang, Hua-En Chang, I-Hsiang Chen, Chia-Hsuan Hsieh, Sy-Yen Kuo, Zebin Zhang, Jiaqi Zhang, Yuhui Wang, Shuhao Cui, Junshi Huang, Li Zhu, Shuman Tian, Wei Yu, and Bingchun Luo
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- 2023
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24. NTIRE 2023 Challenge on Efficient Super-Resolution: Methods and Results.
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Yawei Li, Yulun Zhang, Radu Timofte, Luc Van Gool, Lei Yu, Youwei Li, Xinpeng Li, Ting Jiang, Qi Wu 0017, Mingyan Han, Wenjie Lin, Chengzhi Jiang, Jinting Luo, Haoqiang Fan, Shuaicheng Liu, Yucong Wang, Minjie Cai, Mingxi Li, Yuhang Zhang, Xianjun Fan, Yankai Sheng, Yanyu Mao, Nihao Zhang, Qian Wang, Mingjun Zheng, Long Sun, Jinshan Pan, Jiangxin Dong, Jinhui Tang 0001, Zhongbao Yang, Yan Wang, Erlin Pan, Qixuan Cai, Xinan Dai, Magauiya Zhussip, Nikolay Kalyazin, Dmitry Vyal, Xueyi Zou, Youliang Yan, Heaseo Chung, Jin Zhang, Gaocheng Yu, Feng Zhang, Hongbin Wang, Bohao Liao, Zhibo Du, Yu-Liang Wu, Gege Shi, Long Peng, Yang Wang, Yang Cao, Zhengjun Zha, Zhi-Kai Huang, Yi-Chung Chen, Yuan-Chun Chiang, Hao-Hsiang Yang, Wei-Ting Chen, Hua-En Chang, I-Hsiang Chen, Chia-Hsuan Hsieh, Sy-Yen Kuo, Xin Liu, Jiahao Pan, Hongyuan Yu, Weichen Yu, Lin Ge, Jiahua Dong, Yajun Zou, Zhuoyuan Wu, Binnan Han, Xiaolin Zhang, Heng Zhang, Xuanwu Yin, Kunlong Zuo, Weijian Deng, Hongjie Yuan, Zengtong Lu, Mingyu Ouyang, Wenzhuo Ma, Nian Liu, Hanyou Zheng, Yuantong Zhang, Junxi Zhang, Zhenzhong Chen, Garas Gendy, Nabil Sabor, Jingchao Hou, Guanghui He, Yurui Zhu, Xi Wang, Xueyang Fu, Zheng-Jun Zha, Daheng Yin, Mengyang Liu, Baijun Chen, Ao Li 0007, Lei Luo 0003, Kangjun Jin, Ce Zhu, Xiaoming Zhang 0008, Chengxing Xie, Linze Li 0001, Haiteng Meng, Tianlin Zhang, Tianrui Li 0001, Xiaole Zhao, Zhao Zhang 0001, Baiang Li, Huan Zheng, Suiyi Zhao, Yangcheng Gao, Jiahuan Ren, Kang Hu, Jingpeng Shi, Zhijian Wu, Dingjiang Huang, Jinchen Zhu, Hui Li, Qianru Xv, Tianle Liu, Gang Wu 0010, Junpeng Jiang, Xianming Liu, Junjun Jiang, Mingjian Zhang, Shizhuang Weng, Jing Hu 0009, Chengxu Wu, Qinrui Fan, Chengming Feng, Ziwei Luo, Shu Hu 0001, Siwei Lyu, Xi Wu 0004, and Xin Wang 0001
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- 2023
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25. NTIRE 2023 Challenge on Night Photography Rendering.
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Alina Shutova, Egor I. Ershov, Georgy Perevozchikov, Ivan Ermakov, Nikola Banic, Radu Timofte, Richard Collins, Maria Efimova, Arseniy P. Terekhin, Simone Zini, Claudio Rota, Marco Buzzelli, Simone Bianco 0001, Raimondo Schettini, Chunxia Lei, Tingniao Wang, Song Wang, Shuai Liu 0009, Chaoyu Feng, Guangqi Shao, Hao Wang 0073, Xiaotao Wang, Lei Lei, Lu Xu, Chao Zhang, Yasi Wang, Jin Guo, Yangfan Sun, Tianli Liu, Hao Dejun, Furkan Kinli, Baris özcan, Furkan Kiraç, Hyerin Chung, Nakyung Lee, Sungkeun Kwak, Marcos V. Conde, Tim Seizinger, Florin-Alexandru Vasluianu, Omar Elezabi, Chia-Hsuan Hsieh, Wei-Ting Chen, Hao-Hsiang Yang, Zhi-Kai Huang, Hua-En Chang, I-Hsiang Chen, Yi-Chung Chen, and Yuan-Chun Chiang
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- 2023
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26. Effect of Online Synchronous Peer-Tutoring Writing on the Writing Performance and Attitude of Children.
