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The purpose of the present study was to explore the effects of a tranquilizing drug, chlorpromazine, on visual sensitivity and its modification in the presence of intersensory stimulation. The mutually recruitable neurone (MRN), a construct formulated in recent research on intersensory effects, provided a theoretical framework in which observed drug effects might be interpreted. Prior studies on intersensory effects have suggested that sensitivity in a primary sensory system first increases and then decreases as a function of the increasing intensity of the accessory stimulation, producing in turn both facilitation and inhibition. The literature on chlorpromazine has suggested that it might have effects on sensory processes but the magnitude and direction of these effects have varied with experimental conditions and there is need for further clarification. [truncated]