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Few studies have examined changes in skeletal muscle physiology post-stroke. This study examined changes in tissue oxygen saturation (StO2) of the vastus lateralis (VL) muscle of stroke survivors and age-matched control participants during maximal and submaximal isometric contractions of the knee extensor muscles. We hypothesized that tissue oxygen desaturation (ΔStO2) during knee extensor muscle contractions would be less in the VL in the paretic vs. the non-paretic and control legs. Ten chronic stroke survivors (>6 months post-stroke) with lower extremity muscle weakness and 10 age-matched controls completed this prospective cohort study. Maximum voluntary contractions (MVCs) of the knee extensor muscles were assessed with a Biodex dynamometer and StO2 of the VL was measured using near-infrared spectroscopy. In the paretic leg of the stroke survivors little change in StO2 of the VL was observed during an MVC (ΔStO2 = -1.7 ± 1.8%) compared to the non-paretic (ΔStO2 = -5.1 ± 6.1%; p < 0.05) and control legs (ΔStO2 = -14.4 ± 8.8%; p < 0.05 vs. paretic and non-paretic leg). These differences remained when normalizing for strength differences between the legs. Compared to controls, both the paretic and non-paretic VL showed pronounced reductions in ΔStO2 during ramp and hold contractions equal to 20%, 40%, or 60% of the MVC (p < 0.05 vs. controls at all load levels). These results indicate that oxygen desaturation in response to isometric muscle contractions is impaired in both the paretic and non-paretic leg muscle of stroke survivors compared to age-matched controls, and these differences are independent of differences in muscle strength. [ABSTRACT FROM AUTHOR]

A line of 25 cull cows were all found to have ulcerative lesions of the tongue at post-mortem inspection in a New Zealand slaughter plant. A further 9 of 10 cows inspected at the farm of origin had similar oral lesions. There were no other clinical signs or indicators of ill-health observed at ante-mortem inspection in the abattoir or on the farm. The cows had been fed baleage for 3 weeks prior to slaughter, made from pasture in paddocks heavily contaminated with yellow bristle grass (Setaria pumila). There was extensive and deep transverse linear ulceration in the lingual fossa immediately rostral to the torus linguae. At histological examination, full-thickness ulceration of the stratified squamous epithelium was observed with a bed of disorganised collagenous tissue and extensive mixed inflammatory infiltrate extending into the sub-epithelial connective tissue and skeletal muscle. Barbed plant fragments were embedded in both the superficial and deeper areas of inflammation. Detailed examination of the baleage also found that yellow bristle grass seedheads were present. Based on the presence of barbed plant material in the tongue and yellow bristle grass seeds in the baleage, a diagnosis of ulcerative stomatitis associated with yellow bristle grass was made. Clinicians should be aware of the potential for hay or baleage contaminated with yellow bristle grass to cause oral lesions in cattle. [ABSTRACT FROM AUTHOR]

This paper presents a critical review of the reasons behind the initiation of this project to find a more sustainable, cost efficient, and safer form of chloride extraction that would result in stabilisation of archaeological copper and its alloys with tin and zinc. The imperative has become increasingly strident with cutbacks in funding for museum conservation facilities and with the reduction in staff, leaving less time for routine analyses of traditional immersive washing treatments that could take several years to effect. Owing to the faster oxidation and reduction kinetics of copper, compared with tin and zinc ions, the problems of uncontrolled corrosion of copper alloys in a chloride-rich environment have led to unacceptable levels of decay in heritage collection items. This study looked at the chloride extraction rates under subcritical conditions for both primary and secondary chloride-rich mineral species nantokite, clinoatacamite, and atacamite and determined the impact of changing the solution pH from 8 to 10, while also addressing the impact of temperature. The range of temperatures between 130 and 230°C was assessed at 50°C intervals at both levels of acidity of the leaching liquors. For the nantokite treatment, the formation of a cuprite patina which replaced the waxy-grey initial corrosion products was regarded as a bonus. The nature of the patina and changes in surface textures resulting from the treatment are critically reviewed and a series of recommendations for future work are included in the conclusion. [ABSTRACT FROM AUTHOR]

This paper coordinates archaeological information on the changing urban landscape of Egypt's first Islamic-era capital, Fustat, with topographical, social, and economic insights from the Geniza archive and other sources. A focus on the organization of the city's pottery industry provides new insights into the multiple "abandonments" and reoccupations familiar from historical sources, showing how diverse residential areas were turned to industrial use (and back) via adaptable transitional processes. [ABSTRACT FROM AUTHOR]

Objectives: The purpose of this study was to identify the 50 most-cited publications relating to lacrosse since 1990 and conduct a bibliometric analysis of the identified studies Methods: Clarivate Analytics Web of Science database was queried to identify all publication titles, abstracts, and keywords for the term 'lacrosse' on 9 June 2023. The resulting articles were sorted by total number of citations. Titles and abstracts were included based on their relevance to lacrosse. Once the 50 most cited articles were identified, each article was further analyzed to obtain author name, publication year, country of origin, journal name, article type, research topic, competition level, total number of citations, and the level of evidence. Citation density (total number of citations/years since publication) was calculated and recorded for each of the most-cited studies. Results: The 50 most-cited articles were cited 4237 of times with an average of 84 citations per article. The most cited article was cited 637 (15.0%) times. The articles came from 2 different countries, with the United States and Australia comprising 49 and 1 articles, respectively. All articles were published in English. The American Journal of Sports Medicine published the most articles (n = 21, 42.0%). The most studied topic was concussion/traumatic brain injury (n = 18) followed by studies assessing all injuries (n = 7). Collegiate-level lacrosse was the most studied level of competition (n = 22), while high school-level followed (n = 12). Conclusions: The majority of the 50 most-cited articles related to lacrosse since 1990 focus on the prevalence, diagnosis and identification of concussion/traumatic brain injury in high school and collegiate-level athletes. These articles are predominantly epidemiological or cohort studies with Level III or IV evidence that almost unanimously originate from the United States. [ABSTRACT FROM AUTHOR]

