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Presents the case of a patient who developed severe chronic hemolytic anemia after replacement of a defective aortic valve with a Starr-Edwards ball valve prosthesis. Potential role of intravascular coagulation in processes of intravascular hemolysis in patients with defective aortic valve prosthesis; Implications of intravascular coagulation for red cell destruction in valvular heart disease; Effect of heparin on the management of hemolytic anemia in patients.