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The article presents an ecological analysis of urban mortality rates in the U.S. According to the authors much of the work taking account of the health factors has been done in a comparative perspective with the general conclusion being that improved health conditions and services and not pure economic factors have been the main influence in lowering mortality in the developing nations. The purpose of this paper is to examine the ecological correlates of neighborhood mortality levels in a large urban center. The focus is upon the identification of the relative contribution of demographic, environmental, and social organizational variables to the explanation of differences in urban subarea death rates. The authors take as their starting point the works of those social scientists who have clearly demonstrated the relationship of ecological phenomena to differential urban mortality. Past studies have shown the importance of a large number of specific variables in explaining differential aggregate community mortality levels. These specific variables may be grouped into three gross categories, such as demographic, environmental, and social organizational.