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The bachelor thesis examines the spatial differentiation of tobacco smoking rates in the world at the national level. The thesis is divided into theoretical and practical parts. It aims to analyse tobacco use rates in different countries of the world and to produce more general outcomes at the macro-regional level based on the results obtained. The sociopathological phenomenon under study is analyzed using nine socio-economic indicators, which are divided into three groups - economic, social and other. Using correlation analysis of the selected determinants, the dependence of each indicator with the proportion of adult smokers is observed. With the help of the created map outputs, some spatial differences, certain specifics and regularities of the observed phenomenon are clarified, which in the conclusion of the work confirm or refute the established hypotheses.