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T HE CURRENT status of acne therapy is aptly recalled by a letter recently received from a sufferer. It is quoted in part: I am a private in the Army, seventeen years old and suffering with acute acne, I have had it for three years. The doctors seem to pass me as just another case, giving me some ointment and saying if that does not help, we will try something else, with the something else always failing. What I would like to know . . . . is there any sure cure for acne? With all these new drugs, there must be one that will help. I am not speaking only for myself but for hundreds of other guys who have acne also. Please let me know, what I can do. For many years, acne has been suspected of being related to the androgenicestrogenic metabolism.1Acne is rarely observed in eunuchs. Lawrence