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Wei-Ting Chen and Mengping Tsuei
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- 2023
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27. The iMagic E-Learning System on University Students' Achievement During the COVID-19 Pandemic: Based on Learner-Centered Instruction.
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Wei-Ting Chen and Mengping Tsuei
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- 2023
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28. Temporal and geographical prevalence of carbapenem-resistant Pseudomonas aeruginosa and the in vitro activity of ceftolozane/tazobactam and comparators in Taiwan—SMART 2012–2021
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James A. Karlowsky, Mark G. Wise, Tai-Chin Hsieh, Hung-Chi Lu, Wei-Ting Chen, Ming-Huei Cheng, Fakhar Siddiqui, Katherine Young, Mary R. Motyl, and Daniel F. Sahm
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Carbapenem-resistant ,Pseudomonas aeruginosa ,Ceftolozane/tazobactam ,Taiwan ,SMART ,Surveillance ,Microbiology ,QR1-502 - Abstract
ABSTRACT: Objectives: To determine the in vitro activities of ceftolozane/tazobactam (C/T) and comparators against Pseudomonas aeruginosa isolates cultured from hospitalised patient samples in Taiwan from 2012 to 2021 with an additional focus on the temporal and geographical prevalence of carbapenem-resistant P. aeruginosa (CRPA). Methods: P. aeruginosa isolates (n = 3013) were collected annually by clinical laboratories in northern (two medical centres), central (three medical centres), and southern Taiwan (four medical centres) as part of the SMART global surveillance program. MICs were determined by CLSI broth microdilution and interpreted using 2022 CLSI breakpoints. Molecular β-lactamase gene identification was performed on selected non-susceptible isolate subsets in 2015 and later. Results: Overall, 520 (17.3%) CRPA isolates were identified. The prevalence of CRPA increased from 11.5%–12.3% (2012–2015) to 19.4%–22.8% (2018–2021) (P ≤ 0.0001). Medical centres in northern Taiwan reported the highest percentages of CRPA. C/T, first tested in the SMART program in 2016, was highly active against all P. aeruginosa (97% susceptible), with annual susceptibility rates ranging from 94% (2017) to 99% (2020). Against CRPA, C/T inhibited >90% of isolates each year, with the exception of 2017 (79.4% susceptible). Most CRPA isolates (83%) were molecularly characterised, and only 2.1% (9/433) carried a carbapenemase (most commonly, VIM); all nine carbapenemase-positive isolates were from northern and central Taiwan. Conclusion: The prevalence of CRPA increased significantly in Taiwan from 2012 to 2021 and warrants continued monitoring. In 2021, 97% of all P. aeruginosa and 92% of CRPA in Taiwan were C/T susceptible. Routine in vitro susceptibility testing of clinical isolates of P. aeruginosa against C/T, and other newer β-lactam/β-lactamase inhibitor combinations, appears prudent.
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- 2023
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29. Programmed Intermittent Epidural Bolus Reduces Workloads in Labor Analgesia: A Single Center’s Experience
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Chia-Hung Ou and Wei-Ting Chen
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continuous epidural infusion ,epidural analgesia ,labor analgesia ,patient-controlled epidural analgesia ,programmed intermittent epidural bolus ,workload ,Medicine (General) ,R5-920 - Abstract
Background and Objectives: Labor epidural analgesia can be maintained through programmed intermittent epidural bolus (PIEB), continuous epidural infusion (CEI), or patient-controlled epidural analgesia (PCEA). Our department changed from CEI+PCEA to PIEB+PCEA as the maintenance method. The higher hourly dose setting in the current regimen brought to our concern that side effects would increase with proportional staff workloads. This study aimed to investigate the validity of our proposal that PIEB+PCEA may function as a feasible tool in reducing the amount of work in the obstetrics anesthesia units. Materials and methods: This 2-year retrospective review included parturients with vaginal deliveries under epidural analgesia. We compared the staff burden before and after the switch from CEI (6 mL/h, PCEA 6 mL lockout 15 min, group A) to PIEB (8 mL/h, PCEA 8 mL lockout 10 min, group B). The primary outcome was the difference of proportion of parturients requiring unscheduled visits between groups. Side effects and labor and neonatal outcomes were compared. Results: Of the 694 parturients analyzed, the proportion of those requiring unscheduled visits were significantly reduced in group B (20.8% vs. 27.7%, chi-square test, p = 0.033). The multivariate logistic regression showed that PIEB was associated with fewer unscheduled visits than CEI (OR = 0.53, 95% CI [0.36–0.80], p < 0.01). Group B exhibited a significantly lower incidence of asymmetric blockade, as well as motor blockade. In nulliparous subjects, obstetric anal sphincter injury occurred less frequently when PIEB+PCEA was used. Significantly more multiparous women experienced vacuum extraction delivery in group B than in group A, and they had a longer second stage of labor. Conclusions: The PIEB+PCEA protocol in our study reduced workloads in labor epidural analgesia as compared to CEI+PCEA, despite that a higher dose of analgesics was administered. Future studies are warranted to investigate the effect of manipulating the PIEB settings on the labor outcomes.
