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Platelet adhesion to glass, polyethylene, polyvinyl chloride, and Cuprophane has been studied by means of a method specific for quantitation of adhesion. Platelets adhered in larger numbers to polyethylene and polyvinyl chloride than to Cuprophane or glass regardless of the anticoagulant used. In citrated plasma, fewer platelets adhered to glass than to Cuprophane, although adhesion to glass and Cuprophane was nearly the same when EDTA or heparin was used as anticoagulant. The number of adherent platelets decreased appreciably from values obtained with citrated platelet-rich plasma, when EDTA or heparin was used as anticoagulant. Adhesiveness of normal platelets increased with age. A number of different pharmacologic and other agents were found to inhibit platelet adhesion to artificial surfaces. Acetylsalicylic acid and glucosamine were less effective inhibitors than sulfinpyrazone, imipramine, desipramine, amitriptyline, chlorpromazine, or PCMB. Penicillin did not inhibit adhesion. Donors deficient in factors VIII, XI, or XII or donors with von Willebrand’s disease showed normal platelet adhesiveness. Adhesiveness was markedly low in tests with blood from afibrinogenemic or thrombasthenic patients. Decreased adhesiveness of afibrinogenemic platelets could be corrected by addition of fibrinogen.

THERE has been a gradual broadening of our concept of the role of the anonymous mycobacteria (Table 11) in human disease. Formerly considered to be nonpathogenic saprophytes, they are now firmly established as causes of pulmonary disease and of cervical adenitis in children.2 In addition, they have occasionally been obtained in culture from such extrapulmonary foci as the genitourinary tract, bones, and joints.3 Widespread, disseminated, anonymous, mycobacterial infections are rare, however, and we have been able to find only 16 such cases in the English literature.4-14 This report presents two additional patients with disseminated disease due to photochromogenic Mycobacterium kansasii which appeared concomitantly with unusual hematologic disorders. Although the coexistence of disseminated M tuberculosis with blood dyscrasias has been noted frequently, no comment has thus far been made concerning the relationship of disorders of the blood and anonymous mycobacteria. It is our purpose to review briefly

The city planner, in playing his role, engages in a social process which can be analyzed in terms of a planning role, a client role, and a community decision network - all interacting around a public agenda. In the conceptual framework presented here, the planner is viewed as having a primary relationship with his client group, whom he must first motivate. Then, together, the planner-client team must relate to the larger community network, which they attempt to move. Both sets of relationships are affected by role postures, situational factors, and environmental conditions. This analysis suggests that traditional notions of the planner's role are too narrowly focused on substantive methodologies which imply highly simplistic assumptions about the social setting for planning.

This paper sets forth a conceptual framework for better understanding the relationships between the planning process and community decision-making. From an initial assumption concerning the nature of the decision-making process, the paper suggests four sets of independent variables that affect decision outcomes: (1) process roles (including the dimensions of specialization and skill); (2) the decision field (including the environment for decision not only in the community but within the deciding body itself); (3) planning and action strategies; and (4) issue attributes. Using this framework, a series of hypotheses are posed for future research, and the potential implications for urban planning are discussed.

Hordenine, gramine, and an unknown compound assigned the structure of 2,9-dimethyl-6-methoxy-1,2,3,4-tetrahydro-β-carboline and n-octacosanol were isolated from Phalaris arundinaceaVar. Ottawa Synthetic C grown in Manitoba. The compounds were separated by a counter current distribution method followed by column chromatography on Woelm basic alumina, and were characterized by the use of infrared, ultraviolet, mass, and nuclear magnetic resonance spectroscopy.