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The phononic crystals composed of soft materials have received extensive attention owing to the extraordinary behavior when undergoing large deformations, making it possible to provide tunable band gaps actively. However, the inverse designs of them mainly rely on the gradient-driven or gradient-free optimization schemes, which require sensitivity analysis or cause time-consuming, lacking intelligence and flexibility. To this end, a deep learning-based framework composed of a conditional variational autoencoder and multilayer perceptron is proposed to discover the mapping relation from the band gaps to the topology layout applied with prestress. The nonlinear superelastic neo-Hookean model is employed to describe the constitutive characteristics, based on which the band structures are obtained via the transfer matrix method accompanied with Bloch theory. The results show that the proposed data-driven approach can efficiently and rapidly generate multiple candidates applied with predicted prestress. The band gaps are in accord with each other and also consistent with the prescribed targets, verifying the accuracy and flexibility simultaneously. Furthermore, based on the generalization performance, the design space is deeply exploited to obtain desired soft structures whose stop bands are characterized by wider bandwidth, lower location, and enhanced wave attenuation performance. [ABSTRACT FROM AUTHOR]

In recent years, there has been a remarkable surge in the approval of therapeutic protein drugs, particularly recombinant glycoproteins. Drosophila melanogaster S2 cells have become an appealing platform for the production of recombinant proteins due to their simplicity and low cost in cell culture. However, a significant limitation associated with using the S2 cell expression system is its propensity to introduce simple paucimannosidic glycosylation structures, which differs from that in the mammalian expression system. It is well established that the glycosylation patterns of glycoproteins have a profound impact on the physicochemical properties, bioactivity, and immunogenicity. Therefore, understanding the mechanisms behind these glycosylation modifications and implementing measures to address it has become a subject of considerable interest. This review aims to comprehensively summarize recent advancements in glycosylation modification in S2 cells, with a particular focus on comparing the glycosylation patterns among S2, other insect cells, and mammalian cells, as well as developing strategies for altering the glycosylation patterns of recombinant glycoproteins. [ABSTRACT FROM AUTHOR]

Groundwater is the main water supply source especially in arid/semiarid regions, whose quality has been widely concerned. To clarify the spatial distribution, occurrence and the impacts of fluoride (F−) and nitrate (NO3−) in groundwater, 26 groundwater samples were collected from domestic water wells and agricultural irrigation wells in Xilinhot city, a famous tourist city on the Xilin Gol grassland of China. The integration of statistical analysis and hydrochemical diagrams and the model of health risk assessment recommended by the USEPA were carried out in the study. The analysis reveals that the groundwater is weakly alkaline, and the hydrochemical facies are mainly HCO3‐Ca·Mg and SO4·Cl‐ Na + K, which are controlled by natural processes and anthropogenic factors in the study area. Groundwater with high fluorine is chiefly located in the west of the study area, and high‐nitrate groundwater is chiefly located in the middle and southern parts of the study area. Fluoride in groundwater is predominantly derived by the weathering and dissolution of fluoride‐bearing minerals and ion exchange. The values of hazard index (HI) of 65.38% groundwater samples were greater than the recommended limit for noncarcinogenic risk (HI = 1) for children, followed by 38.46% for adult females and 30.77% for adult males. The water quality of the urban water supply should be treated. At the same time, contaminant filters and other instruments should be supplied to residents in pastoral area to reduce fluoride and nitrate concentration in drinking water, which will mitigate health risks and ensure the safety of drinking water in the study area. [ABSTRACT FROM AUTHOR]

Aiming at the problem that lightweight algorithm models are difficult to accurately detect and locate tapping surfaces and tapping key points in complex rubber forest environments, this paper proposes an improved YOLOv8n-IRP model based on the YOLOv8n-Pose. First, the receptive field attention mechanism is introduced into the backbone network to enhance the feature extraction ability of the tapping surface. Secondly, the AFPN structure is used to reduce the loss and degradation of the low-level and high-level feature information. Finally, this paper designs a dual-branch key point detection head to improve the screening ability of key point features in the tapping surface. In the detection performance comparison experiment, the YOLOv8n-IRP improves the D_mAP50 and P_mAP50 by 1.4% and 2.3%, respectively, over the original model while achieving an average detection success rate of 87% in the variable illumination test, which demonstrates enhanced robustness. In the positioning performance comparison experiment, the YOLOv8n-IRP achieves an overall better localization performance than YOLOv8n-Pose and YOLOv5n-Pose, realizing an average Euclidean distance error of less than 40 pixels. In summary, YOLOv8n-IRP shows excellent detection and positioning performance, which not only provides a new method for the key point localization of the rubber-tapping robot but also provides technical support for the unmanned rubber-tapping operation of the intelligent rubber-tapping robot. [ABSTRACT FROM AUTHOR]

