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Radiation therapy has been officially recognised as an efficient cancer treatment at the International Oncology Congress in Paris on 1922, 25 years after the discovery of X-rays by W. Roentgen and since then tremendous progresses have been made on the basic knowledge on the biological effects of radiations on tumours and healthy tissues, on the modalities and times for dose delivery, planning and irradiation techniques. It may be used as the primary therapy or combined with surgical or medical therapies or to prevent serious symptoms related to the progression of the disease. In recent years the availability of new technologies and results coming from interdisciplinary research where medical and biological competences are working in strict collaboration with physicists and engineers have contributed to a substantial improvement of this treatment by introducing new concepts and procedures which are presented in this paper. The planning treatment has been revolutionised by the possibility to identify in quantitative way tumours and adjacent normal structures in 3D by image processing of CT and/or MRI and/or PET and using virtual simulation for more accurate placement of radiation beams. An enhancement of this technique is £-Dimensional Conformal Radiotherapy (3DCRT) in which the profile of radiation beam is shaped to fit the profile of the target using a multileaf collimator. In radiosurgery and stereotactic radiotherapy the needed accuracy requires special new techniques to better control the uncertainty related to internal organ motion (for example due to respiration) with real-time adjustment of the radiation beam. The latest developments of Radioisotope Therapy Intra Operative Radiation Therapy and Hadrontherapy are also illustrated.

3D virtual representation of garment provides high potential for design, product development and marketing processes, especially in mass customization strategies implementation. Clothing industry rapidly turns to virtual simulation which not only presents realistic 3D view of garment but also simulates mechanical behaviour of materials. 3D CAD systems can be used to define strain distribution in virtual garment which describes garment fit without actually producing the garment. Strain and distance ease between body and garment depends not only upon body measurements and garment construction, but also on mechanical and structural properties of selected material. The aim of this research was to investigate virtual garment fit using "Modaris 3D Fit" (Lectra) software subjected to fabrics mechanical (tensile, bending, shear) and structural (composition, thickness, area density) properties investigating strain distribution in garment and distance ease between garment and human body. It was defined that for diagonal cut garments the highest influence upon garment fit has fabric tensile properties in weft direction. The highest influence is obtained at high distance ease and small strain values zones and at negative distance ease and high strain values zones. Therefore, presented method could be used for tight-fitted garments also for garments with draperies on purpose to investigate garment fit upon fabrics used.http://dx.doi.org/10.5755/j01.ms.17.2.486