250 results on '"Zhang, Sai-Yang"'
Search Results
2. Annual review of PROTAC degraders as anticancer agents in 2022
3. Design, synthesis and biological evaluation of 1,2,3-triazole benzothiazole derivatives as tubulin polymerization inhibitors with potent anti-esophageal cancer activities
4. Discovery of novel coumarin-based derivatives as inhibitors of tubulin polymerization targeting the colchicine binding site with potent anti-gastric cancer activities
5. Design, synthesis and biological evaluation of N-benzylaryl cinnamide derivatives as tubulin polymerization inhibitors capable of promoting YAP degradation with potent anti-gastric cancer activities
6. Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine cinnamyl derivatives as inhibitors of FAK with potent anti-gastric cancer activities
7. A review of progress in o-aminobenzamide-based HDAC inhibitors with dual targeting capabilities for cancer therapy
8. Tubulin degradation: Principles, agents, and applications
9. Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities
10. Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers
11. Recent development of multi-target VEGFR-2 inhibitors for the cancer therapy
12. The dual FAK-HDAC inhibitor MY-1259 displays potent activities in gastric cancers in vitro and in vivo
13. New drug approvals for 2021: Synthesis and clinical applications
14. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway
15. Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities
16. Discovery of novel 1,2,4-triazine-chalcone hybrids as anti-gastric cancer agents via an axis of ROS-ERK-DR5 in vitro and in vivo
17. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities
18. Recent progress of oridonin and its derivatives for cancer therapy and drug resistance
19. Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers
20. Molecular diversity of phenothiazines: design and synthesis of phenothiazine–dithiocarbamate hybrids as potential cell cycle blockers
21. Discovery of 5,6-diaryl-1,2,4-triazines hybrids as potential apoptosis inducers
22. Discovery of novel coumarin-based derivatives as inhibitors of tubulin polymerization targeting the colchicine binding site with potent anti-gastric cancer activities
23. A review: hippo signaling pathway promotes tumor invasion and metastasis by regulating target gene expression
24. Progress of tubulin polymerization activity detection methods
25. Discovery of novel indole derivatives that inhibit NEDDylation and MAPK pathways against gastric cancer MGC803 cells
26. Review of NEDDylation inhibition activity detection methods
27. Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.
28. Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway
29. Discovery of novel tertiary amide derivatives as NEDDylation pathway activators to inhibit the tumor progression in vitro and in vivo
30. Engineering Multifunctional Thylakoid as an Oxygen Self-Supplying Photosensitizer for Esophageal Squamous Cell Carcinoma-Targeted Photodynamic Therapy
31. Novel tertiary sulfonamide derivatives containing benzimidazole moiety as potent anti-gastric cancer agents: Design, synthesis and SAR studies
32. Antiproliferative Evaluation In Vitro of a New Chalcone Inducing Apoptosis by ROS Generation Against MGC-803 Cells
33. Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors
34. Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues – Chlorpyrifos and Carbofuran via oxidative stress
35. Bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment exerting potent antiproliferative activity through microtubule destabilization
36. Discovery of novel arylamide derivatives containing piperazine moiety as inhibitors of tubulin polymerisation with potent liver cancer inhibitory activity.
37. Antiproliferative Evaluation of (E)-3-(3-(Allyloxy)-2-Methoxyphenyl)-1-(2,4,6-Trimethoxyphenyl)Prop-2-En-1-One as a Novel Apoptosis Inducer Against Prostate Cancer PC-3 Cells
38. Discovery of novel tranylcypromine-based derivatives as LSD1 inhibitors for gastric cancer treatment
39. A Review of the Regulatory Mechanisms of N-Myc on Cell Cycle
40. Design, synthesis and anti-tumor activity studies of novel pyrido[3, 4-d]pyrimidine derivatives
41. Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-a]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway
42. A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo
43. Synthesis and bioactivity of novel coumarin derivatives
44. Discovery of Novel Coumarin-Indole Derivatives As Tubulin Polymerization Inhibitors with Potent Anti-Gastric Cancer Activities
45. A Novel Aromatic Amide Derivative SY-65 co-Targeting Tubulin and Histone Deacetylase 1 with Potent Anticancer Activity in Vitro and in Vivo
46. WITHDRAWN: Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization
47. Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization
48. Design, Synthesis, and Anticancer Activity Studies of Novel Quinoline-Chalcone Derivatives
49. Drug Discovery Targeting Focal Adhesion Kinase (FAK) as a Promising Cancer Therapy
50. Discovery of Novel Diarylamide N-Containing Heterocyclic Derivatives as New Tubulin Polymerization Inhibitors with Anti-Cancer Activity
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