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SoxB subfamily is an important branch of Sox family and plays a key role in animal physiological process, but little is known about their function in planarian regeneration. This study aims to evaluate the function of DjSoxB family genes in intact and regenerating planarians Dugesia japonica. Here, we amplify the full-length cDNA of DjSoxB1 and DjSoxB2 in D. japonica by rapid amplification of the cDNA ends (RACE), detect the expression of DjSoxB family genes in planarian. The results show that DjSoxBs are expressed in parenchymal tissue and the hybridization signals partially disappear after irradiation indicates DjSoxB family genes are expressed in neoblasts. After the RNA interference (RNAi) of DjSoxB1, DjSoxB2 and DjSoxB3 separately, the numbers of proliferative cells are all reduced that causes planarians show slower growth of blastema in the early stage of regeneration, and nerves of planarians are affected that the movement speed of planarians decreases in varying degrees. Specially, planarians in the DjSoxB3 RNAi group show shrinkage and twisting. Overall, this study reveals that DjSoxB family genes play a role in cell proliferation during regeneration. They also play an important role in the maintenance of normal nerve function and nerve regeneration. These results provide directions for the functional study of SoxB family genes and provide an important foundation for planarian regeneration. [ABSTRACT FROM AUTHOR]

In this paper, we focus on exploring effective methods for faster and accurate semantic segmentation. A common practice to improve the performance is to attain high-resolution feature maps with strong semantic representation. Two strategies are widely used: atrous convolutions and feature pyramid fusion, while both are either computationally intensive or ineffective. Inspired by the Optical Flow for motion alignment between adjacent video frames, we propose a Flow Alignment Module (FAM) to learn Semantic Flow between feature maps of adjacent levels and broadcast high-level features to high-resolution features effectively and efficiently. Furthermore, integrating our FAM to a standard feature pyramid structure exhibits superior performance over other real-time methods, even on lightweight backbone networks, such as ResNet-18 and DFNet. Then to further speed up the inference procedure, we also present a novel Gated Dual Flow Alignment Module to directly align high-resolution feature maps and low-resolution feature maps where we term the improved version network as SFNet-Lite. Extensive experiments are conducted on several challenging datasets, where results show the effectiveness of both SFNet and SFNet-Lite. In particular, when using Cityscapes test set, the SFNet-Lite series achieve 80.1 mIoU while running at 60 FPS using ResNet-18 backbone and 78.8 mIoU while running at 120 FPS using STDC backbone on RTX-3090. Moreover, we unify four challenging driving datasets (i.e., Cityscapes, Mapillary, IDD, and BDD) into one large dataset, which we named Unified Driving Segmentation (UDS) dataset. It contains diverse domain and style information. We benchmark several representative works on UDS. Both SFNet and SFNet-Lite still achieve the best speed and accuracy trade-off on UDS, which serves as a strong baseline in such a challenging setting. The code and models are publicly available at https://github.com/lxtGH/SFSegNets. [ABSTRACT FROM AUTHOR]

Motivated by biological evolution, this paper explains the rationality of Vision Transformer by analogy with the proven practical evolutionary algorithm (EA) and derives that both have consistent mathematical formulation. Then inspired by effective EA variants, we propose a novel pyramid EATFormer backbone that only contains the proposed EA-based transformer (EAT) block, which consists of three residual parts, i.e., Multi-scale region aggregation, global and local interaction, and feed-forward network modules, to model multi-scale, interactive, and individual information separately. Moreover, we design a task-related head docked with transformer backbone to complete final information fusion more flexibly and improve a modulated deformable MSA to dynamically model irregular locations. Massive quantitative and quantitative experiments on image classification, downstream tasks, and explanatory experiments demonstrate the effectiveness and superiority of our approach over state-of-the-art methods. E.g., our Mobile (1.8 M), Tiny (6.1 M), Small (24.3 M), and Base (49.0 M) models achieve 69.4, 78.4, 83.1, and 83.9 Top-1 only trained on ImageNet-1K with naive training recipe; EATFormer-Tiny/Small/Base armed Mask-R-CNN obtain 45.4/47.4/49.0 box AP and 41.4/42.9/44.2 mask AP on COCO detection, surpassing contemporary MPViT-T, Swin-T, and Swin-S by 0.6/1.4/0.5 box AP and 0.4/1.3/0.9 mask AP separately with less FLOPs; Our EATFormer-Small/Base achieve 47.3/49.3 mIoU on ADE20K by Upernet that exceeds Swin-T/S by 2.8/1.7. Code is available at https://github.com/zhangzjn/EATFormer. [ABSTRACT FROM AUTHOR]