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- 2024
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30. Communities of Care Approach: Developing a Place-based Model of Care and Building Partnerships in the Communities in Central Singapore
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Wei Ting Chen, Sing Yong Lim, Shermaine How, Woan Shin Tan, and Ian Yi Onn Leong
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local communities ,care delivery ,partnership ,neighbourhood ,Medicine (General) ,R5-920 - Abstract
The population in Singapore is ageing, adding pressure to community care as the health and social needs of its residents increase. This has accelerated the pace at which Regional Health Systems adopt and deliver its population health strategies from early prevention, chronic disease management, crisis care to end-of-life care. To this end, the Central Health Integrated Care Network (ICN) began its journey to develop Communities of Care (CoCs) with other health and social care partners to meet the needs of residents in the Central Zone of Singapore. This paper describes the processes and steps taken by Central Health ICN to build partnerships with other agencies and organisations to build place-based models of care in the local neighbourhoods. The faciliating factors and the barriers faced in the implementation of CoCs were described to allow sharing of such learnings on large scale change. Strategies in overcoming some of the challenges were also presented to demonstrate the iterative processes required in building integrated place-based models of care to meet the needs of the residents in different communities.
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- 2024
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31. The influence of early adoption of nonenhanced computed tomography on management of patients with pyogenic liver abscess
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Tung‐Ying Chiang, Yung‐Ning Huang, Yu‐Chieh Weng, Xiang‐Bo Liu, Chun‐Guang Zeng, Guang‐Ming Yang, Jung‐Chieh Lee, Peng‐Xiang Liu, Chih‐Kai Yang, Pei‐Ting Cheng, Hui‐Shan Hsieh, Wei‐Ting Chen, and Yang‐Bor Lu
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computed tomography ,early diagnosis ,hospital stay ,pyogenic liver abscess ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Abstract Background and Aim A pyogenic liver abscess (PLA) is an infectious disease with high in‐hospital mortality. It has no specific symptoms and is difficult to be diagnosed early in the emergency department. Ultrasound is commonly used to detect PLA lesions of PLA, but its sensitivity can be affected by lesion size, location, and clinician experience. Therefore, early diagnosis and prompt treatment (especially abscess drainage) are crucial for better patient outcomes and should be prioritized by clinical physicians. Methods We conducted a retrospective study to compare the effect of early and late (i.e., receiving CT scanning within 48 h and >48 h after admission) adoption of nonenhanced computed tomography (CT) scanning regarding the hospitalization days and interval between admission and drainage of patients with PLA. Results This study included 76 hospitalized patients with PLA in the Department of Digestive Disease of Xiamen Chang Gung Hospital in China who underwent CT examinations from 2014 to 2021. We conducted CT scans on 56 patients within 48 h of admission and on 20 patients more than 48 h after admission. The early CT group had a significantly shorter hospitalization length compared with the late CT group (15.0 days vs. 20.5 days; P = 0.035). Besides, the median time to initiate drainage after admission was also significantly shorter in the early CT group than in the late CT group (1.0 days vs. 4.5 days; P
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- 2023
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32. A new modulation strategy on isolated battery charger with wide input and output voltage range
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Hurng‐Liahng Jou, Fu‐Zen Chen, Jinn‐Chang Wu, Chih‐Chun Chiang, Li‐Wen Su, and Wei‐Ting Chen
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AC–DC power convertors ,battery chargers ,DC–DC power convertors ,modulation ,Electronics ,TK7800-8360 - Abstract
Abstract A new wide voltage operation range isolated battery charger, which is composed of an asymmetric T‐type AC–DC power rectifier and a modified re‐configurable half bridge DC–DC power converter, is proposed in this paper. The asymmetric T‐type rectifier adopts different modulation strategies under different AC bus voltage amplitudes and different battery voltages for increasing power conversion efficiency. As the isolated DC–DC power stage, a modified re‐configurable half bridge converter applies a three‐winding transformer to achieve a wide output operation range. The proposed battery charger operates over a wide AC input voltage range and wide DC output voltage range. A 3.2 kW hardware battery charger prototype is built to adapt AC voltage between 85 and 265 V. Both constant current and constant voltage modes are implemented experimentally to charge the battery up to 6.5 A from 50 to 500 V. The experimental results prove that the proposed asymmetric T‐type rectifier adopts different modulation strategies under different AC bus voltage amplitudes and different battery voltages can increase the power conversion efficiency, the proposed DC–DC converter can output the DC voltage from 50 to 500 V and the proposed battery charger can achieve around 94% efficiency.