Animal-visitor interactions are common in captive-wildlife tourism settings, but there is a lack of research exploring what is on offer. This study defines and examines 'Meet & Greet' animal experiences in UK zoos within the context of the wider wildlife tourism industry, considering the differences between semi-contrived and fully-contrived interactions. From quantitatively analysing the websites of members of the British and Irish Association of Zoos and Aquariums, the results show that Meet & Greets are frequently offered by zoos in the UK, but that these zoos do not always explicitly describe what the interaction involves. We propose that there is a need for more research on the impact of Meet & Greets, particularly looking at how zoos advertise these experiences and how they are perceived by potential participants, as there is a danger that accredited zoos could inadvertently be promoting the exploitation of animals for photo prop opportunities in other tourist settings. [ABSTRACT FROM AUTHOR]

Tourism studies pay relatively little attention to the importance of reflexivity and metacognition. This article highlights the integral importance of explicitly considering reflexivity and metacognition issues as part of the research process when studying pro-poor tourism (PPT). Hence, the paper presents a reflexive and metacognitive account of the challenges and obstacles encountered while undertaking ethnographic fieldwork in PPT. Drawing on the first author's research experiences in Vietnam with informal tourism workers, it reflects the positional, ethical, and methodological challenges faced during and after the fieldwork. This article is the first to provide a critical reflection on fieldwork in PPT, thereby adding to the conceptual recognition of the importance of reflexivity and metacognition in tourism studies overall. It also shares deeper insights into the difficulties associated with research that involves poor people, whose voices remain largely absent from tourism studies. [ABSTRACT FROM AUTHOR]

Copyright of Studies in Conservation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

CEA has manufactured a series of Fukushima Daiichi fuel debris simulants, either with depleted uranium oxide or with hafnium oxide as a surrogate of UO2. In ex-vessel compositions resulting from an interaction between corium and concrete, the oxidic phase density becomes lighter than that of the metallic phase, which segregates at the bottom. Three of these metallic phases have been mechanically cut at CEA Cadarache with handsaw and with core boring tool in FUJISAN facility. It appeared that two of these metallic blocks were extremely hard to cut (one from a fabrication with uranium oxide, the other from a simulant block) while the last one was more easily cut. The similarities and differences in metallographic analyses (SEM-EDS and XRD) of these three metal blocks will be presented and discussed. This experience provides useful learnings in view of the cutting and retrieval of fuel debris from Fukushima Daiichi. [ABSTRACT FROM AUTHOR]

In order to study the use of drying models in vacuum-infrared drying, an experiment was conducted to investigate the drying process of cherry pips at different temperatures of 60°C, 70°C and 80°C, drying characteristic curves were constructed and analysed using 6 types of thin layers, and effective diffusion coefficients, moisture content and activation energy were calculated. The results showed that the drying temperature has a greater influence on the drying rate of cherry pits, and the drying time decreases with increasing drying temperature. The main drying step occurs in the downward drying stage. Comparison of the fitting results of the six thin layer drying models presented in this paper showed that Wang and Singh's model fits better for cherry pips (${{\rm{R}}^2} \gt 0,9996$ R 2 > 0 , 9996) and the predicted values of the model agree well with the experimental values. These values are suitable for describing the drying characteristics of cherry pips under any conditions. T. [ABSTRACT FROM AUTHOR]

In the present work, Al-doped (0, 1, 2 and 3%) ZnO nanoparticles (NPs) are synthesised by green combustion method (GCM) using Terminalia Catappa seeds (TCS) extract as a novel fuel. For the synthesis Zinc nitrate and Aluminum nitrate are used as precursor and dopant respectively. The synthesised NPs are characterised by XRD, FTIR, UV-vi and impedance spectroscopy. The XRD analysis shows decrease in crystallite size varies between 40 to 26 nm as dopant increases. The FTIR spectrum reaffirms the formation of Zn-O bonding structure at 454.28 cm−1. UV-Vi spectroscopic studies show the optical band gap of 3.63, 3.53, 3.22 and 3.19 eV for Al doped (0, 1, 2 and 3%) ZnO NPs. Thermal analysis for the synthesised Al-doped (0, 1, 2 and 3%) ZnO nanoparticles are analysed using TGA/DTA studies. The Electrical characteristics are studied at various temperatures (50 to 350°C) by varying frequency (10 Hz to 8 MHz). In low frequency regions, dielectric constant and dielectric loss increases with rise in temperature. The constant AC conductivity is observed in lower frequencies and increases for higher frequencies for all doped ZnO NPs. ZnO NPs prepared with 2% of doping exhibit improved structural and electrical properties. Hence these ZnO NPs may be used as sensing material for vibration sensor. Highlights: This paper focus on green synthesis of undoped and Al-doped ZnO nanoparticles by combustion method. ZnO nanoparticles are synthesised using zinc nitrate precursor, Aluminium nitrate as dopant and Terminalia catappa seed extract as fuel. Effect of Al (0, 1,2 and 3%) doping on microstructural, optical, thermal and electrical properties of ZnO nanoparticles are investigated. The green synthesised doped and undoped ZnO nanoparticles exhibit hexagonal wruzite structure with high crystallinity. The FTIR spectrum reaffirms the formation of Zn-O bonding structure at 454.28 cm-1 The optical band gap is found to be 3.63, 3.53, 3.22 and 3.19 eV for 0, 1,2 and 3% of Al doped ZnO nanoparticles respectively. AC conductivity of ZnO nanoparticles is found to be increased with 2% of Al doped ZnO nanoparticles. Result shows an improved structural, optical and electrical performance for 2% Al doped ZnO nanoparticles and hence these nanoparticles are suitable material for sensors, organic light emitting diodes and liquid crystal displays. [ABSTRACT FROM AUTHOR]

