424 results on '"Withers, Dominic J"'
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2. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
3. Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes
4. Detection of senescence using machine learning algorithms based on nuclear features
5. Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
6. COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells
7. Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study
8. Correction: Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study
9. Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH
10. β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins
11. Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice
12. Effect of the TAAR1 Partial Agonist Ralmitaront on Presynaptic Dopamine Synthesis Capacity Measured Using [ 18 F]DOPA PET in Naïve and Cocaine-Treated Mice.
13. Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine
14. Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis
15. Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity
16. Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice
17. Extrahypothalamic GABAergic nociceptin-expressing neurons regulate AgRP neuron activity to control feeding behavior
18. Cardiac glycosides are broad-spectrum senolytics
19. Genomic imprinting and its effects on postnatal growth and adult metabolism
20. Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
21. Longer Lifespan, Altered Metabolism, and Stress Resistance in Drosophila from Ablation of Cells Making Insulin-Like Ligands
22. Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome
23. Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States
24. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production
25. Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
26. Evaluation of Intraperitoneal [ 18 F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity.
27. Neuronatin regulates pancreatic [beta] cell insulin content and secretion
28. Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function
29. Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease
30. Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity
31. Phosphoinositide Signalling Pathways in Metabolic Regulation
32. Reduced insulin signaling in neurons induces sex-specific health benefits
33. Differential CpG methylation atNnatin the early establishment of beta cell heterogeneity
34. Activation of eIF4E ‐binding‐protein‐1 rescues mTORC1 ‐induced sarcopenia by expanding lysosomal degradation capacity
35. RF13 | PMON143 BRF1-Mediated Paracrine Signalling by a Subset of SOX2-Expressing Stem Cells is Required for Normal Development of the Stem Cell Compartment and Terminal Differentiation of Pituitary Committed Progenitors
36. Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity
37. Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance
38. Reduced insulin signalling in neurons induces sex-specific health benefits
39. Mammalian models of extended healthy lifespan
40. Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
41. PHYSIOLOGY: An atypical switch for metabolism and ageing
42. AGEING: Out with the old
43. Differential Effects of Laparoscopic Sleeve Gastrectomy and Laparoscopic Gastric Bypass on Appetite, Circulating Acyl-ghrelin, Peptide YY3-36 and Active GLP-1 Levels in Non-diabetic Humans
44. Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons
45. A link between FTO, ghrelin, and impaired brain food-cue responsivity
46. Longevity of insulin receptor substrate1 null mice is not associated with increased basal antioxidant protection or reduced oxidative damage
47. Long‐term p110α PI3K inactivation exerts a beneficial effect on metabolism
48. Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress
49. Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice
50. Deletion of the von Hippel--Lindau gene in pancreatic β cells impairs glucose homeostasis in mice
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