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- 2023
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33. Carbapenem resistance among Gram-negative isolates collected from patients in ICU and non-ICU hospital wards in Hong Kong: SMART 2017–2020
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James A. Karlowsky, Sibylle H. Lob, Tsz K. Khan, Wei-Ting Chen, Patrick C.Y. Woo, Wing Hong Seto, Margaret Ip, Stanley W.M. Leung, Queenie W.-L. Wong, Rene W.Y. Chau, C. Andrew DeRyke, Katherine Young, Mary R. Motyl, and Daniel F. Sahm
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Carbapenem resistance ,Gram-negative bacilli ,Hong Kong ,ICU ,SMART ,Surveillance ,Microbiology ,QR1-502 - Abstract
ABSTRACT: Objectives: The aim of this study was to estimate carbapenem resistance in Pseudomonas aeruginosa and Enterobacterales isolated from infected patients in intensive care unit (ICU) and non-ICU hospital wards in Hong Kong. Methods: Isolates of Pseudomonas aeruginosa (ICU, n = 35; non-ICU, n = 264) and Enterobacterales (ICU, n = 129; non-ICU, n = 1390) were collected in four Hong Kong hospitals in 2017–2020. Clinical and Laboratory Standards Institute broth microdilution minimum inhibitory concentrations (MICs) were interpreted according to Clinical and Laboratory Standards Institute 2021 M100 breakpoints. β-lactamase genes were identified in imipenem-, imipenem/relebactam-, and ceftolozane/tazobactam-nonsusceptible isolates. Results: Ceftolozane/tazobactam demonstrated potent in vitro activity against both P. aeruginosa (ICU, 88.6%; non-ICU, 98.5%) and Enterobacterales (96.1%; 97.1%). Percent susceptible values for P. aeruginosa isolates from ICU and non-ICU patients, respectively, were as follows: meropenem (ICU, 74.3%; non-ICU, 84.1%) and imipenem (68.6%; 73.1%). Only 1 of 77 isolates tested for β-lactamase genes carried a carbapenemase (VIM-2). Percent susceptible values for Enterobacterales isolates from ICU and non-ICU patients were as follows: meropenem (100%; 99.4%), ertapenem (100%; 98.0%), and imipenem (88.4%; 88.6%). A total of 62 Enterobacterales isolates were tested for β-lactamase genes. Only three isolates carried a carbapenemase gene; two (both Escherichia coli) were metallo-β-lactamase-positive (both NDM-5), and one (Klebsiella pneumoniae) was OXA-48-like-positive. Conclusions: Carbapenem-nonsusceptible isolates of P. aeruginosa were common (>15% of isolates). P. aeruginosa percent susceptible values for ceftolozane/tazobactam (97.3% susceptible overall) were ≥14% higher than those for carbapenems in both ICU and non-ICU isolates. Carbapenemases were rare among both P. aeruginosa (one isolate) and Enterobacterales (three isolates). Most Enterobacterales isolates tested from ICU and non-ICU patients in Hong Kong hospitals in 2017–2020 were susceptible to meropenem and ertapenem (≥98%); imipenem was less active (89% susceptible).
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- 2023
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34. Dispersion-engineered metasurfaces reaching broadband 90% relative diffraction efficiency
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Wei Ting Chen, Joon-Suh Park, Justin Marchioni, Sophia Millay, Kerolos M. A. Yousef, and Federico Capasso
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Science - Abstract
Abstract Dispersion results from the variation of index of refraction as well as electric field confinement in sub-wavelength structures. It usually results in efficiency decrease in metasurface components leading to troublesome scattering into unwanted directions. In this letter, by dispersion engineering, we report a set of eight nanostructures whose dispersion properties are nearly identical to each other while being capable of providing 0 to 2π full-phase coverage. Our nanostructure set enables broadband and polarization-insensitive metasurface components reaching 90% relative diffraction efficiency (normalized to the power of transmitted light) from 450 nm to 700 nm in wavelength. Relative diffraction efficiency is important at a system level – in addition to diffraction efficiency (normalized to the power of incident light) – as it considers only the transmitted optical power that can affect the signal to noise ratio. We first illustrate our design principle by a chromatic dispersion-engineered metasurface grating, then show that other metasurface components such as chromatic metalenses can also be implemented by the same set of nanostructures with significantly improved relative diffraction efficiency.