Objective: To study the correlation between condylar morphology and clinical manifestations in patients with degenerative joint disease (DJD) of the temporomandibular joint (TMJ). Methods: A total of 175 joints of 131 patients with DJD were included. Data on patients' basic information and symptoms were collected and analyzed. Condylar morphology was evaluated using cone beam computed tomography (CBCT). The correlation between the condylar morphology and clinical manifestations was analyzed. Results: The prevalence of joint noises, clicks, and crepitus was 93/175 (53%), 73/175 (42%), and 20/175 (11%), respectively. Condylar anteroposterior diameter and condylar height were correlated with pain. There was a correlation between the shape of the condyle in the sagittal plane and joint noise. Conclusion: Condylar morphology and clinical features of DJD were correlated to some extent. [ABSTRACT FROM AUTHOR]

Background: The value of clinical pharmacists for ambulatory internal medicine clinics is well recognized, including their role in hemoglobin A1c (HbA1c) reduction in patients with type 2 diabetes mellitus (T2DM). However, there is a lack of data evaluating the clinical impact of remote, referral-based pharmacy programs. Methods: This multicenter, cohort, retrospective chart review study analyzed the impact of pharmacist interventions on blood glucose control in patients aged 18 years and older who were diagnosed with T2DM with an HbA1c of 8.5% or greater and referred to the clinical pharmacy team for medication evaluation. Primary care providers may have accepted or rejected pharmacist recommendations. The primary study outcome was the mean change in HbA1c from baseline to follow-up at 2 to 5 months. Secondary outcomes included appropriate use of American Diabetes Association–indicated secondary prevention and any occurrence of glycemia-related events (i.e., T2DM-related emergency room visits or hospitalizations). Results: At the conclusion of the study, the mean change in HbA1c from baseline to follow-up at 2 to 5 months was −2.7% and −0.6% for the accepted and rejected intervention groups, respectively (t = −2.94, P = 0.0068). Conclusions: The results of this study suggest that remote pharmacist intervention significantly improves blood glucose control in adults with T2DM. [ABSTRACT FROM AUTHOR]

An 83-year-old man with a history of monoclonal gammopathy of unknown significance, macrocytic anemia, and cytopenias presented with hemorrhagic bullae on his left hand, alongside intermittent fevers and joint pain. Laboratory findings indicated anemia, elevated mean corpuscular volume, thrombocytopenia, leukopenia, and a high C-reactive protein level. A biopsy of the bullae showed neutrophilic dermatosis, and computed tomography scans of the thorax revealed lung opacities and mediastinal lymphadenopathy, suggesting neutrophilic alveolitis. Bone marrow examination found hypercellularity with myeloid and histiocytic hyperplasia, vacuolated precursors, and 3% blasts of an immature myelomonocytic lineage. Genetic testing uncovered a UBA1 mutation at an 81% allele frequency, confirming a diagnosis of VEXAS syndrome. Treatment commenced with prednisone, initiated at 60 mg daily and tapered to 10 mg, with tocilizumab considered for future symptom management. This regimen has successfully maintained remission, as observed in follow-up appointments. This case highlights the diagnostic complexity and effective management of VEXAS syndrome, underscoring the importance of genetic testing in guiding treatment decisions. KEY POINTS: VEXAS syndrome, initially identified in 2020, is a rare disease characterized by overlapping hematologic and rheumatologic conditions, primarily affecting middle-aged to older men. Our case presents a unique instance of VEXAS syndrome, featuring inflammatory symptoms alongside pancytopenia and a history of monoclonal gammopathy of unknown significance, highlighting the diverse clinical spectrum of this condition. The diagnosis was confirmed through bone marrow biopsy revealing vacuoles in myeloid precursors and a UBA1 mutation, reaffirming the diagnostic criteria outlined for VEXAS syndrome. Management challenges persist, with current treatment options limited to glucocorticoids for symptomatic relief, underscoring the need for further research into targeted therapies such as ruxolitinib to improve patient outcomes. [ABSTRACT FROM AUTHOR]

March 2020 will forever be etched in our minds as the beginning of the most concerning health pandemic faced by all generations of the living population. Two-and-three quarter years on, we are starting to see signs for what the future might evolve into through structural change brought about by many events, and no more so than the burgeoning growth in working from home (WFH). WFH is no longer associated with negative stigma, and along with remote working more generally, has become recognised across most sectors of society as a way of work that has benefits for many and is to some extent here to stay. We draw on the research undertaken since March 2020 to summarise the evidence that we use to speculate on what are likely to be the big changes in the land transport sector that would not have been considered, at least to the same extent, pre-COVID-19. [ABSTRACT FROM AUTHOR]

The heat generated by high-level radioactive waste can pose numerical and physical challenges to subsurface flow and transport simulators if the liquid water content in a region near the waste package approaches residual saturation due to evaporation. Here, residual saturation is the fraction of the pore space occupied by liquid water when the hydraulic connectivity through a porous medium is lost, preventing the flow of liquid water. While conventional capillary pressure models represent residual saturation using asymptotically large values of capillary pressure, here, residual saturation is effectively modeled as a tortuosity effect alone. Treating the residual fluid as primarily dead-end pores and adsorbed films, relative permeability is independent of capillary pressure below residual saturation. To test this approach, PFLOTRAN is then used to simulate thermal-hydrological conditions resulting from direct disposal of a dual-purpose canister in unsaturated alluvium using both conventional asymptotic and revised, smooth models. While the two models have comparable results over 100 000 years, the number of flow steps required is reduced by approximately 94%. [ABSTRACT FROM AUTHOR]

This paper provides an overview of ongoing work aimed at developing spent nuclear fuel (SNF) canister deposition models. Currently, it is known that stainless steel canisters are susceptible to chloride-induced stress corrosion cracking (CISCC). However, the rate of CISCC degradation and the likelihood that it could lead to a through-wall crack is unknown. While it is currently unknown if there is a threshold chloride surface concentration for CISCC initiation, it can be assumed that the onset and progress of material degradation will depend on the local contaminant concentration, the properties of the contaminant species, and the synergistic effects when multiple contaminants are present. This study uses well-developed computational fluid dynamics and particle tracking tools and applies them to SNF storage to determine the rate of deposition on canisters. Understanding the rate of deposition on SNF canisters could be important for making canister aging management predictions. This study is a part of an ongoing effort funded by the U.S. Department of Energy, Office of Nuclear Energy, Office of Spent Fuel and Waste Science and Technology, which is tasked with doing research relevant to enhancing the technical basis for ensuring the safe extended storage and subsequent transport of SNF. This work is being presented to demonstrate a potentially useful technique for SNF canister vendors, utilities, regulators, and stakeholders to utilize and further develop for their own designs and site-specific studies. [ABSTRACT FROM AUTHOR]

