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H-2 crossovers and their parental strains were arranged into 35 combinations in which the adult donor of spleen cells differed from the newborn recipient in the whole H-2 complex, or in three, two, or one region of the complex. A Simonsen splenomegaly assay was then used to test the contribution of the individual H-2 regions to the graft-versus-host reaction (GVHR). It was shown that the strongest GVHR was associated with the Ir region. Differences in the Ir region caused significant splenomegaly in spite of the fact that no antigens detectable by conventional serological methods have thus far been associated with this region. Differences in the K and D regions showed only a borderline effect on GVHR in spite of the fact that these regions code for most, if not all, of the antigens detectable by conventional serological and transplantation methods. The K region alone caused no stronger GVHR than the D legion alone; however, K + Ir region differences led to much stronger GVHR than D region differences. The Ss-Slp region also showed only a borderline effect on GVHR. Differences in two or more H-2 regions usually caused greater splenomegaly than differences in each of the regions separately. On the basis of these findings it is concluded that the strongest GVHR is caused by genes distinct from the known histocompatibility genes of the H-2 complex. It is speculated that the GVHR genes are identical with the mixed lymphocyte reaction (MLR) and Ir genes and that the product of these genes are receptors on the surface of the thymus-derived lymphocytes (T cells).

PURPOSE: To compare the mid-term clinical results of arthroscopic and open repair for large to massive rotator cuff tear.MATERIALS AND METHODS: We retrospectively reviewed 48 patients who underwent either arthroscopic or open repair for large to massive rotator cuff tear. 28 patients underwent arthroscopic repair and 20 patients had open repair. The clinical outcome for the 2 groups was evaluated using range of motion, Visual Analogue Scale (VAS) for pain and function, American Shoulder and Elbow Society (ASES) score and Korean Shoulder Scoring System (KSS) score.RESULTS: The range of motion, VAS for pain and function and ASES score was improved significantly in both groups at the final follow-up visit compared with preoperative values. However, there were no significant differences between the two groups statistically (p>0.05). There were no significant differences between the two groups statistically at the final follow-up KSS score (p>0.05) either.CONCLUSION: We could obtain improved mid-term clinical outcomes in both arthroscopic repair and open repair without any statistically significant differences between the two groups.

Until now microsatellite (MS) have been a popular choice of markers for parentage verification. Recently many countries have moved or are in process of moving from MS markers to single nucleotide polymorphism (SNP) markers for parentage testing. FAO-ISAG has also come up with a panel of 200 SNPs to replace the use of MS markers in parentage verification. However, in many countries most of the animals were genotyped by MS markers till now and the sudden shift to SNP markers will render the data of those animals useless. As National Institute of Animal Science in South Korea plans to move from standard ISAG recommended MS markers to SNPs, it faces the dilemma of exclusion of old animals that were genotyped by MS markers. Thus to facilitate this shift from MS to SNPs, such that the existing animals with MS data could still be used for parentage verification, this study was performed. In the current study we performed imputation of MS markers from the SNPs in the 500-kb region of the MS marker on either side. This method will provide an easy option for the labs to combine the data from the old and the current set of animals. It will be a cost efficient replacement of genotyping with the additional markers. We used 1,480 Hanwoo animals with both the MS data and SNP data to impute in the validation animals. We also compared the imputation accuracy between BovineSNP50 and BovineHD BeadChip. In our study the genotype concordance of 40% and 43% was observed in the BovineSNP50 and BovineHD BeadChip respectively.

An experimental study has been carried out to investigate the effects of spinning conditions on the shape of fibers spun through noncircular spinnerette holes, namely, rectangular holes, trilobal holes, and round holes with lugs. For the study, bench-scale apparatuses of wet spinning and melt spinning were used which had been constructed in connection with an earlier study by Han. In the wet-spinning experiment, the spin dope used was an aqueous solution of polyacrylonitrile (PAN) consisting of approximately 10% polymer and 40% sodium thiocyanate (NaSCN), and the spin dope was spun into aqueous solutions of NaSCN. In the melt-spinning experiment, polystyrene was used. The variables investigated were: size and shape of the spinnerette hole, coagulating bath concentration, throughput rate, and jet stretch. It has been found in wet spinning that, for a given shape of spinnerette hole, the fiber shape is most strongly affected by jet stretch and relatively little by the bath concentration and throughput rate. Also determined in the wet-spinning experiment was the maximum jet stretch at which thread breakage occurs. It has been found that the maximum jet stretch decreases as bath concentration is increased.

(1960). Developments in the Use o f the A.I.S.I. Automatic Smoke Sampler. Journal of the Air Pollution Control Association: Vol. 10, No. 4, pp. 303-306.

The thermodynamic critical field has been determined calorimetrically for Pb 0.9 Bi 0.1 . A prediction that the deviation function will be very large is not sustained. D ( t ) is only slightly larger than for pure Pb, in very good agreement with more recent calculations.