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- 2023
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35. Community of Practice of Promotoras de Salud to address health inequities during and beyond the COVID-19 pandemic
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Patricia Rodriguez Espinosa, Yessica Martinez Mulet, Wei-ting Chen, Cary Kirk, Cindy Tran, Mike Gonzalez, Lisa G. Rosas, and Promotoras Con Stanford En Acción
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COVID-19 ,health equity ,Latinx health ,community health workers ,health promotion ,capacity building ,Public aspects of medicine ,RA1-1270 - Abstract
Using principles of Community-Based Participatory Research, we describe a community of practice for community health workers and promotoras (CHW/Ps) to address COVID-19 inequities in the Latinx community. We offer a concrete example of how programs can engage CHW/Ps as full partners in the research process, and how programs can support CHW/Ps’ capacity and workforce development during implementation. We conducted four focus groups with CHW/Ps (n = 31) to understand needs and invited 15 participants to the community of practice to work on issues identified by the group. We examined impact according to number of community members reached, types of outreach activities, surveys, and online views of educational materials. Process evaluation involved two focus groups with seven organizations and a Ripple Effects Mapping session with the CHW/Ps. Our community of practice has built CHW/Ps’ capacity via 31 workshop and co-created culturally and linguistically relevant COVID-19 materials that have reached over 40,000 community members and over 3 million people online. The community of practice proved effective in supporting CHW/Ps to address COVID-19 inequities in the Latinx community. Our evaluations demonstrated benefits for community-academic partnerships, for CHW/Ps, and for the community. This model represents an innovative workforce training model to address health inequities and can be applied to other health topics.
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- 2023
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36. Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer
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Yun-Wen Lin, Hsiao-Jung Kao, Wei-Ting Chen, Cheng-Fu Kao, Jer-Yuarn Wu, Yuan-Tsong Chen, and Yi-Ching Lee
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Bone biology ,Genetics ,Medicine - Abstract
Overactive fibroblast growth factor receptor 3 (FGFR3) signaling drives pathogenesis in a variety of cancers and a spectrum of short-limbed bone dysplasias, including the most common form of human dwarfism, achondroplasia (ACH). Targeting FGFR3 activity holds great promise as a therapeutic approach for treatment of these diseases. Here, we established a receptor/adaptor translocation assay system that can specifically monitor FGFR3 activation, and we applied it to identify FGFR3 modulators from complex natural mixtures. An FGFR3-suppressing plant extract of Amaranthus viridis was identified from the screen, and 2 bioactive porphyrins, pheophorbide a (Pa) and pyropheophorbide a, were sequentially isolated from the extract and functionally characterized. Further analysis showed that Pa reduced excessive FGFR3 signaling by decreasing its half-life in FGFR3-overactivated multiple myeloma cells and chondrocytes. In an ex vivo culture system, Pa alleviated defective long bone growth in humanized ACH mice (FGFR3ACH mice). Overall, our study presents an approach to discovery and validation of plant extracts or drug candidates that target FGFR3 activation. The compounds identified by this approach may have applications as therapeutics for FGFR3-associated cancers and skeletal dysplasias.
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- 2023
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37. Value Creation Analysis: Semiconductor Intellectual Property Business Models and Dynamic Capabilities.
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Wei-Ting Chen, Mohammad Saud Khan, and Rehan Iftikhar
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- 2023
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38. Vehicle leasing credit risk assessment modeling by applying extended logistic regression.
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Yung-Chia Chang, Kuei-Hu Chang, and Wei-Ting Chen
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- 2023
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39. An Error-Resilient RISC-V Microprocessor With a Fully Integrated DC-DC Voltage Regulator for Near-Threshold Operation in 28-nm CMOS.
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Bing-Chen Wu, Wei-Ting Chen, and Tsung-Te Liu
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- 2023
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40. Missing Recovery: Single Image Reflection Removal Based on Auxiliary Prior Learning.