The siting of nuclear waste is a process that requires consideration of concerns of the public. This report demonstrates the significant potential for natural language processing techniques to gain insights into public narratives around "nuclear waste." Specifically, the report highlights that the general discourse regarding "nuclear waste" within the news media has fluctuated in prevalence compared to "nuclear" topics broadly over recent years, with commonly mentioned entities reflecting a limited variety of geographies and stakeholders. General sentiments within the "nuclear waste" articles appear to use neutral language, suggesting that a scientific or "facts-only" framing of "waste"-related issues dominates coverage; however, the exact nuances should be further evaluated. The implications of a number of these insights about how nuclear waste is framed in traditional media (e.g., regarding emerging technologies, historical events, and specific organizations) are discussed. This report lays the groundwork for larger, more systematic research using, for example, transformer-based techniques and covariance analysis to better understand relationships among "nuclear waste" and other nuclear topics, sentiments of specific entities, and patterns across space and time (including in a particular region). By identifying priorities and knowledge needs, these data-driven methods can complement and inform engagement strategies that promote dialogue and mutual learning regarding nuclear waste. [ABSTRACT FROM AUTHOR]

In the conventional LTE homogeneous network, sufficient transmit power of user equipment (UE) is determined by open-loop power control (OL-PC) and closed-loop power control (CL-PC) schemes. However, in a Het-Net environment, setting the UE’s transmit power requires delicate responsiveness to handle the severe and complicated uplink interference. In this paper, an interference-aware uplink power control mechanism based on Heuristic game theory approach is proposed for devices coexisting in a heterogeneous wireless network. Various wireless constraints like channel response, path loss, fading, shadowing, interference and metrics like SNR, SINR, throughput and bit rates are considered. Uplink power is controlled by suitably selecting the penalization factor (β) based on a simple Heuristic game theory approach considering the possible wireless constraints of each user depending on its location in the cell under consideration. The algorithm is framed in such a way to reduce inter-cell interference, limit transmit power, enhance bit rates and throughput of users. A significant improvement of 5.2% in the user coverage/ distribution is achieved as a result of interference management compared to conventional power control scheme and power control with convex pricing. [ABSTRACT FROM AUTHOR]

Accurately predicting lane changes, a crucial driving activity for preventing accidents and ensuring driver safety, is addressed in this study. An innovative predictive model that integrates game theory for precise lane change intention detection and an optimized Convolutional Neural Network (CNN) for trajectory prediction is proposed in this study. The CNN’s efficiency is enhanced through metaheuristic optimization of both the convolution and fully connected layers using the Whale Optimization Algorithm (WOA). Emphasizing robust data processing, a Wiener filter is applied for pre-processing, and the Cascaded Fuzzy C means (CFCM) technique is employed for segmentation. The resulting Whale Optimization Algorithm-based CNN (WOA-CNN) effectively forecasts the trajectory of lane-changing vehicles. Validation of the proposed approach in Python demonstrates exceptional accuracy, reaching 96.5%. This study showcases the effectiveness of the WOA-CNN model in advancing the prediction accuracy of lane-changing behaviour, contributing to enhanced driver safety and accident prevention. [ABSTRACT FROM AUTHOR]

The aim of this study was to observe the trends in (1) utilization of meniscus allograft transplantation (MAT), (2) demographics and comorbidities of patients undergoing transplants and (3) reimbursements for this procedure between the years of 2010 and 2019. Using a national database, patients who underwent MAT were observed. Incidence of MAT, percentage of female patients, average age, and average Charlson comorbidity index (CCI) were analyzed between 2010 and 2019. Average reimbursement during the index and postoperative 90-day bundle period were also calculated from 2010 to 2019. Compound annual growth rate (CAGR) of change in incidence, demographic and reimbursement was calculated, and linear regressionwas conducted for each trends analysis. In total, 744 patients underwent a MAT between the years of 2010 and 2019. The incidence of MAT increased from 0.12 per 100,000 to 0.15 per 100,000 during this period but was not statistically significant (p=0.345). There was no significant difference in age (p=0.462) and gender (p=0.831) among the patients, but the average CCI significantly increased from 2010 to 2019 (CAGR: +15.30; p=0.001). The total reimbursement in the index (p=0.451) and 90-day bundle period (p=0.191) did not significantly change from 2010 to 2019. Although MAT has been shown to be a safe and reliable surgery for the treatment of meniscus deficient knees, the incidence of MAT as well as the population undergoing MAT has minimally increased from 2010 to 2019. Future studies should seek to identify why the utilization of this efficacious surgery has not increased. IV; Descriptive Epidemiology Study [ABSTRACT FROM AUTHOR]

In American football, hand injuries have been shown to negatively impact performance. The purpose of this study is to characterize the prevalence and severity of hand injuries in National Football League (NFL) players. A public online database was utilized to identify hand injuries in NFL players from 2009–2010 to 2019–2020. The primary outcome was to analyze the overall incidence of hand injuries (including wrist, metacarpus, finger, and thumb), injury type by each aforementioned anatomic location, and player position. Injury severity was evaluated based on percentage of injuries in which players returned to play (RTP), number of games missed before RTP, and the percentage of injuries resulting in the player being placed on injured reserve (IR). Of the 6,127 players included, 847 (13.8%) players sustained a hand injury, of which 24.8%, 34.3%, 17.9%, and 22.9% occurred at the wrist, metacarpus, finger, and thumb, respectively. Of the injured players, 97.4% returned to play following their injury, 14.8% were put on IR, and an average of 1.7 (SD 3.3) games were missed. Quarterbacks were the most likely to sustain hand injuries at all anatomic locations. Wrist injuries were associated with the lowest RTP rate (93.3%), the most players placed on injured reserve (28.6%), and the greatest number of games missed (mean 2.5, SD 4.2). Hand injuries decreased in prevalence by 65.6% over the 11 NFL seasons evaluated. This trend coincides with the implementation of several safety rules that relate to components of play involving the hands. Quarterbacks experienced the greatest prevalence and severity for all hand injuries. Wrist injuries represent the anatomic location associated with the greatest severity. These findings may be able to inform tailored injury prevention practices by position, and advocate for the further adoption of safety rules to protect players from further injury. [ABSTRACT FROM AUTHOR]

