Search

As one of the methods of high-resolution 3D reconstruction, generating dense 3D point clouds from a single image has always been of high interest in the field of computer vision. In view of most methods focusing on the single feature information of the target and the large amount of sample data used, the method of a multi-stage reconstruction of dense point cloud network based on feature diversity is proposed, which is composed of the first stage of the 3D reconstruction network and the second stage of the point cloud processing network. The 3D reconstruction network can reconstruct sparse point cloud from a single image based on the fusion of 2D image target shape features and 3D point cloud pose features. The second-stage point cloud processing network extracts global and local features based on sparse point clouds, and increases the density of points by fusing global and local point features to obtain high-resolution dense point clouds. Deep learning fine-tuning technology is used to combine two networks to form an end-to-end network that can generate dense point clouds from a single image. The method in this paper is quantitatively and qualitatively analyzed through a large number of experiments on synthetic and real-world datasets. The results show that the average CD value of this method is 0.00698, and the EMD value is 2823.53. The result is better than some existing methods, and the point cloud reconstruction effect is better.

External ventricular drainage (EVD) is a common procedure in neurosurgical practice. Presently, the three methods used most often include direct EVD (dEVD), long-tunneled external ventricular drains (LTEVDs), and EVD via the Ommaya reservoir (EVDvOR). But they possess drawbacks such as limited duration of retention, vulnerability to iatrogenic secondary infections, and challenges in regulating drainage flow. This study aimed to explore the use of a modified ventriculoperitoneal shunt (mVPS)—the abdominal end of the VPS device was placed externally—as a means of temporary EVD to address the aforementioned limitations. This retrospective cohort study, included 120 cases requiring EVD. dEVD was performed for 31 cases, EVDvOR for 54 cases (including 8 cases with previously performed dEVD), and mVPS for 35 cases (including 6 cases with previously performed EVDvOR). The one-time success rate (no need for further other EVD intervention) for dEVD, EVDvOR, and mVPS were 70.97%, 88.89%, and 91.42%, dEVD vs EVDvOR (P < 0.05), dEVD vs mVPS (P < 0.05), EVDvOR vs mVPS (P > 0.05). Puncture needle displacement or detachment was observed in nearly all cases of EVDvOR, while no such complications have been observed with mVPS. Apart from this complication, the incidence of postoperative complications was 35.48%, 14.81%, and 8.5%, dEVD vs EVDvOR (P < 0.05), dEVD vs mVPS (P < 0.05), EVDvOR vs mVPS (P > 0.05). Mean postoperative retention for EVD was 14.68 ± 9.50 days, 25.96 ± 15.14 days, and 82.43 ± 64.45 days, respectively (P < 0.001). In conclusion, mVPS significantly extends the duration of EVD, which is particularly beneficial for patients requiring long-term EVD. [ABSTRACT FROM AUTHOR]

This thesis mainly studies the composite stabilizer of a series of anionic/cationic surfactant, and selects sodium dodecyl benzene sulfonate(SDBS)and tetradecyl trimethyl ammonium chloride(TTAC) as velvet pouch formation system. Adding polymer into the system under the conditions that the total concentration of surfactant is 0.02 mol/L and V(SDBS) : V(TTAC) = 7 : 3, the viscosity of the system increases, surface tension reduces, friction between the mole ules increases, binding force of the surface molecules decreases, and all of that make the system stabilization. Analysis of the particle size shows that the particle size becomes larger and distributed evenly after adding polyving akohol(PVA) of 0. 2% mass fraction into the velvet pouch system. When studying the stability of the system, velvet pouch system would be damaged by CaCl2 and MgCl2, while the stability would become better by adding PVA, and could not be easily damaged by salt. [ABSTRACT FROM AUTHOR]

Corilagin is a polyphenol has been identified anti-inflammatory properties. However, the anti-atherosclerotic effects of corilagin are not well understood. Here, we evaluated the anti-atherosclerotic effects and the underlying mechanisms of corilagin. We also verified whether corilagin can reverse atherosclerosis by regulating matrix metalloproteinase (MMP)-1, -2, and -9 in vitro and in vivo. An atherosclerosis model was established by feeding minipigs a high-fat diet combined with balloon injury, and the effects of different concentrations of corilagin on common carotid artery atherosclerosis in minipigs were monitored. Murine RAW264.7 macrophages were cultured and induced with oxidized low-density lipoprotein; fluorescence microscopy revealed the nuclear translocation of NF-κB. Furthermore, MMP-1, -2, and -9 expression in common carotid artery plaques and cellular models was detected by immunohistochemistry, western blotting, and RT-PCR. The pathological results suggested that the vascular intima of the model control group was significantly thickened, a large amount of collagen fibers was deposited, endothelial cells were damaged and detached, and plaque and foam cell formation occurred to varying degrees on the arterial wall, with lipid deposition. Corilagin treatment significantly reduced the degree of injury in the common carotid artery and decreased the number of lipid plaques and foam cells. Additionally, corilagin downregulated MMP-1, -2, and -9 expression in the common carotid artery plaques and cellular model. Moreover, corilagin significantly inhibited NF-κB nuclear translocation in vitro. Overall, corilagin exerted substantial therapeutic effects on experimental atherosclerotic minipigs via the downregulation of MMP-1, -2, and -9 expression. [ABSTRACT FROM AUTHOR]