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Wei-Ting Chen, Kuan-Yu Chen, I-Hsiang Chen, Hao-Yu Fang, Jian-Jiun Ding, and Sy-Yen Kuo
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- 2023
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41. Similar efficacy and safety between lenvatinib versus atezolizumab plus bevacizumab as the first‐line treatment for unresectable hepatocellular carcinoma
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Chung‐Wei Su, Wei Teng, Po‐Ting Lin, Wen‐Juei Jeng, Kuei‐An Chen, Yi‐Chung Hsieh, Wei‐Ting Chen, Ming‐Mo Ho, Chia‐Hsun Hsieh, Ching‐Ting Wang, Pei‐Mei Chai, Chen‐Chun Lin, Chun‐Yen Lin, and Shi‐Ming Lin
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adverse event ,atezolizumab plus bevacizumab ,hepatocellular carcinoma ,lenvatinib ,survival ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Lenvatinib and atezolizumab plus bevacizumab(A + B) have been used for unresectable hepatocellular carcinoma (HCC) as first‐line therapy. Real‐world studies comparison of efficacy and safety in these two regimens are limited, we therefore conduct this study to investigate these issues. Methods We retrospectively reviewed patients received lenvatinib (n = 46) and A + B (n = 46) as first‐line systemic therapy for unresectable HCC in a tertiary medical center. Objective response rate (ORR), progression free survival (PFS), and overall survival (OS) were evaluated according to modified Response Evaluation Criteria in Solid Tumors (mRECIST). Inverse probability weighting (IPW) was performed for baseline clinical features balance. Results A total of 92 patients with median age of 63.8 year‐old, 78.3% male, 85.9% viral hepatitis infected, 67.4% BCLC stage C were enrolled. The median treatment and follow‐up duration were 4.7 months and 9.4 months, respectively. There was no significant difference in ORR (26.1% vs. 41.3%, p = 0.1226), PFS (5.9 vs. 5.3 months, p = 0.4066), and OS (not reached vs. not reached, p = 0.7128) between the lenvatinib and A + B groups. After IPW, the results of survival and response rate were also compared. Subgroup analysis suggested that using lenvatinib was not inferior to A + B in regards of PFS, including those with elder, Child‐Pugh class B, beyond up‐to‐seven, or portal vein invasion VP4 patients. Among the lenvatinib treated patients, multivariate analysis showed patients elder than 65‐year‐old was an independent predictor associated with shorter PFS (adjust HR: 2.085[0.914–4.753], p = 0.0213). The incidence rates of adverse events were similar between two groups (76 vs. 63%, p = 0.1740). Both of two regimens had similarly few impact on liver function by comparison of baseline, third month, and sixth month albumin‐bilirubin index and Child‐Pugh score. Conclusions The efficacy and safety of lenvatinib are similar to A + B as a first‐line systemic therapy for unresectable HCC.
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- 2023
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42. The future extreme precipitation systems of orographically locked diurnal convection: the benefits of using large-eddy simulation ensembles
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Wei-Ting Chen, Yu-Hung Chang, Chien-Ming Wu, and Huai-Yi Huang
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afternoon thunderstorm ,complex topography ,local circulation ,pseudo global warming ,storyline ,large-eddy simulations ,Meteorology. Climatology ,QC851-999 ,Environmental sciences ,GE1-350 - Abstract
The precipitation hotspot of the orographically locked convection highly depends on the interactions among physical processes governing local energetics and cloud dynamics. Accurately estimating the future change of these hotspots will require a model with sufficient spatial resolution as well as an appropriate representation of the critical physical processes. In this study, ensembles of TaiwanVVM large-eddy simulations (Δ x = 500 m) were designed to capture the summertime diurnal convection in Taiwan when local circulation dominates. The precipitation hotspots identified by long-term observations are well represented by the present-day ensemble simulations with appropriate environment variabilities. A pseudo global warming experiment is carried out to identify changes in convective structures, which results in local rainfall changes. Under the scenario of 3 K uniform warming with conserved relative humidity, the changes in the thermodynamic environment feature an overall higher convective available potential energy and a small decrease in convective inhibition (CIN), owing to the marked increase in low-level water vapor in the marine boundary layer. The results show that mean precipitation and the occurrence of extreme convective systems (ECSs) increase, with hotspots over mountains expanding toward the foothills and plains. The response in cloud dynamics leads to more short-duration, intense rainfall events. The tracking of ECSs with maximum rainfall exceeding 100 mm h ^−1 reveals more numerous short-lived ECSs (lifetime
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- 2024
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43. Impact of Postarrest Vasoactive-Inotropic Score on Acute Kidney Injury in Cardiac Arrest Survivors: A Retrospective Cohort Study
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Yu-Tzu Tien, Wen-Jone Chen, Chien-Hua Huang, Wei-Ting Chen, Hooi-Nee Ong, Tao-Ming Huang, Wei-Tien Chang, and Min-Shan Tsai
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acute kidney injury ,aki staging ,baseline kidney function ,cardiac arrest ,vasoactive inotropic score ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: Postarrest acute kidney injury (AKI) is a major health burden because it is associated with prolonged hospitalization, increased dialysis requirement, high mortality, and unfavorable neurological outcomes. Managing hemodynamic instability during the early postarrest period is critical; however, the role of quantified vasopressor dependence in AKI development in relation to illness severity remains unclear. Methods: A retrospective, observational cohort study that enrolled 411 non-traumatic adult cardiac arrest survivors without pre-arrest end-stage kidney disease between January 2017 and December 2019, grouped according to their baseline kidney function. The criteria for kidney injury were based on the Kidney Disease: Improving Global Outcomes definition and AKI staging system. The degree of vasopressor dependence within the first 24 h following return of spontaneous circulation (ROSC) was presented using the maximum vasoactive-inotropic score (VISmax). Results: Of the 411 patients, 181 (44%) had early AKI after ROSC. Patients with AKI showed an increased risk of in-hospital mortality (adjusted OR [aOR] 5.40, 95% CI 3.36–8.69, p < 0.001) and unfavorable neurological outcome (aOR 5.70, 95% CI 3.45–9.43, p < 0.001) compared to patients without AKI. The risk of adverse outcomes increased with illness severity. Patients with vasopressor support had an increased risk of early AKI. A low VISmax was associated with AKI stage 1–2 (aOR 2.51, 95% CI 1.20–5.24), whereas a high VISmax was associated with an increased risk for AKI stage 3 (aOR 2.46, 95% CI 1.28–4.75). Conclusions: Early AKI is associated with an increased risk of in-hospital mortality and unfavorable neurologic recovery in cardiac arrest survivors. Postarrest VISmax is an independent predictor of the development and severity of AKI following ROSC, regardless of baseline kidney function.