Nuclear energy is an important alternative energy source. However, construction of nuclear power plants (NPPs) requires the consideration of environmental, economic, socioeconomic, health, and safety factors since using such an energy source involves some risks during the operation lifetime of a NPP. Accordingly, the selection of the most suitable site for a NPP yields a multicriteria decision making (MCDM) problem. Natural hazards, health hazards, environmental conditions, population density, and the availability of water resources are among the main factors that should be considered. To demonstrate the application of the proposed methodology, two previously identified NPP sites in Turkey, specifically, Mersin-Akkuyu and Sinop-Abalı, are compared utilizing the multicriteria utility functions. In the comparison of these two sites, seismic hazard, tsunami hazard; extreme wind hazard; distance to facilities; population density; proximity to the city center; existence of forests, natural parks, nature conservation areas, and natural monuments; biodiversity; and immovable cultural heritage have been identified as the most important critical criteria and are evaluated concerning the utility functions developed for each criterion. The optimal site is selected within the framework of the MCDM rules, and is recommended as the output of the study. [ABSTRACT FROM AUTHOR]

There is an increasing demand for community-based palliative care services in regional Australia, but feasibility and economic benefits are unclear. This study describes the financial components of service delivery, economic viability from a provider perspective, and potential cost-savings from a health service perspective. We used case study methodology and obtained data from the service provider performance measurement data, annual reports, and internal records. Economic viability included an appraisal of all financial activity, cash on hand, total assets, and liabilities from July 2019 to June 2022. Direct service provision data determined the value for money given total costs and outcomes. Annual cost savings due to decreased utilisation of other healthcare services were estimated using case study data and cost estimates from the literature. The service is largely funded by the government (61%) and community donations & fundraising (34%). Applying a conservative cost estimate based on a reduction of healthcare use (hospitalisations and emergency admissions), cost savings are estimated to range from AU$730 000 to AU$980 000 per year for the cohort of n = 160 clients in the last year of life alone. Average costs per person per year of providing palliative care services were much lower for these clients (AU$6194) compared to the national average for in-home (AU$8000) or hospital-based palliative care services (AU$15 373). The case study site is a viable community-based service but is highly dependent on government funding. It provides excellent value for money from a health service perspective and provides cost saving. Future studies should investigate the generalizability of results. [ABSTRACT FROM AUTHOR]

Experimental studies on animals have demonstrated a higher neuroprotective efficacy of hypercapnic hypoxia compared to normocapnic hypoxia. Respiratory training with hypercapnic hypoxia has shown a positive impact on the functional state of the nervous system in children with cerebral palsy (CP). It can be presumed that the combined effect of moderate hypercapnia and hypoxia will be promising for clinical application within the context of early rehabilitation after ischemic stroke. A randomized triple-blind placebo-controlled study was conducted on 102 patients with ischemic stroke, aged 63.07 ± 12.1 years. All patients were diagnosed with ischemic stroke based on neuroimaging criteria and/or clinical criteria within the 48–72 hour timeframe. The experimental group (n = 50) underwent daily respiratory training with hypercapnic hypoxia (FetCO2 5–6%, FetO2 15–16%) using the 'Carbonic' device for 7–11 sessions of 20 minutes each day during the treatment process. The control group (placebo, n = 52) underwent training on a similar device modified for breathing atmospheric air. Neurological examinations were conducted on all patients before the study and on the day after completing the training course. The standard treatment demonstrated effectiveness in terms of neurological status scales in both groups. Intermittent exposure to hypercapnic hypoxia proved more effective in improving neurological function indicators in patients compared to the placebo group: NIHSS scale scores were 40% lower than in the placebo group (p < 0.001); mRS scale scores were 35% lower (p < 0.001); B-ADL-I and RMI indices were higher by 26% (p < 0.01) and 36% (p < 0.001), respectively; MoCA scale results were 13% higher (p < 0.05); HADS and BDI-II scale scores were lower by 35% (p < 0.05) and 25% (p < 0.05), respectively. The increase in MMSE scale scores in the intervention group was 54% higher (p < 0.001), and MoCA scale scores increased by 25% (p < 0.001). Respiratory training with hypercapnic hypoxia improves the functional state of the nervous system in patients with ischemic stroke. After conducting further clarifying studies, hypercapnic hypoxia can be considered as an effective method of neurorehabilitation, which can be used as early as 48–72 hours after the onset of stroke. [ABSTRACT FROM AUTHOR]

Machine learning can offer an efficient method to identify and map caves, sinkholes, and other cave-like features (i.e. sinkholes, rockshelters, voids) using remotely sensed imagery. While there exists a body of work applying machine learning for sinkhole identification, little work exists for caves. In the densely forested and rugged Maya Lowlands, developing such a methodology can help archaeologists to identify previously unknown caves that may contain important archaeological materials. Here, we introduce a proof-of-concept project that uses random forest and lidar-derived landscape morphometrics to map caves and other cave-like features in northwest Belize. Several undocumented caves and cave-like features were identified in our study area based on model results. Next steps towards making a more robust version of this model include the addition of more training data and integration of a larger number of morphologic parameters. Based on the results described here as well as those in cited works focused on caves, we proposed machine learning as a first step in cave and cave-like feature identification, followed then by fieldwork and ground-truthing. [ABSTRACT FROM AUTHOR]