In conventional gasoline automobiles, the engine powers the air conditioning system and engine noise can somewhat mask the noise and vibration of the air conditioning system. In pure electric vehicles, however, the absence of an engine makes the air conditioning system's noise more noticeable, concentrated in a limited frequency range at constant speeds. As a result, aerodynamic noise from the air conditioning system is a primary noise source in electric vehicles. Pipeline silencers are the main method for reducing this noise. The current silencer design uses plane wave acoustic theory but when cavity modal resonance occurs, the transmission loss error is relatively high. This article addresses the issue of non-planar wave cavity resonance, studying the cavity modal of a muffler using the finite element method to reveal the transmission loss under cavity mode resonance. A dual cavity expansion structure of an impedance composite muffler is proposed, with sound-absorbing materials placed in the cavity to enhance acoustic performance. The analysis of the transmission loss characteristics of the impedance composite muffler provides a theoretical basis for noise control in pure electric vehicle air conditioning systems. [ABSTRACT FROM AUTHOR]

This study presents a 3D pick-rock contact calculation method for conical picks, aiming to develop a predictive method with high accuracy and lithological tolerance for peak cutting force (PCF). The method is based on the projection profile method and D. L. Sikarskie stress distribution function. By integrating Griffith’s theory with rock damage constitutive model, the energy relationship between the rock fracturing process and crack propagation process is analyzed. Furthermore, in order to accurately correct the PCF, the energy correction function (C-Kf) is proposed to calculate the damage intensity index (Ke), which accounts for the relationship between rock brittleness and rock damage elastic–plastic energy. To validate the method, it is compared with full-scale cutting tests and three existing models, and statistical analysis confirms its high lithological tolerance and accuracy, the present model has the highest R2 of 0.90404, which is at least 12.5% higher relative to the mainstream models. Moreover, incorporating Ke into the method further enhances its predictive capability. [ABSTRACT FROM AUTHOR]

This article presents a metal matrix composite material consisting of NiTi wires embedded in nitrile butadiene rubber (NBR) that preserves NBR's inherent acoustic characteristics while enabling acoustic modification through the NiTi phase transition induced by stress and temperature. The macroscopic mechanical parameters of transversely isotropic NiTi-NBR composite materials are derived by means of a secondary bridging model that takes into account interfacial phases. On this basis, the acoustic impedance properties and absorption coefficient of composite materials were examined as a function of NiTi volume fraction using the transfer matrix method. The accuracy and effectiveness of the theoretical method were verified by comparing the calculated results with finite element simulation. The research results indicated that regulating the volume fraction of NiTi can lead to the anticipated value of the input impedance of composite materials, improving impedance matching with media like water and rubber, which offers novel insights and a theoretical foundation for the development of underwater sound-absorbing materials. [ABSTRACT FROM AUTHOR]

To address the problem that anechoic coatings frequently fall off from modern submersible hulls and are detrimental to the realization of underwater acoustic stealth, this paper focuses on the broadband sound absorbing of acoustic coverings in debonding states from fully bonded span to fully shedded conditions. Based on the non-uniform waveguide theory, subdomain splitting approach, and wave propagation theory in layered media, a global transfer matrix method (TMM) is developed for predicting the sound absorption of a composite overburden with periodic cavities in all peeling situations. Meanwhile, the corresponding acoustic-structure fully coupled finite element (FE) simulation and hydroacoustic impedance tube-based absorption experiment are sequentially performed for the lining in a semi-bonded state to comprehensively verify the accuracy and reliability of the present analytical methodology. Then, the influence laws of debonding states, material properties, and geometric parameters on the global absorption performance are investigated in depth to reveal the multiple energy dissipation mechanisms. The results show that the shedding state primarily affects the sound absorption characteristics of anechoic coatings in the low- to mid-frequency band below 7 kHz. [ABSTRACT FROM AUTHOR]

In view of the phenomenon that icy roads to road traffic accidents have severely affected,a mechanical deicing special vehicle for road deicing,which carried on the reasonable design and layout is devised.The belt drive system of mechanical deicing device is major researched,infinitesimal dynamics equation of conveyor belt is established,and the belt drive system is analyzed in theory.Through theory design and engineering design algorithm,the belt transmission torque and power is analyzed,the foundation for the further study of belt transmission is laid.By using the ANSYS and ADAMS,the stress simulation and dynamics simulation of belt drive systems are carried out,and the correctness of the preliminary design of pulley drive system is validated,the technical support of the optimum design of deicing special vehicle is provided.The study of deicing special vehicle deicing efficiency has played a key role,which with better economic benefits and promotional value.