Search

Your search keyword '"Dronabinol chemical synthesis"' showing total 24 results
Start Over Descriptor "Dronabinol chemical synthesis" Publication Year Range More than 50 years ago
24 results on '"Dronabinol chemical synthesis"'

3. Brain levels and relative potency of the 1,2-dimethylheptyl analogue of delta1-tetrahydrocannabinol in mice.

Author

Lawrence DK, Pertwee RG, Gill EW, and Piper JM

Subjects
Animals, Chromatography, Gas, Dronabinol chemical synthesis, Dronabinol metabolism, Dronabinol pharmacology, In Vitro Techniques, Isomerism, Isotope Labeling, Liver metabolism, Male, Mass Spectrometry, Mice, Mice, Inbred Strains, Motor Activity drug effects, Tritium, Brain Chemistry drug effects, Cannabis analogs & derivatives, Dronabinol analogs & derivatives
Published
1974
Full Text
View/download PDF

4. [Hashish--chemistry and problems].

Author

Bieniek D, Gau W, and Korte F

Subjects
Animals, Chemical Phenomena, Chemistry, Columbidae, Dogs, Dronabinol chemical synthesis, Dronabinol metabolism, Dronabinol toxicity, Drug Tolerance, Humans, Macaca, Rats, Structure-Activity Relationship, Aza Compounds chemical synthesis, Cannabis chemical synthesis
Published
1974
Full Text
View/download PDF

11. [Chemistry of synthetic cannabis derivatives].

Author

Petrzilka T

Subjects
Alkaloids isolation & purification, Cannabis analysis, Chemical Phenomena, Chemistry, Chromatography, Gas, Dronabinol chemical synthesis, Methods, Cannabis chemical synthesis
Published
1971

13. [Cannabis].

Author

Nishioka I

Subjects
Chemical Phenomena, Chemistry, Dronabinol chemical synthesis, Cannabis isolation & purification, Cannabis pharmacology
Published
1971

14. Water-soluble derivatives of 1 -tetrahydrocannabinol.

Author

Zitko BA, Howes JF, Razdan RK, Dalzell BC, Dalzell HC, Sheehan JC, Pars HG, Dewey WL, and Harris LS

Subjects
Amphetamine pharmacology, Animals, Behavior, Animal drug effects, Blood Pressure drug effects, Depression, Chemical, Dogs, Dronabinol administration & dosage, Dronabinol chemical synthesis, Dronabinol pharmacology, Drug Interactions, Epinephrine pharmacology, Imines, Infrared Rays, Injections, Intravenous, Magnetic Resonance Spectroscopy, Motor Activity drug effects, Norepinephrine pharmacology, Solubility, Spectrum Analysis, Cannabis chemical synthesis
Abstract

Delta1-Tetrahydrocannabinol, which is resinous and insoluble in water and therefore difficult to study pharmacologically, can be converted to a watersoluble derivative without loss of its biological activity. This has been achieved by preparing esters bearing a nitrogen moiety with the use of carbodiimide as the condensing agent. The availability of such water-soluble derivatives will allow the evaluation of Delta1-tetrahydrocannabinol in self-administration studies in monkeys for its addiction liability potential in man. This technique of water solubilization is also applicable to other compounds of chemical and biological significance.

Published
1972
Full Text
View/download PDF

16. Tolerance to the behavioral effects of marihuana in chimpanzees.

Author

Ferraro DP and Grisham MG

Subjects
Animals, Behavior, Animal drug effects, Dose-Response Relationship, Drug, Dronabinol chemical synthesis, Dronabinol pharmacology, Female, Male, Pan troglodytes, Plant Extracts pharmacology, Reinforcement Schedule, Cannabis pharmacology, Conditioning, Operant drug effects, Drug Tolerance
Published
1972
Full Text
View/download PDF

18. Chemistry of marihuana.

Author

Waller CW

Subjects
Animals, Behavior, Animal drug effects, Bile analysis, Bile metabolism, Chromatography, Gas, Dronabinol analysis, Dronabinol blood, Dronabinol chemical synthesis, Dronabinol isolation & purification, Dronabinol metabolism, Dronabinol pharmacology, Dronabinol urine, Drug Tolerance, Feces analysis, Kidney metabolism, Liver metabolism, Microsomes, Liver metabolism, NADP, Optical Rotation, Plant Extracts, Plants analysis, Seeds analysis, Smoke analysis, Smoking, Tritium, Cannabis analysis, Cannabis chemical synthesis, Cannabis isolation & purification, Cannabis metabolism, Cannabis urine
Published
1971

20. Structure-activity relationships in the tetrahydrocannabinol series. Modifications on the aromatic ring and it the side-chain.

Author

Edery H, Grunfeld Y, Porath G, Ben-Zvi Z, Shani A, and Mechoulam R

Subjects
Alkylation, Animals, Behavior, Animal drug effects, Chemical Phenomena, Chemistry, Cyclization, Dogs, Dronabinol chemical synthesis, Dronabinol pharmacology, Female, Haplorhini, Macaca, Male, Motor Activity drug effects, Phenols, Pyrans, Radiochemistry, Cannabis pharmacology, Structure-Activity Relationship
Published
1972

23. Photochemical studies of marijuana (cannabis) constituents.

Author

Allwardt WH, Babcock PA, Segelman AB, and Cross JM

Subjects
Chromatography, Gas, Dronabinol chemical synthesis, Dronabinol isolation & purification, Dronabinol radiation effects, Magnetic Resonance Spectroscopy, Mass Spectrometry, Optical Rotation, Photochemistry, Spectrum Analysis, Time Factors, Ultraviolet Rays, Cannabis radiation effects
Published
1972
Full Text
View/download PDF

24. General pharmacological actions of some synthetic tetrahydrocannabinol derivatives.

Author

Hardman HF, Domino EF, and Seevers MH

Subjects
Animals, Antihypertensive Agents pharmacology, Barbiturates pharmacology, Behavior, Animal drug effects, Blood Pressure drug effects, Body Temperature Regulation drug effects, Cats, Central Nervous System drug effects, Dogs, Dronabinol chemical synthesis, Dronabinol pharmacology, Drug Combinations, Drug Interactions, Drug Synergism, Drug Tolerance, Haplorhini, Heart Rate drug effects, Hypotension chemically induced, Hypothermia chemically induced, Macaca, Mice, Reserpine pharmacology, Respiration drug effects, Sleep drug effects, Structure-Activity Relationship, Time Factors, Cannabis pharmacology
Published
1971

Catalog

Books, media, physical & digital resources
See catalog results