The present paper describes the experimental setup for flow-induced vibration in a fuel pin bundle test section with flowing lead. The test section is a 37-pin mock-up representative of the GEN-IV ALFRED fuel assembly and is manufactured to investigate the turbulence-induced vibrations in the pins. The pins are instrumented with longitudinal strain gauges (SGs), and with three SGs per monitoring point, the displacement signal can be recovered in terms of amplitude and frequencies. To achieve this goal, a complex algorithm is implemented in the data acquisition control system of the test section. The test section will be installed in the Heavy Liquid metal Experimental loop for Nuclear Applications (HELENA) facility at the ENEA Brasimone R.C., in which a mechanical pump for lead circulation is present. The test matrix is proposed with the mass flow rate varying from 10 to 50 kg/s and a constant temperature of 450°C for all the tests. Briefly, the experimental procedure is presented to carry out the experimental campaign. [ABSTRACT FROM AUTHOR]

Public administration has dedicated much discussion to the ranking of academic journals, but little to no research focused on the quality and contributions of publishing academic books. To address this gap in the literature, we surveyed public administration scholars who have published books. We used the data from this survey to establish a scholarly ranking of book publishers in the field. The findings of the survey show public administration scholars prefer commercial over academic presses when publishing their books. This could be due to the authors' decisions, the publishers seeking and supporting research in public administration, or, most likely, a combination of both. [ABSTRACT FROM AUTHOR]

Potential harms of stationary bike injuries in pediatric patients have been highlighted in the literature, but prior work is limited to case series and without population-level analysis. The purpose of this study is to examine the epidemiology of pediatric stationary bike injuries occurring in the US over the last decade using a national database. Injuries resulting from stationary bike use in pediatric patients from 2012 to 2021 were identified using coding from the National Electronic Injury Surveillance System (NEISS) database. Patient demographics, injury characteristics, and case narratives were examined. National annual estimates of injury frequency/incidence were calculated using weighting and survey package in R. Univariate analyses were used to compare injuries among groups. We identified 525 stationary bike injuries representing an estimated total of 15,509 injuries in the population. Pediatric patients sustained an average of 1,551 injuries annually, with an estimated yearly increase of 288 injuries (p < 0.01) after 2019. While males sustained more injuries, there were age-dependent differences in frequency of injuries between sexes (p < 0.01). The upper extremity was the most commonly injured body region overall, but children 5 and under sustained more injuries to the head/neck. The most common overall injury type was lacerations, while fractures predominated in the 6 to 11-year-old age group. Fifty-six percent of injuries were sustained not while riding the bike, most notably among children under 12. Our findings indicate that the impact of stationary bike injury in the pediatric population is not insignificant, and most injuries are related to improper play rather than traditional exercise use. Gender and age-related patterns differed in regard to the type and mechanism of injury sustained. Children 5 and under sustain a disproportionate amount of injuries to the head, neck, and upper extremity. As stationary bikes grow in popularity, preventative measures should be considered to reduce injuries to young children. [ABSTRACT FROM AUTHOR]

A recipe box collected by Winifred Kowalke of Madison, Wisconsin, in the first half of the 20th century provides a rare glimpse into domesticity in the first half of the twentieth century as technological developments, an evolving convenience-foods industry, and a thriving female network dramatically changed lives, especially those of middle-class women. A careful reading of the cards in the box discloses the impact of new technology on cooking methods, the influence of the emerging commercial market of manufactured foods on the content of the American diet, and the strength of women's networks in sustaining a vibrant female community. Most importantly, it is a story that reaches beyond the ideals presented in women's magazines and contemporary cookbooks to reveal the lived experiences of women in that period. Winifred Kowalke was civic minded. Her recipe box reinforces the image of a woman active in the community and knitted into an extensive, interlacing social network that encompassed a diversity of prominent Madisonians and local cooks. Her friends were community leaders, but their civic and social activities did not divorce them from the domestic world. Her civic and organizational lives melded with her domestic. [ABSTRACT FROM AUTHOR]

Copyright of Kiva is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Studies show a high prevalence of osteoporosis and fracture risk in kidney transplant candidates and recipients. However, little is known about the prevalence of osteoporosis among transplant recipients and candidates living with HIV. To determine the prevalence of osteopenia and osteoporosis and investigate the socio-demographic and nutritional factors associated with BMD in HIV-positive transplant candidates and recipients from an HIV-positive donor. In this cross-sectional study, 20 HIV- positive transplant recipients and 36 transplant candidates on haemodialysis (HD) and awaiting transplantation had BMD and body composition measured by dual-energy X-ray absorptiometry (DEXA). Vitamin D status was measured using serum 25-hydroxyvitamin D [25(OH)D]. Dietary Vitamin D and calcium intake was obtained from a single 24-hour recall. Participants were mainly black African (92.9%), male (55.4%) with a mean age of 43.8 ± 8.3 years. Serum 25(OH)D levels were low for the group as a whole, with a mean of 22.04 ± 12.74 ng/ml. Osteoporosis was more prevalent amongst transplant recipients (20.0%) than transplant candidates (13.9%). Conversely, osteopenia was present amongst transplant candidates (27.8%). T-scores strongly correlated positively, with lean mass and BMD of the spine (r = 0.707, p = 0.007), and moderately, with each side of the total hip BMD (r = 0.455, p = 0.007 and r = 0.420, p = 0.007). There was a significant positive association between dietary calcium and all BMD sites in transplant recipients only. The prevalence of osteoporosis was similar, and in some cases, lower than in transplant recipients elsewhere. Lean mass was positively associated with BMD, and in transplant recipients, dietary calcium intake was positively associated with BMD emphasising the role of diet and exercise in preserving BMD. [ABSTRACT FROM AUTHOR]

The article calls for a shift of educational approaches from colorblind deficit models to asset-based models that reconsider antiracist art educational narratives. Topics discussed include perpetuation of systemic racism with colorblind deficit-oriented positionalities, strategies for transitioning from deficit-based toward asset-based perspectives about Black, Indigenous and people of color (BIPOC) students, and cause and motivation to change White privileging practices.

