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In order to determine the ultimate molecular resolution attainable with a conventional electron microscope, the direct observation of hexadecachloro‐Cu‐phthalocyanine molecules was attempted. Since phthalocyanine derivatives are known to form crystalline films with columns of parallel stacks of planar molecules, the specimens were prepared by epitaxial growth on KCl cleavage face through vacuum evaporation so that the column axis was directed almost normal to the thin‐film surface holding an orientation suitable for the observation. The molecular orientation was determined by Patterson synthesis based on the laser optical transform of the electron diffraction pattern obtained from the individual crystallites placed on the microgrid mesh. The direct observation was carried out with the 100‐kV electron beam incident on the specimen along the column axis. The crosslike images arrayed in a centered rectangular net were clearly resolved, well representing the molecular shape of phthalocyanine with the configur...

The following results were obtained on the physical development of pupils residing in mountain villages in the Aizu district, Fukushima Prefecture as compared with that Of those in cities and agricultural villages of the same district.1. The height development of pupils in mountain villages was inferior to those in cities and agricultural villages, the tendency being conspicuous among female pupils at the lower grades. Although the pupils at the 3rd grade of junior high schools exceptionally surpassed again in height of the female pupils, no such a tendency was seen in the weight of the body and the girth of the chest. No remarkable difference was observed in the weight of the body. As regards the girth of the chest, pupils in the mountain villages was superior contrarily, the tendency being conspicuous among female pupils at the higher grades.2. As regards the height, the weight of the body and the girth of the chest, the male pupils were superior to the female pupils in case of the lower grades, whereas the female pupils preceded the male pupils in case of the higher grades. The age at which the female pupils surpassed in height and weight the male pupils was belated in the mountain villages than in cities and agricultural villages. However, with regard to the girth of the chest, the age at which the female pupils surpassed the male pupils showed no difference by geographical distribution.3. The Rohrer's index was the highest in the mountain villages, being followed in the order of agriculturcal villages, and cities. The index decreased both in male and femals pupils in proportion to the increase of age. However, the increase of the index on the part of the female pupils in the junior high schools seemed attributable to earlier maturing age of physical development in the female pupils as compared with the male pupils.4. The results of the investigation on the weight at 'the time of birth was carried out to clarify the reason for tne inferiority of physical development of the pupils in the mountain villages. It was found that the average values in the mountain villages were rather superior to the standard values. When the investigation was made on the weight of the body of sucklings and infants in the mountain villages, the increase of the weight was decreased gradually since 4 months after the birth, attaining the maximum around the 12 months the birth. Lastly, it was also found that the commencement of ablactation was exceedingly delayed in the mountain villages. In view of the abovementioned facts, the geographical difference of physical development seems to be initiated from the weaning period

Submicroscopic topographies of oxidized stibnite and of etched zincblende were examined by electron microscopes. Crystallites of antimony oxide formed on stibnite have a roof-like shape bounded by two well-developed and four less developed {111} faces. This is in agreement with the conclusion drawn previously from electron diffraction study (Miyake, Sc. Pap. I. P. C. R. 34 (1938), 565). The direct observation by electron microscope gives some further information on the growth of the oxide. Zincblende surfaces etched by hydrochloric acid has a shape which is slightly different from the negative triakis tetrahedron inferred from electron diffraction study (Uyeda et al., Proc. Phys. -Math. Soc. Japan 24 (1941) 1049). In the diffraction patterns from this surface, structures of reflexion spots finer than those previously reported were observed and analysed by the theory of the dynamical refraction effect.

Examination of Cellulose Fibre by the Low-Temperature Specimen Method of Electron Diffraction and Electron Microscopy

The effect of prolonged administration of synthetic LH-RH (400 mug daily im for 5 days) on gonadotropin response to LH-RH (100 mug single injection iv) was compared in 13 patients with pituitary tumors or suprasellar tumors. No patients with pituitary tumors exhibited an augmented response on serum FSH and LH after prolonged LH-RH administration. A paradoxical fall in response to LH-RH test occurred in 3 patients with pituitary tumors and in a patient with hypothalamic tumor in whom gonadotropin responses were normal on the first LH-RH test. On the other hand, 2 patients with suprasellar tumors with a low response to the initial LH-RH test showed significant increase on a second LH-RHtest after consecutive LH-RH administration. Consecutive administration of LH-RH may help to distinguish between the hypogonadism of pituitary origin and that of hypothalamic origin when the initial LH response to a single dose of LH-RH is subnormal.