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Methods of Animal Experimentation, Volume III, compiles methods of animal experimentation in a variety of fields so that the researcher might have a reference that would allow him to incorporate other techniques in his research studies. The methods described represent only the most efficient ways known to date for using animals to gain research information. They are not, however,''standard methods''for research in which each experiment seeks or confirms new information by another means. The largest portion of this volume is devoted to behavioral science because of the growing importance of this field in two respects. First, it is an important consideration in all experiments in which animals are used repeatedly. Second, the use of higher animals in comparative behavioral research offers much toward the solution of disease problems of man related to behavior and perhaps even clues to his social interactions. A chapter by an author with extensive experiences with dolphins helps us judge how this animal may be used, and warns of the many problems incurred in research using any of the marine mammals. Other chapters cover dental research on animals, fetal surgery and physiological measurements in very young animals, and microsurgery.

Methods of Animal Experimentation, Volume II, provides information on the most common methods for using animals as tools in the search for new biological knowledge. The techniques described will facilitate the most efficient use of research animals and provide guidelines for their utmost comfort and welfare. The text is arranged according to specific research methods rather than to organ system or disease category. This approach gives the reader a broad view of the techniques involved in specific fields and describes the range of usefulness of these techniques. The chapters in the present volume deal with special techniques which have been demonstrated to be distinct, useful methods for using laboratory animals as a basic biomedical research tool. The descriptions of both fundamental and well-developed techniques of animal experimentation in various research fields should be useful to graduate students and experienced scientists who must consider variations in research approaches. The book is a source of information for the scientist administrator who is frequently confronted with different proposed approaches to biological research projects utilizing animals.

Methods of Animal Experimentation, Volume I, provides information on the most common methods for using animals as tools in the search for new biological knowledge. The techniques described will facilitate the most efficient use of research animals and provide guidelines for their utmost comfort and welfare. The text is arranged according to specific research methods rather than to organ system or disease category. This approach gives the reader a broad view of the techniques involved in specific fields and describes the range of usefulness of these techniques. The first five chapters of the present volume describe basic information, methods, and principles involved in managing animals for experimental procedures. The remaining chapters deal with special techniques which have been demonstrated to be distinct, useful methods for using laboratory animals as a basic biomedical research tool. The descriptions of both fundamental and well-developed techniques of animal experimentation in various research fields should be useful to graduate students and experienced scientists who must consider variations in research approaches. The book is a source of information for the scientist administrator who is frequently confronted with different proposed approaches to biological research projects utilizing animals.

Methods of Animal Experimentation, Volume IV focuses on research problems related to animal experimentation, including aging, nutrition, and environmental studies. It summarizes therapeutic implications of animal experimentation methods to human application. Chapter 1 presents an introduction to inhalation chambers including discussions of the types of inhalation tests, inhalation equipment and technology, methods of generation and measurement of contaminants, and some of the specialized techniques available for the pulmonary exposure of animals. Chapter 2 provides practical information about methods and the auditory abilities of animals. Chapter 3 outlines some basic properties of the vertebrate olfactory systems and summarizes selected experimental methods and findings in olfactory research. The concluding chapter describes the use of vertebrate laboratory animals in gustatory research, including some procedures unique to taste research. Research scientists, medical researchers, and olfaction and gustatory experts will find this book invaluable.