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A teen-age patient, who became virilized in the course of pregnancy is described. The virilizing syndrome was due to a serous cystadenoma of the ovary. A marked difference in plasma testosterone concentration between specimens obtained preoperatively and postoperatively was demonstrated, indicating testosterone secretion by the neoplasm. Virilization regressed completely by the sixth postoperative month. The patient became pregnant one year after tumor resection and delivered a normal male infant. This report represents the first serous cystadenoma associated with virilization in pregnancy. The literature on the subject is reviewed.

A case is reported of torsion of an ovarian cystadenoma in a 101-year-old woman. The tumor was removed surgically. The noteworthy features of the case were the rarity of this complication in such an aged woman, the presence of clinical and radiological signs that made the correct diagnosis possible before operation, and the remarkable tolerance to surgery displayed by the centenarian patient.