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- 2024
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44. Adaptation strategy with public space for pluvial flood risk mitigation in a densely populated city: A case study in Huwei, Taiwan
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Song-Yue Yang, Wei-Ting Chen, Cheng-Hao Lin, Ling-Fang Chang, Wen-Tsun Fang, and Bing-Chen Jhong
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Risk analysis ,Benefit-cost analysis ,Urban planning ,Retention ,Sewer ,Physical geography ,GB3-5030 ,Geology ,QE1-996.5 - Abstract
Study region: Huwei Township is located in Yunlin County, Taiwan, and its urban planning district covers an area of 5.29 km2. The land development in the district is close to saturation, and most of the public facilities have been developed. The flat terrain and the uncompleted storm sewer system lead to frequent flooding. Study focus: This study presents an adaptation strategy of adopting public space to build flood retention facilities (FRF) for pluvial flood risk mitigation in a densely populated city. This study integrates risk and benefit-cost analysis to evaluate the proposed strategy's flood mitigation effect and economic benefit. Huwei is taken as a study region to compare this strategy with traditional storm sewer (SS) construction. New hydrological insights: SS construction reduces flooded areas more than building FRF, leading to more significant flood damage. Since public space is adjacent to residential areas, FRF can directly and effectively reduce residence-related flood damage. Additionally, building FRF is less expensive than building SS. The benefit-cost ratio of building FRF is 0.45, more than twice the 0.21 of building SS. Therefore, we recommend prioritizing the construction of FRF in Huwei rather than finishing the construction of SS. This adaptation strategy can be applied to densely populated cities facing the same problems.
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- 2023
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45. NTIRE 2022 Challenge on Perceptual Image Quality Assessment.
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Jinjin Gu, Haoming Cai, Chao Dong, Jimmy S. Ren, Radu Timofte, Yuan Gong 0002, Shanshan Lao, Shuwei Shi, Jiahao Wang, Sidi Yang, Tianhe Wu, Weihao Xia, Yujiu Yang, Mingdeng Cao, Cong Heng, Lingzhi Fu, Rongyu Zhang, Yusheng Zhang, Hao Wang 0073, Hongjian Song, Jing Wang, Haotian Fan, Xiaoxia Hou, Ming Sun, Mading Li, Kai Zhao, Kun Yuan, Zishang Kong, Mingda Wu, Chuanchuan Zheng, Marcos V. Conde, Maxime Burchi, Longtao Feng, Tao Zhang 0042, Yang Li 0041, Jingwen Xu, Haiqiang Wang, Yiting Liao, Junlin Li, Kele Xu, Tao Sun, Yunsheng Xiong, Abhisek Keshari, Komal, Sadbhawana Thakur, Vinit Jakhetiya, Badri N. Subudhi, Hao-Hsiang Yang, Hua-En Chang, Zhi-Kai Huang, Wei-Ting Chen, Sy-Yen Kuo, Saikat Dutta 0002, Sourya Dipta Das, Nisarg A. Shah, and Anil Kumar Tiwari
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- 2022
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46. NTIRE 2022 Challenge on Stereo Image Super-Resolution: Methods and Results.
