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Forty cases of lichen amyloidosis were found in 2 medical units in a Singapore general medical hospital over a 3-year period The majority of the patients were middle-age Chinese females with a long standing history (over 20 years) of the disease. Pruritus was significantly absent in 37.5%. The common cutaneous lesions were papules (62.5%,) and plaques (22.5% found mostly on the shins and thighs (90%). A number of precipitating factors and associated skin diseases were noted, but their relationship to lichen amyloidosis is obscure. Treatment with intralesional and topical steroids is discussed. [ABSTRACT FROM AUTHOR]