Solid organ transplant (SOT) recipients with COVID-19 have a higher risk of mortality than those without COVID-19. However, it is unclear how SOT patient outcomes compare to the general population without SOT who contract COVID-19. We used the National Inpatient Sample from January to December 2020 to investigate inpatient outcomes seen in SOT recipients after contracting COVID-19 compared to nontransplant patients. We identified our study sample using ICD-10 CM and excluded those <18 years of age and those with dual organ transplants. Inpatient outcomes were compared in SOT and non-SOT COVID cohorts, and we further evaluated predictors of mortality in the SOT with COVID population. Out of the 1,416,445 COVID-19 admissions included in the study, 8315 (0.59%) were single SOT recipients. Our analysis that adjusted for multiple baseline characteristics and comorbidities demonstrated that COVID-19 in SOT patients was associated with higher rates of acute kidney injury (adjusted odds ratio [aOR] 2.34, 95% confidence interval [CI] 1.81–3.02, P < 0.01), lower rates of acute respiratory distress syndrome (aOR 0.68, 95% CI 0.54–0.85, P < 0.01), and similar rates of cardiac arrest, pulmonary embolism, circulatory shock, cerebrovascular events, and in-hospital mortality. Age >65 was associated with mortality in SOT patients. In this nationally representative sample, SOT patients presenting with COVID-19 experienced similar rates of mortality compared to those without SOT. SOT patients were more likely to develop acute kidney injury. Further research is needed to understand the complex relationship between transplant patient outcomes and COVID-19. [ABSTRACT FROM AUTHOR]

In post-1989 Hungary, as the superstructure of a wellestablished censorship rapidly collapsed, a huge wave of formerly restricted information refreshed the stagnant water of literary and social culture. Nevertheless, the mainstream of contemporary highbrow belles-lettres began to take a rather apolitical approach towards literary production. Realism as an objectivist literary style and referential mode of representation was felt, after 1989, as too ideological, and thus lost its credibility along with the grand narrative of state socialism. A postmodern canon was soon established and popularized, based on formal experimentation and on the non-referential nature of the literary work. Despite the fact that postmodernism generally rejected realist fiction, Hungarian post-communist mainstream writers felt compelled to address the memory of the communist past. This paper aims to investigate major ethical and aesthetical problems of telling the truth via fiction, focusing on seminal books like The Union Jack, Kaddish for an Unborn Child, and Dossier K. by Imre Kertész; as well as Celestial Harmonies and Javított kiadás (Revised Edition) by Péter Esterházy. Last but not least, the article will analyse the compelling piece Egy történet (A/One Story), written by both the aforementioned authors. [ABSTRACT FROM AUTHOR]

When solving nonlinear algebraic equations that arise from discretization using the finite element method (FEM), it is often observed that the standard Newton-Raphson (N-R) iteration either fails to converge or necessitates a large number of iterations in the vicinity of critical points. This work proposes an additional numerical strategy, known as the Potra-Pták iterative cycle, to improve the efficiency of solving highly nonlinear structural problems. Therefore, the focus here is on making the nonlinear solver more robust and efficient, allowing the analysis of more complex nonlinear structures. In the Potra-Pták iterative cycle, two corrections of the objective function (energy function) are performed. The introduction of a second correction in the iterative cycle makes the Potra-Pták strategy more efficient than the standard or modified N-R iterations. This numerical strategy was implemented in the homemade Computational System for Advanced Structural Analysis (CS-ASA) program. The program is based on the FEM and is capable of performing static and dynamic nonlinear analysis of steel, concrete, and composite structures, and its efficiency is then verified through the analysis of slender frames and arches. The algorithm details for solving the nonlinear structural problem, characterized by the Potra-Pták scheme, are provided. [ABSTRACT FROM AUTHOR]

Stories about a submerged land named Lyonesse abound in culture traditions of Southwest Britain and plausibly derive from memories of land loss within the Scilly Isles. We review Lyonesse stories, their links to Arthurian romances and Greek/Roman accounts of the Cassiterides, and trace their divergent evolution. From this region's history of land-sea movements and human occupation, we propose Lyonesse stories originated more than 4000 years ago when rising sea level divided a single inhabited island in the Scilly group. The comparable antiquity of similar stories is a compelling reason for supposing Lyonesse stories originated from observations of submergence encoded in cultural memories through oral traditions that endured in intelligible form for several millennia to reach us today. [ABSTRACT FROM AUTHOR]

Copyright of Atmosphere -- Ocean (Taylor & Francis Ltd) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Despite recent advances, the prognosis for primary malignant brain tumors (PMBTs) remains poor. Some commonly prescribed medications may exhibit anti-tumor properties in various cancers, and neurodegenerative diseases may activate pathways that counteract gliomagenesis. Our study is focused on determining if there is a correlation between the use of metformin, beta-blockers, angiotensin converting enzyme inhibitors (ACEIs), and angiotensin receptor blockers (ARBs), or the presence of Parkinson's disease (PD), and the survival rates following a diagnosis of a PMBT. This analysis of the 100% Texas Medicare Database identified patients aged 66+ years diagnosed with a supratentorial PMBT from 2014–2017. Cox proportional hazards regression was employed to analyze survival following diagnosis and associations of survival with surgical intervention, radiation, PD diagnosis, and prescription of metformin, beta-blockers, ACEIs, or ARBs. There were 1,943 patients who met study criteria, and the median age was 74 years. When medication utilization was stratified by none, pre-diagnosis only, post-diagnosis only, or both pre- and post-diagnosis (continuous), continuous utilization of metformin, beta-blockers, ACEIs, or ARBs was associated with prolonged survival compared to no utilization (hazard ratio [HR]:0.45, 95% CI:0.33–0.62; HR:0.71. 95% CI:0.59–0.86; HR:0.59, 95% CI:0.48–0.72; and HR:0.45, 95% CI:0.35–0.58 respectively). PD was also associated with longer survival (HR:0.59–0.63 across the four models). Our study suggests that metformin, beta-blockers, ACEIs, ARBs, and comorbid PD are associated with a survival benefit among geriatric Medicare patients with supratentorial PMBTs. [ABSTRACT FROM AUTHOR]