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Longguang Wang, Yulan Guo, Yingqian Wang 0002, Juncheng Li 0003, Shuhang Gu, Radu Timofte, Liangyu Chen 0002, Xiaojie Chu, Wenqing Yu, Kai Jin, Zeqiang Wei, Sha Guo, Angulia Yang, Xiuzhuang Zhou, Guodong Guo, Bin Dai 0001, Feiyue Peng, Huaxin Xiao, Shen Yan, Yuxiang Liu, Hanxiao Cai, Pu Cao, Yang Nie, Lu Yang 0006, Qing Song 0006, Xiaotao Hu, Jun Xu 0019, Mai Xu, Junpeng Jing, Xin Deng 0002, Qunliang Xing, Minglang Qiao, Zhenyu Guan, Wenlong Guo, Chenxu Peng, Zan Chen, Junyang Chen 0001, Hao Li 0058, Junbin Chen, Weijie Li, Zhijing Yang, Gen Li 0008, Aijin Li, Lei Sun 0009, Dafeng Zhang, Shizhuo Liu, Jiangtao Zhang, Yanyun Qu, Hao-Hsiang Yang, Zhi-Kai Huang, Wei-Ting Chen, Hua-En Chang, Sy-Yen Kuo, Qiaohui Liang, Jianxin Lin, Yijun Wang 0002, Lianying Yin, Rongju Zhang, Wei Zhao, Peng Xiao, Rongjian Xu, Zhilu Zhang, Wangmeng Zuo, Hansheng Guo, Guangwei Gao, Tieyong Zeng, Huicheng Pi, Shunli Zhang, Joohyeok Kim, HyeonA Kim, Eunpil Park, Jae-Young Sim, Jucai Zhai, Pengcheng Zeng, Yang Liu 0165, Chihao Ma, Yulin Huang, and Junying Chen
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- 2022
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47. NTIRE 2022 Challenge on Night Photography Rendering.
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Egor I. Ershov, Alexey Savchik, Denis A. Shepelev, Nikola Banic, Michael S. Brown, Radu Timofte, Karlo Koscevic, Michael Freeman, Vasily Tesalin, Dmitry Bocharov, Illya Semenkov, Marko Subasic, Sven Loncaric, Arseniy P. Terekhin, Shuai Liu 0009, Chaoyu Feng, Hao Wang 0073, Ran Zhu, Yongqiang Li, Lei Lei, Zhihao Li, Si Yi, Linghao Han, Ruiqi Wu, Xin Jin 0005, Chunle Guo, Furkan Kinli, Sami Mentes, Baris özcan, Furkan Kiraç, Simone Zini, Claudio Rota, Marco Buzzelli, Simone Bianco 0001, Raimondo Schettini, Wei Li 0002, Yipeng Ma, Tao Wang, Ruikang Xu, Fenglong Song, Wei-Ting Chen, Hao-Hsiang Yang, Zhi-Kai Huang, Hua-En Chang, Sy-Yen Kuo, Zhexin Liang, Shangchen Zhou, Ruicheng Feng, Chongyi Li, Xiangyu Chen 0006, Binbin Song, Shile Zhang, Lin Liu 0016, Zhendong Wang, Dohoon Ryu, Hyokyoung Bae, Taesung Kwon, Chaitra Desai, Nikhil Akalwadi, Amogh Joshi, Chinmayee Mandi, Sampada Malagi, Akash Uppin, Sai Sudheer Reddy, Ramesh Ashok Tabib, Ujwala Patil, and Uma Mudenagudi
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- 2022
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48. Learning Multiple Adverse Weather Removal via Two-stage Knowledge Learning and Multi-contrastive Regularization: Toward a Unified Model.
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Wei-Ting Chen, Zhi-Kai Huang, Cheng-Che Tsai, Hao-Hsiang Yang, Jian-Jiun Ding, and Sy-Yen Kuo
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- 2022
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49. NTIRE 2022 Spectral Recovery Challenge and Data Set.
- Author
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Boaz Arad, Radu Timofte, Rony Yahel, Nimrod Morag, Amir Bernat, Yuanhao Cai, Jing Lin, Zudi Lin, Haoqian Wang, Yulun Zhang, Hanspeter Pfister, Luc Van Gool, Shuai Liu 0009, Yongqiang Li, Chaoyu Feng, Lei Lei, Jiaojiao Li 0001, Songcheng Du, Chaoxiong Wu, Yihong Leng, Rui Song 0003, Mingwei Zhang, Chongxing Song, Shuyi Zhao, Zhiqiang Lang, Wei Wei 0008, Lei Zhang 0006, Renwei Dian, Tianci Shan, Anjing Guo, Chengguo Feng, Jinyang Liu, Mirko Agarla, Simone Bianco 0001, Marco Buzzelli, Luigi Celona, Raimondo Schettini, Jiang He, Yi Xiao, Jiajun Xiao, Qiangqiang Yuan, Jie Li 0022, Liangpei Zhang 0001, Taesung Kwon, Dohoon Ryu, Hyokyoung Bae, Hao-Hsiang Yang, Hua-En Chang, Zhi-Kai Huang, Wei-Ting Chen, Sy-Yen Kuo, Junyu Chen, Haiwei Li, Song Liu, Sabari Nathan, K. Uma, B. Sathya Bama 0001, and S. Mohamed Mansoor Roomi
- Published
- 2022
- Full Text
- View/download PDF
50. Single Image Reflection Removal Based on Bi-Channels Prior.
- Author
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Wei-Ting Chen, Yi-Wen Chen, Kuan-Yu Chen, Jian-Jiun Ding, and Sy-Yen Kuo
- Published
- 2022
- Full Text
- View/download PDF
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