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Simple Summary: This study aimed to examine the aging process of fibrous elements in the dermis of male volunteers over a 10-year period (47–57 years). It was observed that the aging process included visible changes in the content and organization of type I collagen fibers, resulting in changes in fibroblast morphology, and changes in type III collagen and elastic fibers. For the first time, this study presents a comparison of the dynamics of changes in morphology of the dermis in the same volunteer over a time interval of 10 years. Skin aging is a complex phenomenon influenced by multiple internal and external factors that can lead to significant changes in skin structure, particularly the degradation of key extracellular matrix (ECM) components such as collagen and elastic fibers in the dermis. In this study, we aimed to meticulously assess the morphological changes within these critical fibrous ECM elements in the dermis of the same volunteer at age 47 and 10 years later (2012 to 2022). Using advanced histological staining techniques, we examined the distribution and characteristics of ECM components, including type I collagen, type III collagen, and elastic fibers. Morphological analysis, facilitated by hematoxylin and eosin staining, allowed for an accurate assessment of fiber bundle thickness and a quantification of collagen and elastic fiber areas. In addition, we used the generalized Pareto distribution for histogram modeling to refine our statistical analyses. This research represents a pioneering effort to examine changes in ECM fiber material, specifically within the male dermis over a decade-long period. Our findings reveal substantial changes in the organization of type I collagen within the ECM, providing insight into the dynamic processes underlying skin aging. [ABSTRACT FROM AUTHOR]

This comprehensive review delineates the extensive roles of Akkermansia muciniphila in various health domains, spanning from metabolic and inflammatory diseases to neurodegenerative disorders. A. muciniphila, known for its ability to reside in the mucous layer of the intestine, plays a pivotal role in maintaining gut integrity and interacting with host metabolic processes. Its influence extends to modulating immune responses and potentially easing symptoms across several non-communicable diseases, including obesity, diabetes, inflammatory bowel disease, and cancer. Recent studies highlight its capacity to interact with the gut–brain axis, suggesting a possible impact on neuropsychiatric conditions. Despite the promising therapeutic potential of A. muciniphila highlighted in animal and preliminary human studies, challenges remain in its practical application due to stability and cultivation issues. However, the development of pasteurized forms and synthetic mediums offers new avenues for its use in clinical settings, as recognized by regulatory bodies like the European Food Safety Authority. This narrative review serves as a crucial resource for understanding the broad implications of A. muciniphila across different health conditions and its potential integration into therapeutic strategies. [ABSTRACT FROM AUTHOR]

Aesthetic medicine is a rapidly developing field of medicine. Year on year, the number of patients who undergo cosmetic ambulatory procedures increases. The COVID-19 pandemic affected all branches of healthcare including aesthetic medicine. Therefore, establishing safety protocol is of paramount importance in order to provide safe and ethical care. [ABSTRACT FROM AUTHOR]

Purpose: Surgical treatment of oral cavity neoplasms consists of the resection of tumor surrounded by a healthy tissue margin. The removal of tissues leads to breathing disturbances. Apnea episodes cause a drop in the arterial blood saturation with oxygen. This study was designed to qualitatively and quantitatively evaluate breathing disturbances and dyspnoea after resection of oral cavity structures, throat structures and muscles of the neck., Material and Methods: For this purpose, spirometry and pulsoximetry were done. Breathing disorders in sleeping patients were also examined. We enrolled 50 persons after surgery and divided them into three groups according to the type of resected structures: lateral part of the mandible; mental part of the mandible; part of the tongue., Conclusions: The following conclusions were drawn: 1) Operations in the oral cavity in spite of reconstructions result in breathing disturbances. 2) Spirometry and pulsoximetry are useful for the study of breathing disturbances. 3) Static and dynamic values of key spirometric parameters were reduced in the patients; 4) Deterioration of blood saturation during sleep in patients after operations confirms breathing disorders.

In recent years, the osteosynthesis plate has became very popular due to its quality during treatment of visceral cranium bone fractures. It is recommended to be used for stabile fusion of multi segment fractures. In the Maxillo-Facial Surgery Clinic of PMA Szczecin the presented method is applied from the mid-80-ies of the last century. Experience and obtained results permit as to state that osteosynthesis plate of visceral cranium posttraumatic fractures provides most efficient method in their treatment. It allows to establish one-time anatomical functional bone fusion, soon return to correct stomatognathic system, shortens hospitalizations time, thus securing speedy return to normal life. Analyzing the complications it was found out that in the majority of cases the decisive significance referred to: the condition of patients, time of reporting after trauma, biomechanical fusion features as wall as skill of the operator. Not always the complications were the results of the applied method.

Introduction: Surgical treatment of oral cavity neoplasms consists of the resection of tumor surrounded by a healthy tissue margin. This study is aimed at an objective, qualitative and quantitative evaluation of breathing disturbances and dyspnoea after the resection of oral cavity structures, throat structures and muscles of the neck. For the purpose of evaluating the above-mentioned disturbances an attempt was made to carry out pulse oximetry examination., Material and Methods: We have examined 50 persons after the resection of oral cavity structures, throat structures and muscles of the neck in Maxillofacial Clinic of Pomeranian Medical Academy in Szczecin. The examinations were performed by pulse oximetry set during sleep before and after operations. The patients were divided into three groups according to the type of removed structures which included: lateral part of the mandible; mental part of the mandible; part of the tongue., Results: The results of examinations obtained gave rise results as: pulse oximetry examination revealed an increased incidence of blood desaturation episodes and a decrease in minimum saturation level., Conclusions: Surgical treatment of oral cavity neoplasms leads to breathing disturbances. Apnoea episodes cause a drop in the arterial blood saturation with oxygen.

Operative treatment of developmental anomalies were presented in actual work carried out in Maxillo-Facial Clinic PMA in Szczecin. Mesiocclusion was the most frequent anomaly, followed by microgenia, joint ankylosis of tempora mandibular, next laterogenia and first and second branchial arch syndrome. The operative treatment was finished by placing and fixing the bones in new changed position. The obtained results indicated that this type of management is the best effective in correction of visceral cranium development anomalies, it assure quick maintenance of good oral hygiene as well as stabilisation and functioning jaws.