Copyright of Journal of the American Institute for Conservation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The Arboricultural Journal's third issue of 2024 features articles and research on various urban forest issues from around the world. One article explores the potential benefits of planting trees in urban areas to aid in the northward movement of trees due to anthropogenic warming and urban heat island effects. Other articles discuss topics such as the establishment of saplings for urban planting programs, the response of urban plantations to climatic and edaphic conditions, the historical cultural management of crack willow in Italy, and the growth of Picea seedlings with humic applications. Additionally, a research note examines the community usage of trees for firewood in Georgia and the challenges of sustainable resource management. The journal emphasizes the importance of effective research and professional practice in managing trees and forests for climate resilience, carbon capture, biodiversity, and local economies. [Extracted from the article]

Two essential questions for those leading the field of public administration are: What do we teach our students, and how do we train them? As scholars, we pay significant attention to our research, often to the detriment of recognizing the potential for merging our research with teaching through the Scholarship of Teaching and Learning (SoTL). However, given our students' leadership positions, SoTL-related work is vital to their success. In this article, we have come together to reflect on the state of SoTL's work in public administration. Through this reflection, we explore the windows of opportunity for research that we see emerging. Included among these opportunities is the need for research on how we can best serve students in and out of the classroom, as well as research the most effective way of managing our programs. We also see the need for research into faculty development, instructional design, and the return on investment for a public administration degree. Lastly, we argue for improved recognition of the value and contribution of SoTL-related work in tenure and promotion standards. [ABSTRACT FROM AUTHOR]

To examine the relationship in dairy cattle between serum and faecal Zn concentrations and daily intake of Zn supplemented with an oral drench; and whether total daily intake (TDI) of Zn in dairy cattle can be predicted from single measurements of Zn concentration in serum or faeces. A convenience sample of 20 animals from three stock classes (lactating cows, dry cows, heifers), that had not received Zn supplementation in the previous 60 days, was enrolled in the study. From Days −7 to −1, animals received no Zn supplementation. On Day 0, 15 animals per class were assigned daily drenching with increasing doses of ZnSO4.7H2O while five remained controls. From Days 0–6, treatment animals received 12.5 mg/kg LWT of Zn/day; from Days 7–13, 25 mg/kg LWT Zn/day and from Days 14–20, 37.5 mg/kg LWT Zn/day. Animals co-grazed within each stock class. Pasture, serum and faecal samples were collected at the start and at weekly intervals before each increase in Zn supplementation. Mixed and non-parametric models were used to assess treatment effects and whether daily intake of Zn could be predicted from Zn concentrations in serum and faeces. Dosing with 0, 12.5, 25.0 and 37.5 mg Zn/kg LWT resulted in serum Zn concentrations of 12.1, 16.7, 27.2 and 35.8 µmol/L in heifers, 13.3, 17.1, 26.4 and 40.0 µmol/L in dry and 11.9, 12.1, 23.4 and 27.2 µmol/L in lactating cows. Dosing with the same amounts of Zn resulted in faecal Zn concentrations of 2.95, 21.72, 40.32 and 53.27 mmol/kg DM in heifers, 2.81, 23.77, 55.16 and 68.20 mmol/kg DM in dry and 3.00, 12.71, 34.86 and 57.53 mmol/kg DM in lactating cows, respectively. Treatment elevated serum and faecal Zn concentrations above controls (p < 0.001). Supplemented lactating cows had lower serum Zn concentrations than dry cows or heifers (p < 0.01). Supplemented dry cows had faecal DM Zn concentrations higher than heifers or lactating cows (p < 0.05). Analysis showed serum and faecal Zn concentrations could predict TDI of Zn (p < 0.001). Concentrations of Zn in faeces estimated TDI of Zn within a narrower predictive interval than serum Zn concentrations. Concentrations of Zn in serum and faeces were positively associated with TDI of Zn in dairy cattle and could predict TDI of Zn. When using serum and faecal Zn concentrations to estimate TDI Zn, stock class must be accounted for. [ABSTRACT FROM AUTHOR]

FDM is a prominent AM process from which 3D models can be generated. Optimisation algorithms are used to get best levels of process parameters. The aim of this article is to analyse statistically the L16 OA and its corresponding responses in order to obtain optimal process parameter level combinations which could make the product efficient. The process parameters considered were extrusion temperature and infill density. The optimal parameter settings obtained were an extrusion temperature of 220°C and an infill density of 80%. Each parameter was considered at four different levels. Since there were two factors at four levels, L16 OA was preferred to design the experimental plan. The process parameters were selected based on the output responses. A total of 16 samples for each response were manufactured and tested, and statistical analysis was carried out. Statistical approaches like ANOVA analysis and S/N ratio analysis were used to get significance of factors and optimal parameter settings, and analysis was performed using MINITAB 16. Validation tests were carried out with optimal parameter settings as input parameters. Statistical analysis showed that extrusion temperature was a more significant factor compared to infill density for both tensile and compressive strengths. [ABSTRACT FROM AUTHOR]

Phage therapy has recently attracted a great deal of attention to counteract the rapid emergence of antibiotic-resistant bacteria. In comparison to monophage therapy, phage cocktails are typically used to treat individual and/or multi-bacterial infections since the bacterial agents are unlikely to become resistant as a result of exposure to multiple phages simultaneously. The bacteriolytic effect of phage cocktails may produce efficient killing effect in comparison to individual phage. However, multiple use of phages (complex cocktails) may lead to undesirable side effects such as dysbiosis, horizontal gene transfer, phage resistance, cross resistance, and/or higher cost of production. Cocktail formulation, therefore, representa compromise between limiting the complexity of the cocktail and achieving substantial bacterial load reduction towards the targeted host organisms. Despite some constraints, the applications of monophage therapy have been well documented in the literature. However, phage cocktails-based approaches and their role for the control of pathogens have not been well investigated. In this review, we discuss the principle of phage cocktail formulations, their optimization strategies, major phage cocktail preparations, and their efficacy in inactivating various food borne bacterial pathogens. [ABSTRACT FROM AUTHOR]