1. A novel Zn2+-coordination fluorescence probe for sensing HPPD inhibitors and its application in environmental media and biological imaging.
- Author
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Chen, Panpan, Xu, Chenyang, Qiu, Yang, and Wang, Yi
- Subjects
POLLUTANTS ,AGRICULTURE ,POLLUTION ,FLUORESCENT probes ,FLUORESCENCE ,HERBICIDES - Abstract
Mesotrione, topramezone, tembotrione, and sulcotrione are four types of 4-hydroxyphenylpyruvate dioxidase (HPPD) inhibitor herbicides that are extensively employed in agricultural practices, but their usage also leads to environmental pollution and poses risks to human health. A probe (E)−1-((2-(pyridin-2-yl) hydrazineylidene) methyl) naphthalen-2-ol (CHMN) based on chelation enhancement (CHEF) effect synthesized. CHMN was first chelated with Zn
2+ to form a probe system with green, which can be further used to detect mesotrione, topramezone, tembotrione and sulcotrione in complicated environment. CHMN-Zn2+ detection of four pesticides was accurate, with an excellent linear relationship between 0 and 100 μM. The detection limits were LOD mesotrione = 7.79 μM, LOD topramezone = 1.91 μM, LOD tembotrione = 1.38 μM and LOD sulcotrione = 2.43 μM. The detection time is 1 min, and it is successfully applied in real water sample and bioimaging. This work can provide a novel method for studying the migration and behavior of environmental pollutants. [Display omitted] • A novel Zn2+ -coordination fluorescent probe for sensing HPPD inhibitors was synthesized. • CHMN has low cytotoxicity, high sensitivity and and good selectivity. • CHMN can detect HPPD inhibitors in environmental water samples. • CHMN can visualize the migration and behavior of HPPD inhibitors in vivo in real time. [ABSTRACT FROM AUTHOR]- Published
- 2024
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